Product References
Pyridoxamine ameliorates methylglyoxal-induced macrophage dysfunction to facilitate tissue repair in diabetic wounds.
International wound journal
Jiang M,Yakupu A,Guan H,Dong J,Liu Y,Song F,Tang J,Tian M,Niu Y,Lu S
Sat Jan 01 00:00:00 EST 2022
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells.
Cell communication and signaling : CCS
Long C,Guo R,Han R,Li K,Wan Y,Xu J,Gong X,Zhao Y,Yao X,Liu J
200-13 was used in Cell Culture to study how macrophages affect the behavior of induced pluripotent stem cells (iPSCs) by generating three macrophage subtypes and assess their effects on the proliferation, cardiac differentiation, and maturation of iPSCs.
Mon Jul 18 00:00:00 EDT 2022
Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3.
Cell reports
Li Y,Zhu Y,Feng S,Ishida Y,Chiu TP,Saito T,Wang S,Ann DK,Ou JJ
200-13 was used in Cell Culture to report that M1-like macrophages stimulated by HBV exhibit a strong HBV-suppressive effect, which is diminished in M2-like macrophages.
Tue Jan 25 00:00:00 EST 2022
Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis.
JID innovations : skin science from molecules to population health
Niehues H,Rikken G,van Vlijmen-Willems IMJJ,Rodijk-Olthuis D,van Erp PEJ,Zeeuwen PLJM,Schalkwijk J,van den Bogaard EH
200-13 was used in In vitro experiments to investigate the mitogens involved in keratinocyte proliferation and stratification.
Sat Jan 01 00:00:00 EST 2022
Differentiation and on axon-guidance chip culture of human pluripotent stem cell-derived peripheral cholinergic neurons for airway neurobiology studies.
Frontiers in pharmacology
Goldsteen PA,Sabogal Guaqueta AM,Mulder PPMFA,Bos IST,Eggens M,Van der Koog L,Soeiro JT,Halayko AJ,Mathwig K,Kistemaker LEM,Verpoorte EMJ,Dolga AM,Gosens R
200-13 was used in In vitro experiments to develop a microfluidic chip, to represent a human in vitro platform, to model neuro-effector interactions in the airways that may be used for mechanistic studies into neuroplasticity in asthma and other lung diseases.
Fri Nov 18 00:00:00 EST 2022
MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.
Scientific reports
Hansen LJ,Yang R,Roso K,Wang W,Chen L,Yang Q,Pirozzi CJ,He Y
200-13 was used in Cell Culture to investigate methylthioadenosine phosphorylase expression in glioblastoma.
Wed Mar 09 00:00:00 EST 2022
MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization.
Scientific reports
Hansen LJ,Yang R,Roso K,Wang W,Chen L,Yang Q,Pirozzi CJ,He Y
200-13 was used in Cell Culture to investigate methylthioadenosine phosphorylase expression in glioblastoma.
Wed Mar 09 00:00:00 EST 2022
Follicular regulatory T cells produce neuritin to regulate B cells.
Cell
Gonzalez-Figueroa P,Roco JA,Papa I,Núñez Villacís L,Stanley M,Linterman MA,Dent A,Canete PF,Vinuesa CG
Thu Apr 01 00:00:00 EDT 2021
Tetracyclines improve experimental lymphatic filariasis pathology by disrupting interleukin-4 receptor-mediated lymphangiogenesis.
The Journal of clinical investigation
Furlong-Silva J,Cross SD,Marriott AE,Pionnier N,Archer J,Steven A,Merker SS,Mack M,Hong YK,Taylor MJ,Turner JD
Mon Mar 01 00:00:00 EST 2021
Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation.
Cell death and differentiation
Snodgrass RG,Benatzy Y,Schmid T,Namgaladze D,Mainka M,Schebb NH,Lütjohann D,Brüne B
Thu Apr 01 00:00:00 EDT 2021
TPL Inhibits the Invasion and Migration of Drug-Resistant Ovarian Cancer by Targeting the PI3K/AKT/NF-κB-Signaling Pathway to Inhibit the Polarization of M2 TAMs.
Frontiers in oncology
Le F,Yang L,Han Y,Zhong Y,Zhan F,Feng Y,Hu H,Chen T,Tan B
200-13 was used in Cell Culture to highlight the importance of M2 TAMs in Epithelial Ovarian Cancer (EOC) migration ability, invasiveness, and resistance to DDP.
Fri Aug 13 00:00:00 EDT 2021
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Journal of cellular and molecular medicine
Hu J,Wang J,Li C,Shang Y
Tue Jun 01 00:00:00 EDT 2021
Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization.
Journal of cellular and molecular medicine
Liu Y,Du M,Lin HY
Sun Aug 01 00:00:00 EDT 2021
miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses.
