Product References
Indoleamine 2, 3-Dioxygenase 1 Mediates Survival Signals in Chronic Lymphocytic Leukemia via Kynurenine/Aryl Hydrocarbon Receptor-Mediated MCL1 Modulation.
Frontiers in immunology
Atene CG,Fiorcari S,Mesini N,Alboni S,Martinelli S,Maccaferri M,Leonardi G,Potenza L,Luppi M,Maffei R,Marasca R
310-02 was used in In vitro experiments to study the functional role of the IDO1/Kyn/AHR axis in chronic lymphocytic leukemia (CLL).
Fri Apr 08 00:00:00 EDT 2022
SDF-1α Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia.
Stem cells international
Chen Z,Zhou S,Li J,Li H,Huang C,Guo Q,Zhang T,Yang B,Tu C,Guo C
Fri Nov 19 00:00:00 EST 2021
SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses.
Cell reports. Medicine
Mandolesi M,Sheward DJ,Hanke L,Ma J,Pushparaj P,Perez Vidakovics L,Kim C,Àdori M,Lenart K,Loré K,Castro Dopico X,Coquet JM,McInerney GM,Karlsson Hedestam GB,Murrell B
Tue Apr 20 00:00:00 EDT 2021
DAPK3 participates in the mRNA processing of immediate early genes in chronic lymphocytic leukaemia.
Molecular oncology
Thomas F,Holmes KB,Kreuz S,Hillmen P,Lefevre PF
Mon Jun 01 00:00:00 EDT 2020
CD40L membrane retention enhances the immunostimulatory effects of CD40 ligation.
Scientific reports
Elmetwali T,Salman A,Wei W,Hussain SA,Young LS,Palmer DH
Wed Jan 15 00:00:00 EST 2020
Class-Switch Recombination Occurs Infrequently in Germinal Centers.
Immunity
Roco JA,Mesin L,Binder SC,Nefzger C,Gonzalez-Figueroa P,Canete PF,Ellyard J,Shen Q,Robert PA,Cappello J,Vohra H,Zhang Y,Nowosad CR,Schiepers A,Corcoran LM,Toellner KM,Polo JM,Meyer-Hermann M,Victora GD,Vinuesa CG
Tue Aug 20 00:00:00 EDT 2019
Distinguishing naive- from memory-derived human B cells during acute responses.
Clinical & translational immunology
Auladell M,Nguyen TH,Garcillán B,Mackay F,Kedzierska K,Fox A
Mon Apr 11 00:00:00 EDT 2022
Compromised functionality of monocyte-derived dendritic cells in multiple myeloma patients may limit their use in cancer immunotherapy.
Scientific reports
Shinde P,Fernandes S,Melinkeri S,Kale V,Limaye L
Mon Apr 09 00:00:00 EDT 2018
B cell-derived IL-6 initiates spontaneous germinal center formation during systemic autoimmunity.
The Journal of experimental medicine
Arkatkar T,Du SW,Jacobs HM,Dam EM,Hou B,Buckner JH,Rawlings DJ,Jackson SW
Mon Nov 06 00:00:00 EST 2017
B Cell-Intrinsic Role for IRF5 in TLR9/BCR-Induced Human B Cell Activation, Proliferation, and Plasmablast Differentiation.
Frontiers in immunology
De S,Zhang B,Shih T,Singh S,Winkler A,Donnelly R,Barnes BJ
310-02 was used in Cell Culture to identify IRF5 as an early regulator of human B cell activation and map IRF5 dysfunction in systemic lupus erythematosus.
Fri Sep 18 00:00:00 EDT 2020
Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia.
Scientific reports
Carabia J,Carpio C,Abrisqueta P,Jiménez I,Purroy N,Calpe E,Palacio C,Bosch F,Crespo M
Mon Sep 25 00:00:00 EDT 2017
IL-4 rescues surface IgM expression in chronic lymphocytic leukemia.
Blood
Guo B,Zhang L,Chiorazzi N,Rothstein TL
Thu Jul 28 00:00:00 EDT 2016
B cell IFN-γ receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6.
The Journal of experimental medicine
Jackson SW,Jacobs HM,Arkatkar T,Dam EM,Scharping NE,Kolhatkar NS,Hou B,Buckner JH,Rawlings DJ
Mon May 02 00:00:00 EDT 2016
Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation.
Proceedings of the National Academy of Sciences of the United States of America
Brook M,Tomlinson GH,Miles K,Smith RW,Rossi AG,Hiemstra PS,van 't Wout EF,Dean JL,Gray NK,Lu W,Gray M
Tue Apr 19 00:00:00 EDT 2016
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
Thu May 07 00:00:00 EDT 2015
Allogeneic IgG combined with dendritic cell stimuli induce antitumour T-cell immunity.
