Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-63622. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
This gene encodes a protein which contains an N-terminal sterile alpha motif (SAM) for protein-protein interactions, followed by an ATP/GTP-binding motif, a GTPase-activating protein (GAP) domain, and a C-terminal STAR-related lipid transfer (START) domain. It may be involved in regulation of cytoskeletal reorganization, cell proliferation, and cell motility, and acts as a tumor suppressor in hepatoma cells. The gene is located in a region of chromosome 13 that is associated with loss of heterozygosity in hepatocellular carcinomas. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 46H23.2; Deleted in liver cancer 2 protein; DLC-2; long intergenic non-protein coding RNA 464; Rho GTPase activating protein on chromosome 13q12; Rho GTPase-activating protein; STA13; StAR-related lipid transfer (START) domain containing 13; StAR-related lipid transfer domain containing 13; StAR-related lipid transfer protein 13; StARD13; START domain-containing protein 13
Gene Aliases: ARHGAP37; DLC2; GT650; LINC00464; STARD13
UniProt ID: (Human) Q9Y3M8
Entrez Gene ID: (Human) 90627
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