Molecular medicine reports
Zhou F,Liu P,Lv H,Gao Z,Chang W,Xu Y
200-13 was used in Enzyme-linked immunosorbent assay to investigate miRNA-31 levels on allergic rhinitis.
Fri Jan 01 00:00:00 EST 2021
miR-31 attenuates murine allergic rhinitis by suppressing interleukin-13-induced nasal epithelial inflammatory responses.
Molecular medicine reports
Zhou F,Liu P,Lv H,Gao Z,Chang W,Xu Y
200-13 was used in Enzyme-linked immunosorbent assay to investigate miRNA-31 levels on allergic rhinitis.
Fri Jan 01 00:00:00 EST 2021
Ruxolitinib inhibits poly(I:C) and type 2 cytokines-induced CCL5 production in bronchial epithelial cells: A potential therapeutic agent for severe eosinophilic asthma.
Immunity, inflammation and disease
Sada M,Watanabe M,Inui T,Nakamoto K,Hirata A,Nakamura M,Honda K,Saraya T,Kurai D,Kimura H,Ishii H,Takizawa H
Tue Jun 01 00:00:00 EDT 2021
Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling.
Cell reports
Trauelsen M,Hiron TK,Lin D,Petersen JE,Breton B,Husted AS,Hjorth SA,Inoue A,Frimurer TM,Bouvier M,O'Callaghan CA,Schwartz TW
Tue Jun 15 00:00:00 EDT 2021
Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy.
Nature communications
Wang YC,Wang X,Yu J,Ma F,Li Z,Zhou Y,Zeng S,Ma X,Li YR,Neal A,Huang J,To A,Clarke N,Memarzadeh S,Pellegrini M,Yang L
Thu Jun 10 00:00:00 EDT 2021
Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.
Nature communications
Conde E,Bertrand R,Balbino B,Bonnefoy J,Stackowicz J,Caillot N,Colaone F,Hamdi S,Houmadi R,Loste A,Kamphuis JBJ,Huetz F,Guilleminault L,Gaudenzio N,Mougel A,Hardy D,Snouwaert JN,Koller BH,Serra V,Bruhns P,Grouard-Vogel G,Reber LL
Tue May 11 00:00:00 EDT 2021
Dynamic prostate cancer transcriptome analysis delineates the trajectory to disease progression.
Nature communications
Bolis M,Bossi D,Vallerga A,Ceserani V,Cavalli M,Impellizzieri D,Di Rito L,Zoni E,Mosole S,Elia AR,Rinaldi A,Pereira Mestre R,D'Antonio E,Ferrari M,Stoffel F,Jermini F,Gillessen S,Bubendorf L,Schraml P,Calcinotto A,Corey E,Moch H,Spahn M,Thalmann G,Kruithof-de Julio M,Rubin MA,Theurillat JP
200-13 was used in In vitro experiments to provide a user-friendly web-resource enabling the investigation of dynamic transcriptional perturbations linked to disease progression.
Thu Dec 02 00:00:00 EST 2021
High-throughput phenotypic screen and transcriptional analysis identify new compounds and targets for macrophage reprogramming.
Nature communications
Hu G,Su Y,Kang BH,Fan Z,Dong T,Brown DR,Cheah J,Wittrup KD,Chen J
Wed Feb 03 00:00:00 EST 2021
Cytochrome P450 26A1 Modulates the Polarization of Uterine Macrophages During the Peri-Implantation Period.
Frontiers in immunology
Ji WH,Li DD,Wei DP,Gu AQ,Yang Y,Peng JP
200-13 was used in Cell Culture to investigate whether Cytochrome P450 26A1 (CYP26A1) regulates the polarization of uterine macrophages in early pregnancy.
Thu Feb 10 00:00:00 EST 2022
Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function.
Scientific reports
Stephens M,Liao S,von der Weid PY
Thu Jan 14 00:00:00 EST 2021
Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation.
Science immunology
Niyonzima N,Rahman J,Kunz N,West EE,Freiwald T,Desai JV,Merle NS,Gidon A,Sporsheim B,Lionakis MS,Evensen K,Lindberg B,Skagen K,Skjelland M,Singh P,Haug M,Ruseva MM,Kolev M,Bibby J,Marshall O,O'Brien B,Deeks N,Afzali B,Clark RJ,Woodruff TM,Pryor M,Yang ZH,Remaley AT,Mollnes TE,Hewitt SM,Yan B,Kazemian M,Kiss MG,Binder CJ,Halvorsen B,Espevik T,Kemper C
200-13 was used in Sample Preparation (Western Blotting) to suggest that the complosome is a contributor to the biologic processes underlying sterile inflammation and indicate that targeting this system could be beneficial in macrophage-dependent diseases, such as atherosclerosis.
