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Product Details
300-36-20UG
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Published species
Bacteria,
Hamster,
Human,
Mouse
Expression System
E. coli
Amino acid sequence
YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
Molecular weight
8 kDa
Class
Recombinant
Type
Protein
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin concentration
<1 EU/µg
Activity
Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient
Product Specific Information
Recombinant Human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AW060611; C-C motif chemokine 22; CC chemokine STCP-1; chemokine (C-C motif) ligand 22; Macrophage-derived chemokine; MDC(1-69); MGC108943; MGC34554; RP24-69A20.1; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; Small-inducible cytokine A22; stimulated T cell chemotactic protein 1; Stimulated T-cell chemotactic protein 1
Gene Aliases: A-152E5.1; ABCD-1; CCL22; DC/B-CK; MDC; SCYA22; STCP-1
UniProt ID: (Human) O00626
Entrez Gene ID: (Human) 6367
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