Product References
ATP7B gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a mouse model of Wilson's disease.
Hepatology (Baltimore, Md.)
Cai H,Cheng X,Wang XP
Sat Oct 01 00:00:00 EDT 2022
SOX9 in prostate cancer is upregulated by cancer-associated fibroblasts to promote tumor progression through HGF/c-Met-FRA1 signaling.
The FEBS journal
Qin H,Yang Y,Jiang B,Pan C,Chen W,Diao W,Ding M,Cao W,Zhang Z,Chen M,Gao J,Zhao X,Qiu X,Guo H
315-23 was used in Sample Preparation (WB) to investigate mechanisms of SOX9 and Pca biomarker in prostate cancer prognosis.
Wed Sep 01 00:00:00 EDT 2021
Hepatocyte growth factor overexpression promotes osteoclastogenesis and exacerbates bone loss in CIA mice.
Journal of orthopaedic translation
Huang C,Zheng Y,Bai J,Shi C,Shi X,Shan H,Zhou X
315-23 was used in Cell Culture to study effect of hepatocyte growth factor (HGF) on bone metabolism in rheumatoid arthritis (RA).
Mon Mar 01 00:00:00 EST 2021
SILAC proteomics implicates SOCS1 in modulating cellular macromolecular complexes and the ubiquitin conjugating enzyme UBE2D involved in MET receptor tyrosine kinase downregulation.
Biochimie
Santharam MA,Shukla A,Ihsan AU,Cloutier M,Levesque D,Ramanathan S,Boisvert FM,Ilangumaran S
315-23 was used in Cell Culture to suggest that SOCS1, induced by cytokines, growth factors and diverse other stimuli, has the potential to dynamically modulate of large macromolecular regulatory complexes to help maintain cellular homeostasis.
Mon Mar 01 00:00:00 EST 2021
Mouse parotid salivary gland organoids for the in vitro study of stem cell radiation response.
Oral diseases
Serrano Martinez P,Cinat D,van Luijk P,Baanstra M,de Haan G,Pringle S,Coppes RP
Fri Jan 01 00:00:00 EST 2021
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells.
Cell adhesion & migration
Roncato F,Regev O,Yadav SK,Alon R
315-23 was used in In vitro experiments to investigate microtubule turnover in epithelial barriers.
Wed Dec 01 00:00:00 EST 2021
Autophagy Is Required for Hepatic Differentiation of Hepatic Progenitor Cells via Wnt Signaling Pathway.
BioMed research international
Zeng J,Jing Y,Wu Q,Zeng J,Wei L,Liu J
315-23 was used in Sample Preparation (Western Blotting) to demonstrate that autophagy regulates hepatic differentiation of hepatic progenitor cells through Wnt signaling pathway.
Tue May 25 00:00:00 EDT 2021
Autophagy Is Required for Hepatic Differentiation of Hepatic Progenitor Cells via Wnt Signaling Pathway.
BioMed research international
Zeng J,Jing Y,Wu Q,Zeng J,Wei L,Liu J
315-23 was used in Sample Preparation (Western Blotting) to demonstrate that autophagy regulates hepatic differentiation of hepatic progenitor cells through Wnt signaling pathway.
Tue May 25 00:00:00 EDT 2021
Homeostatic mini-intestines through scaffold-guided organoid morphogenesis.
Nature
Nikolaev M,Mitrofanova O,Broguiere N,Geraldo S,Dutta D,Tabata Y,Elci B,Brandenberg N,Kolotuev I,Gjorevski N,Clevers H,Lutolf MP
Tue Sep 01 00:00:00 EDT 2020
Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth.
Cell
Yao M,Ventura PB,Jiang Y,Rodriguez FJ,Wang L,Perry JSA,Yang Y,Wahl K,Crittenden RB,Bennett ML,Qi L,Gong CC,Li XN,Barres BA,Bender TP,Ravichandran KS,Janes KA,Eberhart CG,Zong H
Thu Feb 06 00:00:00 EST 2020
Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.
