Product References
Reduced Cell-ECM Interactions in the EpiSC Colony Center Cause Heterogeneous Differentiation.
Cells
Amar K,Saha S,Debnath A,Weng CH,Roy A,Han KY,Chowdhury F
120-14E was used in Cell Culture to demonstrate a biophysical regulation of heterogeneous EpiSC colony differentiation.
Sun Jan 15 00:00:00 EST 2023
Acute liver steatosis translationally controls the epigenetic regulator MIER1 to promote liver regeneration in a study with male mice.
Nature communications
Chen Y,Chen L,Wu X,Zhao Y,Wang Y,Jiang D,Liu X,Zhou T,Li S,Wei Y,Liu Y,Hu C,Zhou B,Qin J,Ying H,Ding Q
120-14E was used in In vitro experiments to identify an epigenetic mechanism by which the early phase lipid redistribution from adipose tissue to liver during regeneration impacts hepatocyte proliferation, and suggest a potential strategy to boost liver regeneration.
Sat Mar 18 00:00:00 EDT 2023
Protocol to generate cardiac pericytes from human induced pluripotent stem cells.
STAR protocols
Shen M,Zhao SR,Khokhar Y,Li L,Zhou Y,Liu C,Wu JC
120-14E was used in Cell Culture to present a protocol to generate them from human induced pluripotent stem cells (hiPSCs).
Thu Apr 27 00:00:00 EDT 2023
LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells.
Viruses
Zhang L,Bisht P,Flamier A,Barrasa MI,Friesen M,Richards A,Hughes SH,Jaenisch R
120-14E was used in Cell Culture to conclude that retrotransposition in virus-infected cells, in contrast to transfected cells, may be facilitated because virus infection, in contrast to viral RNA transfection, results in significantly higher viral RNA levels and stimulates LINE1 expression by causing cellular stress.
Sat Feb 25 00:00:00 EST 2023
Derivation and Primordial Germ Cell Induction of Intermediate Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Yu L,Ballard E,Pinzon Arteaga CA,Wu J
120-14E was used in Cell Culture to describe the method for derivation and maintenance of mouse and human FTW-PSCs, as well as PGC-LC induction from FTW-PSCs.
Fri Jul 21 00:00:00 EDT 2023
Tracking the dynamics of female germ cell development during peri-hatch periods using a gene-edited chicken model.
Poultry science
Pu L,Xie L,Chen J,Sun H,Huang Z,Xu T,Tian K,Zhong J,Xu H,Liu X,Lu Y
120-14E was used in In vitro experiments to provide evidence for further exploration of the underlying mechanism and serve as a reference for chicken breeding and management.
Wed Mar 01 00:00:00 EST 2023
Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function.
Journal of neuroinflammation
Konstantinidis E,Portal B,Mothes T,Beretta C,Lindskog M,Erlandsson A
120-14E was used in Cell Culture to demonstrate that inclusions of aggregated Aβ affect the reactive state of the astrocytes, as well as their ability to support neuronal function.
Tue Jan 03 00:00:00 EST 2023
Dissecting peri-implantation development using cultured human embryos and embryo-like assembloids.
Cell research
Ai Z,Niu B,Yin Y,Xiang L,Shi G,Duan K,Wang S,Hu Y,Zhang C,Zhang C,Rong L,Kong R,Chen T,Guo Y,Liu W,Li N,Zhao S,Zhu X,Mai X,Li Y,Wu Z,Zheng Y,Fu J,Ji W,Li T
120-14E was used in Cell Culture to provide insights into human peri-implantation development, and the E-assembloid offers a useful model to disentangle cellular behaviors and signaling interactions that drive human embryogenesis.
Fri Sep 01 00:00:00 EDT 2023
Directed Differentiation of Human iPSCs into Microglia-Like Cells Using Defined Transcription Factors.
Methods in molecular biology (Clifton, N.J.)
Chen SW,Wong YH
120-14E was used in Cell Culture to provide a stepwise protocol for the simple, robust, and efficient differentiation of hiPSCs into microglia-like cells (iMGs) by overexpression of SPI1 and CEBPA.
Mon Jun 12 00:00:00 EDT 2023
Enhanced cultivation of chicken primordial germ cells.
Scientific reports
Dehdilani N,Yousefi Taemeh S,Rival-Gervier S,Montillet G,Kress C,Jean C,Goshayeshi L,Dehghani H,Pain B
120-14E was used in Cell Culture to highlight the importance of choosing an appropriate culture medium for cPGCs growth and expansion.
Sat Jul 29 00:00:00 EDT 2023
Derivation of Human Extraembryonic Mesoderm-like Cells from Primitive Endoderm.
International journal of molecular sciences
Farkas K,Ferretti E
120-14E was used in In vitro experiments to find that the ExM-like cells clustered with the LUM/ANXA1-rich cell populations of the gastrulating embryo, indicating similarity between in vitro and ex utero cell populations.
Wed Jul 12 00:00:00 EDT 2023
Generation and characterization of stable pig pregastrulation epiblast stem cell lines.
Cell research
Zhi M,Zhang J,Tang Q,Yu D,Gao S,Gao D,Liu P,Guo J,Hai T,Gao J,Cao S,Zhao Z,Li C,Weng X,He M,Chen T,Wang Y,Long K,Jiao D,Li G,Zhang J,Liu Y,Lin Y,Pang D,Zhu Q,Chen N,Huang J,Chen X,Yao Y,Yang J,Xie Z,Huang X,Liu M,Zhang R,Li Q,Miao Y,Tian J,Huang X,Ouyang H,Liu B,Xie W,Zhou Q,Wei H,Liu Z,Zheng C,Li M,Han J
Fri Apr 01 00:00:00 EDT 2022
Parallel functional assessment of m6A sites in human endodermal differentiation with base editor screens.
Nature communications
Cheng W,Liu F,Ren Z,Chen W,Chen Y,Liu T,Ma Y,Cao N,Wang J
120-14E was used in Cell Culture to develop an adenine base editor-based strategy to systematically identify functional N6-methyladenosine sites that control lineage decisions of human embryonic stem cells.
Tue Jan 25 00:00:00 EST 2022
Serum-Free Production of Three-Dimensional Hepatospheres from Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.)
