Product References
Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis.
Science advances
Zhu CS,Qiang X,Chen W,Li J,Lan X,Yang H,Gong J,Becker L,Wang P,Tracey KJ,Wang H
300-13 was used in Cell Culture to suggest a possibility of developing antibody strategies to prevent dysregulated immune responses mediated by late-acting cytokines.
Fri Feb 03 00:00:00 EST 2023
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.
Cell death and differentiation
Fernández-Duran I,Quintanilla A,Tarrats N,Birch J,Hari P,Millar FR,Lagnado AB,Smer-Barreto V,Muir M,Brunton VG,Passos JF,Acosta JC
300-13 was used in Cell Culture to evidence that recognition of cytoplasmic LPS by the noncanonical inflammosome caspase-4 induces cellular senescence; a typical cellular response pathway during oncogenic stress.
Wed Jun 01 00:00:00 EDT 2022
Cytoplasmic innate immune sensing by the caspase-4 non-canonical inflammasome promotes cellular senescence.
Cell death and differentiation
Fernández-Duran I,Quintanilla A,Tarrats N,Birch J,Hari P,Millar FR,Lagnado AB,Smer-Barreto V,Muir M,Brunton VG,Passos JF,Acosta JC
300-13 was used in Cell Culture to evidence that recognition of cytoplasmic LPS by the noncanonical inflammosome caspase-4 induces cellular senescence; a typical cellular response pathway during oncogenic stress.
Wed Jun 01 00:00:00 EDT 2022
Accelerated atherosclerosis caused by serum amyloid A response in lungs of ApoE-/- mice.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Christophersen DV,Møller P,Thomsen MB,Lykkesfeldt J,Loft S,Wallin H,Vogel U,Jacobsen NR
Mon Mar 01 00:00:00 EST 2021
Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification.
The FEBS journal
Yu S,Green J,Wellens R,Lopez-Castejon G,Brough D
Sat May 01 00:00:00 EDT 2021
Native and oxidised lipoproteins negatively regulate the serum amyloid A-induced NLRP3 inflammasome activation in human macrophages.
Clinical & translational immunology
Nurmi K,Niemi K,Kareinen I,Silventoinen K,Lorey MB,Chen Y,Kouri VP,Parantainen J,Juutilainen T,Öörni K,Kovanen PT,Nordström D,Matikainen S,Eklund KK
Mon Apr 25 00:00:00 EDT 2022
Native and oxidised lipoproteins negatively regulate the serum amyloid A-induced NLRP3 inflammasome activation in human macrophages.
Clinical & translational immunology
Nurmi K,Niemi K,Kareinen I,Silventoinen K,Lorey MB,Chen Y,Kouri VP,Parantainen J,Juutilainen T,Öörni K,Kovanen PT,Nordström D,Matikainen S,Eklund KK
Mon Apr 25 00:00:00 EDT 2022
Dual modulation of formyl peptide receptor 2 by aspirin-triggered lipoxin contributes to its anti-inflammatory activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Ge Y,Zhang S,Wang J,Xia F,Wan JB,Lu J,Ye RD
Fri May 01 00:00:00 EDT 2020
Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis.
Nature communications
Montero-Melendez T,Nagano A,Chelala C,Filer A,Buckley CD,Perretti M
Thu Feb 06 00:00:00 EST 2020
Dysfunctional high-density lipoprotein activates toll-like receptors via serum amyloid A in vascular smooth muscle cells.
Scientific reports
Schuchardt M,Prüfer N,Tu Y,Herrmann J,Hu XP,Chebli S,Dahlke K,Zidek W,van der Giet M,Tölle M
Mon Mar 04 00:00:00 EST 2019
Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis.
Scientific reports
Chen W,Zhu S,Wang Y,Li J,Qiang X,Zhao X,Yang H,D'Angelo J,Becker L,Wang P,Tracey KJ,Wang H
Thu Jan 17 00:00:00 EST 2019
IFN-β is a macrophage-derived effector cytokine facilitating the resolution of bacterial inflammation.
Nature communications
Kumaran Satyanarayanan S,El Kebir D,Soboh S,Butenko S,Sekheri M,Saadi J,Peled N,Assi S,Othman A,Schif-Zuck S,Feuermann Y,Barkan D,Sher N,Filep JG,Ariel A
Fri Aug 02 00:00:00 EDT 2019
Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A.