The Journal of clinical investigation
Hyun J,Sun Z,Ahmadi AR,Bangru S,Chembazhi UV,Du K,Chen T,Tsukamoto H,Rusyn I,Kalsotra A,Diehl AM
Wed Apr 01 00:00:00 EDT 2020
Cooperation Between MYC and β-Catenin in Liver Tumorigenesis Requires Yap/Taz.
Hepatology (Baltimore, Md.)
Bisso A,Filipuzzi M,Gamarra Figueroa GP,Brumana G,Biagioni F,Doni M,Ceccotti G,Tanaskovic N,Morelli MJ,Pendino V,Chiacchiera F,Pasini D,Olivero D,Campaner S,Sabò A,Amati B
315-23 was used in Cell Culture to investigate signalling and mouse models of liver carcinogenesis and CTNNB1.
Thu Oct 01 00:00:00 EDT 2020
Genetically engineered distal airway stem cell transplantation protects mice from pulmonary infection.
EMBO molecular medicine
Zhou YQ,Shi Y,Yang L,Sun YF,Han YF,Zhao ZX,Wang YJ,Liu Y,Ma Y,Zhang T,Ren T,Dale TP,Forsyth NR,Jin FG,Qu JM,Zuo W,Xu JF
Thu Jan 09 00:00:00 EST 2020
Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.
Cell death & disease
de la Fuente S,Sansa A,Hidalgo I,Vivancos N,Romero-Guevara R,Garcera A,Soler RM
Thu Jun 25 00:00:00 EDT 2020
Drug-Induced Naïve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic β-Cell Lineage.
Journal of clinical medicine
Kiyokawa Y,Sato M,Noguchi H,Inada E,Iwase Y,Kubota N,Sawami T,Terunuma M,Maeda T,Hayasaki H,Saitoh I
315-23 was used in Cell Culture to study whether naïve stem cells (NSCs) can be efficiently induced to form potentially pancreatic β cells after being subjected to an in vitro protocol.
Wed Sep 02 00:00:00 EDT 2020
Mechano-modulatory synthetic niches for liver organoid derivation.
Nature communications
Sorrentino G,Rezakhani S,Yildiz E,Nuciforo S,Heim MH,Lutolf MP,Schoonjans K
Fri Jul 10 00:00:00 EDT 2020
Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression.
Scientific reports
Badu-Mensah A,Guo X,McAleer CW,Rumsey JW,Hickman JJ
Mon Aug 31 00:00:00 EDT 2020
LGR5 marks targetable tumor-initiating cells in mouse liver cancer.
Nature communications
Cao W,Li M,Liu J,Zhang S,Noordam L,Verstegen MMA,Wang L,Ma B,Li S,Wang W,Bolkestein M,Doukas M,Chen K,Ma Z,Bruno M,Sprengers D,Kwekkeboom J,van der Laan LJW,Smits R,Peppelenbosch MP,Pan Q
Thu Apr 23 00:00:00 EDT 2020
Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment.
Neuron
Geraghty AC,Gibson EM,Ghanem RA,Greene JJ,Ocampo A,Goldstein AK,Ni L,Yang T,Marton RM,Paşca SP,Greenberg ME,Longo FM,Monje M
Wed Jul 17 00:00:00 EDT 2019
Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11.
American journal of physiology. Cell physiology
Katsumi T,Guicciardi ME,Azad A,Bronk SF,Krishnan A,Gores GJ
Tue Oct 01 00:00:00 EDT 2019
SIRT3 elicited an anti-Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis.
Cancer medicine
Xu L,Li Y,Zhou L,Dorfman RG,Liu L,Cai R,Jiang C,Tang D,Wang Y,Zou X,Wang L,Zhang M
Wed May 01 00:00:00 EDT 2019
Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta.
Stem cell reports
Haider S,Meinhardt G,Saleh L,Kunihs V,Gamperl M,Kaindl U,Ellinger A,Burkard TR,Fiala C,Pollheimer J,Mendjan S,Latos PA,Knöfler M
Tue Aug 14 00:00:00 EDT 2018
ZBTB20 regulates EGFR expression and hepatocyte proliferation in mouse liver regeneration.
