Product References
(Auto)Antibody Responses Shape Memory NK Cell Pool Size and Composition.
Biomedicines
Capuano C,Pighi C,Battella S,Pulcinelli F,Santoro C,Ferretti A,Turriziani O,De Federicis D,Fionda C,Sciumè G,Galandrini R,Palmieri G
AF-200-02 was used in Cell Culture to identify opsonizing antibodies as a host-dependent factor that shapes HCMV-driven memory NK cell compartment.
Tue Mar 08 00:00:00 EST 2022
Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis.
Nature communications
Qin L,Cui Y,Yuan T,Chen D,Zhao R,Li S,Jiang Z,Wu Q,Long Y,Wang S,Tang Z,Pan H,Li X,Wei W,Yang J,Luo X,Zhang Z,Tang Q,Liu P,Weinkove R,Yao Y,Qin D,Thiery JP,Li P
AF-200-02 was used in Cell Culture to suggest that target trans-recognition by CSRs on CAR T cells may improve the efficacy and persistence of CAR T cells via the CD70-CD27 axis.
Thu Oct 13 00:00:00 EDT 2022
A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance.
Immunity
Dikiy S,Li J,Bai L,Jiang M,Janke L,Zong X,Hao X,Hoyos B,Wang ZM,Xu B,Fan Y,Rudensky AY,Feng Y
Tue May 11 00:00:00 EDT 2021
Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade.
Cancer cell
Srivastava S,Furlan SN,Jaeger-Ruckstuhl CA,Sarvothama M,Berger C,Smythe KS,Garrison SM,Specht JM,Lee SM,Amezquita RA,Voillet V,Muhunthan V,Yechan-Gunja S,Pillai SPS,Rader C,Houghton AM,Pierce RH,Gottardo R,Maloney DG,Riddell SR
Mon Feb 08 00:00:00 EST 2021
The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer.
Cancer cell
Freed-Pastor WA,Lambert LJ,Ely ZA,Pattada NB,Bhutkar A,Eng G,Mercer KL,Garcia AP,Lin L,Rideout WM,Hwang WL,Schenkel JM,Jaeger AM,Bronson RT,Westcott PMK,Hether TD,Divakar P,Reeves JW,Deshpande V,Delorey T,Phillips D,Yilmaz OH,Regev A,Jacks T
Mon Oct 11 00:00:00 EDT 2021
Engineering genetic devices for in vivo control of therapeutic T cell activity triggered by the dietary molecule resveratrol.
Proceedings of the National Academy of Sciences of the United States of America
Yang L,Yin J,Wu J,Qiao L,Zhao EM,Cai F,Ye H
Tue Aug 24 00:00:00 EDT 2021
A T cell redirection platform for co-targeting dual antigens on solid tumors.
mAbs
Enderle L,Shalaby KH,Gorelik M,Weiss A,Blazer LL,Paduch M,Cardarelli L,Kossiakoff A,Adams JJ,Sidhu SS
AF-200-02 was used in Cell Culture to engineer the Dual Antigen T cell Engager to enable T cell activity to specific solid cancer cell features.
Tue Dec 28 00:00:00 EST 2021
Low-dose decitabine priming endows CAR T cells with enhanced and persistent antitumour potential via epigenetic reprogramming.
Nature communications
Wang Y,Tong C,Dai H,Wu Z,Han X,Guo Y,Chen D,Wei J,Ti D,Liu Z,Mei Q,Li X,Dong L,Nie J,Zhang Y,Han W
Mon Jan 18 00:00:00 EST 2021
Engineered red blood cells as an off-the-shelf allogeneic anti-tumor therapeutic.
Nature communications
Zhang X,Luo M,Dastagir SR,Nixon M,Khamhoung A,Schmidt A,Lee A,Subbiah N,McLaughlin DC,Moore CL,Gribble M,Bayhi N,Amin V,Pepi R,Pawar S,Lyford TJ,Soman V,Mellen J,Carpenter CL,Turka LA,Wickham TJ,Chen TF
Tue May 11 00:00:00 EDT 2021
Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia.
Scientific reports
Inano T,Araki M,Morishita S,Imai M,Kihara Y,Okuda M,Yang Y,Ito M,Osaga S,Mano H,Edahiro Y,Ochiai T,Misawa K,Fukuda Y,Ando J,Komatsu N
Mon Sep 06 00:00:00 EDT 2021
Listeria monocytogenes-infected human monocytic derived dendritic cells activate Vγ9Vδ2 T cells independently of HMBPP production.
Scientific reports
Alice AF,Kramer G,Bambina S,Bahjat KS,Gough MJ,Crittenden MR
Wed Aug 11 00:00:00 EDT 2021
Type I interferons affect the metabolic fitness of CD8+ T cells from patients with systemic lupus erythematosus.
Nature communications
Buang N,Tapeng L,Gray V,Sardini A,Whilding C,Lightstone L,Cairns TD,Pickering MC,Behmoaras J,Ling GS,Botto M
Wed Mar 31 00:00:00 EDT 2021
A CAR RNA FISH assay to study functional and spatial heterogeneity of chimeric antigen receptor T cells in tissue.
