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Product Details
RP-89568
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
KFMSLQPSISVSEMEPNGTFSNNNSRNCTIE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (35%), Rat (35%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CysLT(2); CysLT-2; CysLTR2; cysteinyl leukotriene CysLT2 receptor; Cysteinyl leukotriene receptor 2; G-protein coupled receptor GPCR21; G-protein coupled receptor HG57; hGPCR21; HPN321
Gene Aliases: CYSLT2; CYSLT2R; CYSLTR2; GPCR21; HG57; hGPCR21; HPN321; KPG_011; PSEC0146
UniProt ID: (Human) Q9NS75
Entrez Gene ID: (Human) 57105
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