Product References
A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise.
Cell stem cell
Gadomski S,Fielding C,García-García A,Korn C,Kapeni C,Ashraf S,Villadiego J,Toro RD,Domingues O,Skepper JN,Michel T,Zimmer J,Sendtner R,Dillon S,Poole KES,Holdsworth G,Sendtner M,Toledo-Aral JJ,De Bari C,McCaskie AW,Robey PG,Méndez-Ferrer S
450-44 was used in In vitro experiments to uncover a cholinergic neuro-osteocyte interface that regulates skeletogenesis and skeletal turnover through bone-anabolic effects.
Thu Apr 07 00:00:00 EDT 2022
Analysis of mouse intestinal organoid culture with conditioned media isolated from mucosal enteric glial cells.
STAR protocols
Baghdadi MB,Kim TH
450-44 was used in Cell Culture to provide a protocol which describes the isolation and culture of 3D intestinal crypt organoids with stromal niche cells which can be used to study the mechanisms of stem cell interaction with other stromal niche cell types such as mesenchymal cells and innate immune cells.
Fri Jun 17 00:00:00 EDT 2022
ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function.
Cell reports
Baron DM,Fenton AR,Saez-Atienzar S,Giampetruzzi A,Sreeram A,Keagle PJ,Doocy VR,Smith NJ,Danielson EW,Andresano M,McCormack MC,Garcia J,Bercier V,Van Den Bosch L,Brent JR,Fallini C,Traynor BJ,Holzbaur ELF,Landers JE
450-44 was used in Cell Culture to support the hypothesis that causative ALS mutations result in a toxic gain of function in the intracellular motor KIF5A that disrupts intracellular trafficking and neuronal homeostasis.
Tue Apr 05 00:00:00 EDT 2022
Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy.
Proceedings of the National Academy of Sciences of the United States of America
Hensel N,Cieri F,Santonicola P,Tapken I,Schüning T,Taiana M,Pagliari E,Joseph A,Fischer S,Heidrich N,Brinkmann H,Kubinski S,Bergmann AK,Richter MF,Jung K,Corti S,Di Schiavi E,Claus P
Tue May 04 00:00:00 EDT 2021
PML-NB-dependent type I interferon memory results in a restricted form of HSV latency.
EMBO reports
Suzich JB,Cuddy SR,Baidas H,Dochnal S,Ke E,Schinlever AR,Babnis A,Boutell C,Cliffe AR
450-44 was used in Cell Culture to demonstrate that viral genomes possess a memory of the IFN response during de novo infection, which results in differential subnuclear positioning and ultimately restricts the ability of genomes to reactivate.
Mon Sep 06 00:00:00 EDT 2021
Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine.
Stem cells translational medicine
Yuan H,Hu H,Chen R,Mu W,Wang L,Li Y,Chen Y,Ding X,Xi Y,Mao S,Jiang M,Chen J,He Y,Wang L,Dong Y,Tou J,Chen W
Tue Jun 01 00:00:00 EDT 2021
Sertoli cell-derived exosomal MicroRNA-486-5p regulates differentiation of spermatogonial stem cell through PTEN in mice.
Journal of cellular and molecular medicine
Li Q,Li H,Liang J,Mei J,Cao Z,Zhang L,Luo J,Tang Y,Huang R,Xia H,Zhang Q,Xiang Q,Yang Y,Huang Y
Thu Apr 01 00:00:00 EDT 2021
The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.
Cell reports
Walter J,Bolognin S,Poovathingal SK,Magni S,Gérard D,Antony PMA,Nickels SL,Salamanca L,Berger E,Smits LM,Grzyb K,Perfeito R,Hoel F,Qing X,Ohnmacht J,Bertacchi M,Jarazo J,Ignac T,Monzel AS,Gonzalez-Cano L,Krüger R,Sauter T,Studer M,de Almeida LP,Tronstad KJ,Sinkkonen L,Skupin A,Schwamborn JC
Tue Oct 19 00:00:00 EDT 2021
Circ-Hdgfrp3 shuttles along neurites and is trapped in aggregates formed by ALS-associated mutant FUS.
iScience
D'Ambra E,Santini T,Vitiello E,D'Uva S,Silenzi V,Morlando M,Bozzoni I
450-44 was used in In vitro experiments to investigate Circ-Hdgfrp3 and its association with motor neurons carrying ALS-associated FUS mutations.
Fri Dec 17 00:00:00 EST 2021
Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells.