Fri Dec 24 00:00:00 EST 2021
In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region.
Proceedings of the National Academy of Sciences of the United States of America
Skamaki K,Emond S,Chodorge M,Andrews J,Rees DG,Cannon D,Popovic B,Buchanan A,Minter RR,Hollfelder F
Tue Nov 03 00:00:00 EST 2020
High-grade mesenchymal pancreatic ductal adenocarcinoma drives stromal deactivation through CSF-1.
EMBO reports
Steins A,van Mackelenbergh MG,van der Zalm AP,Klaassen R,Serrels B,Goris SG,Kocher HM,Waasdorp C,de Jong JH,Tekin C,Besselink MG,Busch OR,van de Vijver MJ,Verheij J,Dijk F,van Tienhoven G,Wilmink JW,Medema JP,van Laarhoven HW,Bijlsma MF
Wed May 06 00:00:00 EDT 2020
High CD206 levels in Hodgkin lymphoma-educated macrophages are linked to matrix-remodeling and lymphoma dissemination.
Molecular oncology
Arlt A,von Bonin F,Rehberg T,Perez-Rubio P,Engelmann JC,Limm K,Reinke S,Dullin C,Sun X,Specht R,Maulhardt M,Linke F,Bunt G,Klapper W,Vockerodt M,Wilting J,Pukrop T,Dettmer K,Gronwald W,Oefner PJ,Spang R,Kube D
Sun Mar 01 00:00:00 EST 2020
Human Milk Oligosaccharides Differently Modulate Goblet Cells Under Homeostatic, Proinflammatory Conditions and ER Stress.
Molecular nutrition & food research
Cheng L,Kong C,Walvoort MTC,Faas MM,de Vos P
Sun Mar 01 00:00:00 EST 2020
Resident alveolar macrophage-derived vesicular SOCS3 dampens allergic airway inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Draijer C,Speth JM,Penke LRK,Zaslona Z,Bazzill JD,Lugogo N,Huang YJ,Moon JJ,Peters-Golden M
Sun Mar 01 00:00:00 EST 2020
A human co-culture cell model incorporating microglia supports glioblastoma growth and migration, and confers resistance to cytotoxics.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Leite DM,Zvar Baskovic B,Civita P,Neto C,Gumbleton M,Pilkington GJ
Wed Jan 01 00:00:00 EST 2020
Specific Effects of Trabectedin and Lurbinectedin on Human Macrophage Function and Fate-Novel Insights.
Cancers
Povo-Retana A,Mojena M,Stremtan AB,Fernández-García VB,Gómez-Sáez A,Nuevo-Tapioles C,Molina-Guijarro JM,Avendaño-Ortiz J,Cuezva JM,López-Collazo E,Martínez-Leal JF,Boscá L
200-13 was used in In vitro experiments to study the effect of trabectedin and lurbinectedin on human macrophage cell viability and function.
Tue Oct 20 00:00:00 EDT 2020
Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction.
FASEB bioAdvances
Danahay H,Fox R,Lilley S,Charlton H,Adley K,Christie L,Ansari E,Ehre C,Flen A,Tuvim MJ,Dickey BF,Williams C,Beaudoin S,Collingwood SP,Gosling M
Sat Aug 01 00:00:00 EDT 2020
Regulatory roles of IL-10-producing human follicular T cells.
The Journal of experimental medicine
Cañete PF,Sweet RA,Gonzalez-Figueroa P,Papa I,Ohkura N,Bolton H,Roco JA,Cuenca M,Bassett KJ,Sayin I,Barry E,Lopez A,Canaday DH,Meyer-Hermann M,Doglioni C,Fazekas de St Groth B,Sakaguchi S,Cook MC,Vinuesa CG
Mon Aug 05 00:00:00 EDT 2019
M2 macrophages mediate sorafenib resistance by secreting HGF in a feed-forward manner in hepatocellular carcinoma.
British journal of cancer
Dong N,Shi X,Wang S,Gao Y,Kuang Z,Xie Q,Li Y,Deng H,Wu Y,Li M,Li JL
Mon Jul 01 00:00:00 EDT 2019
Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing inflammation via tumour-associated macrophages.
British journal of cancer
Chen Q,Wang J,Zhang Q,Zhang J,Lou Y,Yang J,Chen Y,Wei T,Zhang J,Fu Q,Ye M,Zhang X,Dang X,Liang T,Bai X
Tue Oct 01 00:00:00 EDT 2019
ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.
Mucosal immunology
Fang R,Uchiyama R,Sakai S,Hara H,Tsutsui H,Suda T,Mitsuyama M,Kawamura I,Tsuchiya K
Sun Sep 01 00:00:00 EDT 2019
Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer.
