Product References
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
300-21 was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Cell
Bouhaddou M,Memon D,Meyer B,White KM,Rezelj VV,Correa Marrero M,Polacco BJ,Melnyk JE,Ulferts S,Kaake RM,Batra J,Richards AL,Stevenson E,Gordon DE,Rojc A,Obernier K,Fabius JM,Soucheray M,Miorin L,Moreno E,Koh C,Tran QD,Hardy A,Robinot R,Vallet T,Nilsson-Payant BE,Hernandez-Armenta C,Dunham A,Weigang S,Knerr J,Modak M,Quintero D,Zhou Y,Dugourd A,Valdeolivas A,Patil T,Li Q,Hüttenhain R,Cakir M,Muralidharan M,Kim M,Jang G,Tutuncuoglu B,Hiatt J,Guo JZ,Xu J,Bouhaddou S,Mathy CJP,Gaulton A,Manners EJ,Félix E,Shi Y,Goff M,Lim JK,McBride T,O'Neal MC,Cai Y,Chang JCJ,Broadhurst DJ,Klippsten S,De Wit E,Leach AR,Kortemme T,Shoichet B,Ott M,Saez-Rodriguez J,tenOever BR,Mullins RD,Fischer ER,Kochs G,Grosse R,García-Sastre A,Vignuzzi M,Johnson JR,Shokat KM,Swaney DL,Beltrao P,Krogan NJ
300-21 was used in Enzyme-linked immunosorbent assay to present a quantitative mass spectrometry-based phosphoproteomics survey of SARS-CoV-2 infection in Vero E6 cells, revealing dramatic rewiring of phosphorylation on host and viral proteins.
Thu Aug 06 00:00:00 EDT 2020
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
The Journal of biological chemistry
Lee AW,Deruaz M,Lynch C,Davies G,Singh K,Alenazi Y,Eaton JRO,Kawamura A,Shaw J,Proudfoot AEI,Dias JM,Bhattacharya S
Fri Jul 19 00:00:00 EDT 2019
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer.
Cancer cell
Costa A,Kieffer Y,Scholer-Dahirel A,Pelon F,Bourachot B,Cardon M,Sirven P,Magagna I,Fuhrmann L,Bernard C,Bonneau C,Kondratova M,Kuperstein I,Zinovyev A,Givel AM,Parrini MC,Soumelis V,Vincent-Salomon A,Mechta-Grigoriou F
Mon Mar 12 00:00:00 EDT 2018
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Scientific reports
Alenazi Y,Singh K,Davies G,Eaton JRO,Elders P,Kawamura A,Bhattacharya S
Fri Apr 20 00:00:00 EDT 2018
A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma.
Scientific reports
Zhang Y,Wu Y,Qi H,Xiao J,Gong H,Zhang Y,Xu E,Li S,Ma D,Wang Y,Li W,Shen H
Wed Nov 08 00:00:00 EST 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
The analysis of heterotaxy patients reveals new loss-of-function variants of GRK5.
Scientific reports
Lessel D,Muhammad T,Casar Tena T,Moepps B,Burkhalter MD,Hitz MP,Toka O,Rentzsch A,Schubert S,Schalinski A,Bauer UM,Kubisch C,Ware SM,Philipp M
Tue Sep 13 00:00:00 EDT 2016
A biased non-Gαi OXE-R antagonist demonstrates that Gαi protein subunit is not directly involved in neutrophil, eosinophil, and monocyte activation by 5-oxo-ETE.
Journal of immunology (Baltimore, Md. : 1950)
Konya V,Blättermann S,Jandl K,Platzer W,Ottersbach PA,Marsche G,Gütschow M,Kostenis E,Heinemann A
Thu May 15 00:00:00 EDT 2014
Priming of eosinophils by GM-CSF is mediated by protein kinase CbetaII-phosphorylated L-plastin.
Journal of immunology (Baltimore, Md. : 1950)
Pazdrak K,Young TW,Straub C,Stafford S,Kurosky A
Wed Jun 01 00:00:00 EDT 2011
Host chemokines bind to Staphylococcus aureus and stimulate protein A release.
The Journal of biological chemistry
Yung SC,Parenti D,Murphy PM
Fri Feb 18 00:00:00 EST 2011
Role of the CXCR4/CXCL12 axis in lymphangioleiomyomatosis and angiomyolipoma.
