Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (46%), Rat (46%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54216. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any one of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also designated NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that is believed to not be involved in catalysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CI-9kD; complex I 10kDa subunit; complex I, mitochondrial respiratory chain, 10-kD subunit; Complex I-9kD; mitochondrial NADH oxidoreductase-like protein; NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa; NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial; NADH-ubiquinone oxidoreductase 9 kD subunit; NADH-ubiquinone oxidoreductase 9 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 3, 10kD; Renal carcinoma antigen NY-REN-4
Gene Aliases: CI-10k; CI-9KD; NDUFV3
UniProt ID: (Human) P56181
Entrez Gene ID: (Human) 4731
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