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Product Details
RP-90848
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
MVEAFCATWKLTNSQNFDEYMKALGVGFATRQVGNVTKPTVIISQEGDKVVIRTLSTFKNTEISFQLGEEFDETTADDRNCK
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-83034. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B FABP; B-FABP; BLBP; Brain lipid-binding protein; Brain-type fatty acid-binding protein; DKFZp547J2313; FABP 7; Fatty acid-binding protein 7; Fatty acid-binding protein, brain; hypothetical protein DKFZp547J2313; Mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; OTTHUMP00000017119; RP11-548E19.1
Gene Aliases: B-FABP; BLBP; FABP7; FABPB; MRG
UniProt ID: (Human) O15540
Entrez Gene ID: (Human) 2173
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