Communications biology
Rore H,Owen N,Piña-Aguilar RE,Docherty K,Sekido R
Mon Jun 28 00:00:00 EDT 2021
Development of an objective index, neural activity score (NAS), reveals neural network ontogeny and treatment effects on microelectrode arrays.
Scientific reports
Passaro AP,Aydin O,Saif MTA,Stice SL
Tue Apr 27 00:00:00 EDT 2021
Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough.
Cell
Ruhl CR,Pasko BL,Khan HS,Kindt LM,Stamm CE,Franco LH,Hsia CC,Zhou M,Davis CR,Qin T,Gautron L,Burton MD,Mejia GL,Naik DK,Dussor G,Price TJ,Shiloh MU
Thu Apr 16 00:00:00 EDT 2020
USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway.
Proceedings of the National Academy of Sciences of the United States of America
Zhang T,Periz G,Lu YN,Wang J
Tue Nov 10 00:00:00 EST 2020
Acute stress disrupts intestinal homeostasis via GDNF-RET.
Cell proliferation
Lin L,Feng B,Zhou R,Liu Y,Li L,Wang K,Yu Y,Liu C,Long X,Gu X,Li B,Wang X,Yang X,Cong Y,Zuo X,Li Y
Thu Oct 01 00:00:00 EDT 2020
Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels.
Frontiers in cellular neuroscience
Sleigh JN,Mech AM,Aktar T,Zhang Y,Schiavo G
450-44 was used in Cell Culture to study the anatomy and function of the Charcot-Marie-Tooth disease type 2D (CMT2D) sensory nervous system in mutant Gars mice.
Sun Jan 10 00:00:00 EST 2021
Comparison of different in vitro differentiation conditions for murine female germline stem cells.
Cell proliferation
Zou K,Wang J,Bi H,Zhang Y,Tian X,Tian N,Ma W,Wu J
Tue Jan 01 00:00:00 EST 2019
The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing.
The Journal of biological chemistry
Tischbein M,Baron DM,Lin YC,Gall KV,Landers JE,Fallini C,Bosco DA
Fri Jun 28 00:00:00 EDT 2019
Stimulation of noradrenergic transmission by reboxetine is beneficial for a mouse model of progressive parkinsonism.
Scientific reports
Kreiner G,Rafa-Zabłocka K,Barut J,Chmielarz P,Kot M,Bagińska M,Parlato R,Daniel WA,Nalepa I
Wed Mar 27 00:00:00 EDT 2019
Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression.
Scientific reports
Makino Y,Jensen NH,Yokota N,Rossner MJ,Akiyama H,Shirahige K,Okada Y
Mon Apr 15 00:00:00 EDT 2019
Long non-coding RNA repertoire and open chromatin regions constitute midbrain dopaminergic neuron - specific molecular signatures.
Scientific reports
Gendron J,Colace-Sauty C,Beaume N,Cartonnet H,Guegan J,Ulveling D,Pardanaud-Glavieux C,Moszer I,Cheval H,Ravassard P
Tue Feb 05 00:00:00 EST 2019
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability.
Neuron
Dawes JM,Weir GA,Middleton SJ,Patel R,Chisholm KI,Pettingill P,Peck LJ,Sheridan J,Shakir A,Jacobson L,Gutierrez-Mecinas M,Galino J,Walcher J,Kühnemund J,Kuehn H,Sanna MD,Lang B,Clark AJ,Themistocleous AC,Iwagaki N,West SJ,Werynska K,Carroll L,Trendafilova T,Menassa DA,Giannoccaro MP,Coutinho E,Cervellini I,Tewari D,Buckley C,Leite MI,Wildner H,Zeilhofer HU,Peles E,Todd AJ,McMahon SB,Dickenson AH,Lewin GR,Vincent A,Bennett DL
Wed Feb 21 00:00:00 EST 2018
Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy.
Scientific reports
Gonçalves IDCG,Brecht J,Thelen MP,Rehorst WA,Peters M,Lee HJ,Motameny S,Torres-Benito L,Ebrahimi-Fakhari D,Kononenko NL,Altmüller J,Vilchez D,Sahin M,Wirth B,Kye MJ
Mon May 21 00:00:00 EDT 2018
FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche.
Stem cell reports
Masaki K,Sakai M,Kuroki S,Jo JI,Hoshina K,Fujimori Y,Oka K,Amano T,Yamanaka T,Tachibana M,Tabata Y,Shiozawa T,Ishizuka O,Hochi S,Takashima S
Tue Jun 05 00:00:00 EDT 2018
Proteomics Reveals Scope of Mycolactone-mediated Sec61 Blockade and Distinctive Stress Signature.
