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Product Details
RP-100269
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
WDSGFSEVSGSTWREEELPVSQRPAPSAQPLRRQCLSVSGLPMPSRAPVASVPPVHHPRPKSTPDACLEHWQGLEAEDWTAALLNRGRS
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59769. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
FAM212A, initially identified as INCA (induced in neural crest by AP-2alpha) in xenopus, is expressed primarily in neural crest cells and their derivatives. FAM212A can associate with the P21-kinase protein PAK4 and this association modulates cytoskeletal dynamics. In mammals, FAM212A is thought to play a role in neural tube closure; a significant fraction of FAM212A-null mice exhibited exencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 212, member A; INCA; Induced in neural crest by AP2-alpha protein homolog; Inka-box actin regulator 1; PAK4-inhibitor INKA1
Gene Aliases: C3orf54; FAM212A; INKA1
UniProt ID: (Human) Q96EL1
Entrez Gene ID: (Human) 389119
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