Product References
Protocols to generate and isolate mouse myogenic progenitors both in vitro and in vivo.
STAR protocols
Khateb M,Feng X,Dell'Orso S,Sartorelli V
250-19 was used in Cell Culture to describe here a procedure to obtain, dissect, and fluorescence-activated cell sorting (FACS)-isolate somitic cells from genetically labeled Pax7+/Cre; Rosa26YFP/+ embryos.
Fri Mar 17 00:00:00 EDT 2023
Transcriptomics, regulatory syntax, and enhancer identification in mesoderm-induced ESCs at single-cell resolution.
Cell reports
Khateb M,Perovanovic J,Ko KD,Jiang K,Feng X,Acevedo-Luna N,Chal J,Ciuffoli V,Genzor P,Simone J,Haase AD,Pourquié O,Dell'Orso S,Sartorelli V
250-19 was used in In vitro experiments to provide a resource for the discovery of genomic and transcriptional features of pluripotent, mesoderm-induced ESCs and ESC-derived cell lineages.
Tue Aug 16 00:00:00 EDT 2022
Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development.
Communications biology
Yan X,Managlia E,Zhao YY,Tan XD,De Plaen IG
250-19 was used in Cell Culture to suggest that defective IGF-1-production by neonatal macrophages impairs neonatal intestinal microvascular development and predisposes the intestine to necrotizing enterocolitis.
Wed Apr 06 00:00:00 EDT 2022
Peripheral B cells repress B-cell regeneration in aging through a TNF-α/IGFBP-1/IGF-1 immune-endocrine axis.
Blood
Dowery R,Benhamou D,Benchetrit E,Harel O,Nevelsky A,Zisman-Rozen S,Braun-Moscovici Y,Balbir-Gurman A,Avivi I,Shechter A,Berdnik D,Wyss-Coray T,Melamed D
Thu Nov 11 00:00:00 EST 2021
Intranasal mesenchymal stem cell therapy to boost myelination after encephalopathy of prematurity.
Glia
Vaes JEG,van Kammen CM,Trayford C,van der Toorn A,Ruhwedel T,Benders MJNL,Dijkhuizen RM,Möbius W,van Rijt SH,Nijboer CH
250-19 was used in Cell Culture to show that MSCs adapt their secretome after ex vivo exposure to dWMI milieu and identified several factors including IGF1, EGF, LIF, and IL11 that potently boost OL maturation.
Mon Mar 01 00:00:00 EST 2021
Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2'3'-Cyclic GMP-AMP and Cisplatin under Steady State and Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Chen X,Wang L,Cao L,Li T,Li Z,Sun Y,Ding J,Zhou C,Xie Y,Yue N,Nan J,Jia XM,Peng C,Li H,Yang J,Xiao H
Sat May 01 00:00:00 EDT 2021
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo.
Cell reports
Dignum T,Varnum-Finney B,Srivatsan SR,Dozono S,Waltner O,Heck AM,Ishida T,Nourigat-McKay C,Jackson DL,Rafii S,Trapnell C,Bernstein ID,Hadland B
Tue Sep 14 00:00:00 EDT 2021
Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells.
Communications biology
Rore H,Owen N,Piña-Aguilar RE,Docherty K,Sekido R
Mon Jun 28 00:00:00 EDT 2021
Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth.
Cell
Yao M,Ventura PB,Jiang Y,Rodriguez FJ,Wang L,Perry JSA,Yang Y,Wahl K,Crittenden RB,Bennett ML,Qi L,Gong CC,Li XN,Barres BA,Bender TP,Ravichandran KS,Janes KA,Eberhart CG,Zong H
Thu Feb 06 00:00:00 EST 2020
Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα-mediated lipid metabolism.
The Journal of clinical investigation
Zhou X,He C,Ren J,Dai C,Stevens SR,Wang Q,Zamler D,Shingu T,Yuan L,Chandregowda CR,Wang Y,Ravikumar V,Rao AU,Zhou F,Zheng H,Rasband MN,Chen Y,Lan F,Heimberger AB,Segal BM,Hu J
Fri May 01 00:00:00 EDT 2020
Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma.
Nature cancer
Tamayo-Orrego L,Gallo D,Racicot F,Bemmo A,Mohan S,Ho B,Salameh S,Hoang T,Jackson AP,Brown GW,Charron F
250-19 was used in Cell Culture to investigate the role of the developmental mitogen SHH in initiating carcinogenesis in the cells of origin: granule cell progenitors (GCPs).
Sat Aug 01 00:00:00 EDT 2020
Rate of Progression through a Continuum of Transit-Amplifying Progenitor Cell States Regulates Blood Cell Production.
Developmental cell
Li H,Natarajan A,Ezike J,Barrasa MI,Le Y,Feder ZA,Yang H,Ma C,Markoulaki S,Lodish HF
250-19 was used in Cell Culture to demonstrate a continuum of transcriptomic states in committed transit-amplifying erythropoietic progenitors, which correlates with a continuum of proliferative potentials in these cells.
Mon Apr 08 00:00:00 EDT 2019
Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration.
