Product References
The cytokine receptor CRLF3 is a human neuroprotective EV-3 (Epo) receptor.
Frontiers in molecular neuroscience
Knorr DY,Rodriguez Polo I,Pies HS,Schwedhelm-Domeyer N,Pauls S,Behr R,Heinrich R
AF-450-03 was used in Cell Culture to show that the human CRLF3 mediates neuroprotection upon activation with the natural Epo splice variant EV-3.
Sun May 14 00:00:00 EDT 2023
Spatially controlled construction of assembloids using bioprinting.
Nature communications
Roth JG,Brunel LG,Huang MS,Liu Y,Cai B,Sinha S,Yang F,Pașca SP,Shin S,Heilshorn SC
AF-450-03 was used in Cell Culture to demonstrate the potential for the SPOT platform to construct assembloids which recapitulate key developmental processes and disease etiologies.
Wed Jul 19 00:00:00 EDT 2023
Expression of Lineage Transcription Factors Identifies Differences in Transition States of Induced Human Oligodendrocyte Differentiation.
Cells
Raabe FJ,Stephan M,Waldeck JB,Huber V,Demetriou D,Kannaiyan N,Galinski S,Glaser LV,Wehr MC,Ziller MJ,Schmitt A,Falkai P,Rossner MJ
AF-450-03 was used in In vitro experiments to highlight that TFs for generating iOPCs or iOLs should be chosen depending on the intended application or research question, and that SON might be beneficial to study more mature iOLs while S might be better suited to investigate iOPC biology.
Tue Jan 11 00:00:00 EST 2022
Doublecortin-like Kinase 1 Regulates α-Synuclein Levels and Toxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience
Vázquez-Vélez GE,Gonzales KA,Revelli JP,Adamski CJ,Alavi Naini F,Bajić A,Craigen E,Richman R,Heman-Ackah SM,Wood MJA,Rousseaux MWC,Zoghbi HY
AF-450-03 was used in Cell Culture to provide evidence for a novel function for DCLK1 in the mature brain, and for its potential as a new therapeutic target for synucleinopathies.
Wed Jan 08 00:00:00 EST 2020
Inhibition of Apoptosis Reduces Diploidization of Haploid Mouse Embryonic Stem Cells during Differentiation.
Stem cell reports
Zhang W,Tian Y,Gao Q,Li X,Li Y,Zhang J,Yao C,Wang Y,Wang H,Zhao Y,Zhang Q,Li L,Yu Y,Fan Y,Shuai L
Tue Jul 14 00:00:00 EDT 2020
Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury.
Nature communications
Floriddia EM,Lourenço T,Zhang S,van Bruggen D,Hilscher MM,Kukanja P,Gonçalves Dos Santos JP,Altınkök M,Yokota C,Llorens-Bobadilla E,Mulinyawe SB,Grãos M,Sun LO,Frisén J,Nilsson M,Castelo-Branco G
Tue Nov 17 00:00:00 EST 2020
Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs.
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Feng L,Chao J,Tian E,Li L,Ye P,Zhang M,Chen X,Cui Q,Sun G,Zhou T,Felix G,Qin Y,Li W,Meza ED,Klein J,Ghoda L,Hu W,Luo Y,Dang W,Hsu D,Gold J,Goldman SA,Matalon R,Shi Y
Tue Dec 01 00:00:00 EST 2020
mTOR and autophagy pathways are dysregulated in murine and human models of Schaaf-Yang syndrome.
Scientific reports
Crutcher E,Pal R,Naini F,Zhang P,Laugsch M,Kim J,Bajic A,Schaaf CP
Mon Nov 04 00:00:00 EST 2019
Mitochondrial deficits in human iPSC-derived neurons from patients with 22q11.2 deletion syndrome and schizophrenia.
Translational psychiatry
Li J,Ryan SK,Deboer E,Cook K,Fitzgerald S,Lachman HM,Wallace DC,Goldberg EM,Anderson SA
Mon Nov 18 00:00:00 EST 2019
ATXN1-CIC Complex Is the Primary Driver of Cerebellar Pathology in Spinocerebellar Ataxia Type 1 through a Gain-of-Function Mechanism.