Molecular & cellular proteomics : MCP
Morel JD,Paatero AO,Wei J,Yewdell JW,Guenin-Macé L,Van Haver D,Impens F,Pietrosemoli N,Paavilainen VO,Demangel C
Sat Sep 01 00:00:00 EDT 2018
Oxaliplatin induces pH acidification in dorsal root ganglia neurons.
Scientific reports
Riva B,Dionisi M,Potenzieri A,Chiorazzi A,Cordero-Sanchez C,Rigolio R,Carozzi VA,Lim D,Cavaletti G,Marmiroli P,Distasi C,Genazzani AA
Wed Oct 10 00:00:00 EDT 2018
Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids.
Translational psychiatry
Srikanth P,Lagomarsino VN,Muratore CR,Ryu SC,He A,Taylor WM,Zhou C,Arellano M,Young-Pearse TL
Thu Apr 12 00:00:00 EDT 2018
SiO2 nanoparticles modulate the electrical activity of neuroendocrine cells without exerting genomic effects.
Scientific reports
Distasi C,Ruffinatti FA,Dionisi M,Antoniotti S,Gilardino A,Croci G,Riva B,Bassino E,Alberto G,Castroflorio E,Incarnato D,Morandi E,Martra G,Oliviero S,Munaron L,Lovisolo D
Fri Feb 09 00:00:00 EST 2018
High content image analysis reveals function of miR-124 upstream of Vimentin in regulating motor neuron mitochondria.
Scientific reports
Yardeni T,Fine R,Joshi Y,Gradus-Pery T,Kozer N,Reichenstein I,Yanowski E,Nevo S,Weiss-Tishler H,Eisenberg-Bord M,Shalit T,Plotnikov A,Barr HM,Perlson E,Hornstein E
Mon Jan 08 00:00:00 EST 2018
Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons.
Neuron
Welsbie DS,Mitchell KL,Jaskula-Ranga V,Sluch VM,Yang Z,Kim J,Buehler E,Patel A,Martin SE,Zhang PW,Ge Y,Duan Y,Fuller J,Kim BJ,Hamed E,Chamling X,Lei L,Fraser IDC,Ronai ZA,Berlinicke CA,Zack DJ
Wed Jun 21 00:00:00 EDT 2017
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells.
eLife
Sternfeld MJ,Hinckley CA,Moore NJ,Pankratz MT,Hilde KL,Driscoll SP,Hayashi M,Amin ND,Bonanomi D,Gifford WD,Sharma K,Goulding M,Pfaff SL
450-44 was used in Cell Culture to investigate excitatory and inhibitory spinal neuron circuits.
Tue Feb 14 00:00:00 EST 2017
In Vitro Propagation and Branching Morphogenesis from Single Ureteric Bud Cells.
Stem cell reports
Yuri S,Nishikawa M,Yanagawa N,Jo OD,Yanagawa N
Tue Feb 14 00:00:00 EST 2017
Exon Skipping in the RET Gene Encodes Novel Isoforms That Differentially Regulate RET Protein Signal Transduction.
The Journal of biological chemistry
Gabreski NA,Vaghasia JK,Novakova SS,McDonald NQ,Pierchala BA
Fri Jul 29 00:00:00 EDT 2016
Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis.
The Journal of biological chemistry
Lu L,Zheng L,Si Y,Luo W,Dujardin G,Kwan T,Potochick NR,Thompson SR,Schneider DA,King PH
Fri Nov 14 00:00:00 EST 2014
Functional profiling of neurons through cellular neuropharmacology.
Proceedings of the National Academy of Sciences of the United States of America
Teichert RW,Smith NJ,Raghuraman S,Yoshikami D,Light AR,Olivera BM
Tue Jan 31 00:00:00 EST 2012
Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.
Stem cells (Dayton, Ohio)
Ventelä S,Mäkelä JA,Kulmala J,Westermarck J,Toppari J
Tue May 01 00:00:00 EDT 2012
Involvement of Tyr1472 phosphorylation of NMDA receptor NR2B subunit in postherpetic neuralgia in model mice.
Molecular pain
Unezaki S,Sasaki A,Mabuchi T,Matsumura S,Katano T,Nakazawa T,Nishio N,Andoh T,Yamamoto T,Nakatsuka T,Kuraishi Y,Ito S
Tue Aug 21 00:00:00 EDT 2012
Schwann cells migrate along axons in the absence of GDNF signaling.
BMC neuroscience
Heermann S,Spittau B,Zajzon K,Schwab MH,Krieglstein K
Fri Aug 03 00:00:00 EDT 2012
