Product References
Outer Membrane Vesicle-Based Nanohybrids Target Tumor-Associated Macrophages to Enhance Trained Immunity-Related Vaccine-Generated Antitumor Activity.
Advanced materials (Deerfield Beach, Fla.)
Liang J,Zhu F,Cheng K,Ma N,Ma X,Feng Q,Xu C,Gao X,Wang X,Shi J,Zhao X,Nie G
AF-214-14 was used in In vitro experiments to develop and identifies OMV-based TIrV, but also investigates the trained immunity signatures and therapeutic mechanisms, providing a basis for further vaccination strategies.
Wed Nov 01 00:00:00 EDT 2023
Importance of Bcl-2-family proteins in murine hematopoietic progenitor and early B cells.
Cell death & disease
Kurschat C,Metz A,Kirschnek S,Häcker G
Wed Aug 11 00:00:00 EDT 2021
A smart multiantenna gene theranostic system based on the programmed assembly of hypoxia-related siRNAs.
Nature communications
Gong X,Wang H,Li R,Tan K,Wei J,Wang J,Hong C,Shang J,Liu X,Liu J,Wang F
Fri Jun 25 00:00:00 EDT 2021
Influenza virus infection expands the breadth of antibody responses through IL-4 signalling in B cells.
Nature communications
Miyauchi K,Adachi Y,Tonouchi K,Yajima T,Harada Y,Fukuyama H,Deno S,Iwakura Y,Yoshimura A,Hasegawa H,Yugi K,Fujii SI,Ohara O,Takahashi Y,Kubo M
Fri Jun 18 00:00:00 EDT 2021
Personalized cancer vaccine strategy elicits polyfunctional T cells and demonstrates clinical benefits in ovarian cancer.
NPJ vaccines
Tanyi JL,Chiang CL,Chiffelle J,Thierry AC,Baumgartener P,Huber F,Goepfert C,Tarussio D,Tissot S,Torigian DA,Nisenbaum HL,Stevenson BJ,Guiren HF,Ahmed R,Huguenin-Bergenat AL,Zsiros E,Bassani-Sternberg M,Mick R,Powell DJ,Coukos G,Harari A,Kandalaft LE
Mon Mar 15 00:00:00 EDT 2021
Ceramides and sphingosine-1-phosphate mediate the distinct effects of M1/M2-macrophage infusion on liver recovery after hepatectomy.
Cell death & disease
Sun H,Sun S,Chen G,Xie H,Yu S,Lin X,Qian J,Mao C,Peng H,Chen H,Chen X,Li Y,Liu C,Shi J,Zhu B,Guo L,Li Q,Huang P,Wei Y,Huang X,Liu M,Cui Z,Zhang Q,Zhou J,Li C,Wang K
Fri Mar 26 00:00:00 EDT 2021
Repurposing the anthelmintic praziquantel to treat psoriasis.
British journal of pharmacology
Hao L,Mao Y,Park J,Bae EJ,Park BH
AF-214-14 was used in Cell Culture to provide the first preclinical evidence that praziquantel may effectively treat psoriasis, and suggest that praziquantel alleviates symptoms in mice by inhibiting STAT3 phosphorylation, thereby suppressing Th17 immune responses.
Wed Dec 01 00:00:00 EST 2021
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia.
Nature communications
Consonni M,Garavaglia C,Grilli A,de Lalla C,Mancino A,Mori L,De Libero G,Montagna D,Casucci M,Serafini M,Bonini C,Häussinger D,Ciceri F,Bernardi M,Mastaglio S,Bicciato S,Dellabona P,Casorati G
Wed Aug 11 00:00:00 EDT 2021
Differences in in vitro microglial accumulation of the energy metabolism tracers [18F]FDG and [18F]BCPP-EF during LPS- and IL4 stimulation.
Scientific reports
Suzuki C,Han S,Kesavamoorthy G,Kosugi M,Araki K,Harada N,Kanazawa M,Tsukada H,Magata Y,Ouchi Y
Thu Jun 24 00:00:00 EDT 2021
IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation.
Cell death & disease
Cui J,Xu H,Yu J,Li Y,Chen Z,Zou Y,Zhang X,Du Y,Xia J,Wu J
Tue May 18 00:00:00 EDT 2021
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
Nature metabolism
Bidault G,Virtue S,Petkevicius K,Jolin HE,Dugourd A,Guénantin AC,Leggat J,Mahler-Araujo B,Lam BYH,Ma MK,Dale M,Carobbio S,Kaser A,Fallon PG,Saez-Rodriguez J,McKenzie ANJ,Vidal-Puig A
Wed Sep 01 00:00:00 EDT 2021
SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation.
