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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84450. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DKFZP586K0919; DKFZp762A152; Sentrin-specific protease 3; sentrin/SUMO-specific protease 3; Sentrin/SUMO-specific protease SENP3; SUMO-1-specific protease 3
Gene Aliases: SENP3; SMT3IP1; SSP3; SUSP3; Ulp1
UniProt ID: (Human) Q9H4L4
Entrez Gene ID: (Human) 26168
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