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Product Details
RP-105601
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
YDNLPHYNSWIKVLYDFVMDDTISPYSRMKRHQKGEMVLE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-85000. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cell migration-inducing gene 15 protein; Degenerative spermatocyte homolog 1; degenerative spermatocyte homolog 1, lipid desaturase; degenerative spermatocyte homolog, lipid desaturase; Delta(4)-desaturase; delta(4)-desaturase, sphingolipid 1; dihydroceramide desaturase 1; Dihydroceramide desaturase-1; DSH1; membrane fatty acid (lipid) desaturase; Membrane lipid desaturase; MGC5079; migration-inducing gene 15 protein; Retinol isomerase; sphingolipid 1; sphingolipid delta 4 desaturase; sphingolipid delta(4)-desaturase 1; Sphingolipid delta(4)-desaturase DES1
Gene Aliases: DEGS; DEGS-1; DEGS1; Des-1; DES1; FADS7; MIG15; MLD
UniProt ID: (Human) O15121
Entrez Gene ID: (Human) 8560
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