Product References
Plexin-A4 Mediates Cytotoxic T-cell Trafficking and Exclusion in Cancer.
Cancer immunology research
Celus W,Oliveira AI,Rivis S,Van Acker HH,Landeloos E,Serneels J,Cafarello ST,Van Herck Y,Mastrantonio R,Köhler A,Garg AD,Flamand V,Tamagnone L,Marine JC,Di Matteo M,Costa BM,Bechter O,Mazzone M
250-18 was used in In vitro experiments to show that expression of the axon guidance molecule Plexin-A4 (Plxna4) in cytotoxic T cells (CTLs), especially in effector/memory CD8+ T cells, is induced upon T-cell activation, sustained in the circulation, but reduced when entering the tumor bed and that upon deletion of Plxna4, CTLs acquire improved homing capacity to the lymph nodes and to the tumor.
Sat Jan 01 00:00:00 EST 2022
Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs.
Nature communications
Pein M,Insua-Rodríguez J,Hongu T,Riedel A,Meier J,Wiedmann L,Decker K,Essers MAG,Sinn HP,Spaich S,Sütterlin M,Schneeweiss A,Trumpp A,Oskarsson T
Fri Mar 20 00:00:00 EDT 2020
CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
Scientific reports
Joutoku Z,Onodera T,Matsuoka M,Homan K,Momma D,Baba R,Hontani K,Hamasaki M,Matsubara S,Hishimura R,Iwasaki N
Tue Mar 26 00:00:00 EDT 2019
Sipa1 deficiency unleashes a host-immune mechanism eradicating chronic myelogenous leukemia-initiating cells.
Nature communications
Xu Y,Ikeda S,Sumida K,Yamamoto R,Tanaka H,Minato N
Fri Mar 02 00:00:00 EST 2018
Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis.
The Journal of clinical investigation
Koyanagi N,Imai T,Shindo K,Sato A,Fujii W,Ichinohe T,Takemura N,Kakuta S,Uematsu S,Kiyono H,Maruzuru Y,Arii J,Kato A,Kawaguchi Y
Mon Oct 02 00:00:00 EDT 2017
Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis.
The Journal of clinical investigation
Koyanagi N,Imai T,Shindo K,Sato A,Fujii W,Ichinohe T,Takemura N,Kakuta S,Uematsu S,Kiyono H,Maruzuru Y,Arii J,Kato A,Kawaguchi Y
Mon Oct 02 00:00:00 EDT 2017
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Scientific reports
Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S
Tue Jun 27 00:00:00 EDT 2017
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Scientific reports
Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW
Wed Nov 22 00:00:00 EST 2017
pMHC affinity controls duration of CD8+ T cell-DC interactions and imprints timing of effector differentiation versus expansion.
The Journal of experimental medicine
Ozga AJ,Moalli F,Abe J,Swoger J,Sharpe J,Zehn D,Kreutzfeldt M,Merkler D,Ripoll J,Stein JV
Mon Nov 14 00:00:00 EST 2016
CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2.
Nature communications
Shin H,Kumamoto Y,Gopinath S,Iwasaki A
Wed Nov 09 00:00:00 EST 2016
CCR6-dependent positioning of memory B cells is essential for their ability to mount a recall response to antigen.
Journal of immunology (Baltimore, Md. : 1950)
Elgueta R,Marks E,Nowak E,Menezes S,Benson M,Raman VS,Ortiz C,O'Connell S,Hess H,Lord GM,Noelle R
Thu Jan 15 00:00:00 EST 2015
CXCL9 causes heterologous desensitization of CXCL12-mediated memory T lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950)
Giegold O,Ogrissek N,Richter C,Schröder M,Herrero San Juan M,Pfeilschifter JM,Radeke HH
Mon Apr 01 00:00:00 EDT 2013
IL-27 receptor signaling regulates CD4+ T cell chemotactic responses during infection.
Journal of immunology (Baltimore, Md. : 1950)
Gwyer Findlay E,Villegas-Mendez A,de Souza JB,Inkson CA,Shaw TN,Saris CJ,Hunter CA,Riley EM,Couper KN
Wed May 01 00:00:00 EDT 2013
A vaccine strategy that protects against genital herpes by establishing local memory T cells.
Nature
Shin H,Iwasaki A
Thu Nov 15 00:00:00 EST 2012
Gene profile of chemokines on hepatic stellate cells of schistosome-infected mice and antifibrotic roles of CXCL9/10 on liver non-parenchymal cells.
