Product References
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution.
Cell reports methods
Conforti P,Bocchi VD,Campus I,Scaramuzza L,Galimberti M,Lischetti T,Talpo F,Pedrazzoli M,Murgia A,Ferrari I,Cordiglieri C,Fasciani A,Arenas E,Felsenfeld D,Biella G,Besusso D,Cattaneo E
120-30 was used in Cell Culture to develop an efficient method to generate D1 and D2-medium spiny neurons (MSNs) from hESC, which eventually could facilitate cell-replacement therapies for Huntington’s disease (HD).
Mon Dec 19 00:00:00 EST 2022
Epithelial cell plasticity drives endoderm formation during gastrulation.
Nature cell biology
Scheibner K,Schirge S,Burtscher I,Büttner M,Sterr M,Yang D,Böttcher A,Irmler M,Beckers J,Cernilogar FM,Schotta G,Theis FJ,Lickert H
Thu Jul 01 00:00:00 EDT 2021
Long-term effects of human induced pluripotent stem cell-derived retinal cell transplantation in Pde6b knockout rats.
Experimental & molecular medicine
Yang JM,Chung S,Yun K,Kim B,So S,Kang S,Kang E,Lee JY
Thu Apr 01 00:00:00 EDT 2021
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease.
Nature communications
Hu D,Sun X,Magpusao A,Fedorov Y,Thompson M,Wang B,Lundberg K,Adams DJ,Qi X
Mon Sep 06 00:00:00 EDT 2021
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis.
Nature
Nikolaev M,Mitrofanova O,Broguiere N,Geraldo S,Dutta D,Tabata Y,Elci B,Brandenberg N,Kolotuev I,Gjorevski N,Clevers H,Lutolf MP
Tue Sep 01 00:00:00 EDT 2020
DKK1 Induced by 1,25D3 Is Required for the Mineralization of Osteoblasts.
Cells
Jo S,Yoon S,Lee SY,Kim SY,Park H,Han J,Choi SH,Han JS,Yang JH,Kim TH
120-30 was used in Cell Culture to investigate DKK1 in osteoporosis treatment by 1,25D3.
Fri Jan 17 00:00:00 EST 2020
Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in the Subretinal Space of the Cat Eye.
Stem cells and development
Singh RK,Occelli LM,Binette F,Petersen-Jones SM,Nasonkin IO
Sun Sep 01 00:00:00 EDT 2019
Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells.
Scientific reports
Pettinato G,Lehoux S,Ramanathan R,Salem MM,He LX,Muse O,Flaumenhaft R,Thompson MT,Rouse EA,Cummings RD,Wen X,Fisher RA
Thu Jun 20 00:00:00 EDT 2019
COL4A2 in the tissue-specific extracellular matrix plays important role on osteogenic differentiation of periodontal ligament stem cells.
Theranostics
Wen Y,Yang H,Wu J,Wang A,Chen X,Hu S,Zhang Y,Bai D,Jin Z
120-30 was used in Sample Preparation (Western Blotting) to study whether different extracellular matrices (ECMs) exert diverse effects on osteogenic differentiation of periodontal ligament stem cells (PDLSCs) to show that Type IV collagen A2 (COL4A2) in the ECM promotes osteogenic differentiation of PDLSCs through negative regulation of the Wnt/β-catenin pathway.
Mon Jul 06 00:00:00 EDT 2020
Inhibition of Tet1- and Tet2-mediated DNA demethylation promotes immunomodulation of periodontal ligament stem cells.
Cell death & disease
Yu T,Liu D,Zhang T,Zhou Y,Shi S,Yang R
Mon Oct 14 00:00:00 EDT 2019
ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma.
Cell death & disease
Wu YJ,Ko BS,Liang SM,Lu YJ,Jan YJ,Jiang SS,Shyue SK,Chen L,Liou JY
Tue May 28 00:00:00 EDT 2019
ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Nature communications
Zhao Y,Sun X,Hu D,Prosdocimo DA,Hoppel C,Jain MK,Ramachandran R,Qi X
Tue Mar 26 00:00:00 EDT 2019
Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.
Cell
Fiddes IT,Lodewijk GA,Mooring M,Bosworth CM,Ewing AD,Mantalas GL,Novak AM,van den Bout A,Bishara A,Rosenkrantz JL,Lorig-Roach R,Field AR,Haeussler M,Russo L,Bhaduri A,Nowakowski TJ,Pollen AA,Dougherty ML,Nuttle X,Addor MC,Zwolinski S,Katzman S,Kriegstein A,Eichler EE,Salama SR,Jacobs FMJ,Haussler D
Thu May 31 00:00:00 EDT 2018
Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer.
The Journal of experimental medicine
Shee K,Yang W,Hinds JW,Hampsch RA,Varn FS,Traphagen NA,Patel K,Cheng C,Jenkins NP,Kettenbach AN,Demidenko E,Owens P,Faber AC,Golub TR,Straussman R,Miller TW
Mon Mar 05 00:00:00 EST 2018
Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.
Proceedings of the National Academy of Sciences of the United States of America
Conforti P,Besusso D,Bocchi VD,Faedo A,Cesana E,Rossetti G,Ranzani V,Svendsen CN,Thompson LM,Toselli M,Biella G,Pagani M,Cattaneo E
Tue Jan 23 00:00:00 EST 2018
Single cell RNA sequencing of stem cell-derived retinal ganglion cells.