Scientific reports
Eichholz K,Li AZ,Diem K,Jensen MC,Zhu J,Corey L
Mon Jun 21 00:00:00 EDT 2021
A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function.
Communications biology
To J,Quackenbush D,Rowell E,Li L,Reed C,Lo F,Horman SR
Fri Jan 08 00:00:00 EST 2021
CRISPR-Cas9 cytidine and adenosine base editing of splice-sites mediates highly-efficient disruption of proteins in primary and immortalized cells.
Nature communications
Kluesner MG,Lahr WS,Lonetree CL,Smeester BA,Qiu X,Slipek NJ,Claudio Vázquez PN,Pitzen SP,Pomeroy EJ,Vignes MJ,Lee SC,Bingea SP,Andrew AA,Webber BR,Moriarity BS
Fri Apr 23 00:00:00 EDT 2021
Breast cancer-derived exosomes transmit lncRNA SNHG16 to induce CD73+γδ1 Treg cells.
Signal transduction and targeted therapy
Ni C,Fang QQ,Chen WZ,Jiang JX,Jiang Z,Ye J,Zhang T,Yang L,Meng FB,Xia WJ,Zhong M,Huang J
Wed Apr 29 00:00:00 EDT 2020
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours.
The EMBO journal
Wiede F,Lu KH,Du X,Liang S,Hochheiser K,Dodd GT,Goh PK,Kearney C,Meyran D,Beavis PA,Henderson MA,Park SL,Waithman J,Zhang S,Zhang ZY,Oliaro J,Gebhardt T,Darcy PK,Tiganis T
Wed Jan 15 00:00:00 EST 2020
CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesis.
The EMBO journal
Martín-Leal A,Blanco R,Casas J,Sáez ME,Rodríguez-Bovolenta E,de Rojas I,Drechsler C,Real LM,Fabrias G,Ruíz A,Castro M,Schamel WW,Alarcón B,van Santen HM,Mañes S
Mon Aug 03 00:00:00 EDT 2020
Mesenchymal stromal cells induce regulatory T cells via epigenetic conversion of human conventional CD4 T cells in vitro.
Stem cells (Dayton, Ohio)
Azevedo RI,Minskaia E,Fernandes-Platzgummer A,Vieira AIS,da Silva CL,Cabral JMS,Lacerda JF
Sat Aug 01 00:00:00 EDT 2020
CD4+ Th immunogenicity of the Ascaris spp. secreted products.
NPJ vaccines
Ebner F,Morrison E,Bertazzon M,Midha A,Hartmann S,Freund C,Álvaro-Benito M
Thu Mar 18 00:00:00 EDT 2021
MUC1 as a target for CAR-T therapy in head and neck squamous cell carinoma.
Cancer medicine
Mei Z,Zhang K,Lam AK,Huang J,Qiu F,Qiao B,Zhang Y
Wed Jan 01 00:00:00 EST 2020
Assessment of long non-coding RNA expression reveals novel mediators of the lung tumour immune response.
Scientific reports
Sage AP,Ng KW,Marshall EA,Stewart GL,Minatel BC,Enfield KSS,Martin SD,Brown CJ,Abraham N,Lam WL
Fri Oct 09 00:00:00 EDT 2020
Tumoral and paratumoral NK cells and CD8+ T cells of esophageal carcinoma patients express high levels of CD47.
Scientific reports
Strizova Z,Vachtenheim J,Snajdauf M,Lischke R,Bartunkova J,Smrz D
Tue Aug 18 00:00:00 EDT 2020
Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibition.
Nature communications
Lee JH,Shklovskaya E,Lim SY,Carlino MS,Menzies AM,Stewart A,Pedersen B,Irvine M,Alavi S,Yang JYH,Strbenac D,Saw RPM,Thompson JF,Wilmott JS,Scolyer RA,Long GV,Kefford RF,Rizos H
Mon Apr 20 00:00:00 EDT 2020
Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma.
Nature communications
Tseng HC,Xiong W,Badeti S,Yang Y,Ma M,Liu T,Ramos CA,Dotti G,Fritzky L,Jiang JG,Yi Q,Guarrera J,Zong WX,Liu C,Liu D
Wed Sep 23 00:00:00 EDT 2020
Single-cell RNA sequencing reveals the heterogeneity of liver-resident immune cells in human.
Cell discovery
Zhao J,Zhang S,Liu Y,He X,Qu M,Xu G,Wang H,Huang M,Pan J,Liu Z,Li Z,Liu L,Zhang Z
Tue Oct 03 00:00:00 EDT 2023
Cytokines regulate the antigen-presenting characteristics of human circulating and tissue-resident intestinal ILCs.
Nature communications
Rao A,Strauss O,Kokkinou E,Bruchard M,Tripathi KP,Schlums H,Carrasco A,Mazzurana L,Konya V,Villablanca EJ,Björkström NK,Lindforss U,Spits H,Mjösberg J
Mon Apr 27 00:00:00 EDT 2020
Genomic programming of IRF4-expressing human Langerhans cells.
