Product References
More than neutrophils: Lin(+)Ly6G(+)IL-5Rα(+) multipotent myeloid cells (MMCs) are dominant in normal murine bone marrow and retain capacity to differentiate into eosinophils and monocytes.
Journal of leukocyte biology
Jeong BM,Walker MT,Rodriguez R,Coden ME,Nagasaka R,Doan TC,Politanska Y,Abdala-Valencia H,Berdnikovs S
200-05 was used in In vitro experiments to discover an unexpected hematopoietic flexibility of a dominant population of multipotent myeloid cells, typically categorized as neutrophils, but with the previously unknown plasticity to contribute to mature pools of eosinophils and monocytes.
Sat Jan 01 00:00:00 EST 2022
Identification of Keratinocyte Mitogens: Implications for Hyperproliferation in Psoriasis and Atopic Dermatitis.
JID innovations : skin science from molecules to population health
Niehues H,Rikken G,van Vlijmen-Willems IMJJ,Rodijk-Olthuis D,van Erp PEJ,Zeeuwen PLJM,Schalkwijk J,van den Bogaard EH
200-05 was used in In vitro experiments to investigate the mitogens involved in keratinocyte proliferation and stratification.
Sat Jan 01 00:00:00 EST 2022
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
The Journal of experimental medicine
Pieters T,T'Sas S,Vanhee S,Almeida A,Driege Y,Roels J,Van Loocke W,Daneels W,Baens M,Marchand A,Van Trimpont M,Matthijssens F,Morscio J,Lemeire K,Lintermans B,Reunes L,Chaltin P,Offner F,Van Dorpe J,Hochepied T,Berx G,Beyaert R,Staal J,Van Vlierberghe P,Goossens S
Mon Oct 04 00:00:00 EDT 2021
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes.
Nature communications
Renner K,Schwittay T,Chaabane S,Gottschling J,Müller C,Tiefenböck C,Salewski JN,Winter F,Buchtler S,Balam S,Malfertheiner MV,Lubnow M,Lunz D,Graf B,Hitzenbichler F,Hanses F,Poeck H,Kreutz M,Orsó E,Burkhardt R,Niedermair T,Brochhausen C,Gessner A,Salzberger B,Mack M
Fri May 21 00:00:00 EDT 2021
Microfilariae Trigger Eosinophil Extracellular DNA Traps in a Dectin-1-Dependent Manner.
Cell reports
Ehrens A,Lenz B,Neumann AL,Giarrizzo S,Reichwald JJ,Frohberger SJ,Stamminger W,Buerfent BC,Fercoq F,Martin C,Kulke D,Hoerauf A,Hübner MP
Tue Jan 12 00:00:00 EST 2021
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics.
Nature communications
Velten L,Story BA,Hernández-Malmierca P,Raffel S,Leonce DR,Milbank J,Paulsen M,Demir A,Szu-Tu C,Frömel R,Lutz C,Nowak D,Jann JC,Pabst C,Boch T,Hofmann WK,Müller-Tidow C,Trumpp A,Haas S,Steinmetz LM
Mon Mar 01 00:00:00 EST 2021
A comprehensive single cell transcriptional landscape of human hematopoietic progenitors.
Nature communications
Pellin D,Loperfido M,Baricordi C,Wolock SL,Montepeloso A,Weinberg OK,Biffi A,Klein AM,Biasco L
Mon Jun 03 00:00:00 EDT 2019
Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors.
Blood
Dahlin JS,Malinovschi A,Öhrvik H,Sandelin M,Janson C,Alving K,Hallgren J
Thu Jan 28 00:00:00 EST 2016
Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.
Journal of immunology (Baltimore, Md. : 1950)
Pazdrak K,Straub C,Maroto R,Stafford S,White WI,Calhoun WJ,Kurosky A
Tue Nov 15 00:00:00 EST 2016
Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.
The Journal of experimental medicine
Jenkins MR,Rudd-Schmidt JA,Lopez JA,Ramsbottom KM,Mannering SI,Andrews DM,Voskoboinik I,Trapani JA
Mon Mar 09 00:00:00 EDT 2015
Cytokine-stimulated Phosphoflow of PBMC Using CyTOF Mass Cytometry.
Bio-protocol
Fernandez R,Maecker H
200-05 was used in Cell Culture to use phosphoprotein-specific antibodies with flow cytometry to study the level of phosphorylation of intracellular proteins in response to stimulation by cytokines, and use this process to gain insight to the status of the immune system.
Fri Jun 05 00:00:00 EDT 2015
TGF-β-inducible microRNA-183 silences tumor-associated natural killer cells.
Proceedings of the National Academy of Sciences of the United States of America
Donatelli SS,Zhou JM,Gilvary DL,Eksioglu EA,Chen X,Cress WD,Haura EB,Schabath MB,Coppola D,Wei S,Djeu JY
Tue Mar 18 00:00:00 EDT 2014
Eosinophils regulate peripheral B cell numbers in both mice and humans.
Journal of immunology (Baltimore, Md. : 1950)
Wong TW,Doyle AD,Lee JJ,Jelinek DF
Tue Apr 15 00:00:00 EDT 2014
Peptide library-based evaluation of T-cell receptor breadth detects defects in global and regulatory activation in human immunologic diseases.
