Product References
Automating Human Induced Pluripotent Stem Cell Culture and Differentiation of iPSC-Derived Retinal Pigment Epithelium for Personalized Drug Testing.
SLAS technology
Truong V,Viken K,Geng Z,Barkan S,Johnson B,Ebeling MC,Montezuma SR,Ferrington DA,Dutton JR
AF-120-14E was used in Cell Culture to demonstrate scalable, reproducible culture and differentiation of hiPSC lines from individuals on the TECAN Fluent platform and illustrate the potential for end-to-end automation of hiPSC-based personalized drug testing.
Tue Jun 01 00:00:00 EDT 2021
Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes.
Nature communications
Sugishita H,Kondo T,Ito S,Nakayama M,Yakushiji-Kaminatsui N,Kawakami E,Koseki Y,Ohinata Y,Sharif J,Harachi M,Blackledge NP,Klose RJ,Koseki H
Thu Sep 09 00:00:00 EDT 2021
CD82 is a marker to isolate β cell precursors from human iPS cells and plays a role for the maturation of β cells.
Scientific reports
Watanabe A,Tanaka A,Koga C,Matsumoto M,Okazaki Y,Kin T,Miyajima A
Wed May 05 00:00:00 EDT 2021
LSD1 inhibition yields functional insulin-producing cells from human embryonic stem cells.
Stem cell research & therapy
He F,Li N,Huang HB,Wang JB,Yang XF,Wang HD,Huang W,Li FR
AF-120-14E was used in Cell Culture to investigate the role of LSD1 on insulin production from human embryonic stem cell line H9.
Tue Apr 28 00:00:00 EDT 2020
The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis.
Scientific reports
Griffiths R,Woods S,Cheng A,Wang P,Griffiths-Jones S,Ronshaugen M,Kimber SJ
Mon Mar 16 00:00:00 EDT 2020
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.
Nature communications
Boon R,Kumar M,Tricot T,Elia I,Ordovas L,Jacobs F,One J,De Smedt J,Eelen G,Bird M,Roelandt P,Doglioni G,Vriens K,Rossi M,Vazquez MA,Vanwelden T,Chesnais F,El Taghdouini A,Najimi M,Sokal E,Cassiman D,Snoeys J,Monshouwer M,Hu WS,Lange C,Carmeliet P,Fendt SM,Verfaillie CM
Fri Mar 13 00:00:00 EDT 2020
Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2.
Cell death & disease
Li J,Yang Y,Fan J,Xu H,Fan L,Li H,Zhao RC
Mon Jun 24 00:00:00 EDT 2019
Exosomes Derived from Human Induced Pluripotent Stem Cells-Endothelia Cells Promotes Postnatal Angiogenesis in Mice Bearing Ischemic Limbs.
International journal of biological sciences
Ye M,Ni Q,Qi H,Qian X,Chen J,Guo X,Li M,Zhao Y,Xue G,Deng H,Zhang L
AF-120-14E was used in In vitro experiments to demonstrate exosomes derived from hiPS-ECs expressing miR-199b-5p promote angiogenesis in a mouse model bearing ischemic limbs through Jagged-1-dependent upregulation of VEGFR2 in HUVECs.
Mon Dec 16 00:00:00 EST 2019
Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents.
PloS one
Southard SM,Kotipatruni RP,Rust WL
AF-120-14E was used in Cell Culture to show that SR1423 is a candidate cell line for the production of insulin-producing cells useful for the treatment of diabetes.
Thu Feb 21 00:00:00 EST 2019
Long Noncoding RNA uc001pwg.1 Is Downregulated in Neointima in Arteriovenous Fistulas and Mediates the Function of Endothelial Cells Derived from Pluripotent Stem Cells.
Stem cells international
Lv L,Qi H,Guo X,Ni Q,Yan Z,Zhang L
AF-120-14E was used in In vitro experiments to represent the first effort of identifying a novel candidate lncRNA for modulating the function of iPSC-ECs, which may facilitate the improvement of stem cell-based therapies for AVF failure.
Tue Sep 29 00:00:00 EDT 2020
Methanobactin reverses acute liver failure in a rat model of Wilson disease.
The Journal of clinical investigation
Lichtmannegger J,Leitzinger C,Wimmer R,Schmitt S,Schulz S,Kabiri Y,Eberhagen C,Rieder T,Janik D,Neff F,Straub BK,Schirmacher P,DiSpirito AA,Bandow N,Baral BS,Flatley A,Kremmer E,Denk G,Reiter FP,Hohenester S,Eckardt-Schupp F,Dencher NA,Adamski J,Sauer V,Niemietz C,Schmidt HH,Merle U,Gotthardt DN,Kroemer G,Weiss KH,Zischka H
Fri Jul 01 00:00:00 EDT 2016
Restoring Ureagenesis in Hepatocytes by CRISPR/Cas9-mediated Genomic Addition to Arginase-deficient Induced Pluripotent Stem Cells.
Molecular therapy. Nucleic acids
Lee PC,Truong B,Vega-Crespo A,Gilmore WB,Hermann K,Angarita SA,Tang JK,Chang KM,Wininger AE,Lam AK,Schoenberg BE,Cederbaum SD,Pyle AD,Byrne JA,Lipshutz GS
Tue Nov 29 00:00:00 EST 2016
Role of SOX17 in hematopoietic development from human embryonic stem cells.
