Gibco

Human EG-VEGF Recombinant Protein, PeproTech®

Product Details

100-44-20UG

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

ELISA (ELISA)

Assay-dependent

View 1 publication 1 publication

Functional Assay (Functional)

Assay-dependent

In vitro Assay (IV)

View 7 publications 7 publications

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Product Specifications

Species

Human

Published species

Human, Mouse, Pig

Expression System

E. coli

Amino acid sequence

AVITGACERD VQCGAGTCCA ISLWLRGLRM CTPLGREGEE CHPGSHKVPF FRKRKHHTCP CLPNLLCSRF PDGRYRCSMD LKNINF

Molecular weight

9.6 kDa

Class

Recombinant

Type

Protein

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Human EG-VEGF is a 9.6 kDa protein consisting of 86 amino acid residues, including ten cysteine residues that potentially form five pairs of intra-molecular disulfide bonds.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

Endocrine gland-derived vascular endothelial growth factor induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. Its expression is induced by hypoxia and is restricted to the steroidogenic glands. Its expression is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia.

Developmental cell

Ma Y,Liu S,Gao J,Chen C,Zhang X,Yuan H,Chen Z,Yin X,Sun C,Mao Y,Zhou F,Shao Y,Liu Q,Xu J,Cheng L,Yu D,Li P,Yi P,He J,Geng G,Guo Q,Si Y,Zhao H,Li H,Banes GL,Liu H,Nakamura Y,Kurita R,Huang Y,Wang X,Wang F,Fang G,Engel JD,Shi L,Zhang YE,Yu J

100-44 was used in Sample Preparation (FC/FACS) to investigate pseudogene phenotypic effects.

Mon Feb 22 00:00:00 EST 2021

Reciprocal Antagonism between MicroRNA-138 and SIRT1 and Its Implications for the Angiogenesis of Endothelial Cells.

Journal of vascular research

Wang S,Shao Z,Tang X,Wang K,Zhao J,Dong Z

100-44 was used in Cell Culture to investigate the interactions between miR-138 and sirtuins in the process of angiogenesis.

Wed Feb 03 00:00:00 EST 2021

Prokineticin 1-prokineticin receptor 1 signaling in trophoblast promotes embryo implantation and placenta development.

Scientific reports

Goryszewska-Szczurek E,Baryla M,Kaczynski P,Waclawik A

Fri Jul 02 00:00:00 EDT 2021

Dihydrotestosterone potentiates insulin to up-regulate prokineticin-1 in decidualizing human endometrial stromal cells.

Journal of cellular and molecular medicine

Ujvari D,Graells Brugalla C,Hirschberg AL

Sun Mar 01 00:00:00 EST 2020

CTGF expression is up-regulated by PROK1 in early pregnancy and influences HTR-8/Svneo cell adhesion and network formation.

Human reproduction (Oxford, England)

Waddell JM,Evans J,Jabbour HN,Denison FC

Sat Jan 01 00:00:00 EST 2011

Prokineticin 1 induces inflammatory response in human myometrium: a potential role in initiating term and preterm parturition.

The American journal of pathology

Gorowiec MR,Catalano RD,Norman JE,Denison FC,Jabbour HN

Thu Dec 01 00:00:00 EST 2011

Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.

The Journal of biological chemistry

Xu D,Fuster MM,Lawrence R,Esko JD

100-44 was used in In vivo experiments to demonstrate how VEGF-induced vascular hyper-permeability depends on endothelial heparan sulfate.

Fri Jan 07 00:00:00 EST 2011

Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway.

Molecular human reproduction

Cook IH,Evans J,Maldonado-Pérez D,Critchley HO,Sales KJ,Jabbour HN

Mon Mar 01 00:00:00 EST 2010

Prokineticin-1: a novel mediator of the inflammatory response in third-trimester human placenta.

Endocrinology

Denison FC,Battersby S,King AE,Szuber M,Jabbour HN

Tue Jul 01 00:00:00 EDT 2008

Implications of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 signaling in human neuroblastoma progression.

Clinical cancer research : an official journal of the American Association for Cancer Research

Ngan ES,Sit FY,Lee K,Miao X,Yuan Z,Wang W,Nicholls JM,Wong KK,Garcia-Barcelo M,Lui VC,Tam PK

Thu Feb 01 00:00:00 EST 2007

Bioinformatics

Protein Aliases: black mamba toxin-related protein; EG-VEGF; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; Prokineticin-1

Human EG-VEGF Recombinant Protein, PeproTech®

Product Details

100-44-20UG

Western Blot (WB)

ELISA (ELISA)

Functional Assay (Functional)

In vitro Assay (IV)

Miscellaneous PubMed (Misc)

Species

Published species

Expression System

Amino acid sequence

Molecular weight

Class

Type

Purity

Endotoxin concentration

Conjugate

Form

Purification

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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