Journal of immunology (Baltimore, Md. : 1950)
Burgess EJ,Hoyt LR,Randall MJ,Mank MM,Bivona JJ,Eisenhauer PL,Botten JW,Ballif BA,Lam YW,Wargo MJ,Boyson JE,Ather JL,Poynter ME
Mon Oct 15 00:00:00 EDT 2018
Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A.
Journal of immunology (Baltimore, Md. : 1950)
Burgess EJ,Hoyt LR,Randall MJ,Mank MM,Bivona JJ,Eisenhauer PL,Botten JW,Ballif BA,Lam YW,Wargo MJ,Boyson JE,Ather JL,Poynter ME
Mon Oct 15 00:00:00 EDT 2018
Connexin 43 Hemichannel as a Novel Mediator of Sterile and Infectious Inflammatory Diseases.
Scientific reports
Li W,Bao G,Chen W,Qiang X,Zhu S,Wang S,He M,Ma G,Ochani M,Al-Abed Y,Yang H,Tracey KJ,Wang P,D'Angelo J,Wang H
Tue Jan 09 00:00:00 EST 2018
Serum amyloid A inhibits dendritic cell differentiation by suppressing GM-CSF receptor expression and signaling.
Experimental & molecular medicine
Kim JC,Jung YS,Lee HY,Park JS,Bae YS
Fri Aug 25 00:00:00 EDT 2017
Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A.
Scientific reports
Barbierato M,Borri M,Facci L,Zusso M,Skaper SD,Giusti P
Fri Sep 22 00:00:00 EDT 2017
Ethanol and Other Short-Chain Alcohols Inhibit NLRP3 Inflammasome Activation through Protein Tyrosine Phosphatase Stimulation.
Journal of immunology (Baltimore, Md. : 1950)
Hoyt LR,Ather JL,Randall MJ,DePuccio DP,Landry CC,Wewers MD,Gavrilin MA,Poynter ME
Mon Aug 15 00:00:00 EDT 2016
Serum amyloid A inhibits RANKL-induced osteoclast formation.
Experimental & molecular medicine
Oh E,Lee HY,Kim HJ,Park YJ,Seo JK,Park JS,Bae YS
Fri Nov 13 00:00:00 EST 2015
Serum amyloid A inhibits RANKL-induced osteoclast formation.
Experimental & molecular medicine
Oh E,Lee HY,Kim HJ,Park YJ,Seo JK,Park JS,Bae YS
Fri Nov 13 00:00:00 EST 2015
Serum Amyloid A Stimulates PKR Expression and HMGB1 Release Possibly through TLR4/RAGE Receptors.
Molecular medicine (Cambridge, Mass.)
Li W,Zhu S,Li J,D'Amore J,D'Angelo J,Yang H,Wang P,Tracey KJ,Wang H
300-13 was used in Cell Culture to investigate molecular mechanisms of sepsis.
Tue Jun 02 00:00:00 EDT 2015
Ex vivo and in vitro effect of serum amyloid a in the induction of macrophage M2 markers and efferocytosis of apoptotic neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Sun L,Zhou H,Zhu Z,Yan Q,Wang L,Liang Q,Ye RD
Fri May 15 00:00:00 EDT 2015
Ex vivo and in vitro effect of serum amyloid a in the induction of macrophage M2 markers and efferocytosis of apoptotic neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Sun L,Zhou H,Zhu Z,Yan Q,Wang L,Liang Q,Ye RD
Fri May 15 00:00:00 EDT 2015
Ex vivo and in vitro effect of serum amyloid a in the induction of macrophage M2 markers and efferocytosis of apoptotic neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Sun L,Zhou H,Zhu Z,Yan Q,Wang L,Liang Q,Ye RD
Fri May 15 00:00:00 EDT 2015
Apolipoprotein-A1 as a damage-associated molecular patterns protein in osteoarthritis: ex vivo and in vitro pro-inflammatory properties.
PloS one
de Seny D,Cobraiville G,Charlier E,Neuville S,Lutteri L,Le Goff C,Malaise D,Malaise O,Chapelle JP,Relic B,Malaise MG
300-13 was used in Cell Culture to study the role of apolipoprotein A-I (ApoA1) in vitro on inflammatory parameters using human joint cells isolated from cartilage and synovial membrane obtained from osteoarthritis (OA) patients after joint replacement.
Mon Jan 04 00:00:00 EST 2016
Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proceedings of the National Academy of Sciences of the United States of America
Lu J,Yu Y,Zhu I,Cheng Y,Sun PD
Tue Apr 08 00:00:00 EDT 2014
Structural mechanism of serum amyloid A-mediated inflammatory amyloidosis.