Blood
Nakajima-Takagi Y,Osawa M,Oshima M,Takagi H,Miyagi S,Endoh M,Endo TA,Takayama N,Eto K,Toyoda T,Koseki H,Nakauchi H,Iwama A
Thu Jan 17 00:00:00 EST 2013
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Nature
Mansour AA,Gafni O,Weinberger L,Zviran A,Ayyash M,Rais Y,Krupalnik V,Zerbib M,Amann-Zalcenstein D,Maza I,Geula S,Viukov S,Holtzman L,Pribluda A,Canaani E,Horn-Saban S,Amit I,Novershtern N,Hanna JH
Thu Aug 16 00:00:00 EDT 2012
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Kajiwara M,Aoi T,Okita K,Takahashi R,Inoue H,Takayama N,Endo H,Eto K,Toguchida J,Uemoto S,Yamanaka S
Tue Jul 31 00:00:00 EDT 2012
Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal.
Proceedings of the National Academy of Sciences of the United States of America
Przybyla LM,Voldman J
Tue Jan 17 00:00:00 EST 2012
The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A.
Journal of immunology (Baltimore, Md. : 1950)
Escribese MM,Sierra-Filardi E,Nieto C,Samaniego R,Sánchez-Torres C,Matsuyama T,Calderon-Gómez E,Vega MA,Salas A,Sánchez-Mateos P,Corbí AL
Wed Aug 15 00:00:00 EDT 2012
Redifferentiation of expanded human pancreatic β-cell-derived cells by inhibition of the NOTCH pathway.
The Journal of biological chemistry
Bar Y,Russ HA,Sintov E,Anker-Kitai L,Knoller S,Efrat S
Fri May 18 00:00:00 EDT 2012
Dedifferentiation of foetal CNS stem cells to mesendoderm-like cells through an EMT process.
PloS one
Ber S,Lee C,Voiculescu O,Surani MA
Mon Jun 04 00:00:00 EDT 2012
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency.
Aging
Ohmine S,Squillace KA,Hartjes KA,Deeds MC,Armstrong AS,Thatava T,Sakuma T,Terzic A,Kudva Y,Ikeda Y
Sun Jan 01 00:00:00 EST 2012
Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc.
International journal of molecular sciences
Chang HM,Liao YW,Chiang CH,Chen YJ,Lai YH,Chang YL,Chen HL,Jeng SY,Hsieh JH,Peng CH,Li HY,Chien Y,Chen SY,Chen LK,Huo TI
Mon Aug 31 00:00:00 EDT 2015
Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells.
PloS one
Rodríguez-Martínez G,Molina-Hernández A,Velasco I
Tue Jan 29 00:00:00 EST 2013
PTK7 marks the first human developmental EMT in vitro.
PloS one
Chan DN,Azghadi SF,Feng J,Lowry WE
Mon Jun 24 00:00:00 EDT 2013
Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells.
Scientific reports
Umeda K,Zhao J,Simmons P,Stanley E,Elefanty A,Nakayama N
Mon Feb 25 00:00:00 EST 2013
TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages.
PloS one
Bourlier V,Sengenès C,Zakaroff-Girard A,Decaunes P,Wdziekonski B,Galitzky J,Villageois P,Esteve D,Chiotasso P,Dani C,Bouloumié A
Mon Jun 18 00:00:00 EDT 2012
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells.
Cell
Hayashi K,Ohta H,Kurimoto K,Aramaki S,Saitou M
Fri Aug 19 00:00:00 EDT 2011
A poised chromatin platform for TGF-β access to master regulators.
Cell
Xi Q,Wang Z,Zaromytidou AI,Zhang XH,Chow-Tsang LF,Liu JX,Kim H,Barlas A,Manova-Todorova K,Kaartinen V,Studer L,Mark W,Patel DJ,Massagué J
Fri Dec 23 00:00:00 EST 2011
Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells.
Stem cells (Dayton, Ohio)
Iacovino M,Bosnakovski D,Fey H,Rux D,Bajwa G,Mahen E,Mitanoska A,Xu Z,Kyba M
Sat Oct 01 00:00:00 EDT 2011
Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages.
Stem cells (Dayton, Ohio)
Liang YJ,Yang BC,Chen JM,Lin YH,Huang CL,Cheng YY,Hsu CY,Khoo KH,Shen CN,Yu J
Thu Dec 01 00:00:00 EST 2011
Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro.
PloS one
Russ HA,Sintov E,Anker-Kitai L,Friedman O,Lenz A,Toren G,Farhy C,Pasmanik-Chor M,Oron-Karni V,Ravassard P,Efrat S
Mon Mar 05 00:00:00 EST 2012
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.
Cell research
Song Z,Cai J,Liu Y,Zhao D,Yong J,Duo S,Song X,Guo Y,Zhao Y,Qin H,Yin X,Wu C,Che J,Lu S,Ding M,Deng H
Sun Nov 01 00:00:00 EDT 2009
