Product References
Regulation of CTCF loop formation during pancreatic cell differentiation.
Nature communications
Lyu X,Rowley MJ,Kulik MJ,Dalton S,Corces VG
AF-100-19 was used in In vitro experiments to suggest an important role for CTCF and cohesin in controlling gene expression during cell differentiation.
Mon Oct 09 00:00:00 EDT 2023
Generation of insulin-producing pancreatic β cells from multiple human stem cell lines.
Nature protocols
Hogrebe NJ,Maxwell KG,Augsornworawat P,Millman JR
Wed Sep 01 00:00:00 EDT 2021
LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells.
Stem cell research & therapy
He F,Li N,Huang HB,Wang JB,Yang XF,Wang HD,Huang W,Li FR
AF-100-19 was used in Cell Culture to investigate the role of LSD1 on insulin production from human embryonic stem cell line H9.
Tue Apr 28 00:00:00 EDT 2020
A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells.
Acta biomaterialia
Augsornworawat P,Velazco-Cruz L,Song J,Millman JR
AF-100-19 was used in In vitro experiments to produce a strategy of assembling human embryonic stem cell-derived islet cells with endothelial cells into three-dimensional aggregates on a hydrogel for the assembly of endothelial cells with SC-β and other endocrine cells, producing islet organoids that are functional and express β cell markers, that can be used to study the islet microenvironment and islet tissue engineering.
Tue Oct 01 00:00:00 EDT 2019
FGFR2 Promotes Expression of PD-L1 in Colorectal Cancer via the JAK/STAT3 Signaling Pathway.
Journal of immunology (Baltimore, Md. : 1950)
Li P,Huang T,Zou Q,Liu D,Wang Y,Tan X,Wei Y,Qiu H
AF-100-19 was used in Cell Culture to study the regulation of programmed cell death ligand 1 (PD-L1) expression in colorectal cancer (CRC) to reveal a novel mechanism of PD-L1 expression in CRC, thus providing a theoretical basis for reversing the immune tolerance of FGFR2 overexpression in CRC.
Wed May 15 00:00:00 EDT 2019
Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic.
Stem cell reports
Rezanejad H,Ouziel-Yahalom L,Keyzer CA,Sullivan BA,Hollister-Lock J,Li WC,Guo L,Deng S,Lei J,Markmann J,Bonner-Weir S
Tue Mar 13 00:00:00 EDT 2018
Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents.
PloS one
Southard SM,Kotipatruni RP,Rust WL
AF-100-19 was used in Cell Culture to show that SR1423 is a candidate cell line for the production of insulin-producing cells useful for the treatment of diabetes.
Thu Feb 21 00:00:00 EST 2019
Economic 3D-printing approach for transplantation of human stem cell-derived β-like cells.
Biofabrication
Song J,Millman JR
AF-100-19 was used in In vitro experiments to present a multifaceted transplantation strategy that combines differentiation into stem cell-derived β (SC-β) cells with 3D printing which serves as a platform for future transplantation strategies.
Thu Dec 01 00:00:00 EST 2016
Mutant surfactant A2 proteins associated with familial pulmonary fibrosis and lung cancer induce TGF-β1 secretion.
Proceedings of the National Academy of Sciences of the United States of America
Maitra M,Cano CA,Garcia CK
Tue Dec 18 00:00:00 EST 2012
Axin pathway activity regulates in vivo pY654-β-catenin accumulation and pulmonary fibrosis.
The Journal of biological chemistry
Ulsamer A,Wei Y,Kim KK,Tan K,Wheeler S,Xi Y,Thies RS,Chapman HA
Fri Feb 10 00:00:00 EST 2012
Fibroblast growth factor 22 is not essential for skin development and repair but plays a role in tumorigenesis.
PloS one
Jarosz M,Robbez-Masson L,Chioni AM,Cross B,Rosewell I,Grose R
Fri Dec 14 00:00:00 EST 2012
A novel solid-phase site-specific PEGylation enhances the in vitro and in vivo biostabilty of recombinant human keratinocyte growth factor 1.
PloS one
Huang Z,Zhu G,Sun C,Zhang J,Zhang Y,Zhang Y,Ye C,Wang X,Ilghari D,Li X
Mon Sep 10 00:00:00 EDT 2012
Nuclear translocation of β-catenin during mesenchymal stem cells differentiation into hepatocytes is associated with a tumoral phenotype.
PloS one
Herencia C,Martínez-Moreno JM,Herrera C,Corrales F,Santiago-Mora R,Espejo I,Barco M,Almadén Y,de la Mata M,Rodríguez-Ariza A,Muñoz-Castañeda JR
Wed Oct 17 00:00:00 EDT 2012
Isolation of alveolar epithelial type II progenitor cells from adult human lungs.
Laboratory investigation; a journal of technical methods and pathology
Fujino N,Kubo H,Suzuki T,Ota C,Hegab AE,He M,Suzuki S,Suzuki T,Yamada M,Kondo T,Kato H,Yamaya M
Tue Mar 01 00:00:00 EST 2011
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.
Cell research
Song Z,Cai J,Liu Y,Zhao D,Yong J,Duo S,Song X,Guo Y,Zhao Y,Qin H,Yin X,Wu C,Che J,Lu S,Ding M,Deng H
Sun Nov 01 00:00:00 EDT 2009