Journal of immunology (Baltimore, Md. : 1950)
Biswas S,Mandal G,Roy Chowdhury S,Purohit S,Payne KK,Anadon C,Gupta A,Swanson P,Yu X,Conejo-Garcia JR,Bhattacharyya A
Sun Dec 15 00:00:00 EST 2019
Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells.
Scientific reports
Ali MN,Mori M,Mertens TCJ,Siddhuraj P,Erjefält JS,Önnerfjord P,Hiemstra PS,Egesten A
Tue Oct 29 00:00:00 EDT 2019
The human glomerular endothelial cells are potent pro-inflammatory contributors in an in vitro model of lupus nephritis.
Scientific reports
Dimou P,Wright RD,Budge KL,Midgley A,Satchell SC,Peak M,Beresford MW
Thu Jun 06 00:00:00 EDT 2019
A juxtacrine/paracrine loop between C-Kit and stem cell factor promotes cancer stem cell survival in epithelial ovarian cancer.
Cell death & disease
Mazzoldi EL,Pavan S,Pilotto G,Leone K,Pagotto A,Frezzini S,Nicoletto MO,Amadori A,Pastò A
Tue May 28 00:00:00 EDT 2019
Engineering of anti-human interleukin-4 receptor alpha antibodies with potent antagonistic activity.
Scientific reports
Kim JE,Jung K,Kim JA,Kim SH,Park HS,Kim YS
Thu May 23 00:00:00 EDT 2019
Metabolic Reprograming of Cystic Fibrosis Macrophages via the IRE1α Arm of the Unfolded Protein Response Results in Exacerbated Inflammation.
Frontiers in immunology
Lara-Reyna S,Scambler T,Holbrook J,Wong C,Jarosz-Griffiths HH,Martinon F,Savic S,Peckham D,McDermott MF
200-13 was used in Cell Culture to investigate signalling pathways following cystic fibrosis transmembrane conductance regulator mutations.
Tue Oct 13 00:00:00 EDT 2020
Pulmonary Neuroendocrine Cells Secrete γ-Aminobutyric Acid to Induce Goblet Cell Hyperplasia in Primate Models.
American journal of respiratory cell and molecular biology
Barrios J,Kho AT,Aven L,Mitchel JA,Park JA,Randell SH,Miller LA,Tantisira KG,Ai X
200-13 was used in In vitro experiments to demonstrate an evolutionarily conserved intraepithelial GABA signaling that, in concert with IL-13, plays an essential role in mucus overproduction.
Sat Jun 01 00:00:00 EDT 2019
Transforming growth factor β1 alters the 3'-UTR of mRNA to promote lung fibrosis.
The Journal of biological chemistry
Ko J,Mills T,Huang J,Chen NY,Mertens TCJ,Collum SD,Lee G,Xiang Y,Han L,Zhou Y,Lee CG,Elias JA,Jyothula SSK,Rajagopal K,Karmouty-Quintana H,Blackburn MR
Fri Oct 25 00:00:00 EDT 2019
Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin.
Proceedings of the National Academy of Sciences of the United States of America
Plugis NM,Weng N,Zhao Q,Palanski BA,Maecker HT,Habtezion A,Khosla C
Tue Aug 28 00:00:00 EDT 2018
Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin.
Proceedings of the National Academy of Sciences of the United States of America
Plugis NM,Weng N,Zhao Q,Palanski BA,Maecker HT,Habtezion A,Khosla C
Tue Aug 28 00:00:00 EDT 2018
Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells.
Journal of immunology (Baltimore, Md. : 1950)
Otsuka Y,Watanabe E,Shinya E,Okura S,Saeki H,Geijtenbeek TBH,Takahashi H
Thu Nov 15 00:00:00 EST 2018
Golgi Phosphoprotein 2 Is a Novel Regulator of IL-12 Production and Macrophage Polarization.
Journal of immunology (Baltimore, Md. : 1950)
Zhang W,Kim H,Lv J,Zhao N,Ma X
Thu Feb 15 00:00:00 EST 2018
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Cell death & disease
Wang N,Liu W,Zheng Y,Wang S,Yang B,Li M,Song J,Zhang F,Zhang X,Wang Q,Wang Z
Wed Aug 29 00:00:00 EDT 2018
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Cell death & disease
Wang N,Liu W,Zheng Y,Wang S,Yang B,Li M,Song J,Zhang F,Zhang X,Wang Q,Wang Z
Wed Aug 29 00:00:00 EDT 2018
Hierarchical control of interleukin 13 (IL-13) signals in lung fibroblasts by STAT6 and SOX11.