Scientific data
Daniszewski M,Senabouth A,Nguyen QH,Crombie DE,Lukowski SW,Kulkarni T,Sluch VM,Jabbari JS,Chamling X,Zack DJ,Pébay A,Powell JE,Hewitt AW
Tue Feb 13 00:00:00 EST 2018
Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells.
Stem cell reports
Kauts ML,De Leo B,Rodríguez-Seoane C,Ronn R,Glykofrydis F,Maglitto A,Kaimakis P,Basi M,Taylor H,Forrester L,Wilkinson AC,Göttgens B,Saunders P,Dzierzak E
Tue Oct 09 00:00:00 EDT 2018
Knockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway.
Cell death & disease
Chen EEM,Zhang W,Ye CCY,Gao X,Jiang LLJ,Zhao TTF,Pan ZZJ,Xue DDT
Thu Sep 07 00:00:00 EDT 2017
VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease.
Nature communications
Guo X,Sun X,Hu D,Wang YJ,Fujioka H,Vyas R,Chakrapani S,Joshi AU,Luo Y,Mochly-Rosen D,Qi X
Fri Aug 26 00:00:00 EDT 2016
Long noncoding RNA related to periodontitis interacts with miR-182 to upregulate osteogenic differentiation in periodontal mesenchymal stem cells of periodontitis patients.
Cell death & disease
Wang L,Wu F,Song Y,Li X,Wu Q,Duan Y,Jin Z
Thu Aug 11 00:00:00 EDT 2016
Enriched retinal ganglion cells derived from human embryonic stem cells.
Scientific reports
Gill KP,Hung SS,Sharov A,Lo CY,Needham K,Lidgerwood GE,Jackson S,Crombie DE,Nayagam BA,Cook AL,Hewitt AW,Pébay A,Wong RC
Wed Aug 10 00:00:00 EDT 2016
Overexpression of HSPA1A enhances the osteogenic differentiation of bone marrow mesenchymal stem cells via activation of the Wnt/β-catenin signaling pathway.
Scientific reports
Zhang W,Xue D,Yin H,Wang S,Li C,Chen E,Hu D,Tao Y,Yu J,Zheng Q,Gao X,Pan Z
Thu Jun 09 00:00:00 EDT 2016
Role of Wnt/β-catenin and RANKL/OPG in bone healing of diabetic Charcot arthropathy patients.
Acta orthopaedica
Folestad A,Ålund M,Asteberg S,Fowelin J,Aurell Y,Göthlin J,Cassuto J
120-30 was used in In vitro experiments to investigate pathogenic mechanisms of charcot neuropathy.
Mon Nov 09 00:00:00 EST 2015
2,4,5-Trimethoxyldalbergiquinol promotes osteoblastic differentiation and mineralization via the BMP and Wnt/β-catenin pathway.
Cell death & disease
Yun HM,Park KR,Quang TH,Oh H,Hong JT,Kim YC,Kim EC
Thu Jul 16 00:00:00 EDT 2015
Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature.
Scientific reports
Ng TK,Yung JS,Choy KW,Cao D,Leung CK,Cheung HS,Pang CP
Mon Nov 09 00:00:00 EST 2015
MiR-26a functions oppositely in osteogenic differentiation of BMSCs and ADSCs depending on distinct activation and roles of Wnt and BMP signaling pathway.
Cell death & disease
Su X,Liao L,Shuai Y,Jing H,Liu S,Zhou H,Liu Y,Jin Y
Thu Aug 06 00:00:00 EDT 2015
Dickkopf-related protein 1 inhibits the WNT signaling pathway and improves pig oocyte maturation.
PloS one
Spate LD,Brown AN,Redel BK,Whitworth KM,Murphy CN,Prather RS
120-30 was used in Sample Preparation (PCR) to demonstarte the significance of WNT signaling pathway, supllemented by Dickkopf-related protein 1, for proper maturation of oocytes in vitro.
Mon Jun 01 00:00:00 EDT 2015
Dickkopf-related protein 1 inhibits the WNT signaling pathway and improves pig oocyte maturation.
PloS one
Spate LD,Brown AN,Redel BK,Whitworth KM,Murphy CN,Prather RS
120-30 was used in Sample Preparation (PCR) to demonstarte the significance of WNT signaling pathway, supllemented by Dickkopf-related protein 1, for proper maturation of oocytes in vitro.
Mon Jun 01 00:00:00 EDT 2015
Lmx1a allows context-specific isolation of progenitors of GABAergic or dopaminergic neurons during neural differentiation of embryonic stem cells.
Stem cells (Dayton, Ohio)
Nefzger CM,Su CT,Fabb SA,Hartley BJ,Beh SJ,Zeng WR,Haynes JM,Pouton CW
Sun Jul 01 00:00:00 EDT 2012
Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection.
The Journal of biological chemistry
Chuang CY,Lin KI,Hsiao M,Stone L,Chen HF,Huang YH,Lin SP,Ho HN,Kuo HC
Fri Apr 27 00:00:00 EDT 2012
Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells.
Stem cells (Dayton, Ohio)
Sharon N,Mor I,Golan-lev T,Fainsod A,Benvenisty N
Fri Apr 01 00:00:00 EDT 2011
Small-molecule induction of neural crest-like cells derived from human neural progenitors.
Stem cells (Dayton, Ohio)
Hotta R,Pepdjonovic L,Anderson RB,Zhang D,Bergner AJ,Leung J,Pébay A,Young HM,Newgreen DF,Dottori M
Tue Dec 01 00:00:00 EST 2009