Nature communications
Sirvent S,Vallejo AF,Davies J,Clayton K,Wu Z,Woo J,Riddell J,Chaudhri VK,Stumpf P,Nazlamova LA,Wheway G,Rose-Zerilli M,West J,Pujato M,Chen X,Woelk CH,MacArthur B,Ardern-Jones M,Friedmann PS,Weirauch MT,Singh H,Polak ME
Thu Jan 16 00:00:00 EST 2020
Gene correction for SCID-X1 in long-term hematopoietic stem cells.
Nature communications
Pavel-Dinu M,Wiebking V,Dejene BT,Srifa W,Mantri S,Nicolas CE,Lee C,Bao G,Kildebeck EJ,Punjya N,Sindhu C,Inlay MA,Saxena N,DeRavin SS,Malech H,Roncarolo MG,Weinberg KI,Porteus MH
Tue Apr 09 00:00:00 EDT 2019
TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases.
Cell reports
Yang BH,Wang K,Wan S,Liang Y,Yuan X,Dong Y,Cho S,Xu W,Jepsen K,Feng GS,Lu LF,Xue HH,Fu W
AF-200-02 was used in Cell Culture to study how CD4+ Foxp3+ T regulatory (Treg) cell differentiation and functional specification is regulated.
Tue Jun 18 00:00:00 EDT 2019
NK cells are activated and primed for skin-homing during acute dengue virus infection in humans.
Nature communications
Zimmer CL,Cornillet M,Solà-Riera C,Cheung KW,Ivarsson MA,Lim MQ,Marquardt N,Leo YS,Lye DC,Klingström J,MacAry PA,Ljunggren HG,Rivino L,Björkström NK
Thu Aug 29 00:00:00 EDT 2019
A CD146 FACS Protocol Enriches for Luminal Keratin 14/19 Double Positive Human Breast Progenitors.
Scientific reports
Ísberg ÓG,Kim J,Fridriksdottir AJ,Morsing M,Timmermans-Wielenga V,Rønnov-Jessen L,Petersen OW,Villadsen R
Wed Oct 16 00:00:00 EDT 2019
Improving CLL Vγ9Vδ2-T-cell fitness for cellular therapy by ex vivo activation and ibrutinib.
Blood
de Weerdt I,Hofland T,Lameris R,Endstra S,Jongejan A,Moerland PD,de Bruin RCG,Remmerswaal EBM,Ten Berge IJM,Liu N,van der Stelt M,Faber LM,Levin MD,Eldering E,Tonino SH,de Gruijl TD,van der Vliet HJ,Kater AP
Thu Nov 22 00:00:00 EST 2018
Anti-colorectal cancer effects of anti-p21Ras scFv delivered by the recombinant adenovirus KGHV500 and cytokine-induced killer cells.
BMC cancer
Liu FR,Bai S,Feng Q,Pan XY,Song SL,Fang H,Cui J,Yang JL
AF-200-02 was used in Cell Culture to provide a novel strategy for the treatment of colorectal cancer by combining CIK cells with the recombinant adenovirus KGHV500 which carried anti-p21 Ras scFv.
Mon Nov 12 00:00:00 EST 2018
Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells.
Clinical and experimental immunology
Tan MP,Dolton GM,Gerry AB,Brewer JE,Bennett AD,Pumphrey NJ,Jakobsen BK,Sewell AK
Sun Jan 01 00:00:00 EST 2017
Malignant Mesothelioma Effusions Are Infiltrated by CD3+ T Cells Highly Expressing PD-L1 and the PD-L1+ Tumor Cells within These Effusions Are Susceptible to ADCC by the Anti-PD-L1 Antibody Avelumab.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
Khanna S,Thomas A,Abate-Daga D,Zhang J,Morrow B,Steinberg SM,Orlandi A,Ferroni P,Schlom J,Guadagni F,Hassan R
AF-200-02 was used in Sample Preparation (FC/FACS) to study the functional aspects of programmed death 1 (PD-1) and PD ligand 1 (PD-L1) immune checkpoints in malignant mesothelioma.
Tue Nov 01 00:00:00 EDT 2016
Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells.
Immunology
Modak M,Majdic O,Cejka P,Jutz S,Puck A,Gerwien JG,Steinberger P,Zlabinger GJ,Strobl H,Stöckl J
Tue Nov 01 00:00:00 EDT 2016
Follistatin-like protein 1 contributes to dendritic cell and T-lymphocyte activation in nasopharyngeal carcinoma patients by altering nuclear factor κb and Jun N-terminal kinase expression.
Cell biochemistry and function
Wang H,Wu S,Huang S,Yin S,Zou G,Huang K,Zhang Z,Tang A,Wen W
Thu Dec 01 00:00:00 EST 2016
Distinct immunological activation profiles of dSLIM® and ProMune® depend on their different structural context.
Immunity, inflammation and disease
Kapp K,Schneider J,Schneider L,Gollinge N,Jänsch S,Schroff M,Wittig B,Kleuss C
Thu Dec 01 00:00:00 EST 2016
Quiescence of Memory CD8(+) T Cells Is Mediated by Regulatory T Cells through Inhibitory Receptor CTLA-4.
Immunity
Kalia V,Penny LA,Yuzefpolskiy Y,Baumann FM,Sarkar S
Tue Jun 16 00:00:00 EDT 2015
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors.