Proceedings of the National Academy of Sciences of the United States of America
Pristerà A,Blomeley C,Lopes E,Threlfell S,Merlini E,Burdakov D,Cragg S,Guillemot F,Ang SL
Tue Feb 26 00:00:00 EST 2019
Aging differentially modulates the Wnt pro-survival signalling pathways in vascular smooth muscle cells.
Aging cell
Brown BA,Connolly GM,Mill CEJ,Williams H,Angelini GD,Johnson JL,George SJ
Fri Feb 01 00:00:00 EST 2019
Role of CXCR2 in the Ac-PGP-Induced Mobilization of Circulating Angiogenic Cells and its Therapeutic Implications.
Stem cells translational medicine
Kwon YW,Lee SJ,Heo SC,Lee TW,Park GT,Yoon JW,Kim SC,Shin HJ,Lee SC,Kim JH
Fri Mar 01 00:00:00 EST 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Chemokines as the modulators of endometrial epithelial cells remodelling.
Scientific reports
Złotkowska A,Andronowska A
Tue Sep 10 00:00:00 EDT 2019
Role of lysophosphatidic acid in proliferation and differentiation of intestinal epithelial cells.
PloS one
Konno T,Kotani T,Setiawan J,Nishigaito Y,Sawada N,Imada S,Saito Y,Murata Y,Matozaki T
250-19 was used in Cell Culture to suggest that lysophosphatidic acid (LPA) is a key factor that drives the proliferation and differentiation of intestinal epithelial cells (IECs).
Wed Jan 29 00:00:00 EST 2020
Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.
Stem cell research & therapy
I T,Sumita Y,Yoshida T,Honma R,Iwatake M,Raudales JLM,Shizuno T,Kuroshima S,Masuda H,Seki M,Tran SD,Asahara T,Asahina I
250-19 was used in Cell Culture to investigate methods conditioning peripheral blood mononuclear cells to regenerate salivary gland following head and neck cancer treatment.
Thu Oct 17 00:00:00 EDT 2019
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
Thu Feb 08 00:00:00 EST 2018
Resistance training recovers attenuated APPL1 expression and improves insulin-induced Akt signal activation in skeletal muscle of type 2 diabetic rats.
American journal of physiology. Endocrinology and metabolism
Kido K,Ato S,Yokokawa T,Sato K,Fujita S
Fri Jun 01 00:00:00 EDT 2018
Enhancing all-in-one bioreactors by combining interstitial perfusion, electrical stimulation, on-line monitoring and testing within a single chamber for cardiac constructs.
Scientific reports
Visone R,Talò G,Lopa S,Rasponi M,Moretti M
Fri Nov 16 00:00:00 EST 2018
Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids.
Translational psychiatry
Srikanth P,Lagomarsino VN,Muratore CR,Ryu SC,He A,Taylor WM,Zhou C,Arellano M,Young-Pearse TL
Thu Apr 12 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.
Proceedings of the National Academy of Sciences of the United States of America
Gao X,Lee HY,Li W,Platt RJ,Barrasa MI,Ma Q,Elmes RR,Rosenfeld MG,Lodish HF
Tue Sep 19 00:00:00 EDT 2017
Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.
Scientific reports
Tajima K,Shirakawa J,Togashi Y,Yamazaki S,Okuyama T,Kyohara M,Konishi H,Terauchi Y
Fri Jun 23 00:00:00 EDT 2017
Osteogenic Factor Runx2 Marks a Subset of Leptin Receptor-Positive Cells that Sit Atop the Bone Marrow Stromal Cell Hierarchy.
Scientific reports
Yang M,Arai A,Udagawa N,Hiraga T,Lijuan Z,Ito S,Komori T,Moriishi T,Matsuo K,Shimoda K,Zahalka AH,Kobayashi Y,Takahashi N,Mizoguchi T
Mon Jul 10 00:00:00 EDT 2017
NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.
Nature
Karki R,Man SM,Malireddi RKS,Kesavardhana S,Zhu Q,Burton AR,Sharma BR,Qi X,Pelletier S,Vogel P,Rosenstiel P,Kanneganti TD
250-19 was used in In vitro experiments to explore a key role for NLRC3 in mediating protection against colorectal cancer.
Thu Dec 22 00:00:00 EST 2016
PI3-kinase mutation linked to insulin and growth factor resistance in vivo.
The Journal of clinical investigation
Winnay JN,Solheim MH,Dirice E,Sakaguchi M,Noh HL,Kang HJ,Takahashi H,Chudasama KK,Kim JK,Molven A,Kahn CR,Njølstad PR
Fri Apr 01 00:00:00 EDT 2016
Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors.
Molecular therapy. Nucleic acids
Koblas T,Leontovyc I,Loukotova S,Kosinova L,Saudek F
Tue May 17 00:00:00 EDT 2016
Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro.
Nature protocols
Chal J,Al Tanoury Z,Hestin M,Gobert B,Aivio S,Hick A,Cherrier T,Nesmith AP,Parker KK,Pourquié O
Sat Oct 01 00:00:00 EDT 2016
Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice.
