Product References
Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming.
Journal of immunology (Baltimore, Md. : 1950)
Chen X,Liu Y,Dolin H,Liu J,Jiang Y,Pan ZK
Thu Apr 15 00:00:00 EDT 2021
Activation of the adipocyte CREB/CRTC pathway in obesity.
Communications biology
Yoon YS,Liu W,Van de Velde S,Matsumura S,Wiater E,Huang L,Montminy M
Fri Oct 22 00:00:00 EDT 2021
Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils.
Mucosal immunology
Fonseca KL,Maceiras AR,Matos R,Simoes-Costa L,Sousa J,Cá B,Barros L,Fernandes AI,Mereiter S,Reis R,Gomes J,Tapia G,Rodríguez-Martínez P,Martín-Céspedes M,Vashakidze S,Gogishvili S,Nikolaishvili K,Appelberg R,Gärtner F,Rodrigues PNS,Vilaplana C,Reis CA,Magalhães A,Saraiva M
Tue Sep 01 00:00:00 EDT 2020
Signaling and functional competency of neutrophils derived from bone-marrow cells expressing the ER-HOXB8 oncoprotein.
Journal of leukocyte biology
Saul S,Castelbou C,Fickentscher C,Demaurex N
Fri Nov 01 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer.
Cell reports
Di Mitri D,Mirenda M,Vasilevska J,Calcinotto A,Delaleu N,Revandkar A,Gil V,Boysen G,Losa M,Mosole S,Pasquini E,D'Antuono R,Masetti M,Zagato E,Chiorino G,Ostano P,Rinaldi A,Gnetti L,Graupera M,Martins Figueiredo Fonseca AR,Pereira Mestre R,Waugh D,Barry S,De Bono J,Alimonti A
250-15 was used in Cell Culture to identify tumor-associated macrophages as targets in prostate cancer and describe a therapeutic strategy based on CXCR2 blockade to harness anti-tumorigenic potential of macrophages against this disease.
Tue Aug 20 00:00:00 EDT 2019
IL-8 induces transdifferentiation of mature hepatocytes toward the cholangiocyte phenotype.
FEBS open bio
Sasaki T,Suzuki Y,Kakisaka K,Wang T,Ishida K,Suzuki A,Abe H,Sugai T,Takikawa Y
Sun Dec 01 00:00:00 EST 2019
Modulation of double-stranded RNA pattern recognition receptor signaling in ovarian cancer cells promotes inflammatory queues.
Oncotarget
Muccioli M,Nandigam H,Loftus T,Singh M,Venkatesh A,Wright J,Pate M,McCall K,Benencia F
250-15 was used in Enzyme-linked immunosorbent assay to investigate the potential of mouse and human ovarian cancer cells to produce inflammatory factors in response to pathogen recognition receptor signalling.
Fri Nov 30 00:00:00 EST 2018
Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation.
Nature communications
Taki M,Abiko K,Baba T,Hamanishi J,Yamaguchi K,Murakami R,Yamanoi K,Horikawa N,Hosoe Y,Nakamura E,Sugiyama A,Mandai M,Konishi I,Matsumura N
Fri Apr 27 00:00:00 EDT 2018
Genetic modification to induce CXCR2 overexpression in mesenchymal stem cells enhances treatment benefits in radiation-induced oral mucositis.
Cell death & disease
Shen Z,Wang J,Huang Q,Shi Y,Wei Z,Zhang X,Qiu Y,Zhang M,Wang Y,Qin W,Huang S,Huang Y,Liu X,Xia K,Zhang X,Lin Z
Wed Feb 14 00:00:00 EST 2018
CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein-Coupled Receptor CXCR2.
Journal of immunology (Baltimore, Md. : 1950)
Boro M,Balaji KN
Fri Sep 01 00:00:00 EDT 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Scientific reports
Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW
Wed Nov 22 00:00:00 EST 2017
Type 2 Interleukin-4 Receptor Signaling in Neutrophils Antagonizes Their Expansion and Migration during Infection and Inflammation.