Rashidi H,Hay DC
120-14E was used in In vitro experiments to describe a methodology to generate 3D hepatospheres from human pluripotent stem cells using defined and commercially available reagents.
Thu Jun 23 00:00:00 EDT 2022
Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium.
Bioengineering (Basel, Switzerland)
Faynus MA,Bailey JK,Pennington BO,Katsura M,Proctor DA,Yeh AK,Menon S,Choi DG,Lebkowski JS,Johnson LV,Clegg DO
120-14E was used in Cell Culture to investigate treatment options for dry age-related macular degeneration via organoids.
Mon Jul 04 00:00:00 EDT 2022
Comparing the mitochondrial signatures in ESCs and iPSCs and their neural derivations.
Cell cycle (Georgetown, Tex.)
Kristiansen CK,Chen A,Høyland LE,Ziegler M,Sullivan GJ,Bindoff LA,Liang KX
120-14E was used in Cell Culture to show that while ESCs and iPSCs are similar at the pluripotent stage, differences in mitochondrial function may develop during differentiation and must be taken into account when extrapolating results from different cell types.
Sat Oct 01 00:00:00 EDT 2022
Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.
Cell reports
Devoucoux M,Fort V,Khelifi G,Xu J,Alerasool N,Galloy M,Wong N,Bourriquen G,Fradet-Turcotte A,Taipale M,Hope K,Hussein SMI,Côté J
120-14E was used in In vitro experiments to indicate that the ZMYND11-MBTD1 fusion functions primarily by mistargeting the NuA4/TIP60 complex to the body of genes, altering normal transcription of specific genes, likely driving oncogenesis in part through the Myc regulatory network.
Tue Jun 14 00:00:00 EDT 2022
Stiffness of primordial germ cells is required for their extravasation in avian embryos.
iScience
Saito D,Tadokoro R,Nagasaka A,Yoshino D,Teramoto T,Mizumoto K,Funamoto K,Kidokoro H,Miyata T,Tamura K,Takahashi Y
120-14E was used in Cell Culture to demonstrate with single-cell level live-imaging analyses that the PGCs are arrested at a specific site in the capillary plexus, which is predominantly governed by occlusion at a narrow path in the vasculature.
Thu Dec 22 00:00:00 EST 2022
Cell Surface Mechanics Gate Embryonic Stem Cell Differentiation.
Cell stem cell
Bergert M,Lembo S,Sharma S,Russo L,Milovanović D,Gretarsson KH,Börmel M,Neveu PA,Hackett JA,Petsalaki E,Diz-Muñoz A
120-14E was used in Cell Culture to show that membrane mechanics gate exit from naive pluripotency of mouse embryonic stem cells.
Thu Feb 04 00:00:00 EST 2021
Principles of signaling pathway modulation for enhancing human naive pluripotency induction.
Cell stem cell
Bayerl J,Ayyash M,Shani T,Manor YS,Gafni O,Massarwa R,Kalma Y,Aguilera-Castrejon A,Zerbib M,Amir H,Sheban D,Geula S,Mor N,Weinberger L,Naveh Tassa S,Krupalnik V,Oldak B,Livnat N,Tarazi S,Tawil S,Wildschutz E,Ashouokhi S,Lasman L,Rotter V,Hanna S,Ben-Yosef D,Novershtern N,Viukov S,Hanna JH
Thu Sep 02 00:00:00 EDT 2021
The forkhead transcription factor FOXK2 premarks lineage-specific genes in human embryonic stem cells for activation during differentiation.
Nucleic acids research
Ji Z,Li Y,Liu SX,Sharrocks AD
120-14E was used in Cell Culture to study how enhancer regulatory regions are established during differentiation by studying the genome-wide binding profile of the forkhead transcription factor FOXK2 in human embryonic stem cells (ESCs) and downstream cell types.
Mon Feb 22 00:00:00 EST 2021
Long-term effects of human induced pluripotent stem cell-derived retinal cell transplantation in Pde6b knockout rats.
Experimental & molecular medicine
Yang JM,Chung S,Yun K,Kim B,So S,Kang S,Kang E,Lee JY
Thu Apr 01 00:00:00 EDT 2021
Differentiation of Human Pluripotent Stem Cells Into Definitive Endoderm Cells in Various Flexible Three-Dimensional Cell Culture Systems: Possibilities and Limitations.
Frontiers in cell and developmental biology
Bogacheva MS,Harjumäki R,Flander E,Taalas A,Bystriakova MA,Yliperttula M,Xiang X,Leung AW,Lou YR
120-14E was used in Cell Culture to study the influence of pheroid size and 3D cell culture systems on spheroid morphology and the effectiveness of definitive endoderm (DE) differentiation as assessed by quantitative PCR (qPCR), flow cytometry, immunofluorescence, and computational modeling.
Wed Sep 29 00:00:00 EDT 2021
Bone morphogenetic protein induces bone invasion of melanoma by epithelial-mesenchymal transition via the Smad1/5 signaling pathway.
Laboratory investigation; a journal of technical methods and pathology
Gao J,Muroya R,Huang F,Nagata K,Shin M,Nagano R,Tajiri Y,Fujii S,Yamaza T,Aoki K,Tamura Y,Inoue M,Chishaki S,Kukita T,Okabe K,Matsuda M,Mori Y,Kiyoshima T,Jimi E
Mon Nov 01 00:00:00 EDT 2021
Automating Human Induced Pluripotent Stem Cell Culture and Differentiation of iPSC-Derived Retinal Pigment Epithelium for Personalized Drug Testing.
SLAS technology
Truong V,Viken K,Geng Z,Barkan S,Johnson B,Ebeling MC,Montezuma SR,Ferrington DA,Dutton JR
120-14E was used in Cell Culture to demonstrate scalable, reproducible culture and differentiation of hiPSC lines from individuals on the TECAN Fluent platform and illustrate the potential for end-to-end automation of hiPSC-based personalized drug testing.
Tue Jun 01 00:00:00 EDT 2021
Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion.
iScience
Zhang Y,Guo A,Lyu C,Bi R,Wu Z,Li W,Zhao P,Niu Y,Na J,Xi JJ,Du Y
120-14E was used in Cell Culture to optimize the in vitro liver fibrotic niches and subsequently harvest their bioactive ingredients as niche extracts (NEs) so that pathology-relevant and tissue-specific NEs provide innovative and generalizable strategies for the discovery of optimal cellular niche and bioactive niche compositions.
