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Product Details
RP-107998
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
LSVNRSSASSSHFGAVGESSRAFPAPAQEPRFRQAASSCSLSSPESLPCT
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111718. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxB5 (homeobox protein Hox-B5), also known as HOX2, HU-1, HOX2A, Hox2.1 or HHO.C10, is a member of the Antp homeobox (Hox) family. It is a 269 amino acid long nuclear protein expressed in the central nervous system. HoxB5 contains one homeobox DNAbinding domain and plays a role in the regulation of lung and gut development, providing cells with positional identities on the anterior-posterior body axis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homeo box 2A; homeo box B5; Homeobox protein HHO.C10; Homeobox protein Hox-2A; Homeobox protein Hox-B5; Homeobox protein Hu-1
Gene Aliases: HHO.C10; HOX2; Hox2.1; HOX2A; HOXB5; HU-1
UniProt ID: (Human) P09067
Entrez Gene ID: (Human) 3215
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