The Journal of biological chemistry
Mitamura Y,Nunomura S,Nanri Y,Arima K,Yoshihara T,Komiya K,Fukuda S,Takatori H,Nakajima H,Furue M,Izuhara K
Fri Sep 21 00:00:00 EDT 2018
Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.
JCI insight
Sherrill JD,Kc K,Wang X,Wen T,Chamberlin A,Stucke EM,Collins MH,Abonia JP,Peng Y,Wu Q,Putnam PE,Dexheimer PJ,Aronow BJ,Kottyan LC,Kaufman KM,Harley JB,Huang T,Rothenberg ME
200-13 was used in In vitro experiments to investigate genes affecting eosinophilic esophagitis.
Thu Apr 19 00:00:00 EDT 2018
Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis.
JCI insight
Sherrill JD,Kc K,Wang X,Wen T,Chamberlin A,Stucke EM,Collins MH,Abonia JP,Peng Y,Wu Q,Putnam PE,Dexheimer PJ,Aronow BJ,Kottyan LC,Kaufman KM,Harley JB,Huang T,Rothenberg ME
200-13 was used in In vitro experiments to investigate genes affecting eosinophilic esophagitis.
Thu Apr 19 00:00:00 EDT 2018
USP24 induces IL-6 in tumor-associated microenvironment by stabilizing p300 and β-TrCP and promotes cancer malignancy.
Nature communications
Wang YC,Wu YS,Hung CY,Wang SA,Young MJ,Hsu TI,Hung JJ
Fri Sep 28 00:00:00 EDT 2018
Polarization of Human Macrophages by Interleukin-4 Does Not Require ATP-Citrate Lyase.
Frontiers in immunology
Namgaladze D,Zukunft S,Schnütgen F,Kurrle N,Fleming I,Fuhrmann D,Brüne B
200-13 was used in Cell Culture to suggest that ACLY may not be the major regulator of nucleocytoplasmic acetyl-CoA and IL-4-induced polarization in human macrophages.
Fri Oct 25 00:00:00 EDT 2019
Cyclic peptide *CRRETAWAC* attenuates fibronectin-induced cytokine secretion of human airway smooth muscle cells by inhibiting FAK and p38 MAPK.
Journal of cellular and molecular medicine
Chu M,Ji J,Cao W,Zhang H,Meng D,Xie B,Xu S
Sun Oct 01 00:00:00 EDT 2017
Alternatively activated macrophages derived from THP-1 cells promote the fibrogenic activities of human dermal fibroblasts.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society
Zhu Z,Ding J,Ma Z,Iwashina T,Tredget EE
200-13 was used in In vitro experiments to show differentiation of M0 and polarization of M1 and M2 macrophages.
Mon May 01 00:00:00 EDT 2017
Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.
Nature communications
Newman JP,Wang GY,Arima K,Guan SP,Waters MR,Cavenee WK,Pan E,Aliwarga E,Chong ST,Kok CYL,Endaya BB,Habib AA,Horibe T,Ng WH,Ho IAW,Hui KM,Kordula T,Lam PYP
Mon Dec 04 00:00:00 EST 2017
Lyn kinase represses mucus hypersecretion by regulating IL-13-induced endoplasmic reticulum stress in asthma.
EBioMedicine
Wang X,Yang X,Li Y,Wang X,Zhang Y,Dai X,Niu B,Wu J,Yuan X,Xiong A,Liu Z,Zhong N,Wu M,Li G
200-13 was used in Cell Culture to study potential therapeutic targets of mucus hypersecretion in asthma to show that Lyn is effector of endoplasmic reticulum stress (ER stress) and mucus hypersecretion.
Wed Feb 01 00:00:00 EST 2017
IL-33 is induced in undifferentiated, non-dividing esophageal epithelial cells in eosinophilic esophagitis.
Scientific reports
Travers J,Rochman M,Caldwell JM,Besse JA,Miracle CE,Rothenberg ME
Thu Dec 14 00:00:00 EST 2017
Cigarette smoke differentially affects IL-13-induced gene expression in human airway epithelial cells.
Physiological reports
Mertens TCJ,van der Does AM,Kistemaker LE,Ninaber DK,Taube C,Hiemstra PS
Sat Jul 01 00:00:00 EDT 2017
Sensing and responding to allergic response cytokines through a genetically encoded circuit.
Nature communications
Chassin H,Geering B,Schukur L,Ausländer D,Lang B,Fussenegger M
Tue Oct 24 00:00:00 EDT 2017
IL-4 rescues surface IgM expression in chronic lymphocytic leukemia.
Blood
Guo B,Zhang L,Chiorazzi N,Rothstein TL
Thu Jul 28 00:00:00 EDT 2016
IL-13 Inhibits Multicilin Expression and Ciliogenesis via Janus Kinase/Signal Transducer and Activator of Transcription Independently of Notch Cleavage.