Fri Nov 19 00:00:00 EST 2021
Synthetic liver fibrotic niche extracts achieve in vitro hepatoblasts phenotype enhancement and expansion.
iScience
Zhang Y,Guo A,Lyu C,Bi R,Wu Z,Li W,Zhao P,Niu Y,Na J,Xi JJ,Du Y
120-14E was used in Cell Culture to optimize the in vitro liver fibrotic niches and subsequently harvest their bioactive ingredients as niche extracts (NEs) so that pathology-relevant and tissue-specific NEs provide innovative and generalizable strategies for the discovery of optimal cellular niche and bioactive niche compositions.
Fri Nov 19 00:00:00 EST 2021
Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells.
The Journal of biological chemistry
Wang X,Wang X,Zhang X,Zhang Y,Zhu Z,Li Y,Zhang M,Ji J,Yu Y,Ye SD
Mon Nov 01 00:00:00 EDT 2021
Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation.
Hepatology (Baltimore, Md.)
Peaslee C,Esteva-Font C,Su T,Munoz-Howell A,Duwaerts CC,Liu Z,Rao S,Liu K,Medina M,Sneddon JB,Maher JJ,Mattis AN
120-14E was used in In vitro experiments to test this protocol in >70 iPSC lines, 90% of which consistently formed complete sheets of endoderm.
Fri Oct 01 00:00:00 EDT 2021
Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells.
Pharmaceuticals (Basel, Switzerland)
Bogacheva MS,Bystriakova MA,Lou YR
120-14E was used in Sample Preparation (Western Blotting) to investigate hepatocyte-like cell culture from induced pluripotent stem cells for future therapeutic treatment.
Mon Jun 07 00:00:00 EDT 2021
Thyroid Hormone Effect on the Differentiation of Human Induced Pluripotent Stem Cells into Hepatocyte-Like Cells.
Pharmaceuticals (Basel, Switzerland)
Bogacheva MS,Bystriakova MA,Lou YR
120-14E was used in Sample Preparation (Western Blotting) to investigate hepatocyte-like cell culture from induced pluripotent stem cells for future therapeutic treatment.
Mon Jun 07 00:00:00 EDT 2021
Angiopoietins stimulate pancreatic islet development from stem cells.
Scientific reports
Karanth SS,Sun S,Bi H,Ye K,Jin S
Wed Jun 30 00:00:00 EDT 2021
Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells.
Nature communications
Liu H,Li R,Liao HK,Min Z,Wang C,Yu Y,Shi L,Dan J,Hayek A,Martinez Martinez L,Nuñez Delicado E,Izpisua Belmonte JC
Mon Jun 07 00:00:00 EDT 2021
SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis.
Cell reports
Jung HS,Uenishi G,Park MA,Liu P,Suknuntha K,Raymond M,Choi YJ,Thomson JA,Ong IM,Slukvin II
120-14E was used in In vitro experiments to investigate the role and mechanisms of SOX17 in human pluripotent stem cells.
Tue Feb 16 00:00:00 EST 2021
Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes.
STAR protocols
Sinton MC,Meseguer-Ripolles J,Lucendo-Villarin B,Drake AJ,Hay DC
120-14E was used in Cell Culture to evaluate hepatocyte-like cell manufacturing from human pluripotent stem cells to study hepatic steatosis.
Fri Jun 18 00:00:00 EDT 2021
A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion.
Nature communications
Gonçalves CA,Larsen M,Jung S,Stratmann J,Nakamura A,Leuschner M,Hersemann L,Keshara R,Perlman S,Lundvall L,Thuesen LL,Hare KJ,Amit I,Jørgensen A,Kim YH,Del Sol A,Grapin-Botton A
Tue May 25 00:00:00 EDT 2021
Cultivation and characterization of primordial germ cells from blue layer hybrids (Araucana crossbreeds) and generation of germline chimeric chickens.
Scientific reports
Altgilbers S,Klein S,Dierks C,Weigend S,Kues WA
Mon Jun 21 00:00:00 EDT 2021
Loss of Resf1 reduces the efficiency of embryonic stem cell self-renewal and germline entry.
Life science alliance
Vojtek M,Chambers I
120-14E was used in Cell Culture to investigate retroelement silencing factor 1 regulation in embryonic stem cells.
Wed Dec 01 00:00:00 EST 2021
Serine biosynthesis defect due to haploinsufficiency of PHGDH causes retinal disease.
Nature metabolism
Eade K,Gantner ML,Hostyk JA,Nagasaki T,Giles S,Fallon R,Harkins-Perry S,Baldini M,Lim EW,Scheppke L,Dorrell MI,Cai C,Baugh EH,Wolock CJ,Wallace M,Berlow RB,Goldstein DB,Metallo CM,Friedlander M,Allikmets R
120-14E was used in Cell Culture to identify a rare , functional variants in the gene encoding the rate-limiting serine biosynthetic enzyme, phosphoglycerate dehydrogenase (PHGDH), as the single locus accounting for a significant fraction of Macular telangiectasia type 2 (MacTel) to suggest a number of potential treatment options.
Mon Mar 01 00:00:00 EST 2021
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
The Journal of clinical investigation
Oppezzo A,Bourseguin J,Renaud E,Pawlikowska P,Rosselli F
120-14E was used in Cell Culture to the impact of the constitutive activation of stress signaling pathways on hematopoietic stem cell maintenance and function in Fanconi anemia.
Mon Mar 02 00:00:00 EST 2020
Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia.
The Journal of clinical investigation
Oppezzo A,Bourseguin J,Renaud E,Pawlikowska P,Rosselli F
120-14E was used in Cell Culture to the impact of the constitutive activation of stress signaling pathways on hematopoietic stem cell maintenance and function in Fanconi anemia.
Mon Mar 02 00:00:00 EST 2020
Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations.
EMBO molecular medicine
Liang KX,Kristiansen CK,Mostafavi S,Vatne GH,Zantingh GA,Kianian A,Tzoulis C,Høyland LE,Ziegler M,Perez RM,Furriol J,Zhang Z,Balafkan N,Hong Y,Siller R,Sullivan GJ,Bindoff LA
Wed Oct 07 00:00:00 EDT 2020
Coordination of germ layer lineage choice by TET1 during primed pluripotency.