Cell death & disease
Zhang H,Shi JH,Jiang H,Wang K,Lu JY,Jiang X,Ma X,Chen YX,Ren AJ,Zheng J,Xie Z,Guo S,Xu X,Zhang WJ
Tue May 01 00:00:00 EDT 2018
Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18.
Hepatology (Baltimore, Md.)
Ravà M,D'Andrea A,Doni M,Kress TR,Ostuni R,Bianchi V,Morelli MJ,Collino A,Ghisletti S,Nicoli P,Recordati C,Iascone M,Sonzogni A,D'Antiga L,Shukla R,Faulkner GJ,Natoli G,Campaner S,Amati B
Mon May 01 00:00:00 EDT 2017
The role of lncRNA MALAT1 in the regulation of hepatocyte proliferation during liver regeneration.
International journal of molecular medicine
Li C,Chang L,Chen Z,Liu Z,Wang Y,Ye Q
315-23 was used in Cell Culture to study the biological role of long non-coding RNA (lncRNA) metastasis‚associated lung adenocarcinoma transcript 1 (MALAT1) in liver regeneration to show that MALAT1 is a critical molecule for liver regeneration.
Wed Feb 01 00:00:00 EST 2017
Adult Mouse Liver Contains Two Distinct Populations of Cholangiocytes.
Stem cell reports
Li B,Dorrell C,Canaday PS,Pelz C,Haft A,Finegold M,Grompe M
Tue Aug 08 00:00:00 EDT 2017
Transposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.
Proceedings of the National Academy of Sciences of the United States of America
Kodama T,Newberg JY,Kodama M,Rangel R,Yoshihara K,Tien JC,Parsons PH,Wu H,Finegold MJ,Copeland NG,Jenkins NA
Tue Jun 14 00:00:00 EDT 2016
A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion.
The Journal of cell biology
McConnell RE,Edward van Veen J,Vidaki M,Kwiatkowski AV,Meyer AS,Gertler FB
Mon Apr 25 00:00:00 EDT 2016
CCAAT/enhancer binding protein beta protects muscle satellite cells from apoptosis after injury and in cancer cachexia.
Cell death & disease
Marchildon F,Fu D,Lala-Tabbert N,Wiper-Bergeron N
Thu Feb 25 00:00:00 EST 2016
PKN3 is the major regulator of angiogenesis and tumor metastasis in mice.
Scientific reports
Mukai H,Muramatsu A,Mashud R,Kubouchi K,Tsujimoto S,Hongu T,Kanaho Y,Tsubaki M,Nishida S,Shioi G,Danno S,Mehruba M,Satoh R,Sugiura R
Fri Jan 08 00:00:00 EST 2016
Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose.
PloS one
Saitoh I,Sato M,Soda M,Inada E,Iwase Y,Murakami T,Ohshima H,Hayasaki H,Noguchi H
315-23 was used in Cell Culture to study how glucose-sensitive insulin-producing cells are successsfully generated by transfecting primary pancreatic cells from non-obese diabetic (NOD) mice (aged 6 months old) with a plasmid harboring the cDNAs for Oct-3/4, Sox2, Klf4, and c-Myc.
Wed Nov 20 00:00:00 EST 2019
Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro.
Nature protocols
Chal J,Al Tanoury Z,Hestin M,Gobert B,Aivio S,Hick A,Cherrier T,Nesmith AP,Parker KK,Pourquié O
Sat Oct 01 00:00:00 EDT 2016
Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy.
Nature biotechnology
Chal J,Oginuma M,Al Tanoury Z,Gobert B,Sumara O,Hick A,Bousson F,Zidouni Y,Mursch C,Moncuquet P,Tassy O,Vincent S,Miyanari A,Bera A,Garnier JM,Guevara G,Hestin M,Kennedy L,Hayashi S,Drayton B,Cherrier T,Gayraud-Morel B,Gussoni E,Relaix F,Tajbakhsh S,Pourquié O
Tue Sep 01 00:00:00 EDT 2015
Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release.
