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Highest antigen sequence indentity to the following orthologs: Mouse (32%), Rat (32%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-140161. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. L-Myc gene ontology annotations include DNA binding function, DNA-binding transcription factor activity, RNA polymerase II-specific action, protein dimerization activity, and regulation of inner ear auditory receptor cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHe38; Class E basic helix-loop-helix protein 38; l-myc-1 proto-oncogene; myc-related gene from lung cancer; Protein L-Myc; Protein L-Myc-1; V-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived
Gene Aliases: BHLHE38; L-Myc; LMYC; MYCL; MYCL1
UniProt ID: (Human) P12524
Entrez Gene ID: (Human) 4610
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