American journal of respiratory cell and molecular biology
Gerovac BJ,Fregien NL
200-13 was used in Tissue/organ culture to indicate that regulation of multicilin expression by two distinct signaling pathways affects ciliated cell differentiation.
Fri Apr 01 00:00:00 EDT 2016
Bioelectric modulation of macrophage polarization.
Scientific reports
Li C,Levin M,Kaplan DL
Fri Feb 12 00:00:00 EST 2016
Liposomal prednisolone inhibits vascular inflammation and enhances venous outward remodeling in a murine arteriovenous fistula model.
Scientific reports
Wong C,Bezhaeva T,Rothuizen TC,Metselaar JM,de Vries MR,Verbeek FP,Vahrmeijer AL,Wezel A,van Zonneveld AJ,Rabelink TJ,Quax PH,Rotmans JI
Wed Jul 27 00:00:00 EDT 2016
Interleukin-13 is overexpressed in cutaneous T-cell lymphoma cells and regulates their proliferation.
Blood
Geskin LJ,Viragova S,Stolz DB,Fuschiotti P
Thu Apr 30 00:00:00 EDT 2015
Galactomyces fermentation filtrate prevents T helper 2-mediated reduction of filaggrin in an aryl hydrocarbon receptor-dependent manner.
Clinical and experimental dermatology
Takei K,Mitoma C,Hashimoto-Hachiya A,Takahara M,Tsuji G,Nakahara T,Furue M
Thu Oct 01 00:00:00 EDT 2015
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.
Nature communications
Su S,Zhao Q,He C,Huang D,Liu J,Chen F,Chen J,Liao JY,Cui X,Zeng Y,Yao H,Su F,Liu Q,Jiang S,Song E
Mon Oct 05 00:00:00 EDT 2015
Biliary repair and carcinogenesis are mediated by IL-33-dependent cholangiocyte proliferation.
The Journal of clinical investigation
Li J,Razumilava N,Gores GJ,Walters S,Mizuochi T,Mourya R,Bessho K,Wang YH,Glaser SS,Shivakumar P,Bezerra JA
Tue Jul 01 00:00:00 EDT 2014
Demethylation of the human eotaxin-3 gene promoter leads to the elevated expression of eotaxin-3.
Journal of immunology (Baltimore, Md. : 1950)
Lim E,Rothenberg ME
Wed Jan 01 00:00:00 EST 2014
Cross talk between follicular Th cells and tumor cells in human follicular lymphoma promotes immune evasion in the tumor microenvironment.
Journal of immunology (Baltimore, Md. : 1950)
Rawal S,Chu F,Zhang M,Park HJ,Nattamai D,Kannan S,Sharma R,Delgado D,Chou T,Lin HY,Baladandayuthapani V,Luong A,Vega F,Fowler N,Dong C,Davis RE,Neelapu SS
Sat Jun 15 00:00:00 EDT 2013
PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis.
Journal of immunology (Baltimore, Md. : 1950)
Chang HH,Miaw SC,Tseng W,Sun YW,Liu CC,Tsao HW,Ho IC
Sun Sep 01 00:00:00 EDT 2013
Chronic IL9 and IL-13 exposure leads to an altered differentiation of ciliated cells in a well-differentiated paediatric bronchial epithelial cell model.
PloS one
Parker JC,Thavagnanam S,Skibinski G,Lyons J,Bell J,Heaney LG,Shields MD
Tue Dec 24 00:00:00 EST 2013
Periostin promotes chronic allergic inflammation in response to Th2 cytokines.
The Journal of clinical investigation
Masuoka M,Shiraishi H,Ohta S,Suzuki S,Arima K,Aoki S,Toda S,Inagaki N,Kurihara Y,Hayashida S,Takeuchi S,Koike K,Ono J,Noshiro H,Furue M,Conway SJ,Narisawa Y,Izuhara K
Sun Jul 01 00:00:00 EDT 2012
IL-13-induced airway mucus production is attenuated by MAPK13 inhibition.
The Journal of clinical investigation
Alevy YG,Patel AC,Romero AG,Patel DA,Tucker J,Roswit WT,Miller CA,Heier RF,Byers DE,Brett TJ,Holtzman MJ
Sat Dec 01 00:00:00 EST 2012
Regulation of progranulin expression in human microglia and proteolysis of progranulin by matrix metalloproteinase-12 (MMP-12).
PloS one
Suh HS,Choi N,Tarassishin L,Lee SC
Tue Aug 07 00:00:00 EDT 2012
Interleukin-13, but not indomethacin, increases cysteinyl-leukotriene synthesis in human lung macrophages.
Journal of allergy
Jackson SE,Holloway JW,Warner JA,Sampson AP
Thu Aug 23 00:00:00 EDT 2012
Cloning and characterization of CD300d, a novel member of the human CD300 family of immune receptors.