Genes & development
Luo X,van der Veer BK,Sun L,Bartoccetti M,Boretto M,Vankelecom H,Khoueiry R,Koh KP
120-14E was used in Cell Culture to study how Tet1 plays a pivotal role upstream of germ layer lineage bifurcation and provide mechanistic information for epigenetic integration of pluripotency and signal-induced differentiation cues.
Wed Apr 01 00:00:00 EDT 2020
B3GALT5 knockout alters gycosphingolipid profile and facilitates transition to human naïve pluripotency.
Proceedings of the National Academy of Sciences of the United States of America
Lin RJ,Kuo MW,Yang BC,Tsai HH,Chen K,Huang JR,Lee YS,Yu AL,Yu J
Tue Nov 03 00:00:00 EST 2020
Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c-kit+ cardiac interstitial cells.
Stem cells translational medicine
Wang BJ,Alvarez R,Muliono A,Sengphanith S,Monsanto MM,Weeks J,Sacripanti R,Sussman MA
120-14E was used in Cell Culture to investigate cardiac interstitial cell transcriptome in the heart.
Fri May 01 00:00:00 EDT 2020
Adaptation within embryonic and neonatal heart environment reveals alternative fates for adult c-kit+ cardiac interstitial cells.
Stem cells translational medicine
Wang BJ,Alvarez R,Muliono A,Sengphanith S,Monsanto MM,Weeks J,Sacripanti R,Sussman MA
120-14E was used in Cell Culture to investigate cardiac interstitial cell transcriptome in the heart.
Fri May 01 00:00:00 EDT 2020
Live-cell screening platform using human-induced pluripotent stem cells expressing fluorescence-tagged cytochrome P450 1A1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Kim JW,Im I,Kim H,Jeon JS,Kang EH,Jo S,Chun HS,Yoon S,Kim JH,Kim SK,Park HJ
Wed Jul 01 00:00:00 EDT 2020
Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids.
International journal of stem cells
Mun SJ,Hong YH,Ahn HS,Ryu JS,Chung KS,Son MJ
120-14E was used in Cell Culture to test long-term prolonged culture of organoids to increase their maturity to demonstrate that organoids can be exponentially expanded by serial passaging, while maintaining long-term functional maturation potential, hence are a practical and renewable cell source for human cell-based and personalized 3D liver models.
Thu Jul 30 00:00:00 EDT 2020
Development of genetic quality tests for good manufacturing practice-compliant induced pluripotent stem cells and their derivatives.
Scientific reports
Jo HY,Han HW,Jung I,Ju JH,Park SJ,Moon S,Geum D,Kim H,Park HJ,Kim S,Stacey GN,Koo SK,Park MH,Kim JH
Tue Mar 03 00:00:00 EST 2020
Critical Roles of Translation Initiation and RNA Uridylation in Endogenous Retroviral Expression and Neural Differentiation in Pluripotent Stem Cells.
Cell reports
Takahashi K,Jeong D,Wang S,Narita M,Jin X,Iwasaki M,Perli SD,Conklin BR,Yamanaka S
120-14E was used in Cell Culture to investigate NAT1 and eIF4G1 expression in pluripotent stem cells.
Tue Jun 02 00:00:00 EDT 2020
CD140b and CD73 are markers for human induced pluripotent stem cell-derived erythropoietin-producing cells.
FEBS open bio
Nishimoto S,Mizuno T,Takahashi K,Nagano F,Yuzawa Y,Nishiyama A,Osafune K,Hitomi H,Nagamatsu T
Sun Mar 01 00:00:00 EST 2020
Induced pluripotent stem cell-derived tenocyte-like cells promote the regeneration of injured tendons in mice.
Scientific reports
Komura S,Satake T,Goto A,Aoki H,Shibata H,Ito K,Hirakawa A,Yamada Y,Akiyama H
Wed Mar 04 00:00:00 EST 2020
Directed Differentiation of Notochord-like and Nucleus Pulposus-like Cells Using Human Pluripotent Stem Cells.
Cell reports
Zhang Y,Zhang Z,Chen P,Ma CY,Li C,Au TYK,Tam V,Peng Y,Wu R,Cheung KMC,Sham PC,Tse HF,Chan D,Leung VY,Cheah KSE,Lian Q
120-14E was used in Cell Culture to report a protocolfor directed in vitro differentiation of human pluripotent stem cells (hPSCs) into notochord-like and nucleus pulposus (NP)-like cells of the disc.
Tue Feb 25 00:00:00 EST 2020
Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation.
Stem cell reports
Zhang W,Tian Y,Gao Q,Li X,Li Y,Zhang J,Yao C,Wang Y,Wang H,Zhao Y,Zhang Q,Li L,Yu Y,Fan Y,Shuai L
Tue Jul 14 00:00:00 EDT 2020
TGF-β regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells.
Scientific reports
Remšík J,Pícková M,Vacek O,Fedr R,Binó L,Hampl A,Souček K
Thu Jul 09 00:00:00 EDT 2020
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids.
eLife
Renner H,Grabos M,Becker KJ,Kagermeier TE,Wu J,Otto M,Peischard S,Zeuschner D,TsyTsyura Y,Disse P,Klingauf J,Leidel SA,Seebohm G,Schöler HR,Bruder JM
Tue Nov 03 00:00:00 EST 2020
Generation of cortical neurons through large-scale expanding neuroepithelial stem cell from human pluripotent stem cells.
Stem cell research & therapy
Zhao S,Duan K,Ai Z,Niu B,Chen Y,Kong R,Li T
120-14E was used in Cell Culture to develop a serum-free, scalable, low-cost, 3D suspension culture system yielding high-quality NESC-spheres, thereby efficiently generating corticol neurons for cell therapy, disease modelling and drug-screening activities.
Fri Oct 02 00:00:00 EDT 2020
microRNA-181c-5p promotes the formation of insulin-producing cells from human induced pluripotent stem cells by targeting smad7 and TGIF2.
Cell death & disease
Li N,Jiang D,He Q,He F,Li Y,Deng C,Li F
Mon Jun 15 00:00:00 EDT 2020
iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome.