Blood
Cieri N,Camisa B,Cocchiarella F,Forcato M,Oliveira G,Provasi E,Bondanza A,Bordignon C,Peccatori J,Ciceri F,Lupo-Stanghellini MT,Mavilio F,Mondino A,Bicciato S,Recchia A,Bonini C
Thu Jan 24 00:00:00 EST 2013
CTLA-4 promotes Foxp3 induction and regulatory T cell accumulation in the intestinal lamina propria.
Mucosal immunology
Barnes MJ,Griseri T,Johnson AM,Young W,Powrie F,Izcue A
Fri Mar 01 00:00:00 EST 2013
IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells.
Journal of immunology (Baltimore, Md. : 1950)
Ding BB,Bi E,Chen H,Yu JJ,Ye BH
Fri Feb 15 00:00:00 EST 2013
Foxp3+ Treg expanded from patients with established diabetes reduce Helios expression while retaining normal function compared to healthy individuals.
PloS one
Du W,Shen YW,Lee WH,Wang D,Paz S,Kandeel F,Liu CP
Mon Jul 29 00:00:00 EDT 2013
Suppression of natural killer cells by sorafenib contributes to prometastatic effects in hepatocellular carcinoma.
PloS one
Zhang QB,Sun HC,Zhang KZ,Jia QA,Bu Y,Wang M,Chai ZT,Zhang QB,Wang WQ,Kong LQ,Zhu XD,Lu L,Wu WZ,Wang L,Tang ZY
Mon Aug 05 00:00:00 EDT 2013
High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas.
Blood
Zocchi MR,Catellani S,Canevali P,Tavella S,Garuti A,Villaggio B,Zunino A,Gobbi M,Fraternali-Orcioni G,Kunkl A,Ravetti JL,Boero S,Musso A,Poggi A
Thu Feb 09 00:00:00 EST 2012
Mast cells play a protumorigenic role in primary cutaneous lymphoma.
Blood
Rabenhorst A,Schlaak M,Heukamp LC,Förster A,Theurich S,von Bergwelt-Baildon M,Büttner R,Kurschat P,Mauch C,Roers A,Hartmann K
Thu Sep 06 00:00:00 EDT 2012
Cell-autonomous role of TGFβ and IL-2 receptors in CD4+ and CD8+ inducible regulatory T-cell generation during GVHD.
Blood
Sawamukai N,Satake A,Schmidt AM,Lamborn IT,Ojha P,Tanaka Y,Kambayashi T
Thu Jun 07 00:00:00 EDT 2012
Antibody-dependent anti-cytomegalovirus activity of human γδ T cells expressing CD16 (FcγRIIIa).
Blood
Couzi L,Pitard V,Sicard X,Garrigue I,Hawchar O,Merville P,Moreau JF,Déchanet-Merville J
Thu Feb 09 00:00:00 EST 2012
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.
The Journal of clinical investigation
Brüstle A,Brenner D,Knobbe CB,Lang PA,Virtanen C,Hershenfield BM,Reardon C,Lacher SM,Ruland J,Ohashi PS,Mak TW
Sat Dec 01 00:00:00 EST 2012
Neuropilin 1 is expressed on thymus-derived natural regulatory T cells, but not mucosa-generated induced Foxp3+ T reg cells.
The Journal of experimental medicine
Weiss JM,Bilate AM,Gobert M,Ding Y,Curotto de Lafaille MA,Parkhurst CN,Xiong H,Dolpady J,Frey AB,Ruocco MG,Yang Y,Floess S,Huehn J,Oh S,Li MO,Niec RE,Rudensky AY,Dustin ML,Littman DR,Lafaille JJ
Mon Sep 24 00:00:00 EDT 2012
Congenital B cell lymphocytosis explained by novel germline CARD11 mutations.
The Journal of experimental medicine
Snow AL,Xiao W,Stinson JR,Lu W,Chaigne-Delalande B,Zheng L,Pittaluga S,Matthews HF,Schmitz R,Jhavar S,Kuchen S,Kardava L,Wang W,Lamborn IT,Jing H,Raffeld M,Moir S,Fleisher TA,Staudt LM,Su HC,Lenardo MJ
Mon Nov 19 00:00:00 EST 2012
Polymerase ε1 mutation in a human syndrome with facial dysmorphism, immunodeficiency, livedo, and short stature ("FILS syndrome").
The Journal of experimental medicine
Pachlopnik Schmid J,Lemoine R,Nehme N,Cormier-Daire V,Revy P,Debeurme F,Debré M,Nitschke P,Bole-Feysot C,Legeai-Mallet L,Lim A,de Villartay JP,Picard C,Durandy A,Fischer A,de Saint Basile G
Mon Dec 17 00:00:00 EST 2012
Dependence on nuclear factor of activated T-cells (NFAT) levels discriminates conventional T cells from Foxp3+ regulatory T cells.
