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Product Details
PEP-0996
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Class
Synthetic
Type
Peptide
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
purified
Storage buffer
PBS, pH 7.2, with 0.1% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Dry ice
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human NAT11.
PEP-0996 can be used as a blocking peptide with polyclonal antibody PA5-20882.
Target Information
N-terminal acetylation is one of the most common protein modifications in eukaryotes, occurring on approximately 57% and 84% on yeast and human proteins respectively. There are several N-terminal acetylating enzyme complexes (NatA - NatE). Unlike the other complexes, NatD is composed of a single protein, NAT11, and has recently been described to acetylate the Serine N-termini of histones H2A and H4 in yeast. The role these modifications play is unknown; yeast that do not express NAT11 grow at normal rates and have no observable phenotypes. The role of the human homolog is likewise unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog; N-acetyltransferase 11; N-acetyltransferase 11 (GCN5-related, putative); N-alpha acetyl transferase 40; N-alpha-acetyltransferase 40; N-alpha-acetyltransferase 40, NatD catalytic subunit; N-alpha-acetyltransferase D; NatD; natD catalytic subunit; Protein acetyltransferase 1
Gene Aliases: NAA40; NAT11; PATT1
UniProt ID: (Human) Q86UY6
Entrez Gene ID: (Human) 79829
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