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Highest antigen sequence indentity to the following orthologs: Mouse (92%), Rat (92%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53729. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A6 protein tyrosine kinase; Protein A6; Protein tyrosine kinase 9; PTK9 protein tyrosine kinase 9; twinfilin actin-binding protein 1; twinfilin, actin-binding protein, homolog 1; Twinfilin-1
Gene Aliases: A6; PTK9; TWF1
UniProt ID: (Human) Q12792
Entrez Gene ID: (Human) 5756
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