Nature
Carmi Y,Spitzer MH,Linde IL,Burt BM,Prestwood TR,Perlman N,Davidson MG,Kenkel JA,Segal E,Pusapati GV,Bhattacharya N,Engleman EG
Thu May 07 00:00:00 EDT 2015
Differential induction of plasma cells by isoforms of human TACI.
Blood
Garcia-Carmona Y,Cols M,Ting AT,Radigan L,Yuk FJ,Zhang L,Cerutti A,Cunningham-Rundles C
Thu Mar 12 00:00:00 EDT 2015
CD32a antibodies induce thrombocytopenia and type II hypersensitivity reactions in FCGR2A mice.
Blood
Meyer T,Robles-Carrillo L,Davila M,Brodie M,Desai H,Rivera-Amaya M,Francis JL,Amirkhosravi A
Thu Nov 05 00:00:00 EST 2015
Involvement of the HCK and FGR src-family kinases in FCRL4-mediated immune regulation.
Journal of immunology (Baltimore, Md. : 1950)
Liu Y,Bezverbnaya K,Zhao T,Parsons MJ,Shi M,Treanor B,Ehrhardt GR
Mon Jun 15 00:00:00 EDT 2015
CD40 ligand induces RIP1-dependent, necroptosis-like cell death in low-grade serous but not serous borderline ovarian tumor cells.
Cell death & disease
Qiu X,Klausen C,Cheng JC,Leung PC
Thu Aug 27 00:00:00 EDT 2015
Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy.
Blood
Woyach JA,Smucker K,Smith LL,Lozanski A,Zhong Y,Ruppert AS,Lucas D,Williams K,Zhao W,Rassenti L,Ghia E,Kipps TJ,Mantel R,Jones J,Flynn J,Maddocks K,O'Brien S,Furman RR,James DF,Clow F,Lozanski G,Johnson AJ,Byrd JC
Thu Mar 20 00:00:00 EDT 2014
Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia.
Journal of immunology (Baltimore, Md. : 1950)
Gordon SN,Doster MN,Kines RC,Keele BF,Brocca-Cofano E,Guan Y,Pegu P,Liyanage NP,Vaccari M,Cuburu N,Buck CB,Ferrari G,Montefiori D,Piatak M,Lifson JD,Xenophontos AM,Venzon D,Robert-Guroff M,Graham BS,Lowy DR,Schiller JT,Franchini G
Mon Dec 15 00:00:00 EST 2014
CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia.
Blood
Fedorchenko O,Stiefelhagen M,Peer-Zada AA,Barthel R,Mayer P,Eckei L,Breuer A,Crispatzu G,Rosen N,Landwehr T,Lilienthal N,Möllmann M,Montesinos-Rongen M,Heukamp L,Dürig J,Hallek M,Fingerle-Rowson G,Herling M
Thu May 16 00:00:00 EDT 2013
Dendritic cell reprogramming by endogenously produced lactic acid.
Journal of immunology (Baltimore, Md. : 1950)
Nasi A,Fekete T,Krishnamurthy A,Snowden S,Rajnavölgyi E,Catrina AI,Wheelock CE,Vivar N,Rethi B
Sun Sep 15 00:00:00 EDT 2013
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
An NKp30-based chimeric antigen receptor promotes T cell effector functions and antitumor efficacy in vivo.
Journal of immunology (Baltimore, Md. : 1950)
Zhang T,Wu MR,Sentman CL
Sat Sep 01 00:00:00 EDT 2012
Differential expression of neurotensin and specific receptors, NTSR1 and NTSR2, in normal and malignant human B lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Saada S,Marget P,Fauchais AL,Lise MC,Chemin G,Sindou P,Martel C,Delpy L,Vidal E,Jaccard A,Troutaud D,Lalloué F,Jauberteau MO
Sat Dec 01 00:00:00 EST 2012
NADPH oxidase is internalized by clathrin-coated pits and localizes to a Rab27A/B GTPase-regulated secretory compartment in activated macrophages.
The Journal of biological chemistry
Ejlerskov P,Christensen DP,Beyaie D,Burritt JB,Paclet MH,Gorlach A,van Deurs B,Vilhardt F
Fri Feb 10 00:00:00 EST 2012
Phospho-specific flow cytometry identifies aberrant signaling in indolent B-cell lymphoma.
BMC cancer
Blix ES,Irish JM,Husebekk A,Delabie J,Forfang L,Tierens AM,Myklebust JH,Kolstad A
Tue Oct 16 00:00:00 EDT 2012
Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.