PloS one
Liang YJ,Luo J,Lu Q,Zhou Y,Wu HW,Zheng D,Ren YY,Sun KY,Wang Y,Zhang ZS
Mon Feb 11 00:00:00 EST 2013
Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration.
The Journal of experimental medicine
Kurachi M,Kurachi J,Suenaga F,Tsukui T,Abe J,Ueha S,Tomura M,Sugihara K,Takamura S,Kakimi K,Matsushima K
Mon Aug 01 00:00:00 EDT 2011
Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis.
Proceedings of the National Academy of Sciences of the United States of America
Crawford MA,Lowe DE,Fisher DJ,Stibitz S,Plaut RD,Beaber JW,Zemansky J,Mehrad B,Glomski IJ,Strieter RM,Hughes MA
Tue Oct 11 00:00:00 EDT 2011
Chemokines and inflammatory mediators interact to regulate adult murine neural precursor cell proliferation, survival and differentiation.
PloS one
Turbic A,Leong SY,Turnley AM
Fri Feb 10 00:00:00 EST 2012
Mesenchymal stem cells exhibit firm adhesion, crawling, spreading and transmigration across aortic endothelial cells: effects of chemokines and shear.
PloS one
Chamberlain G,Smith H,Rainger GE,Middleton J
Thu Jan 26 00:00:00 EST 2012
Interferon-inducible CXC chemokines directly contribute to host defense against inhalational anthrax in a murine model of infection.
PLoS pathogens
Crawford MA,Burdick MD,Glomski IJ,Boyer AE,Barr JR,Mehrad B,Strieter RM,Hughes MA
Thu Nov 18 00:00:00 EST 2010
A novel recombinant fusion protein encoding a 20-amino acid residue of the third extracellular (E3) domain of CCR2 neutralizes the biological activity of CCL2.
Journal of immunology (Baltimore, Md. : 1950)
Izhak L,Wildbaum G,Zohar Y,Anunu R,Klapper L,Elkeles A,Seagal J,Yefenof E,Ayalon-Soffer M,Karin N
Wed Jul 01 00:00:00 EDT 2009
The chemokine receptor CCR5 plays a key role in the early memory CD8+ T cell response to respiratory virus infections.
Immunity
Kohlmeier JE,Miller SC,Smith J,Lu B,Gerard C,Cookenham T,Roberts AD,Woodland DL
Fri Jul 18 00:00:00 EDT 2008
Structure and function of A41, a vaccinia virus chemokine binding protein.
PLoS pathogens
Bahar MW,Kenyon JC,Putz MM,Abrescia NG,Pease JE,Wise EL,Stuart DI,Smith GL,Grimes JM
Tue Jan 01 00:00:00 EST 2008
CXCL9 and CXCL10 expression are critical for control of genital herpes simplex virus type 2 infection through mobilization of HSV-specific CTL and NK cells to the nervous system.
Journal of immunology (Baltimore, Md. : 1950)
Thapa M,Welner RS,Pelayo R,Carr DJ
Tue Jan 15 00:00:00 EST 2008
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Journal of immune based therapies and vaccines
Sakthivel SK,Singh UP,Singh S,Taub DD,Novakovic KR,Lillard JW
Tue Oct 28 00:00:00 EDT 2008
NK cells stimulate recruitment of CXCR3+ T cells to the brain during Plasmodium berghei-mediated cerebral malaria.
Journal of immunology (Baltimore, Md. : 1950)
Hansen DS,Bernard NJ,Nie CQ,Schofield L
Tue May 01 00:00:00 EDT 2007
Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling.
The Journal of biological chemistry
Thompson BD,Jin Y,Wu KH,Colvin RA,Luster AD,Birnbaumer L,Wu MX
Fri Mar 30 00:00:00 EDT 2007
Dengue virus induces expression of CXC chemokine ligand 10/IFN-gamma-inducible protein 10, which competitively inhibits viral binding to cell surface heparan sulfate.
Journal of immunology (Baltimore, Md. : 1950)
Chen JP,Lu HL,Lai SL,Campanella GS,Sung JM,Lu MY,Wu-Hsieh BA,Lin YL,Lane TE,Luster AD,Liao F
Fri Sep 01 00:00:00 EDT 2006
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
Pivotal role of CXCR3 in melanoma cell metastasis to lymph nodes.
Cancer research
Kawada K,Sonoshita M,Sakashita H,Takabayashi A,Yamaoka Y,Manabe T,Inaba K,Minato N,Oshima M,Taketo MM
Tue Jun 01 00:00:00 EDT 2004