Nature metabolism
Bidault G,Virtue S,Petkevicius K,Jolin HE,Dugourd A,Guénantin AC,Leggat J,Mahler-Araujo B,Lam BYH,Ma MK,Dale M,Carobbio S,Kaser A,Fallon PG,Saez-Rodriguez J,McKenzie ANJ,Vidal-Puig A
Wed Sep 01 00:00:00 EDT 2021
NR1D1 modulates synovial inflammation and bone destruction in rheumatoid arthritis.
Cell death & disease
Liu H,Zhu Y,Gao Y,Qi D,Zhao L,Zhao L,Liu C,Tao T,Zhou C,Sun X,Guo F,Xiao J
Tue Feb 18 00:00:00 EST 2020
Intervention of oncostatin M-driven mucosal inflammation by berberine exerts therapeutic property in chronic ulcerative colitis.
Cell death & disease
Li H,Feng C,Fan C,Yang Y,Yang X,Lu H,Lu Q,Zhu F,Xiang C,Zhang Z,He P,Zuo J,Tang W
Fri Apr 24 00:00:00 EDT 2020
Nfkbie-deficiency leads to increased susceptibility to develop B-cell lymphoproliferative disorders in aged mice.
Blood cancer journal
Della-Valle V,Roos-Weil D,Scourzic L,Mouly E,Aid Z,Darwiche W,Lecluse Y,Damm F,Mémet S,Mercher T,Aoufouchi S,Nguyen-Khac F,Bernard OA,Ghamlouch H
Fri Mar 13 00:00:00 EDT 2020
Silencing lncRNA Lfar1 alleviates the classical activation and pyoptosis of macrophage in hepatic fibrosis.
Cell death & disease
Zhang K,Shi Z,Zhang M,Dong X,Zheng L,Li G,Han X,Yao Z,Han T,Hong W
Tue Feb 18 00:00:00 EST 2020
CD4+ T-Cell Differentiation In Vitro.
Methods in molecular biology (Clifton, N.J.)
Yang W,Chen X,Hu H
AF-214-14 was used in In vitro experiments to study the regulating mechanism and function of Th cells, dependent on in vitro CD4+ T-cell differentiation.
Tue Jan 26 00:00:00 EST 2021
An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses.
Nature communications
Wang G,Kang X,Chen KS,Jehng T,Jones L,Chen J,Huang XF,Chen SY
Fri Mar 13 00:00:00 EDT 2020
In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells.
Nature communications
Luthria G,Li R,Wang S,Prytyskach M,Kohler RH,Lauffenburger DA,Mitchison TJ,Weissleder R,Miller MA
Tue Jul 14 00:00:00 EDT 2020
Bacterial polyphosphates interfere with the innate host defense to infection.
Nature communications
Roewe J,Stavrides G,Strueve M,Sharma A,Marini F,Mann A,Smith SA,Kaya Z,Strobl B,Mueller M,Reinhardt C,Morrissey JH,Bosmann M
Wed Aug 12 00:00:00 EDT 2020
TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis.
Viruses
Mandal P,McCormick AL,Mocarski ES
AF-214-14 was used in Cell Culture to conclude that caspase-8 suppression by vICA emerges as key to subverting innate immune elimination of a wide variety of infected cell types.
Wed Oct 28 00:00:00 EDT 2020
Reactive oxygen species modulate macrophage immunosuppressive phenotype through the up-regulation of PD-L1.
Proceedings of the National Academy of Sciences of the United States of America
Roux C,Jafari SM,Shinde R,Duncan G,Cescon DW,Silvester J,Chu MF,Hodgson K,Berger T,Wakeham A,Palomero L,Garcia-Valero M,Pujana MA,Mak TW,McGaha TL,Cappello P,Gorrini C
Tue Mar 05 00:00:00 EST 2019
Potential of recombinant Mycobacterium paragordonae expressing HIV-1 Gag as a prime vaccine for HIV-1 infection.
Scientific reports
Kim BJ,Kim BR,Kook YH,Kim BJ
Tue Oct 29 00:00:00 EDT 2019
Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells.
Cell reports
Myers DR,Norlin E,Vercoulen Y,Roose JP
AF-214-14 was used in Cell Culture to investigate the role of Rasgrp1 in selective and robust tonic mTORC1 signals in CD4+ T cells.
Tue May 07 00:00:00 EDT 2019
RIG-I-like receptors direct inflammatory macrophage polarization against West Nile virus infection.