Stem cell reports
Atchison L,Abutaleb NO,Snyder-Mounts E,Gete Y,Ladha A,Ribar T,Cao K,Truskey GA
Tue Feb 11 00:00:00 EST 2020
Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC-Derived Embryonic Stage Mesodermal Precursor Cells.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Ullah I,Busch JF,Rabien A,Ergün B,Stamm C,Knosalla C,Hippenstiel S,Reinke P,Kurtz A
Sun Mar 01 00:00:00 EST 2020
The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.
The EMBO journal
Sainz de Aja J,Menchero S,Rollan I,Barral A,Tiana M,Jawaid W,Cossio I,Alvarez A,Carreño-Tarragona G,Badia-Careaga C,Nichols J,Göttgens B,Isern J,Manzanares M
Mon Apr 01 00:00:00 EDT 2019
Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells.
Journal of immunology (Baltimore, Md. : 1950)
Stephenson S,Care MA,Fan I,Zougman A,Westhead DR,Doody GM,Tooze RM
Fri Feb 15 00:00:00 EST 2019
Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells.
Scientific reports
Pettinato G,Lehoux S,Ramanathan R,Salem MM,He LX,Muse O,Flaumenhaft R,Thompson MT,Rouse EA,Cummings RD,Wen X,Fisher RA
Thu Jun 20 00:00:00 EDT 2019
In vitro metabolic zonation through oxygen gradient on a chip.
Scientific reports
Tonon F,Giobbe GG,Zambon A,Luni C,Gagliano O,Floreani A,Grassi G,Elvassore N
Thu Sep 19 00:00:00 EDT 2019
Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.
Theranostics
Li J,Yang KY,Tam RCY,Chan VW,Lan HY,Hori S,Zhou B,Lui KO
120-14E was used in Cell Culture to investigate the role of Treg in neonatal heart regeneration in mice.
Fri Aug 14 00:00:00 EDT 2020
Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects.
Cell reports
Ooi J,Langley SR,Xu X,Utami KH,Sim B,Huang Y,Harmston NP,Tay YL,Ziaei A,Zeng R,Low D,Aminkeng F,Sobota RM,Ginhoux F,Petretto E,Pouladi MA
120-14E was used in In vitro experiments to use genome editing to generate an allelic panel of isogenic Huntington disease (HD) (IsoHD) human embryonic stem cell (hESC) lines carrying varying CAG repeat lengths in the first exon of HTT.
Tue Feb 26 00:00:00 EST 2019
The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.
The Journal of biological chemistry
Wang X,Wang X,Zhang S,Sun H,Li S,Ding H,You Y,Zhang X,Ye SD
Fri Apr 12 00:00:00 EDT 2019
The transcription factor TFCP2L1 induces expression of distinct target genes and promotes self-renewal of mouse and human embryonic stem cells.
The Journal of biological chemistry
Wang X,Wang X,Zhang S,Sun H,Li S,Ding H,You Y,Zhang X,Ye SD
Fri Apr 12 00:00:00 EDT 2019
The Differences in the Characteristics of Insulin-producing Cells Using Human Adipose-tissue Derived Mesenchymal Stem Cells from Subcutaneous and Visceral Tissues.
Scientific reports
Wada Y,Ikemoto T,Morine Y,Imura S,Saito Y,Yamada S,Shimada M
Fri Sep 13 00:00:00 EDT 2019
Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation.
iScience
Wang Y,Tatham MH,Schmidt-Heck W,Swann C,Singh-Dolt K,Meseguer-Ripolles J,Lucendo-Villarin B,Kunath T,Rudd TR,Smith AJH,Hengstler JG,Godoy P,Hay RT,Hay DC
120-14E was used in Cell Culture to demonstrate that nuclear HNF4α is essential for hepatic progenitor specification, and the introduction of point mutations in HNF4α's Small Ubiquitin-like Modifier consensus motif leads to disrupted hepatocyte differentiation.
Fri Jun 28 00:00:00 EDT 2019
Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.
Nature methods
Di Stefano B,Ueda M,Sabri S,Brumbaugh J,Huebner AJ,Sahakyan A,Clement K,Clowers KJ,Erickson AR,Shioda K,Gygi SP,Gu H,Shioda T,Meissner A,Takashima Y,Plath K,Hochedlinger K
Sat Sep 01 00:00:00 EDT 2018
Long Noncoding RNA RP11-380D23.2 Drives Distal-Proximal Patterning of the Lung by Regulating PITX2 Expression.
Stem cells (Dayton, Ohio)
Banerjee P,Surendran H,Bharti K,Morishita K,Varshney A,Pal R
Thu Feb 01 00:00:00 EST 2018
Barrier Properties and Transcriptome Expression in Human iPSC-Derived Models of the Blood-Brain Barrier.
Stem cells (Dayton, Ohio)
Delsing L,Dönnes P,Sánchez J,Clausen M,Voulgaris D,Falk A,Herland A,Brolén G,Zetterberg H,Hicks R,Synnergren J
Sat Dec 01 00:00:00 EST 2018
Survival of Mice with Gastrointestinal Acute Radiation Syndrome through Control of Bacterial Translocation.
Journal of immunology (Baltimore, Md. : 1950)
Suzuki F,Loucas BD,Ito I,Asai A,Suzuki S,Kobayashi M
Sun Jul 01 00:00:00 EDT 2018
NF-κB/MAPK activation underlies ACVR1-mediated inflammation in human heterotopic ossification.
JCI insight
Barruet E,Morales BM,Cain CJ,Ton AN,Wentworth KL,Chan TV,Moody TA,Haks MC,Ottenhoff TH,Hellman J,Nakamura MC,Hsiao EC
120-14E was used in In vitro experiments to examine the potential link between bone morphogenetic proteins and inflammation in patients with fibrodysplasia ossificans progressiva.
Thu Nov 15 00:00:00 EST 2018
NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells.
Nature communications
Uenishi GI,Jung HS,Kumar A,Park MA,Hadland BK,McLeod E,Raymond M,Moskvin O,Zimmerman CE,Theisen DJ,Swanson S,J Tamplin O,Zon LI,Thomson JA,Bernstein ID,Slukvin II
Tue May 08 00:00:00 EDT 2018
Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.
