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Invitrogen
Human FAM3C (aa 112-186) Control Fragment Recombinant Protein
Product Details
RP-100292
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
KTGEVLDTKYFDMWGGDVAPFIEFLKAIQDGTIVLMGTYDDGATKLNDEARRLIADLGSTSITNLGFRDNWVFCG
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84014. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
FAM3C is a 227 amino acid secretory protein that belongs to a novel cytokine-like family with sequence similarity to FAM3 family. FAM3C is a signaling cytokine with a GG domain, hydrophobic leader sequence and an N-terminal signal peptide. FAM3C has a cytokine activity and shows a change in expression in pancreatic cancer-derived cells. It is ubiquitously expressed in most of the tissues. Reports suggest that FAM3C plays an important role in inner ear development and may thus be involved in cell differentiation and proliferation during inner ear embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: family with sequence similarity 3, member C; Interleukin-like EMT inducer; interleukin-like epithelial-mesenchymal transition inducer; predicted osteoblast protein; Protein FAM3C
Gene Aliases: FAM3C; GS3786; ILEI
UniProt ID: (Human) Q92520
Entrez Gene ID: (Human) 10447
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