Nature communications
Stone AEL,Green R,Wilkins C,Hemann EA,Gale M
Tue Aug 13 00:00:00 EDT 2019
Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock.
Immunity
Mandal P,Feng Y,Lyons JD,Berger SB,Otani S,DeLaney A,Tharp GK,Maner-Smith K,Burd EM,Schaeffer M,Hoffman S,Capriotti C,Roback L,Young CB,Liang Z,Ortlund EA,DiPaolo NC,Bosinger S,Bertin J,Gough PJ,Brodsky IE,Coopersmith CM,Shayakhmetov DM,Mocarski ES
Tue Jul 17 00:00:00 EDT 2018
The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes.
The EMBO journal
Fletcher K,Ulferts R,Jacquin E,Veith T,Gammoh N,Arasteh JM,Mayer U,Carding SR,Wileman T,Beale R,Florey O
AF-214-14 was used in Cell Culture to demonstrate activation of non-canonical autophagy dependent on the WD40 CTD during influenza A virus infection.
Thu Feb 15 00:00:00 EST 2018
M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis.
Cell communication and signaling : CCS
Hou J,Shi J,Chen L,Lv Z,Chen X,Cao H,Xiang Z,Han X
AF-214-14 was used in Cell Culture to study the interaction between lung resident mesenchymal stem cells (LR-MSCs) and macrophages using a bleomycin-induced mouse pulmonary fibrosis model and a coculture system.
Fri Nov 23 00:00:00 EST 2018
RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.
EMBO molecular medicine
Zhu H,Lou F,Yin Q,Gao Y,Sun Y,Bai J,Xu Z,Liu Z,Cai W,Ke F,Zhang L,Zhou H,Wang H,Wang G,Chen X,Zhang H,Wang Z,Ginhoux F,Lu C,Su B,Wang H
Mon May 01 00:00:00 EDT 2017
Local proliferation initiates macrophage accumulation in adipose tissue during obesity.
Cell death & disease
Zheng C,Yang Q,Cao J,Xie N,Liu K,Shou P,Qian F,Wang Y,Shi Y
Thu Mar 31 00:00:00 EDT 2016
Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development.
Immunity, inflammation and disease
Braga TT,Correa-Costa M,Azevedo H,Silva RC,Cruz MC,Almeida ME,Hiyane MI,Moreira-Filho CA,Santos MF,Perez KR,Cuccovia IM,Camara NO
Thu Sep 01 00:00:00 EDT 2016
Higher Sensitivity of Foxp3+ Treg Compared to Foxp3- Conventional T Cells to TCR-Independent Signals for CD69 Induction.
PloS one
Bremser A,Brack M,Izcue A
AF-214-14 was used in Cell Culture to investigate the effects of TCR signals on T cells through studying the expression of T cell activation marker CD69.
Tue May 24 00:00:00 EDT 2016
Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization.
Cellular & molecular immunology
Lin Y,Yang X,Yue W,Xu X,Li B,Zou L,He R
Tue Jul 01 00:00:00 EDT 2014
The inhibitory effect of IFN-γ on protease HTRA1 expression in rheumatoid arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Hou Y,Lin H,Zhu L,Liu Z,Hu F,Shi J,Yang T,Shi X,Guo H,Tan X,Zhang L,Wang Q,Li Z,Zhao Y
Tue Jul 01 00:00:00 EDT 2014
Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.
Immunity
Spence S,Fitzsimons A,Boyd CR,Kessler J,Fitzgerald D,Elliott J,Gabhann JN,Smith S,Sica A,Hams E,Saunders SP,Jefferies CA,Fallon PG,McAuley DF,Kissenpfennig A,Johnston JA
Thu Jan 24 00:00:00 EST 2013
Differential effects of γc cytokines on postselection differentiation of CD8 thymocytes.
Blood
Rafei M,Rouette A,Brochu S,Vanegas JR,Perreault C
Thu Jan 03 00:00:00 EST 2013
Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences.
Blood
Martinez FO,Helming L,Milde R,Varin A,Melgert BN,Draijer C,Thomas B,Fabbri M,Crawshaw A,Ho LP,Ten Hacken NH,Cobos Jiménez V,Kootstra NA,Hamann J,Greaves DR,Locati M,Mantovani A,Gordon S
Thu Feb 28 00:00:00 EST 2013
Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes.