The Journal of biological chemistry
Comas-Casellas E,Martínez-Barriocanal Á,Miró F,Ejarque-Ortiz A,Schwartz S,Martín M,Sayós J
Fri Mar 23 00:00:00 EDT 2012
Neuroimmunoendocrine regulation of the prion protein in neutrophils.
The Journal of biological chemistry
Mariante RM,Nóbrega A,Martins RAP,Areal RB,Bellio M,Linden R
Fri Oct 12 00:00:00 EDT 2012
Activation of STAT6 by STING is critical for antiviral innate immunity.
Cell
Chen H,Sun H,You F,Sun W,Zhou X,Chen L,Yang J,Wang Y,Tang H,Guan Y,Xia W,Gu J,Ishikawa H,Gutman D,Barber G,Qin Z,Jiang Z
Fri Oct 14 00:00:00 EDT 2011
STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma.
Blood
Kis LL,Gerasimcik N,Salamon D,Persson EK,Nagy N,Klein G,Severinson E,Klein E
Thu Jan 06 00:00:00 EST 2011
Macrophages at the fetal-maternal interface express markers of alternative activation and are induced by M-CSF and IL-10.
Journal of immunology (Baltimore, Md. : 1950)
Svensson J,Jenmalm MC,Matussek A,Geffers R,Berg G,Ernerudh J
Sat Oct 01 00:00:00 EDT 2011
Effects of scutellarin on MUC5AC mucin production induced by human neutrophil elastase or interleukin 13 on airway epithelial cells.
Journal of Korean medical science
Jiang DP,Perelman JM,Kolosov VP,Zhou XD
Wed Jun 01 00:00:00 EDT 2011
IL-4 and IL-13 exposure during mucociliary differentiation of bronchial epithelial cells increases antimicrobial activity and expression of antimicrobial peptides.
Respiratory research
Zuyderduyn S,Ninaber DK,Schrumpf JA,van Sterkenburg MA,Verhoosel RM,Prins FA,van Wetering S,Rabe KF,Hiemstra PS
Mon May 02 00:00:00 EDT 2011
High and low molecular weight hyaluronic acid differentially regulate human fibrocyte differentiation.
PloS one
Maharjan AS,Pilling D,Gomer RH
Fri Feb 17 00:00:00 EST 2012
Epigenetic regulation of the IL-13-induced human eotaxin-3 gene by CREB-binding protein-mediated histone 3 acetylation.
The Journal of biological chemistry
Lim EJ,Lu TX,Blanchard C,Rothenberg ME
Fri Apr 15 00:00:00 EDT 2011
Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.
Blood
Suryani S,Fulcher DA,Santner-Nanan B,Nanan R,Wong M,Shaw PJ,Gibson J,Williams A,Tangye SG
Thu Jan 21 00:00:00 EST 2010
IL-4 and TGF-beta 1 counterbalance one another while regulating mast cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950)
Macey MR,Sturgill JL,Morales JK,Falanga YT,Morales J,Norton SK,Yerram N,Shim H,Fernando J,Gifillan AM,Gomez G,Schwartz L,Oskeritzian C,Spiegel S,Conrad D,Ryan JJ
Sat May 01 00:00:00 EDT 2010
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis.
Journal of immunology (Baltimore, Md. : 1950)
Blanchard C,Stucke EM,Burwinkel K,Caldwell JM,Collins MH,Ahrens A,Buckmeier BK,Jameson SC,Greenberg A,Kaul A,Franciosi JP,Kushner JP,Martin LJ,Putnam PE,Abonia JP,Wells SI,Rothenberg ME
Thu Apr 01 00:00:00 EDT 2010
Alternatively activated macrophages engage in homotypic and heterotypic interactions through IL-4 and polyamine-induced E-cadherin/catenin complexes.
Blood
Van den Bossche J,Bogaert P,van Hengel J,Guérin CJ,Berx G,Movahedi K,Van den Bergh R,Pereira-Fernandes A,Geuns JM,Pircher H,Dorny P,Grooten J,De Baetselier P,Van Ginderachter JA
Thu Nov 19 00:00:00 EST 2009
Characterization and regulation of bv8 in human blood cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
Zhong C,Qu X,Tan M,Meng YG,Ferrara N
Wed Apr 15 00:00:00 EDT 2009
Increased intracellular, cell surface, and secreted inducible heat shock protein 70 responses are triggered during the monocyte to dendritic cell (DC) transition by cytokines independently of heat stress and infection and may positively regulate DC growth.