Immunity
Woytschak J,Keller N,Krieg C,Impellizzieri D,Thompson RW,Wynn TA,Zinkernagel AS,Boyman O
Tue Jul 19 00:00:00 EDT 2016
Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses.
Scientific reports
Boro M,Singh V,Balaji KN
Thu Nov 24 00:00:00 EST 2016
Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses.
Scientific reports
Boro M,Singh V,Balaji KN
Thu Nov 24 00:00:00 EST 2016
Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo.
Nature communications
Németh T,Futosi K,Sitaru C,Ruland J,Mócsai A
Fri Apr 01 00:00:00 EDT 2016
The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8.
Journal of immunology (Baltimore, Md. : 1950)
Severa M,Islam SA,Waggoner SN,Jiang Z,Kim ND,Ryan G,Kurt-Jones E,Charo I,Caffrey DR,Boyartchuk VL,Luster AD,Fitzgerald KA
Sat Mar 01 00:00:00 EST 2014
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
The Journal of cell biology
Liou GY,Döppler H,Necela B,Krishna M,Crawford HC,Raimondo M,Storz P
Mon Aug 05 00:00:00 EDT 2013
Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells.
PloS one
Fossati-Jimack L,Ling GS,Cortini A,Szajna M,Malik TH,McDonald JU,Pickering MC,Cook HT,Taylor PR,Botto M
Fri Sep 27 00:00:00 EDT 2013
Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells.
PloS one
Fossati-Jimack L,Ling GS,Cortini A,Szajna M,Malik TH,McDonald JU,Pickering MC,Cook HT,Taylor PR,Botto M
Fri Sep 27 00:00:00 EDT 2013
Phagocytosis is the main CR3-mediated function affected by the lupus-associated variant of CD11b in human myeloid cells.
PloS one
Fossati-Jimack L,Ling GS,Cortini A,Szajna M,Malik TH,McDonald JU,Pickering MC,Cook HT,Taylor PR,Botto M
Fri Sep 27 00:00:00 EDT 2013
Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice.
Blood
Axelsson J,Xu D,Kang BN,Nussbacher JK,Handel TM,Ley K,Sriramarao P,Esko JD
Thu Aug 23 00:00:00 EDT 2012
Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment.
Journal of cell science
Singh RK,Liao W,Tracey-White D,Recchi C,Tolmachova T,Rankin SM,Hume AN,Seabra MC
Sun Apr 01 00:00:00 EDT 2012
Rab27a-mediated protease release regulates neutrophil recruitment by allowing uropod detachment.
Journal of cell science
Singh RK,Liao W,Tracey-White D,Recchi C,Tolmachova T,Rankin SM,Hume AN,Seabra MC
Sun Apr 01 00:00:00 EDT 2012
Altered regulation of Toll-like receptor responses impairs antibacterial immunity in the allergic lung.
Mucosal immunology
Habibzay M,Saldana JI,Goulding J,Lloyd CM,Hussell T
250-15 was used in Cell Culture to show an imbalance in novel antibacterial pathways that culminates in a reduction in neutrophil recruitment to the airspaces and leads to bacterial invasion and dissemination.
Sat Sep 01 00:00:00 EDT 2012
Regulation of the estrous cycle by neutrophils via opioid peptides.
Journal of immunology (Baltimore, Md. : 1950)
Sasaki S,Tamaki Y,Nagata K,Kobayashi Y
Fri Jul 15 00:00:00 EDT 2011
TLT2 potentiates neutrophil antibacterial activity and chemotaxis in response to G protein-coupled receptor-mediated signaling.
Journal of immunology (Baltimore, Md. : 1950)
Halpert MM,Thomas KA,King RG,Justement LB
Thu Sep 01 00:00:00 EDT 2011
DNA damage-mediated induction of a chemoresistant niche.
Cell
Gilbert LA,Hemann MT
Fri Oct 29 00:00:00 EDT 2010
CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection.
