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Invitrogen
Human GABRG1 (aa 19-68) Control Fragment Recombinant Protein
Product Details
RP-96574
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
RGVRLVFLLLTLHLGNCVDKADDEDDEDLTVNKTWVLAPKIHEGDITQIL
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57340. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Gabrg1 encodes a protein that belongs to the ligand-gated ionic channel family. Gabrg1 is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. The Gabrg1 gene is clustered with three other family members on chromosome 4. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, are responsible for mediating the inhibitory effects of GABA. Structurally, Gabrg1 are pentameric proteins, consisting of five subunits belonging to different families. Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GABA(A) receptor subunit gamma-1; GABA(A) receptor, gamma; GABAAR gamma1; GABAAR subunit gamma-1; Gabeg1; gamma-1 polypeptide; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) A receptor, gamma 1; Gamma-aminobutyric acid receptor subunit gamma-1
Gene Aliases: GABRG1
UniProt ID: (Human) Q8N1C3
Entrez Gene ID: (Human) 2565
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