Blood
Herman SE,Gordon AL,Hertlein E,Ramanunni A,Zhang X,Jaglowski S,Flynn J,Jones J,Blum KA,Buggy JJ,Hamdy A,Johnson AJ,Byrd JC
Thu Jun 09 00:00:00 EDT 2011
Contribution of surface localization to platelet activation by CD154 antibodies and introduction of a novel approach for studying immune complex activity.
Thrombosis research
Hatfield M,Meyer T,Meyer J,Robles-Carrillo L,Francis JL,Amirkhosravi A
Wed Jun 01 00:00:00 EDT 2011
Aberrant expression of functional BAFF-system receptors by malignant B-cell precursors impacts leukemia cell survival.
PloS one
Maia S,Pelletier M,Ding J,Hsu YM,Sallan SE,Rao SP,Nadler LM,Cardoso AA
Fri Oct 14 00:00:00 EDT 2011
Milatuzumab immunoliposomes induce cell death in CLL by promoting accumulation of CD74 on the surface of B cells.
Blood
Hertlein E,Triantafillou G,Sass EJ,Hessler JD,Zhang X,Jarjoura D,Lucas DM,Muthusamy N,Goldenberg DM,Lee RJ,Byrd JC
Thu Oct 07 00:00:00 EDT 2010
Phosphatidylinositol 3-kinase-δ inhibitor CAL-101 shows promising preclinical activity in chronic lymphocytic leukemia by antagonizing intrinsic and extrinsic cellular survival signals.
Blood
Herman SE,Gordon AL,Wagner AJ,Heerema NA,Zhao W,Flynn JM,Jones J,Andritsos L,Puri KD,Lannutti BJ,Giese NA,Zhang X,Wei L,Byrd JC,Johnson AJ
Thu Sep 23 00:00:00 EDT 2010
Soluble HIV-1 Env trimers in adjuvant elicit potent and diverse functional B cell responses in primates.
The Journal of experimental medicine
Sundling C,Forsell MN,O'Dell S,Feng Y,Chakrabarti B,Rao SS,Loré K,Mascola JR,Wyatt RT,Douagi I,Karlsson Hedestam GB
Mon Aug 30 00:00:00 EDT 2010
Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients.
Proceedings of the National Academy of Sciences of the United States of America
Nuber N,Curioni-Fontecedro A,Matter C,Soldini D,Tiercy JM,von Boehmer L,Moch H,Dummer R,Knuth A,van den Broek M
Tue Aug 24 00:00:00 EDT 2010
Anti-CD40L immune complexes potently activate platelets in vitro and cause thrombosis in FCGR2A transgenic mice.
Journal of immunology (Baltimore, Md. : 1950)
Robles-Carrillo L,Meyer T,Hatfield M,Desai H,Dávila M,Langer F,Amaya M,Garber E,Francis JL,Hsu YM,Amirkhosravi A
Sun Aug 01 00:00:00 EDT 2010
High TCL1 levels are a marker of B-cell receptor pathway responsiveness and adverse outcome in chronic lymphocytic leukemia.
Blood
Herling M,Patel KA,Weit N,Lilienthal N,Hallek M,Keating MJ,Jones D
Thu Nov 19 00:00:00 EST 2009
BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells.
Blood
Fu L,Lin-Lee YC,Pham LV,Tamayo AT,Yoshimura LC,Ford RJ
Thu May 07 00:00:00 EDT 2009
Different proliferative and survival capacity of CLL-cells in a newly established in vitro model for pseudofollicles.
Leukemia
Plander M,Seegers S,Ugocsai P,Diermeier-Daucher S,Iványi J,Schmitz G,Hofstädter F,Schwarz S,Orsó E,Knüchel R,Brockhoff G
Sun Nov 01 00:00:00 EDT 2009
Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins.
Journal of immunology (Baltimore, Md. : 1950)
Miles K,Clarke DJ,Lu W,Sibinska Z,Beaumont PE,Davidson DJ,Barr TA,Campopiano DJ,Gray M
Sat Aug 01 00:00:00 EDT 2009
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.
Nature immunology
Vallabhapurapu S,Matsuzawa A,Zhang W,Tseng PH,Keats JJ,Wang H,Vignali DA,Bergsagel PL,Karin M
Mon Dec 01 00:00:00 EST 2008
Cellular basis of the role of diesel exhaust particles in inducing Th2-dominant response.
Journal of immunology (Baltimore, Md. : 1950)
Ohtani T,Nakagawa S,Kurosawa M,Mizuashi M,Ozawa M,Aiba S
Tue Feb 15 00:00:00 EST 2005