Immunity
Mei J,Liu Y,Dai N,Favara M,Greene T,Jeyaseelan S,Poncz M,Lee JS,Worthen GS
Fri Jul 23 00:00:00 EDT 2010
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction.
Blood
Nguyen-Jackson H,Panopoulos AD,Zhang H,Li HS,Watowich SS
Thu Apr 22 00:00:00 EDT 2010
STAT3 controls the neutrophil migratory response to CXCR2 ligands by direct activation of G-CSF-induced CXCR2 expression and via modulation of CXCR2 signal transduction.
Blood
Nguyen-Jackson H,Panopoulos AD,Zhang H,Li HS,Watowich SS
Thu Apr 22 00:00:00 EDT 2010
Migration of engrafted neural stem cells is mediated by CXCL12 signaling through CXCR4 in a viral model of multiple sclerosis.
Proceedings of the National Academy of Sciences of the United States of America
Carbajal KS,Schaumburg C,Strieter R,Kane J,Lane TE
Tue Jun 15 00:00:00 EDT 2010
CXC chemokine ligand 2 induced by receptor activator of NF-kappa B ligand enhances osteoclastogenesis.
Journal of immunology (Baltimore, Md. : 1950)
Ha J,Choi HS,Lee Y,Kwon HJ,Song YW,Kim HH
Sat May 01 00:00:00 EDT 2010
Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs.
Journal of immunology (Baltimore, Md. : 1950)
Tanino Y,Coombe DR,Gill SE,Kett WC,Kajikawa O,Proudfoot AE,Wells TN,Parks WC,Wight TN,Martin TR,Frevert CW
Mon Mar 01 00:00:00 EST 2010
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.
Journal of immunology (Baltimore, Md. : 1950)
Kono H,Karmarkar D,Iwakura Y,Rock KL
Thu Apr 15 00:00:00 EDT 2010
Dyslipidemia induces opposing effects on intrapulmonary and extrapulmonary host defense through divergent TLR response phenotypes.
Journal of immunology (Baltimore, Md. : 1950)
Madenspacher JH,Draper DW,Smoak KA,Li H,Griffiths GL,Suratt BT,Wilson MD,Rudel LL,Fessler MB
Sun Aug 01 00:00:00 EDT 2010
Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation.
Blood
Mangalmurti NS,Xiong Z,Hulver M,Ranganathan M,Liu XH,Oriss T,Fitzpatrick M,Rubin M,Triulzi D,Choi A,Lee JS
Thu Jan 29 00:00:00 EST 2009
Critical role of phospholipase Cgamma2 in integrin and Fc receptor-mediated neutrophil functions and the effector phase of autoimmune arthritis.
The Journal of experimental medicine
Jakus Z,Simon E,Frommhold D,Sperandio M,Mócsai A
Mon Mar 16 00:00:00 EDT 2009
A protective role for ELR+ chemokines during acute viral encephalomyelitis.
PLoS pathogens
Hosking MP,Liu L,Ransohoff RM,Lane TE
Sun Nov 01 00:00:00 EDT 2009
CXCR2 mediates the recruitment of endothelial progenitor cells during allergic airways remodeling.
Stem cells (Dayton, Ohio)
Jones CP,Pitchford SC,Lloyd CM,Rankin SM
Tue Dec 01 00:00:00 EST 2009
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
The role of CXCR2/CXCR2 ligand biological axis in renal cell carcinoma.
Journal of immunology (Baltimore, Md. : 1950)
Mestas J,Burdick MD,Reckamp K,Pantuck A,Figlin RA,Strieter RM
Sat Oct 15 00:00:00 EDT 2005
Chemokine-cytokine cross-talk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathway.
The Journal of biological chemistry
Chandrasekar B,Melby PC,Sarau HM,Raveendran M,Perla RP,Marelli-Berg FM,Dulin NO,Singh IS
Fri Feb 14 00:00:00 EST 2003
CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Michalec L,Choudhury BK,Postlethwait E,Wild JS,Alam R,Lett-Brown M,Sur S
Tue Jan 15 00:00:00 EST 2002