Proceedings of the National Academy of Sciences of the United States of America
Lu J,Yu Y,Zhu I,Cheng Y,Sun PD
Tue Apr 08 00:00:00 EDT 2014
Cutting edge: An inactive chromatin configuration at the IL-10 locus in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Tamassia N,Zimmermann M,Castellucci M,Ostuni R,Bruderek K,Schilling B,Brandau S,Bazzoni F,Natoli G,Cassatella MA
Fri Mar 01 00:00:00 EST 2013
Cutting edge: An inactive chromatin configuration at the IL-10 locus in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950)
Tamassia N,Zimmermann M,Castellucci M,Ostuni R,Bruderek K,Schilling B,Brandau S,Bazzoni F,Natoli G,Cassatella MA
Fri Mar 01 00:00:00 EST 2013
Serum amyloid A inhibits dendritic cell apoptosis to induce glucocorticoid resistance in CD4(+) T cells.
Cell death & disease
Ather JL,Fortner KA,Budd RC,Anathy V,Poynter ME
Thu Sep 05 00:00:00 EDT 2013
Endogenous Acute Phase Serum Amyloid A Lacks Pro-Inflammatory Activity, Contrasting the Two Recombinant Variants That Activate Human Neutrophils through Different Receptors.
Frontiers in immunology
Christenson K,Björkman L,Ahlin S,Olsson M,Sjöholm K,Karlsson A,Bylund J
300-13 was used in In vitro experiments to study whether endogenous acute phase serum amyloid A (SAA) mediates pro-inflammatory effects.
Tue Apr 30 00:00:00 EDT 2013
Serum amyloid A opposes lipoxin A₄ to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease.
Proceedings of the National Academy of Sciences of the United States of America
Bozinovski S,Uddin M,Vlahos R,Thompson M,McQualter JL,Merritt AS,Wark PA,Hutchinson A,Irving LB,Levy BD,Anderson GP
Tue Jan 17 00:00:00 EST 2012
Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts.
Arthritis research & therapy
Migita K,Koga T,Satomura K,Izumi M,Torigoshi T,Maeda Y,Izumi Y,Jiuchi Y,Miyashita T,Yamasaki S,Aiba Y,Komori A,Nakamura M,Motokawa S,Kawakami A,Nakamura T,Ishibashi H
Fri May 18 00:00:00 EDT 2012
Serum amyloid A is a growth factor for 3T3-L1 adipocytes, inhibits differentiation and promotes insulin resistance.
International journal of obesity (2005)
Filippin-Monteiro FB,de Oliveira EM,Sandri S,Knebel FH,Albuquerque RC,Campa A
Wed Aug 01 00:00:00 EDT 2012
Annexin A1 N-terminal derived Peptide ac2-26 exerts chemokinetic effects on human neutrophils.
Frontiers in pharmacology
Dalli J,Montero-Melendez T,McArthur S,Perretti M
Tue Oct 02 00:00:00 EDT 2012
Uropathogenic Escherichia coli induces serum amyloid a in mice following urinary tract and systemic inoculation.
PloS one
Erman A,Lakota K,Mrak-Poljsak K,Blango MG,Krizan-Hergouth V,Mulvey MA,Sodin-Semrl S,Veranic P
Mon Aug 20 00:00:00 EDT 2012
Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling.
The Journal of biological chemistry
Bena S,Brancaleone V,Wang JM,Perretti M,Flower RJ
Fri Jul 13 00:00:00 EDT 2012
The acute phase protein Serum Amyloid A induces lipolysis and inflammation in human adipocytes through distinct pathways.
PloS one
Faty A,Ferré P,Commans S
Fri Aug 03 00:00:00 EDT 2012
Serum amyloid A overrides Treg anergy via monocyte-dependent and Treg-intrinsic, SOCS3-associated pathways.
Blood
Nguyen KD,Macaubas C,Nadeau KC,Truong P,Yoon T,Lee T,Park JL,Mellins ED
Thu Apr 07 00:00:00 EDT 2011
Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.
Journal of immunology (Baltimore, Md. : 1950)
Ather JL,Ckless K,Martin R,Foley KL,Suratt BT,Boyson JE,Fitzgerald KA,Flavell RA,Eisenbarth SC,Poynter ME
Fri Jul 01 00:00:00 EDT 2011
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.
