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Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59194. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D-glucuronyl C5-epimerase; glucuronyl C5-epimerase; Heparan sulfate C5-epimerase; heparan sulfate epimerase; heparin/heparan sulfate-glucuronic acid C5-epimerase; Heparin/heparan sulfate:glucuronic acid C5-epimerase; Heparosan-N-sulfate-glucuronate 5-epimerase; Hsepi; UDP-glucuronic acid epimerase
Gene Aliases: GLCE; HSEPI; KIAA0836
UniProt ID: (Human) O94923
Entrez Gene ID: (Human) 26035
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