Stem cell reports
Zhang P,Xing C,Rhodes SD,He Y,Deng K,Li Z,He F,Zhu C,Nguyen L,Zhou Y,Chen S,Mohammad KS,Guise TA,Abdel-Wahab O,Xu M,Wang QF,Yang FC
Tue Jun 14 00:00:00 EDT 2016
Differentiation of pluripotent stem cells to muscle fiber to model Duchenne muscular dystrophy.
Nature biotechnology
Chal J,Oginuma M,Al Tanoury Z,Gobert B,Sumara O,Hick A,Bousson F,Zidouni Y,Mursch C,Moncuquet P,Tassy O,Vincent S,Miyanari A,Bera A,Garnier JM,Guevara G,Hestin M,Kennedy L,Hayashi S,Drayton B,Cherrier T,Gayraud-Morel B,Gussoni E,Relaix F,Tajbakhsh S,Pourquié O
Tue Sep 01 00:00:00 EDT 2015
Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells.
Cancer research
Jang GB,Hong IS,Kim RJ,Lee SY,Park SJ,Lee ES,Park JH,Yun CH,Chung JU,Lee KJ,Lee HY,Nam JS
250-19 was used in Cell Culture to indicate that CWP232228 offers a candidate therapeutic agent for breast cancer that preferentially targets BCSC as well as bulk tumor cells.
Wed Apr 15 00:00:00 EDT 2015
Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells.
Molecular therapy. Methods & clinical development
Pestina TI,Hargrove PW,Zhao H,Mead PE,Smeltzer MP,Weiss MJ,Wilber A,Persons DA
Tue Dec 15 00:00:00 EST 2015
Py2T murine breast cancer cells, a versatile model of TGFβ-induced EMT in vitro and in vivo.
PloS one
Waldmeier L,Meyer-Schaller N,Diepenbruck M,Christofori G
Wed Apr 24 00:00:00 EDT 2013
Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells.
PloS one
Nsair A,Schenke-Layland K,Van Handel B,Evseenko D,Kahn M,Zhao P,Mendelis J,Heydarkhan S,Awaji O,Vottler M,Geist S,Chyu J,Gago-Lopez N,Crooks GM,Plath K,Goldhaber J,Mikkola HK,MacLellan WR
Tue Apr 02 00:00:00 EDT 2013
Serine phosphorylation of the insulin-like growth factor I (IGF-1) receptor C-terminal tail restrains kinase activity and cell growth.
The Journal of biological chemistry
Kelly GM,Buckley DA,Kiely PA,Adams DR,O'Connor R
Fri Aug 10 00:00:00 EDT 2012
SIRT1 deficiency compromises mouse embryonic stem cell hematopoietic differentiation, and embryonic and adult hematopoiesis in the mouse.
Blood
Ou X,Chae HD,Wang RH,Shelley WC,Cooper S,Taylor T,Kim YJ,Deng CX,Yoder MC,Broxmeyer HE
Thu Jan 13 00:00:00 EST 2011
Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus.
Blood
England SJ,McGrath KE,Frame JM,Palis J
Thu Mar 03 00:00:00 EST 2011
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.
Nature
Méndez-Ferrer S,Michurina TV,Ferraro F,Mazloom AR,Macarthur BD,Lira SA,Scadden DT,Ma'ayan A,Enikolopov GN,Frenette PS
Thu Aug 12 00:00:00 EDT 2010
Plzf regulates germline progenitor self-renewal by opposing mTORC1.
Cell
Hobbs RM,Seandel M,Falciatori I,Rafii S,Pandolfi PP
Fri Aug 06 00:00:00 EDT 2010
c-kitpos GATA-4 high rat cardiac stem cells foster adult cardiomyocyte survival through IGF-1 paracrine signalling.
PloS one
Kawaguchi N,Smith AJ,Waring CD,Hasan MK,Miyamoto S,Matsuoka R,Ellison GM
Mon Dec 13 00:00:00 EST 2010
Alendronate inhibits VEGF expression in growth plate chondrocytes by acting on the mevalonate pathway.
The open orthopaedics journal
Evans KD,Oberbauer AM
Thu Oct 01 00:00:00 EDT 2009
Enucleation of primitive erythroid cells generates a transient population of "pyrenocytes" in the mammalian fetus.
Blood
McGrath KE,Kingsley PD,Koniski AD,Porter RL,Bushnell TP,Palis J
Fri Feb 15 00:00:00 EST 2008
Lyn kinase promotes erythroblast expansion and late-stage development.
Blood
Karur VG,Lowell CA,Besmer P,Agosti V,Wojchowski DM
Fri Sep 01 00:00:00 EDT 2006
Coordination of erythropoiesis by the transcription factor c-Myb.
Blood
Vegiopoulos A,García P,Emambokus N,Frampton J
Thu Jun 15 00:00:00 EDT 2006
A role for thrombopoietin in hemangioblast development.
Stem cells (Dayton, Ohio)
Perlingeiro RC,Kyba M,Bodie S,Daley GQ
Fri Feb 27 00:00:00 EST 2004
