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Highest antigen sequence indentity to the following orthologs: Mouse (78%), Rat (78%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55848. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The leiomodin 1 protein (LMOD1) has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy. The leiomodin 1 protein has a putative membrane-spanning region and 2 types of tandemly repeated blocks. The transcript is expressed in all tissues tested, with the highest levels in thyroid, eye muscle, skeletal muscle, and ovary. Increased expression of leiomodin 1 may be linked to Graves' disease and thyroid-associated ophthalmopathy.
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Protein Aliases: 64 kDa autoantigen 1D; 64 kDa autoantigen 1D3; 64 kDa autoantigen D1; leimodin 1 (smooth muscle); leiomodin 1 (smooth muscle); Leiomodin, muscle form; Leiomodin-1; SM-Lmod; Smooth muscle leiomodin; thyroid and eye muscle autoantigen D1 (64kD); Thyroid-associated ophthalmopathy autoantigen
Gene Aliases: 1D; 64kD; D1; LMOD1; SM-LMOD; SMLMOD
UniProt ID: (Human) P29536
Entrez Gene ID: (Human) 25802
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