Journal of immunology (Baltimore, Md. : 1950)
Martin CA,Kurkowski DL,Valentino AM,Santiago-Schwarz F
Wed Jul 01 00:00:00 EDT 2009
Human activated T lymphocytes modulate IDO expression in tumors through Th1/Th2 balance.
Journal of immunology (Baltimore, Md. : 1950)
Godin-Ethier J,Pelletier S,Hanafi LA,Gannon PO,Forget MA,Routy JP,Boulassel MR,Krzemien U,Tanguay S,Lattouf JB,Arbour N,Lapointe R
Tue Dec 15 00:00:00 EST 2009
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Kurowska-Stolarska M,Stolarski B,Kewin P,Murphy G,Corrigan CJ,Ying S,Pitman N,Mirchandani A,Rana B,van Rooijen N,Shepherd M,McSharry C,McInnes IB,Xu D,Liew FY
Sun Nov 15 00:00:00 EST 2009
Small interfering RNA against transcription factor STAT6 inhibits allergic airway inflammation and hyperreactivity in mice.
Journal of immunology (Baltimore, Md. : 1950)
Darcan-Nicolaisen Y,Meinicke H,Fels G,Hegend O,Haberland A,Kühl A,Loddenkemper C,Witzenrath M,Kube S,Henke W,Hamelmann E
Mon Jun 15 00:00:00 EDT 2009
IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.
Journal of immunology (Baltimore, Md. : 1950)
Chen W,Sivaprasad U,Tabata Y,Gibson AM,Stier MT,Finkelman FD,Hershey GK
Tue Dec 15 00:00:00 EST 2009
IL-13R alpha 2 membrane and soluble isoforms differ in humans and mice.
Journal of immunology (Baltimore, Md. : 1950)
Chen W,Sivaprasad U,Tabata Y,Gibson AM,Stier MT,Finkelman FD,Hershey GK
Tue Dec 15 00:00:00 EST 2009
Regulation of alternative macrophage activation by galectin-3.
Journal of immunology (Baltimore, Md. : 1950)
MacKinnon AC,Farnworth SL,Hodkinson PS,Henderson NC,Atkinson KM,Leffler H,Nilsson UJ,Haslett C,Forbes SJ,Sethi T
Fri Feb 15 00:00:00 EST 2008
Genetically programmed differences in epidermal host defense between psoriasis and atopic dermatitis patients.
PloS one
Zeeuwen PL,de Jongh GJ,Rodijk-Olthuis D,Kamsteeg M,Verhoosel RM,van Rossum MM,Hiemstra PS,Schalkwijk J
Wed Jun 04 00:00:00 EDT 2008
Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Cassatella MA,Pereira-da-Silva G,Tinazzi I,Facchetti F,Scapini P,Calzetti F,Tamassia N,Wei P,Nardelli B,Roschke V,Vecchi A,Mantovani A,Bambara LM,Edwards SW,Carletto A
Fri Jun 01 00:00:00 EDT 2007
Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21.
Journal of immunology (Baltimore, Md. : 1950)
Good KL,Bryant VL,Tangye SG
Sun Oct 15 00:00:00 EDT 2006
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge.
The European respiratory journal
Pilette C,Francis JN,Till SJ,Durham SR
Tue Jun 01 00:00:00 EDT 2004
CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge.
The European respiratory journal
Pilette C,Francis JN,Till SJ,Durham SR
Tue Jun 01 00:00:00 EDT 2004
Active inhibition of plasma cell development in resting B cells by microphthalmia-associated transcription factor.
The Journal of experimental medicine
Lin L,Gerth AJ,Peng SL
Mon Jul 05 00:00:00 EDT 2004
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.
The Journal of allergy and clinical immunology
Chen W,Ericksen MB,Levin LS,Khurana Hershey GK
Wed Sep 01 00:00:00 EDT 2004
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.
The Journal of allergy and clinical immunology
Chen W,Ericksen MB,Levin LS,Khurana Hershey GK
Wed Sep 01 00:00:00 EDT 2004
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.
The Journal of allergy and clinical immunology
Chen W,Ericksen MB,Levin LS,Khurana Hershey GK
Wed Sep 01 00:00:00 EDT 2004
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.
The Journal of allergy and clinical immunology
Chen W,Ericksen MB,Levin LS,Khurana Hershey GK
Wed Sep 01 00:00:00 EDT 2004
Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.
The Journal of allergy and clinical immunology
Chen W,Ericksen MB,Levin LS,Khurana Hershey GK
Wed Sep 01 00:00:00 EDT 2004
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
Role of tyrosine phosphorylation in ligand-independent sequestration of CXCR4 in human primary monocytes-macrophages.
The Journal of biological chemistry
Wang J,Guan E,Roderiquez G,Calvert V,Alvarez R,Norcross MA
Fri Dec 28 00:00:00 EST 2001