Proceedings of the National Academy of Sciences of the United States of America
Vaeth M,Schliesser U,Müller G,Reissig S,Satoh K,Tuettenberg A,Jonuleit H,Waisman A,Müller MR,Serfling E,Sawitzki BS,Berberich-Siebelt F
Tue Oct 02 00:00:00 EDT 2012
Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proceedings of the National Academy of Sciences of the United States of America
Ostrov DA,Grant BJ,Pompeu YA,Sidney J,Harndahl M,Southwood S,Oseroff C,Lu S,Jakoncic J,de Oliveira CA,Yang L,Mei H,Shi L,Shabanowitz J,English AM,Wriston A,Lucas A,Phillips E,Mallal S,Grey HM,Sette A,Hunt DF,Buus S,Peters B
Tue Jun 19 00:00:00 EDT 2012
Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells.
Proceedings of the National Academy of Sciences of the United States of America
Benson MJ,Aijö T,Chang X,Gagnon J,Pape UJ,Anantharaman V,Aravind L,Pursiheimo JP,Oberdoerffer S,Liu XS,Lahesmaa R,Lähdesmäki H,Rao A
Tue Oct 02 00:00:00 EDT 2012
Human responses against HER-2-positive cancer cells in human immune system-engrafted mice.
British journal of cancer
De Giovanni C,Nicoletti G,Landuzzi L,Romani F,Croci S,Palladini A,Murgo A,Antognoli A,Ianzano ML,Stivani V,Grosso V,Iezzi M,Stramucci L,Barbieri E,Lemoli RM,Nanni P,Lollini PL
Tue Oct 09 00:00:00 EDT 2012
Human responses against HER-2-positive cancer cells in human immune system-engrafted mice.
British journal of cancer
De Giovanni C,Nicoletti G,Landuzzi L,Romani F,Croci S,Palladini A,Murgo A,Antognoli A,Ianzano ML,Stivani V,Grosso V,Iezzi M,Stramucci L,Barbieri E,Lemoli RM,Nanni P,Lollini PL
Tue Oct 09 00:00:00 EDT 2012
Relatively low level of antigen-specific monocytes detected in blood from untreated tuberculosis patients using CD4+ T-cell receptor tetramers.
PLoS pathogens
Huang Y,Huang Y,Fang Y,Wang J,Li Y,Wang N,Zhang J,Gao M,Huang L,Yang F,Wang C,Lin S,Yao Y,Ren L,Chen Y,Du X,Xie D,Wu R,Zhang K,Jiang L,Yu X,Lai X
Fri Apr 19 00:00:00 EDT 2013
Mycobacteria activate γδ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy.
Cancer immunology, immunotherapy : CII
Fowler DW,Copier J,Wilson N,Dalgleish AG,Bodman-Smith MD
Sun Apr 01 00:00:00 EDT 2012
Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity.
Arthritis research & therapy
Li Y,Zhao LD,Tong LS,Qian SN,Ren Y,Zhang L,Ding X,Chen Y,Wang YX,Zhang W,Zeng XF,Zhang FC,Tang FL,Zhang X,Ba DN,He W,Cao XT,Lipsky PE
Wed May 23 00:00:00 EDT 2012
IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model.
Journal of molecular medicine (Berlin, Germany)
Schilling B,Harasymczuk M,Schuler P,Egan JE,Whiteside TL
Wed Feb 01 00:00:00 EST 2012
Contact-dependent interference with invariant NKT cell activation by herpes simplex virus-infected cells.
Journal of immunology (Baltimore, Md. : 1950)
Bosnjak L,Sahlström P,Paquin-Proulx D,Leeansyah E,Moll M,Sandberg JK
Fri Jun 15 00:00:00 EDT 2012
Availability of 25-hydroxyvitamin D(3) to APCs controls the balance between regulatory and inflammatory T cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Jeffery LE,Wood AM,Qureshi OS,Hou TZ,Gardner D,Briggs Z,Kaur S,Raza K,Sansom DM
Sat Dec 01 00:00:00 EST 2012
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tkach M,Coria L,Rosemblit C,Rivas MA,Proietti CJ,Díaz Flaqué MC,Beguelin W,Frahm I,Charreau EH,Cassataro J,Elizalde PV,Schillaci R
Wed Aug 01 00:00:00 EDT 2012
CD8 T cell priming in the presence of IFN-α renders CTLs with improved responsiveness to homeostatic cytokines and recall antigens: important traits for adoptive T cell therapy.
Journal of immunology (Baltimore, Md. : 1950)
Hervas-Stubbs S,Mancheño U,Riezu-Boj JI,Larraga A,Ochoa MC,Alignani D,Alfaro C,Morales-Kastresana A,Gonzalez I,Larrea E,Pircher H,Le Bon A,Lopez-Picazo JM,Martín-Algarra S,Prieto J,Melero I
Mon Oct 01 00:00:00 EDT 2012
Primary MHC-class II(+) cells are necessary to promote resting Vδ2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate.
Journal of immunology (Baltimore, Md. : 1950)
Soriano-Sarabia N,Sandvold H,Jomaa H,Kubin T,Bein G,Hackstein H
Sat Dec 01 00:00:00 EST 2012
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.
Journal of immunology (Baltimore, Md. : 1950)
Pham D,Vincentz JW,Firulli AB,Kaplan MH
Sun Jul 15 00:00:00 EDT 2012
Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.