PloS one
Sambathkumar R,Akkerman R,Dastidar S,Roelandt P,Kumar M,Bajaj M,Mestre Rosa AR,Helsen N,Vanslembrouck V,Kalo E,Khurana S,Laureys J,Gysemans C,Faas MM,de Vos P,Verfaillie CM
120-14E was used in Cell Culture to investigate 14 transcription factors in multipotent adult progenitor cell reprogramming for hepatocyte and endocrine pacreatic-like cell culture.
Tue Jul 31 00:00:00 EDT 2018
Stroma-derived IL-6, G-CSF and Activin-A mediated dedifferentiation of lung carcinoma cells into cancer stem cells.
Scientific reports
Rodrigues CFD,Serrano E,Patrício MI,Val MM,Albuquerque P,Fonseca J,Gomes CMF,Abrunhosa AJ,Paiva A,Carvalho L,Botelho MF,Almeida L,Carreira IM,Alpoim MC
Wed Aug 01 00:00:00 EDT 2018
iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors.
Cell death & disease
Melguizo-Sanchis D,Xu Y,Taheem D,Yu M,Tilgner K,Barta T,Gassner K,Anyfantis G,Wan T,Elango R,Alharthi S,El-Harouni AA,Przyborski S,Adam S,Saretzki G,Samarasinghe S,Armstrong L,Lako M
Fri Jan 26 00:00:00 EST 2018
Differentiation of primate primordial germ cell-like cells following transplantation into the adult gonadal niche.
Nature communications
Sosa E,Chen D,Rojas EJ,Hennebold JD,Peters KA,Wu Z,Lam TN,Mitchell JM,Sukhwani M,Tailor RC,Meistrich ML,Orwig KE,Shetty G,Clark AT
Mon Dec 17 00:00:00 EST 2018
High fidelity CRISPR/Cas9 increases precise monoallelic and biallelic editing events in primordial germ cells.
Scientific reports
Idoko-Akoh A,Taylor L,Sang HM,McGrew MJ
Thu Oct 11 00:00:00 EDT 2018
MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells.
Nature communications
Bahat A,Goldman A,Zaltsman Y,Khan DH,Halperin C,Amzallag E,Krupalnik V,Mullokandov M,Silberman A,Erez A,Schimmer AD,Hanna JH,Gross A
Mon Dec 03 00:00:00 EST 2018
Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models.
Stem cell reports
Lundin A,Delsing L,Clausen M,Ricchiuto P,Sanchez J,Sabirsh A,Ding M,Synnergren J,Zetterberg H,Brolén G,Hicks R,Herland A,Falk A
Tue Mar 13 00:00:00 EDT 2018
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development.
Cell stem cell
Shi ZD,Lee K,Yang D,Amin S,Verma N,Li QV,Zhu Z,Soh CL,Kumar R,Evans T,Chen S,Huangfu D
120-14E was used in Cell Culture to investigate the association between human GATA6 haploinsufficiency and a wide range of clinical phenotypes that include neonatal and adult-onset diabetes using CRISPR (clustered regularly interspaced short palindromic repeat)/Cas9-mediated genome editing coupled with human pluripotent stem cell (hPSC) directed differentiation.
Thu May 04 00:00:00 EDT 2017
Jun-Mediated Changes in Cell Adhesion Contribute to Mouse Embryonic Stem Cell Exit from Ground State Pluripotency.
Stem cells (Dayton, Ohio)
Veluscek G,Li Y,Yang SH,Sharrocks AD
Sun May 01 00:00:00 EDT 2016
GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells.
Stem cell reports
D'Souza SS,Maufort J,Kumar A,Zhang J,Smuga-Otto K,Thomson JA,Slukvin II
Tue Feb 09 00:00:00 EST 2016
Human induced pluripotent stem cell-derived hepatic cell lines as a new model for host interaction with hepatitis B virus.
Scientific reports
Kaneko S,Kakinuma S,Asahina Y,Kamiya A,Miyoshi M,Tsunoda T,Nitta S,Asano Y,Nagata H,Otani S,Kawai-Kitahata F,Murakawa M,Itsui Y,Nakagawa M,Azuma S,Nakauchi H,Nishitsuji H,Ujino S,Shimotohno K,Iwamoto M,Watashi K,Wakita T,Watanabe M
Fri Jul 08 00:00:00 EDT 2016
Redifferentiation of expanded human islet β cells by inhibition of ARX.
Scientific reports
Friedman-Mazursky O,Elkon R,Efrat S
Tue Feb 09 00:00:00 EST 2016
Inappropriate cadherin switching in the mouse epiblast compromises proper signaling between the epiblast and the extraembryonic ectoderm during gastrulation.
Scientific reports
Basilicata MF,Frank M,Solter D,Brabletz T,Stemmler MP
Tue May 24 00:00:00 EDT 2016
Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.
Scientific reports
Kim HM,Kim JW,Choi Y,Chun HS,Im I,Han YM,Song CW,Yoon S,Park HJ
Mon Feb 22 00:00:00 EST 2016
The Epstein-Barr virus encoded LMP1 oncoprotein modulates cell adhesion via regulation of activin A/TGFβ and β1 integrin signalling.
Scientific reports
Morris MA,Dawson CW,Laverick L,Davis AM,Dudman JP,Raveenthiraraj S,Ahmad Z,Yap LF,Young LS
Tue Jan 19 00:00:00 EST 2016
Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors.
Current protocols in stem cell biology
Rothová M,Hölzenspies JJ,Livigni A,Villegas SN,Brickman JM
120-14E was used in Cell Culture to describe a method for the differentiation of mouse embryonic stem cells (mESCs) to definitive endoderm with pronounced anterior character.
Wed Feb 03 00:00:00 EST 2016
Induction of Germ Cell-like Cells from Porcine Induced Pluripotent Stem Cells.
Scientific reports
Wang H,Xiang J,Zhang W,Li J,Wei Q,Zhong L,Ouyang H,Han J
Mon Jun 06 00:00:00 EDT 2016
H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro.
