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Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111645. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) protein, also known as GDE2, is a seven transmembrane, widely expressed protein that is necessary for spinal motor neuron differentiation and retinoid-induced neuronal outgrowth. Altered choline phospholipid metabolism is a hallmark of cancer, and the elevated expression of GDPD5 correlates with malignant choline phospholipid metabolite profiles in human breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glycerophosphocholine phosphodiesterase GDPD5; Glycerophosphodiester phosphodiesterase 2; Glycerophosphodiester phosphodiesterase domain-containing protein 5; Phosphoinositide phospholipase C GDPD5
Gene Aliases: GDE2; GDPD5; PP1665; PP6037; PP9363; UNQ1850/PRO3580
UniProt ID: (Human) Q8WTR4
Entrez Gene ID: (Human) 81544
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