Journal of immunology (Baltimore, Md. : 1950)
Antal Z,Baker JC,Smith C,Jarchum I,Babad J,Mukherjee G,Yang Y,Sidney J,Sette A,Santamaria P,DiLorenzo TP
Fri Jun 01 00:00:00 EDT 2012
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950)
Benoit ME,Clarke EV,Morgado P,Fraser DA,Tenner AJ
Fri Jun 01 00:00:00 EDT 2012
L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950)
Freeley M,O'Dowd F,Paul T,Kashanin D,Davies A,Kelleher D,Long A
Fri Jun 15 00:00:00 EDT 2012
Expression of Helios in peripherally induced Foxp3+ regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950)
Gottschalk RA,Corse E,Allison JP
Wed Feb 01 00:00:00 EST 2012
TCR-redirected human T cells inhibit hepatitis C virus replication: hepatotoxic potential is linked to antigen specificity and functional avidity.
Journal of immunology (Baltimore, Md. : 1950)
Pasetto A,Frelin L,Aleman S,Holmström F,Brass A,Ahlén G,Brenndörfer ED,Lohmann V,Bartenschlager R,Sällberg M,Bertoletti A,Chen M
Thu Nov 01 00:00:00 EDT 2012
Fyn promotes Th17 differentiation by regulating the kinetics of RORγt and Foxp3 expression.
Journal of immunology (Baltimore, Md. : 1950)
Ueda A,Zhou L,Stein PL
Fri Jun 01 00:00:00 EDT 2012
Crosstalk between human IgG isotypes and murine effector cells.
Journal of immunology (Baltimore, Md. : 1950)
Overdijk MB,Verploegen S,Ortiz Buijsse A,Vink T,Leusen JH,Bleeker WK,Parren PW
Mon Oct 01 00:00:00 EDT 2012
Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype.
Cellular microbiology
Portevin D,Via LE,Eum S,Young D
Thu Nov 01 00:00:00 EDT 2012
A pivotal role of vitamin B9 in the maintenance of regulatory T cells in vitro and in vivo.
PloS one
Kunisawa J,Hashimoto E,Ishikawa I,Kiyono H
Fri Jun 29 00:00:00 EDT 2012
Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling.
The Journal of biological chemistry
Verma NK,Dempsey E,Long A,Davies A,Barry SP,Fallon PG,Volkov Y,Kelleher D
Fri Aug 03 00:00:00 EDT 2012
The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
PloS one
Qi Y,Operario DJ,Georas SN,Mosmann TR
Thu Dec 13 00:00:00 EST 2012
Stimulation of Wnt/ß-catenin pathway in human CD8+ T lymphocytes from blood and lung tumors leads to a shared young/memory phenotype.
PloS one
Forget MA,Huon Y,Reuben A,Grange C,Liberman M,Martin J,Mes-Masson AM,Arbour N,Lapointe R
Thu Apr 11 00:00:00 EDT 2013
DCs pulsed with novel HLA-A2-restricted CTL epitopes against hepatitis C virus induced a broadly reactive anti-HCV-specific T lymphocyte response.
PloS one
Guo Z,Zhang H,Rao H,Jiang D,Cong X,Feng B,Wang J,Wei L,Chen H
Thu Nov 08 00:00:00 EST 2012
The scaffolding protein Dlg1 is a negative regulator of cell-free virus infectivity but not of cell-to-cell HIV-1 transmission in T cells.
PloS one
Nzounza P,Chazal M,Guedj C,Schmitt A,Massé JM,Randriamampita C,Pique C,Ramirez BC
Mon Jun 11 00:00:00 EDT 2012
Pegylated interferon α enhances recovery of memory T cells in e antigen positive chronic hepatitis B patients.
Virology journal
Liu YZ,Hou FQ,Ding P,Ren YY,Li SH,Wang GQ
Fri Nov 16 00:00:00 EST 2012
Optimal population of FoxP3+ T cells in tumors requires an antigen priming-dependent trafficking receptor switch.
PloS one
Wang C,Lee JH,Kim CH
Mon Jun 04 00:00:00 EDT 2012
Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function.
Retrovirology
Meuwissen PJ,Stolp B,Iannucci V,Vermeire J,Naessens E,Saksela K,Geyer M,Vanham G,Arien KK,Fackler OT,Verhasselt B
Fri Apr 27 00:00:00 EDT 2012
Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.
The Journal of biological chemistry
Macaire H,Riquet A,Moncollin V,Biémont-Trescol MC,Duc Dodon M,Hermine O,Debaud AL,Mahieux R,Mesnard JM,Pierre M,Gazzolo L,Bonnefoy N,Valentin H
Fri Jun 15 00:00:00 EDT 2012
CD99 ligation upregulates HSP70 on acute lymphoblastic leukemia cells and concomitantly increases NK cytotoxicity.
Cell death & disease
Husak Z,Dworzak MN
Thu Nov 15 00:00:00 EST 2012
T-cell receptor-optimized peptide skewing of the T-cell repertoire can enhance antigen targeting.
The Journal of biological chemistry
Ekeruche-Makinde J,Clement M,Cole DK,Edwards ES,Ladell K,Miles JJ,Matthews KK,Fuller A,Lloyd KA,Madura F,Dolton GM,Pentier J,Lissina A,Gostick E,Baxter TK,Baker BM,Rizkallah PJ,Price DA,Wooldridge L,Sewell AK
Fri Oct 26 00:00:00 EDT 2012
Anticancer drugs cause release of exosomes with heat shock proteins from human hepatocellular carcinoma cells that elicit effective natural killer cell antitumor responses in vitro.
