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Product Details
RP-98309
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
VLKEQLERKRKEAYEREKKVWEEHLVAKGVKSSDVSPPLGQHETGGSPSKQQMRSVISVTSALKEVGVDSSLTDTRETSEEMQKTNNAISSKR
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (81%), Rat (81%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59166. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
NEK1 is a serine/threonine protein kinase, related to the NIMA cell cycle regulator, and is highly expressed in meiotic germ cells. The kinase may function early in the DNA damage response pathway. NEK1 may also participate in polycystic kidney disease and neural cell development. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686D06121; DKFZp686K12169; MGC138800; Never in mitosis A-related kinase 1; NIMA (never in mitosis gene a)-related kinase 1; NIMA-related kinase 1; NimA-related protein kinase 1; NY REN55; protein-serine/threonine kinase; Renal carcinoma antigen NY-REN-55; Serine/threonine-protein kinase Nek1
Gene Aliases: KIAA1901; NEK1; NY-REN-55; SRPS2; SRPS2A; SRTD6
UniProt ID: (Human) Q96PY6
Entrez Gene ID: (Human) 4750
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