Journal of immunology (Baltimore, Md. : 1950)
Niemi K,Teirilä L,Lappalainen J,Rajamäki K,Baumann MH,Öörni K,Wolff H,Kovanen PT,Matikainen S,Eklund KK
Wed Jun 01 00:00:00 EDT 2011
Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.
Journal of immunology (Baltimore, Md. : 1950)
Niemi K,Teirilä L,Lappalainen J,Rajamäki K,Baumann MH,Öörni K,Wolff H,Kovanen PT,Matikainen S,Eklund KK
Wed Jun 01 00:00:00 EDT 2011
Colocalization of serum amyloid a with microtubules in human coronary artery endothelial cells.
Journal of biomedicine & biotechnology
Lakota K,Resnik N,Mrak-Poljšak K,Sodin-Šemrl S,Veranič P
Thu Mar 22 00:00:00 EDT 2012
Serum amyloid A regulates granulomatous inflammation in sarcoidosis through Toll-like receptor-2.
American journal of respiratory and critical care medicine
Chen ES,Song Z,Willett MH,Heine S,Yung RC,Liu MC,Groshong SD,Zhang Y,Tuder RM,Moller DR
Mon Feb 15 00:00:00 EST 2010
Hepatic acute-phase proteins control innate immune responses during infection by promoting myeloid-derived suppressor cell function.
The Journal of experimental medicine
Sander LE,Sackett SD,Dierssen U,Beraza N,Linke RP,Müller M,Blander JM,Tacke F,Trautwein C
Mon Jul 05 00:00:00 EDT 2010
Acute serum amyloid A induces migration, angiogenesis, and inflammation in synovial cells in vitro and in a human rheumatoid arthritis/SCID mouse chimera model.
Journal of immunology (Baltimore, Md. : 1950)
Connolly M,Marrelli A,Blades M,McCormick J,Maderna P,Godson C,Mullan R,FitzGerald O,Bresnihan B,Pitzalis C,Veale DJ,Fearon U
Tue Jun 01 00:00:00 EDT 2010
Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Dufton N,Hannon R,Brancaleone V,Dalli J,Patel HB,Gray M,D'Acquisto F,Buckingham JC,Perretti M,Flower RJ
Mon Mar 01 00:00:00 EST 2010
Secretory phospholipase A2, group IIA is a novel serum amyloid A target gene: activation of smooth muscle cell expression by an interleukin-1 receptor-independent mechanism.
The Journal of biological chemistry
Sullivan CP,Seidl SE,Rich CB,Raymondjean M,Schreiber BM
Fri Jan 01 00:00:00 EST 2010
CD36 is a novel serum amyloid A (SAA) receptor mediating SAA binding and SAA-induced signaling in human and rodent cells.
The Journal of biological chemistry
Baranova IN,Bocharov AV,Vishnyakova TG,Kurlander R,Chen Z,Fu D,Arias IM,Csako G,Patterson AP,Eggerman TL
Fri Mar 12 00:00:00 EST 2010
Induction of intestinal Th17 cells by segmented filamentous bacteria.
Cell
Ivanov II,Atarashi K,Manel N,Brodie EL,Shima T,Karaoz U,Wei D,Goldfarb KC,Santee CA,Lynch SV,Tanoue T,Imaoka A,Itoh K,Takeda K,Umesaki Y,Honda K,Littman DR
Fri Oct 30 00:00:00 EDT 2009
Serum amyloid A induces G-CSF expression and neutrophilia via Toll-like receptor 2.
Blood
He RL,Zhou J,Hanson CZ,Chen J,Cheng N,Ye RD
Thu Jan 08 00:00:00 EST 2009
Serum amyloid A induces monocyte tissue factor.
Journal of immunology (Baltimore, Md. : 1950)
Cai H,Song C,Endoh I,Goyette J,Jessup W,Freedman SB,McNeil HP,Geczy CL
Thu Feb 01 00:00:00 EST 2007
Serum amyloid A generates high density lipoprotein with cellular lipid in an ABCA1- or ABCA7-dependent manner.
Journal of lipid research
Abe-Dohmae S,Kato KH,Kumon Y,Hu W,Ishigami H,Iwamoto N,Okazaki M,Wu CA,Tsujita M,Ueda K,Yokoyama S
300-13 was used in Cell Culture to investigate serum amyloid A and inflammation in disease.
Sat Jul 01 00:00:00 EDT 2006
Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I.
The Journal of biological chemistry
van der Westhuyzen DR,Cai L,de Beer MC,de Beer FC
Fri Oct 28 00:00:00 EDT 2005