Stem cell reports
Vanhove J,Pistoni M,Welters M,Eggermont K,Vanslembrouck V,Helsen N,Boon R,Najimi M,Sokal E,Collas P,Voncken JW,Verfaillie CM
Tue Aug 09 00:00:00 EDT 2016
Establishment of feeder-free culture system for human induced pluripotent stem cell on DAS nanocrystalline graphene.
Scientific reports
Lee H,Nam D,Choi JK,Araúzo-Bravo MJ,Kwon SY,Zaehres H,Lee T,Park CY,Kang HW,Schöler HR,Kim JB
Fri Feb 05 00:00:00 EST 2016
Ctbp2 Modulates NuRD-Mediated Deacetylation of H3K27 and Facilitates PRC2-Mediated H3K27me3 in Active Embryonic Stem Cell Genes During Exit from Pluripotency.
Stem cells (Dayton, Ohio)
Kim TW,Kang BH,Jang H,Kwak S,Shin J,Kim H,Lee SE,Lee SM,Lee JH,Kim JH,Kim SY,Cho EJ,Kim JH,Park KS,Che JH,Han DW,Kang MJ,Yi EC,Youn HD
Sat Aug 01 00:00:00 EDT 2015
Multipotent caudal neural progenitors derived from human pluripotent stem cells that give rise to lineages of the central and peripheral nervous system.
Stem cells (Dayton, Ohio)
Denham M,Hasegawa K,Menheniott T,Rollo B,Zhang D,Hough S,Alshawaf A,Febbraro F,Ighaniyan S,Leung J,Elliott DA,Newgreen DF,Pera MF,Dottori M
Mon Jun 01 00:00:00 EDT 2015
Mitochondrial Respiratory Defect Causes Dysfunctional Lactate Turnover via AMP-activated Protein Kinase Activation in Human-induced Pluripotent Stem Cell-derived Hepatocytes.
The Journal of biological chemistry
Im I,Jang MJ,Park SJ,Lee SH,Choi JH,Yoo HW,Kim S,Han YM
Fri Dec 04 00:00:00 EST 2015
Renal progenitors derived from human iPSCs engraft and restore function in a mouse model of acute kidney injury.
Scientific reports
Imberti B,Tomasoni S,Ciampi O,Pezzotta A,Derosas M,Xinaris C,Rizzo P,Papadimou E,Novelli R,Benigni A,Remuzzi G,Morigi M
Fri Mar 06 00:00:00 EST 2015
PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation.
Nature communications
Yu JS,Ramasamy TS,Murphy N,Holt MK,Czapiewski R,Wei SK,Cui W
Fri May 22 00:00:00 EDT 2015
Induced pluripotent stem cells as a model for diabetes investigation.
Scientific reports
Stepniewski J,Kachamakova-Trojanowska N,Ogrocki D,Szopa M,Matlok M,Beilharz M,Dyduch G,Malecki MT,Jozkowicz A,Dulak J
Thu Feb 26 00:00:00 EST 2015
Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes.
Stem cell reports
Cameron K,Tan R,Schmidt-Heck W,Campos G,Lyall MJ,Wang Y,Lucendo-Villarin B,Szkolnicka D,Bates N,Kimber SJ,Hengstler JG,Godoy P,Forbes SJ,Hay DC
Tue Dec 08 00:00:00 EST 2015
Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
Nature biotechnology
Sherwood RI,Hashimoto T,O'Donnell CW,Lewis S,Barkal AA,van Hoff JP,Karun V,Jaakkola T,Gifford DK
Sat Feb 01 00:00:00 EST 2014
Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs.
Proceedings of the National Academy of Sciences of the United States of America
Park CY,Kim J,Kweon J,Son JS,Lee JS,Yoo JE,Cho SR,Kim JH,Kim JS,Kim DW
Tue Jun 24 00:00:00 EDT 2014
BMP4 promotes EMT and mesodermal commitment in human embryonic stem cells via SLUG and MSX2.
Stem cells (Dayton, Ohio)
Richter A,Valdimarsdottir L,Hrafnkelsdottir HE,Runarsson JF,Omarsdottir AR,Ward-van Oostwaard D,Mummery C,Valdimarsdottir G
Sat Mar 01 00:00:00 EST 2014
Formation of well-defined embryoid bodies from dissociated human induced pluripotent stem cells using microfabricated cell-repellent microwell arrays.
Scientific reports
Pettinato G,Wen X,Zhang N
Wed Dec 10 00:00:00 EST 2014
Deriving functional hepatocytes from pluripotent stem cells.
Current protocols in stem cell biology
Szkolnicka D,Farnworth SL,Lucendo-Villarin B,Hay DC
120-14E was used in Cell Culture to develop robust hepatocyte differentiation methodologies for use with pluripotent stem cells.
Fri Aug 01 00:00:00 EDT 2014
Deterministic direct reprogramming of somatic cells to pluripotency.
Nature
Rais Y,Zviran A,Geula S,Gafni O,Chomsky E,Viukov S,Mansour AA,Caspi I,Krupalnik V,Zerbib M,Maza I,Mor N,Baran D,Weinberger L,Jaitin DA,Lara-Astiaso D,Blecher-Gonen R,Shipony Z,Mukamel Z,Hagai T,Gilad S,Amann-Zalcenstein D,Tanay A,Amit I,Novershtern N,Hanna JH
Thu Oct 03 00:00:00 EDT 2013
Role of SOX17 in hematopoietic development from human embryonic stem cells.
Blood
Nakajima-Takagi Y,Osawa M,Oshima M,Takagi H,Miyagi S,Endoh M,Endo TA,Takayama N,Eto K,Toyoda T,Koseki H,Nakauchi H,Iwama A
Thu Jan 17 00:00:00 EST 2013
The H3K27 demethylase Utx regulates somatic and germ cell epigenetic reprogramming.
Nature
Mansour AA,Gafni O,Weinberger L,Zviran A,Ayyash M,Rais Y,Krupalnik V,Zerbib M,Amann-Zalcenstein D,Maza I,Geula S,Viukov S,Holtzman L,Pribluda A,Canaani E,Horn-Saban S,Amit I,Novershtern N,Hanna JH
Thu Aug 16 00:00:00 EDT 2012
Generation of multipotent lung and airway progenitors from mouse ESCs and patient-specific cystic fibrosis iPSCs.