The Journal of biological chemistry
Lv LH,Wan YL,Lin Y,Zhang W,Yang M,Li GL,Lin HM,Shang CZ,Chen YJ,Min J
Fri May 04 00:00:00 EDT 2012
MHC class I-presented T cell epitopes identified by immunoproteomics analysis are targets for a cross reactive influenza-specific T cell response.
PloS one
Testa JS,Shetty V,Hafner J,Nickens Z,Kamal S,Sinnathamby G,Philip R
Wed Apr 24 00:00:00 EDT 2013
Characterization of T-cell responses against IκBα in cancer patients.
Oncoimmunology
Munir S,Frøsig TM,Hansen M,Svane IM,Andersen MH
Thu Nov 01 00:00:00 EDT 2012
Human natural killer cell maturation defect supports in vivo CD56(bright) to CD56(dim) lineage development.
PloS one
Domaica CI,Fuertes MB,Uriarte I,Girart MV,Sardañons J,Comas DI,Di Giovanni D,Gaillard MI,Bezrodnik L,Zwirner NW
Thu May 30 00:00:00 EDT 2013
Macrophages help NK cells to attack tumor cells by stimulatory NKG2D ligand but protect themselves from NK killing by inhibitory ligand Qa-1.
PloS one
Zhou Z,Zhang C,Zhang J,Tian Z
Mon Dec 17 00:00:00 EST 2012
Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naïve T cells into cytokine-producing mature T cells.
PloS one
Tsuda K,Yamanaka K,Kitagawa H,Akeda T,Naka M,Niwa K,Nakanishi T,Kakeda M,Gabazza EC,Mizutani H
Fri Aug 03 00:00:00 EDT 2012
Authentication of primordial characteristics of the CLBL-1 cell line prove the integrity of a canine B-cell lymphoma in a murine in vivo model.
PloS one
Rütgen BC,Willenbrock S,Reimann-Berg N,Walter I,Fuchs-Baumgartinger A,Wagner S,Kovacic B,Essler SE,Schwendenwein I,Nolte I,Saalmüller A,Murua Escobar H
Fri Jan 04 00:00:00 EST 2013
Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells.
The Journal of biological chemistry
Müller JR,Waldmann TA,Kruhlak MJ,Dubois S
Fri Nov 23 00:00:00 EST 2012
Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex.
The Journal of biological chemistry
Wun KS,Ross F,Patel O,Besra GS,Porcelli SA,Richardson SK,Keshipeddy S,Howell AR,Godfrey DI,Rossjohn J
Fri Nov 09 00:00:00 EST 2012
T-cell immunotherapy with a chimeric receptor against CD38 is effective in eradicating chemotherapy-resistant B-cell lymphoma cells overexpressing survivin induced by BMI-1.
Blood cancer journal
Bhattacharyya J,Mihara K,Kitanaka A,Yanagihara K,Kubo T,Takei Y,Kimura A,Takihara Y
Fri Jun 01 00:00:00 EDT 2012
Natural CD4+ T-cell responses against indoleamine 2,3-dioxygenase.
PloS one
Munir S,Larsen SK,Iversen TZ,Donia M,Klausen TW,Svane IM,Straten PT,Andersen MH
Mon Sep 10 00:00:00 EDT 2012
CD26 expression and adenosine deaminase activity in regulatory T cells (Treg) and CD4(+) T effector cells in patients with head and neck squamous cell carcinoma.
Oncoimmunology
Mandapathil M,Szczepanski M,Harasymczuk M,Ren J,Cheng D,Jackson EK,Gorelik E,Johnson J,Lang S,Whiteside TL
Wed Aug 01 00:00:00 EDT 2012
Activation of STAT6 by STING is critical for antiviral innate immunity.
Cell
Chen H,Sun H,You F,Sun W,Zhou X,Chen L,Yang J,Wang Y,Tang H,Guan Y,Xia W,Gu J,Ishikawa H,Gutman D,Barber G,Qin Z,Jiang Z
Fri Oct 14 00:00:00 EDT 2011
T(H)1, T(H)2, and T(H)17 cells instruct monocytes to differentiate into specialized dendritic cell subsets.
Blood
Alonso MN,Wong MT,Zhang AL,Winer D,Suhoski MM,Tolentino LL,Gaitan J,Davidson MG,Kung TH,Galel DM,Nadeau KC,Kim J,Utz PJ,Söderström K,Engleman EG
Thu Sep 22 00:00:00 EDT 2011
Human microRNA-27a* targets Prf1 and GzmB expression to regulate NK-cell cytotoxicity.
Blood
Kim TD,Lee SU,Yun S,Sun HN,Lee SH,Kim JW,Kim HM,Park SK,Lee CW,Yoon SR,Greenberg PD,Choi I
Thu Nov 17 00:00:00 EST 2011
Paracrine inhibition of GM-CSF signaling by human cytomegalovirus in monocytes differentiating to dendritic cells.