Proceedings of the National Academy of Sciences of the United States of America
Barber JS,Yokomizo LK,Sheikh V,Freeman AF,Garabedian E,van Dijk E,Sokolic R,Candotti F,Weng NP,Sereti I,Milner JD
Tue May 14 00:00:00 EDT 2013
Adam8 limits the development of allergic airway inflammation in mice.
Journal of immunology (Baltimore, Md. : 1950)
Knolle MD,Nakajima T,Hergrueter A,Gupta K,Polverino F,Craig VJ,Fyfe SE,Zahid M,Permaul P,Cernadas M,Montano G,Tesfaigzi Y,Sholl L,Kobzik L,Israel E,Owen CA
Sat Jun 15 00:00:00 EDT 2013
Rapid and unidirectional perforin pore delivery at the cytotoxic immune synapse.
Journal of immunology (Baltimore, Md. : 1950)
Lopez JA,Jenkins MR,Rudd-Schmidt JA,Brennan AJ,Danne JC,Mannering SI,Trapani JA,Voskoboinik I
Sun Sep 01 00:00:00 EDT 2013
Monocyte-derived IL-5 reduces TNF production by Mycobacterium tuberculosis-specific CD4 T cells during SIV/M. tuberculosis coinfection.
Journal of immunology (Baltimore, Md. : 1950)
Diedrich CR,Mattila JT,Flynn JL
Sat Jun 15 00:00:00 EDT 2013
The IL-7Rα pathway is quantitatively and functionally altered in CD8 T cells in multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950)
Kreft KL,Verbraak E,Wierenga-Wolf AF,van Meurs M,Oostra BA,Laman JD,Hintzen RQ
Wed Feb 15 00:00:00 EST 2012
Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells.
Nature protocols
Choi KD,Vodyanik M,Slukvin II
200-05 was used in Cell Culture to study how differentiation of myeloid progenitors into mature myeloid cells requires an additional 5-19 d of culture with cytokines, depending on the cell type.
Tue Mar 01 00:00:00 EST 2011
Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells.
Nature protocols
Choi KD,Vodyanik M,Slukvin II
200-05 was used in Cell Culture to study how differentiation of myeloid progenitors into mature myeloid cells requires an additional 5-19 d of culture with cytokines, depending on the cell type.
Tue Mar 01 00:00:00 EST 2011
Priming of eosinophils by GM-CSF is mediated by protein kinase CbetaII-phosphorylated L-plastin.
Journal of immunology (Baltimore, Md. : 1950)
Pazdrak K,Young TW,Straub C,Stafford S,Kurosky A
Wed Jun 01 00:00:00 EDT 2011
GCS-100, a novel galectin-3 antagonist, modulates MCL-1, NOXA, and cell cycle to induce myeloma cell death.
Blood
Streetly MJ,Maharaj L,Joel S,Schey SA,Gribben JG,Cotter FE
Thu May 13 00:00:00 EDT 2010
Eosinophil differentiation in the bone marrow is inhibited by T cell-derived IFN-gamma.
Blood
de Bruin AM,Buitenhuis M,van der Sluijs KF,van Gisbergen KP,Boon L,Nolte MA
Thu Oct 07 00:00:00 EDT 2010
Hypoxia modulates human eosinophil function.
Clinical and molecular allergy : CMA
Nissim Ben Efraim AH,Eliashar R,Levi-Schaffer F
Mon Jul 19 00:00:00 EDT 2010
Regulation of myelopoiesis through syntenin-mediated modulation of IL-5 receptor output.
Blood
Beekman JM,Verhagen LP,Geijsen N,Coffer PJ
Thu Oct 29 00:00:00 EDT 2009
TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins.
Blood
Driss V,Legrand F,Hermann E,Loiseau S,Guerardel Y,Kremer L,Adam E,Woerly G,Dombrowicz D,Capron M
Thu Apr 02 00:00:00 EDT 2009
trans-Resveratrol, an extract of red wine, inhibits human eosinophil activation and degranulation.
British journal of pharmacology
Tan Y,Lim LH
Mon Dec 01 00:00:00 EST 2008
Prostaglandin E2 inhibits eosinophil trafficking through E-prostanoid 2 receptors.
Journal of immunology (Baltimore, Md. : 1950)
Sturm EM,Schratl P,Schuligoi R,Konya V,Sturm GJ,Lippe IT,Peskar BA,Heinemann A
Sat Nov 15 00:00:00 EST 2008
Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Sakuishi K,Oki S,Araki M,Porcelli SA,Miyake S,Yamamura T
Sat Sep 15 00:00:00 EDT 2007
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils.
Blood
Munitz A,Bachelet I,Eliashar R,Moretta A,Moretta L,Levi-Schaffer F
Wed Mar 01 00:00:00 EST 2006
Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation.
Journal of immunology (Baltimore, Md. : 1950)
van Beek J,van Meurs M,'t Hart BA,Brok HP,Neal JW,Chatagner A,Harris CL,Omidvar N,Morgan BP,Laman JD,Gasque P
Tue Feb 15 00:00:00 EST 2005
IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression.
Journal of immunology (Baltimore, Md. : 1950)
Ferland C,Flamand N,Davoine F,Chakir J,Laviolette M
Fri Oct 01 00:00:00 EDT 2004
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research
Hemminki A,Kanerva A,Liu B,Wang M,Alvarez RD,Siegal GP,Curiel DT
Sat Feb 15 00:00:00 EST 2003