Immunity
Komarowska I,Coe D,Wang G,Haas R,Mauro C,Kishore M,Cooper D,Nadkarni S,Fu H,Steinbruchel DA,Pitzalis C,Anderson G,Bucy P,Lombardi G,Breckenridge R,Marelli-Berg FM
Tue Jun 16 00:00:00 EDT 2015
The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities.
PloS one
Chen X,Song F,Jhamb D,Li J,Bottino MC,Palakal MJ,Stocum DL
315-23 was used in In vitro experiments to study the ability of the axolotl (Ambystoma mexicanum) fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS) scaffold, with or without incorporated growth factor combinations or tissue protein extract.
Mon Apr 25 00:00:00 EDT 2016
The Axolotl Fibula as a Model for the Induction of Regeneration across Large Segment Defects in Long Bones of the Extremities.
PloS one
Chen X,Song F,Jhamb D,Li J,Bottino MC,Palakal MJ,Stocum DL
315-23 was used in In vitro experiments to study the ability of the axolotl (Ambystoma mexicanum) fibula to regenerate across segment defects of different size in the absence of intervention or after implant of a unique 8-braid pig small intestine submucosa (SIS) scaffold, with or without incorporated growth factor combinations or tissue protein extract.
Mon Apr 25 00:00:00 EDT 2016
Tumour-promoting role of SOCS1 in colorectal cancer cells.
Scientific reports
Tobelaim WS,Beaurivage C,Champagne A,Pomerleau V,Simoneau A,Chababi W,Yeganeh M,Thibault P,Klinck R,Carrier JC,Ferbeyre G,Ilangumaran S,Saucier C
Tue Sep 22 00:00:00 EDT 2015
Tumour-promoting role of SOCS1 in colorectal cancer cells.
Scientific reports
Tobelaim WS,Beaurivage C,Champagne A,Pomerleau V,Simoneau A,Chababi W,Yeganeh M,Thibault P,Klinck R,Carrier JC,Ferbeyre G,Ilangumaran S,Saucier C
Tue Sep 22 00:00:00 EDT 2015
Hippo pathway activity influences liver cell fate.
Cell
Yimlamai D,Christodoulou C,Galli GG,Yanger K,Pepe-Mooney B,Gurung B,Shrestha K,Cahan P,Stanger BZ,Camargo FD
Thu Jun 05 00:00:00 EDT 2014
A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infection.
Cell
Brandes M,Klauschen F,Kuchen S,Germain RN
Wed Jul 03 00:00:00 EDT 2013
1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit.
Cancer cell
Zhao W,Wang L,Han H,Jin K,Lin N,Guo T,Chen Y,Cheng H,Lu F,Fang W,Wang Y,Xing B,Zhang Z
Mon Apr 15 00:00:00 EDT 2013
CCAAT/enhancer binding protein beta is expressed in satellite cells and controls myogenesis.
Stem cells (Dayton, Ohio)
Marchildon F,Lala N,Li G,St-Louis C,Lamothe D,Keller C,Wiper-Bergeron N
Sat Dec 01 00:00:00 EST 2012
Met receptor tyrosine kinase signaling induces secretion of the angiogenic chemokine interleukin-8/CXCL8 in pancreatic cancer.
PloS one
Hill KS,Gaziova I,Harrigal L,Guerra YA,Qiu S,Sastry SK,Arumugam T,Logsdon CD,Elferink LA
Tue Mar 26 00:00:00 EDT 2013
Investigation of hepatoprotective activity of induced pluripotent stem cells in the mouse model of liver injury.
Journal of biomedicine & biotechnology
Chiang CH,Chang CC,Huang HC,Chen YJ,Tsai PH,Jeng SY,Hung SI,Hsieh JH,Huang HS,Chiou SH,Lee FY,Lee SD
Tue Oct 11 00:00:00 EDT 2011
