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Product Details
RP-87737
Product Specifications
Species
Mouse
Expression System
E. coli
Amino acid sequence
MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ
Molecular weight
18.6 kDa
Class
Recombinant
Type
Protein
Purity
≥95% by SDS-PAGE
Endotoxin concentration
≤0.1 EU/µg
Activity
ED50 ≤10 ng/mL; determined by the dose-dependent proliferation of OCI-AML5 cells.
Conjugate
Form
Lyophilized
Concentration
0.1 mg/mL
Purification
purified
Storage buffer
10mM sodium phosphate, pH 7.5
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Animal Origin Free
Reconstitute with 0.1 mg/mL sterile water
Target Information
FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Flt 3 ligand; Flt3 L; Flt3 ligand; Fms-related tyrosine kinase 3 ligand; H-FLT-3-L; M-FLT-3-L; SL cytokine
Gene Aliases: Flt3l; Flt3lg; Ly72L
UniProt ID: (Mouse) P49772
Entrez Gene ID: (Mouse) 14256
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