Cell stem cell
Mou H,Zhao R,Sherwood R,Ahfeldt T,Lapey A,Wain J,Sicilian L,Izvolsky K,Musunuru K,Cowan C,Rajagopal J
Fri Apr 06 00:00:00 EDT 2012
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.
Proceedings of the National Academy of Sciences of the United States of America
Kajiwara M,Aoi T,Okita K,Takahashi R,Inoue H,Takayama N,Endo H,Eto K,Toguchida J,Uemoto S,Yamanaka S
Tue Jul 31 00:00:00 EDT 2012
Attenuation of extrinsic signaling reveals the importance of matrix remodeling on maintenance of embryonic stem cell self-renewal.
Proceedings of the National Academy of Sciences of the United States of America
Przybyla LM,Voldman J
Tue Jan 17 00:00:00 EST 2012
Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells.
Stem cells (Dayton, Ohio)
Mellough CB,Sernagor E,Moreno-Gimeno I,Steel DH,Lako M
Sun Apr 01 00:00:00 EDT 2012
The prolyl hydroxylase PHD3 identifies proinflammatory macrophages and its expression is regulated by activin A.
Journal of immunology (Baltimore, Md. : 1950)
Escribese MM,Sierra-Filardi E,Nieto C,Samaniego R,Sánchez-Torres C,Matsuyama T,Calderon-Gómez E,Vega MA,Salas A,Sánchez-Mateos P,Corbí AL
Wed Aug 15 00:00:00 EDT 2012
Redifferentiation of expanded human pancreatic β-cell-derived cells by inhibition of the NOTCH pathway.
The Journal of biological chemistry
Bar Y,Russ HA,Sintov E,Anker-Kitai L,Knoller S,Efrat S
Fri May 18 00:00:00 EDT 2012
Dedifferentiation of foetal CNS stem cells to mesendoderm-like cells through an EMT process.
PloS one
Ber S,Lee C,Voiculescu O,Surani MA
Mon Jun 04 00:00:00 EDT 2012
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency.
Aging
Ohmine S,Squillace KA,Hartjes KA,Deeds MC,Armstrong AS,Thatava T,Sakuma T,Terzic A,Kudva Y,Ikeda Y
Sun Jan 01 00:00:00 EST 2012
Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc.
International journal of molecular sciences
Chang HM,Liao YW,Chiang CH,Chen YJ,Lai YH,Chang YL,Chen HL,Jeng SY,Hsieh JH,Peng CH,Li HY,Chien Y,Chen SY,Chen LK,Huo TI
Mon Aug 31 00:00:00 EDT 2015
Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells.
PloS one
Rodríguez-Martínez G,Molina-Hernández A,Velasco I
Tue Jan 29 00:00:00 EST 2013
PTK7 marks the first human developmental EMT in vitro.
PloS one
Chan DN,Azghadi SF,Feng J,Lowry WE
Mon Jun 24 00:00:00 EDT 2013
Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells.
Scientific reports
Umeda K,Zhao J,Simmons P,Stanley E,Elefanty A,Nakayama N
Mon Feb 25 00:00:00 EST 2013
TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages.
PloS one
Bourlier V,Sengenès C,Zakaroff-Girard A,Decaunes P,Wdziekonski B,Galitzky J,Villageois P,Esteve D,Chiotasso P,Dani C,Bouloumié A
Mon Jun 18 00:00:00 EDT 2012
Reconstitution of the mouse germ cell specification pathway in culture by pluripotent stem cells.
Cell
Hayashi K,Ohta H,Kurimoto K,Aramaki S,Saitou M
Fri Aug 19 00:00:00 EDT 2011
A poised chromatin platform for TGF-β access to master regulators.
Cell
Xi Q,Wang Z,Zaromytidou AI,Zhang XH,Chow-Tsang LF,Liu JX,Kim H,Barlas A,Manova-Todorova K,Kaartinen V,Studer L,Mark W,Patel DJ,Massagué J
Fri Dec 23 00:00:00 EST 2011
Hepatic differentiation of amniotic epithelial cells.
Hepatology (Baltimore, Md.)
Marongiu F,Gramignoli R,Dorko K,Miki T,Ranade AR,Paola Serra M,Doratiotto S,Sini M,Sharma S,Mitamura K,Sellaro TL,Tahan V,Skvorak KJ,Ellis EC,Badylak SF,Davila JC,Hines R,Laconi E,Strom SC
Sun May 01 00:00:00 EDT 2011
Histone variant macroH2A confers resistance to nuclear reprogramming.
The EMBO journal
Pasque V,Gillich A,Garrett N,Gurdon JB
Fri May 06 00:00:00 EDT 2011
Inducible cassette exchange: a rapid and efficient system enabling conditional gene expression in embryonic stem and primary cells.
Stem cells (Dayton, Ohio)
Iacovino M,Bosnakovski D,Fey H,Rux D,Bajwa G,Mahen E,Mitanoska A,Xu Z,Kyba M
Sat Oct 01 00:00:00 EDT 2011
Changes in glycosphingolipid composition during differentiation of human embryonic stem cells to ectodermal or endodermal lineages.
Stem cells (Dayton, Ohio)
Liang YJ,Yang BC,Chen JM,Lin YH,Huang CL,Cheng YY,Hsu CY,Khoo KH,Shen CN,Yu J
Thu Dec 01 00:00:00 EST 2011
Efficient derivation of human neuronal progenitors and neurons from pluripotent human embryonic stem cells with small molecule induction.
Journal of visualized experiments : JoVE
Parsons XH,Teng YD,Parsons JF,Snyder EY,Smotrich DB,Moore DA
Fri Oct 28 00:00:00 EDT 2011
Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro.
PloS one
Russ HA,Sintov E,Anker-Kitai L,Friedman O,Lenz A,Toren G,Farhy C,Pasmanik-Chor M,Oron-Karni V,Ravassard P,Efrat S
Mon Mar 05 00:00:00 EST 2012
Efficient generation of hepatocyte-like cells from human induced pluripotent stem cells.
Cell research
Song Z,Cai J,Liu Y,Zhao D,Yong J,Duo S,Song X,Guo Y,Zhao Y,Qin H,Yin X,Wu C,Che J,Lu S,Ding M,Deng H
Sun Nov 01 00:00:00 EDT 2009