Blood
Carlier J,Martin H,Mariamé B,Rauwel B,Mengelle C,Weclawiak H,Coaquette A,Vauchy C,Rohrlich P,Kamar N,Rostaing L,Herbein G,Davrinche C
Thu Dec 22 00:00:00 EST 2011
Control of Plasmodium falciparum erythrocytic cycle: γδ T cells target the red blood cell-invasive merozoites.
Blood
Costa G,Loizon S,Guenot M,Mocan I,Halary F,de Saint-Basile G,Pitard V,Déchanet-Merville J,Moreau JF,Troye-Blomberg M,Mercereau-Puijalon O,Behr C
Thu Dec 22 00:00:00 EST 2011
Mobilization of natural killer cells inhibits development of collagen-induced arthritis.
Proceedings of the National Academy of Sciences of the United States of America
Leavenworth JW,Wang X,Wenander CS,Spee P,Cantor H
Tue Aug 30 00:00:00 EDT 2011
Acquisition of pneumococci specific effector and regulatory Cd4+ T cells localising within human upper respiratory-tract mucosal lymphoid tissue.
PLoS pathogens
Pido-Lopez J,Kwok WW,Mitchell TJ,Heyderman RS,Williams NA
Thu Dec 01 00:00:00 EST 2011
A new look at immune privilege of the eye: dual role for the vision-related molecule retinoic acid.
Journal of immunology (Baltimore, Md. : 1950)
Zhou R,Horai R,Mattapallil MJ,Caspi RR
Sat Oct 15 00:00:00 EDT 2011
A new look at immune privilege of the eye: dual role for the vision-related molecule retinoic acid.
Journal of immunology (Baltimore, Md. : 1950)
Zhou R,Horai R,Mattapallil MJ,Caspi RR
Sat Oct 15 00:00:00 EDT 2011
Human ovarian tumor cells escape γδ T cell recognition partly by down regulating surface expression of MICA and limiting cell cycle related molecules.
PloS one
Lu J,Aggarwal R,Kanji S,Das M,Joseph M,Pompili V,Das H
Fri Apr 13 00:00:00 EDT 2012
Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials.
Journal of translational medicine
Fučíková J,Rožková D,Ulčová H,Budinský V,Sochorová K,Pokorná K,Bartůňková J,Špíšek R
Fri Dec 30 00:00:00 EST 2011
Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals.
PloS one
Iguchi-Hashimoto M,Usui T,Yoshifuji H,Shimizu M,Kobayashi S,Ito Y,Murakami K,Shiomi A,Yukawa N,Kawabata D,Nojima T,Ohmura K,Fujii T,Mimori T
Mon Mar 26 00:00:00 EDT 2012
Evaluation of Epstein-Barr virus latent membrane protein 2 specific T-cell receptors driven by T-cell specific promoters using lentiviral vector.
Clinical & developmental immunology
Yang D,Shao Q,Sun H,Mu X,Gao Y,Jiang R,Hou J,Yao K,Chen Y,Sun B
Wed Jan 18 00:00:00 EST 2012
Plasmodium falciparum-infected erythrocytes and IL-12/IL-18 induce diverse transcriptomes in human NK cells: IFN-α/β pathway versus TREM signaling.
PloS one
Grangeiro de Carvalho E,Bonin M,Kremsner PG,Kun JF
Fri Feb 03 00:00:00 EST 2012
Heat shock protein 70/peptide complexes: potent mediators for the generation of antiviral T cells particularly with regard to low precursor frequencies.
Journal of translational medicine
Tischer S,Basila M,Maecker-Kolhoff B,Immenschuh S,Oelke M,Blasczyk R,Eiz-Vesper B
Wed Oct 12 00:00:00 EDT 2011
Differentiation of chronic lymphocytic leukemia B cells into immunoglobulin secreting cells decreases LEF-1 expression.
PloS one
Gutierrez A,Arendt BK,Tschumper RC,Kay NE,Zent CS,Jelinek DF
Mon Feb 13 00:00:00 EST 2012
Cell docking, movement and cell-cell interactions of heterogeneous cell suspensions in a cell manipulation microdevice.
Sensors (Basel, Switzerland)
Lai FL,Wang YH,Chung YW,Hwang SM,Huang LS
Tue Jun 05 00:00:00 EDT 2012
Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells.
Journal of neuroinflammation
Dao MA,Tate CC,Aizman I,McGrogan M,Case CC
Fri Oct 07 00:00:00 EDT 2011
IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway.
PloS one
Sammicheli S,Dang VP,Ruffin N,Pham HT,Lantto R,Vivar N,Chiodi F,Rethi B
Mon Aug 27 00:00:00 EDT 2012
Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8+ suppressor T cells.
PloS one
Yu Y,Zitzner JR,Houlihan J,Herrera N,Xu L,Miller J,Mathew JM,Tambur AR,Luo X
Mon Aug 27 00:00:00 EDT 2012
Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses.
PloS one
Chiang CL,Hagemann AR,Leskowitz R,Mick R,Garrabrant T,Czerniecki BJ,Kandalaft LE,Powell DJ,Coukos G
Mon Aug 27 00:00:00 EDT 2012
