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Invitrogen
Human STEAP2 (aa 131-202) Control Fragment Recombinant Protein
Product Details
RP-90807
Applications
Tested Dilution
Publications
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
EYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPIDLGSLSSAREIE
Tag
His-ABP-tag
Class
Recombinant
Type
Protein
Purity
>80% by SDS-PAGE and Coomassie blue staining
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
purified
Storage buffer
PBS/1M urea, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (96%), Rat (96%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The six-transmembrane epithelial antigen of prostate 2 (STEAP2) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 3 and STEAP4), STEAP2 promotes both iron and copper reduction. STEAP2 expression in transfected cells also correlated with iron or copper uptake, suggesting that the STEAP family of proteins may function to stimulate iron and copper uptake. STEAP2 is widely expressed in many tissues in the plasma membrane, but is most highly expressed in prostate. At least three isoforms of STEAP2 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Metalloreductase STEAP2; prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up-regulated in metastatic prostate cancer; protein upregulated in metastatic prostate cancer; PUMPCn; six transmembrane epithelial antigen of prostate 2; six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane Protein of Prostate 1; STEAP family member 2, metalloreductase
Gene Aliases: IPCA1; PCANAP1; PUMPCn; STAMP1; STEAP2; STMP; UNQ6507/PRO23203
UniProt ID: (Human) Q8NFT2
Entrez Gene ID: (Human) 261729
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