Neuron
Rousseaux MWC,Tschumperlin T,Lu HC,Lackey EP,Bondar VV,Wan YW,Tan Q,Adamski CJ,Friedrich J,Twaroski K,Chen W,Tolar J,Henzler C,Sharma A,Bajić A,Lin T,Duvick L,Liu Z,Sillitoe RV,Zoghbi HY,Orr HT
Wed Mar 21 00:00:00 EDT 2018
(Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation.
EMBO reports
Fiesel FC,Ando M,Hudec R,Hill AR,Castanedes-Casey M,Caulfield TR,Moussaud-Lamodière EL,Stankowski JN,Bauer PO,Lorenzo-Betancor O,Ferrer I,Arbelo JM,Siuda J,Chen L,Dawson VL,Dawson TM,Wszolek ZK,Ross OA,Dickson DW,Springer W
AF-450-03 was used in Cell Culture to suggest that pS65-Ub accumulates with stress, disease, or age, and highlight its significance and potential for future biomarker and/or therapeutic development.
Tue Sep 01 00:00:00 EDT 2015
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
Cell
Xue Y,Ouyang K,Huang J,Zhou Y,Ouyang H,Li H,Wang G,Wu Q,Wei C,Bi Y,Jiang L,Cai Z,Sun H,Zhang K,Zhang Y,Chen J,Fu XD
Thu Jan 17 00:00:00 EST 2013
Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits.
Cell
Xue Y,Ouyang K,Huang J,Zhou Y,Ouyang H,Li H,Wang G,Wu Q,Wei C,Bi Y,Jiang L,Cai Z,Sun H,Zhang K,Zhang Y,Chen J,Fu XD
Thu Jan 17 00:00:00 EST 2013
Long-distance growth and connectivity of neural stem cells after severe spinal cord injury.
Cell
Lu P,Wang Y,Graham L,McHale K,Gao M,Wu D,Brock J,Blesch A,Rosenzweig ES,Havton LA,Zheng B,Conner JM,Marsala M,Tuszynski MH
Fri Sep 14 00:00:00 EDT 2012
Coseeded Schwann cells myelinate neurites from differentiated neural stem cells in neurotrophin-3-loaded PLGA carriers.
International journal of nanomedicine
Xiong Y,Zhu JX,Fang ZY,Zeng CG,Zhang C,Qi GL,Li MH,Zhang W,Quan DP,Wan J
Wed Sep 26 00:00:00 EDT 2012
Coseeded Schwann cells myelinate neurites from differentiated neural stem cells in neurotrophin-3-loaded PLGA carriers.
International journal of nanomedicine
Xiong Y,Zhu JX,Fang ZY,Zeng CG,Zhang C,Qi GL,Li MH,Zhang W,Quan DP,Wan J
Wed Sep 26 00:00:00 EDT 2012
miR-200c targets a NF-κB up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer.
PloS one
Howe EN,Cochrane DR,Cittelly DM,Richer JK
Thu May 30 00:00:00 EDT 2013
Oligodendrocyte differentiation from adult multipotent stem cells is modulated by glutamate.
Cell death & disease
Cavaliere F,Urra O,Alberdi E,Matute C
Thu Feb 02 00:00:00 EST 2012
3D multicolor super-resolution imaging offers improved accuracy in neuron tracing.
PloS one
Lakadamyali M,Babcock H,Bates M,Zhuang X,Lichtman J
Mon Jun 04 00:00:00 EDT 2012
Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons.
Cell
Qiang L,Fujita R,Yamashita T,Angulo S,Rhinn H,Rhee D,Doege C,Chau L,Aubry L,Vanti WB,Moreno H,Abeliovich A
Fri Aug 05 00:00:00 EDT 2011
Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Papadeas ST,Kraig SE,O'Banion C,Lepore AC,Maragakis NJ
Tue Oct 25 00:00:00 EDT 2011
Biophysical characteristics reveal neural stem cell differentiation potential.
PloS one
Labeed FH,Lu J,Mulhall HJ,Marchenko SA,Hoettges KF,Estrada LC,Lee AP,Hughes MP,Flanagan LA
Thu Jan 26 00:00:00 EST 2012