Journal of immunology (Baltimore, Md. : 1950)
Clements D,Markwick LJ,Puri N,Johnson SR
Sun Aug 01 00:00:00 EDT 2010
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Nature
Takeda A,Baffi JZ,Kleinman ME,Cho WG,Nozaki M,Yamada K,Kaneko H,Albuquerque RJ,Dridi S,Saito K,Raisler BJ,Budd SJ,Geisen P,Munitz A,Ambati BK,Green MG,Ishibashi T,Wright JD,Humbles AA,Gerard CJ,Ogura Y,Pan Y,Smith JR,Grisanti S,Hartnett ME,Rothenberg ME,Ambati J
Thu Jul 09 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid.
Blood
Spiegl N,Didichenko S,McCaffery P,Langen H,Dahinden CA
Sat Nov 01 00:00:00 EDT 2008
Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
Journal of immunology (Baltimore, Md. : 1950)
Sturm EM,Schratl P,Schuligoi R,Konya V,Sturm GJ,Lippe IT,Peskar BA,Heinemann A
Sat Nov 15 00:00:00 EST 2008
The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
Stem cells (Dayton, Ohio)
Ponte AL,Marais E,Gallay N,Langonné A,Delorme B,Hérault O,Charbord P,Domenech J
Sun Jul 01 00:00:00 EDT 2007
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils.
Blood
Munitz A,Bachelet I,Eliashar R,Moretta A,Moretta L,Levi-Schaffer F
Wed Mar 01 00:00:00 EST 2006
Autoantigens signal through chemokine receptors: uveitis antigens induce CXCR3- and CXCR5-expressing lymphocytes and immature dendritic cells to migrate.
Blood
Howard OM,Dong HF,Su SB,Caspi RR,Chen X,Plotz P,Oppenheim JJ
Wed Jun 01 00:00:00 EDT 2005
Identification of selective basophil chemoattractants in human nasal polyps as insulin-like growth factor-1 and insulin-like growth factor-2.
Journal of immunology (Baltimore, Md. : 1950)
Hartnell A,Heinemann A,Conroy DM,Wait R,Sturm GJ,Caversaccio M,Jose PJ,Williams TJ
Mon Nov 15 00:00:00 EST 2004
IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression.
Journal of immunology (Baltimore, Md. : 1950)
Ferland C,Flamand N,Davoine F,Chakir J,Laviolette M
Fri Oct 01 00:00:00 EDT 2004
Responses of leukocytes to chemokines in whole blood and their antagonism by novel CC-chemokine receptor 3 antagonists.
American journal of respiratory and critical care medicine
Bryan SA,Jose PJ,Topping JR,Wilhelm R,Soderberg C,Kertesz D,Barnes PJ,Williams TJ,Hansel TT,Sabroe I
Sat Jun 15 00:00:00 EDT 2002
A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.
The Journal of biological chemistry
Sabroe I,Peck MJ,Van Keulen BJ,Jorritsma A,Simmons G,Clapham PR,Williams TJ,Pease JE
Fri Aug 25 00:00:00 EDT 2000
A small molecule antagonist of chemokine receptors CCR1 and CCR3. Potent inhibition of eosinophil function and CCR3-mediated HIV-1 entry.
The Journal of biological chemistry
Sabroe I,Peck MJ,Van Keulen BJ,Jorritsma A,Simmons G,Clapham PR,Williams TJ,Pease JE
Fri Aug 25 00:00:00 EDT 2000
Differential activation of CC chemokine receptors by AOP-RANTES.
The Journal of biological chemistry
Elsner J,Mack M,Brühl H,Dulkys Y,Kimmig D,Simmons G,Clapham PR,Schlöndorff D,Kapp A,Wells TN,Proudfoot AE
Fri Mar 17 00:00:00 EST 2000
CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3.
Journal of immunology (Baltimore, Md. : 1950)
Struyf S,Proost P,Schols D,De Clercq E,Opdenakker G,Lenaerts JP,Detheux M,Parmentier M,De Meester I,Scharpé S,Van Damme J
Thu Apr 15 00:00:00 EDT 1999
Chemokines and the arrest of lymphocytes rolling under flow conditions.
Science (New York, N.Y.)
Campbell JJ,Hedrick J,Zlotnik A,Siani MA,Thompson DA,Butcher EC
Fri Jan 16 00:00:00 EST 1998
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
The Journal of experimental medicine
Tiffany HL,Lautens LL,Gao JL,Pease J,Locati M,Combadiere C,Modi W,Bonner TI,Murphy PM
Mon Jul 07 00:00:00 EDT 1997
Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage.
The Journal of experimental medicine
Oravecz T,Pall M,Roderiquez G,Gorrell MD,Ditto M,Nguyen NY,Boykins R,Unsworth E,Norcross MA
Mon Dec 01 00:00:00 EST 1997