Proceedings of the National Academy of Sciences of the United States of America
Swee LK,Guimaraes CP,Sehrawat S,Spooner E,Barrasa MI,Ploegh HL
Tue Jan 22 00:00:00 EST 2013
Thymic stromal lymphopoietin amplifies the differentiation of alternatively activated macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Han H,Headley MB,Xu W,Comeau MR,Zhou B,Ziegler SF
Fri Feb 01 00:00:00 EST 2013
An HLA-DRB1-coded signal transduction ligand facilitates inflammatory arthritis: a new mechanism of autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Holoshitz J,Liu Y,Fu J,Joseph J,Ling S,Colletta A,Sharma P,Begun D,Goldstein S,Taichman R
Tue Jan 01 00:00:00 EST 2013
Glioma stem cell-targeted dendritic cells as a tumor vaccine against malignant glioma.
Yonsei medical journal
Ji B,Chen Q,Liu B,Wu L,Tian D,Guo Z,Yi W
Tue Jan 01 00:00:00 EST 2013
Toll-like receptor 4 engagement drives differentiation of human and murine dendritic cells from a pro- into an anti-inflammatory mode.
PloS one
Luger R,Valookaran S,Knapp N,Vizzardelli C,Dohnal AM,Felzmann T
Fri Sep 06 00:00:00 EDT 2013
The 3' enhancer CNS2 is a critical regulator of interleukin-4-mediated humoral immunity in follicular helper T cells.
Immunity
Harada Y,Tanaka S,Motomura Y,Harada Y,Ohno S,Ohno S,Yanagi Y,Inoue H,Kubo M
Fri Feb 24 00:00:00 EST 2012
Regulatory dendritic cells program B cells to differentiate into CD19hiFcγIIbhi regulatory B cells through IFN-β and CD40L.
Blood
Qian L,Qian C,Chen Y,Bai Y,Bao Y,Lu L,Cao X
Thu Jul 19 00:00:00 EDT 2012
Induction of IL-4Rα-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo.
Blood
Rückerl D,Jenkins SJ,Laqtom NN,Gallagher IJ,Sutherland TE,Duncan S,Buck AH,Allen JE
Thu Sep 13 00:00:00 EDT 2012
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.
Blood
Pello OM,De Pizzol M,Mirolo M,Soucek L,Zammataro L,Amabile A,Doni A,Nebuloni M,Swigart LB,Evan GI,Mantovani A,Locati M
Thu Jan 12 00:00:00 EST 2012
Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice.
Blood
Ottina E,Grespi F,Tischner D,Soratroi C,Geley S,Ploner A,Reichardt HM,Villunger A,Herold MJ
Thu Jun 21 00:00:00 EDT 2012
TNF signaling drives myeloid-derived suppressor cell accumulation.
The Journal of clinical investigation
Zhao X,Rong L,Zhao X,Li X,Liu X,Deng J,Wu H,Xu X,Erben U,Wu P,Syrbe U,Sieper J,Qin Z
Thu Nov 01 00:00:00 EDT 2012
Periostin promotes chronic allergic inflammation in response to Th2 cytokines.
The Journal of clinical investigation
Masuoka M,Shiraishi H,Ohta S,Suzuki S,Arima K,Aoki S,Toda S,Inagaki N,Kurihara Y,Hayashida S,Takeuchi S,Koike K,Ono J,Noshiro H,Furue M,Conway SJ,Narisawa Y,Izuhara K
Sun Jul 01 00:00:00 EDT 2012
Viral acute lower respiratory infections impair CD8+ T cells through PD-1.
The Journal of clinical investigation
Erickson JJ,Gilchuk P,Hastings AK,Tollefson SJ,Johnson M,Downing MB,Boyd KL,Johnson JE,Kim AS,Joyce S,Williams JV
Wed Aug 01 00:00:00 EDT 2012
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.
The Journal of clinical investigation
Brüstle A,Brenner D,Knobbe CB,Lang PA,Virtanen C,Hershenfield BM,Reardon C,Lacher SM,Ruland J,Ohashi PS,Mak TW
Sat Dec 01 00:00:00 EST 2012
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.
The Journal of experimental medicine
Hao Z,Duncan GS,Su YW,Li WY,Silvester J,Hong C,You H,Brenner D,Gorrini C,Haight J,Wakeham A,You-Ten A,McCracken S,Elia A,Li Q,Detmar J,Jurisicova A,Hobeika E,Reth M,Sheng Y,Lang PA,Ohashi PS,Zhong Q,Wang X,Mak TW
Mon Jan 16 00:00:00 EST 2012
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.
The Journal of experimental medicine
Satpathy AT,KC W,Albring JC,Edelson BT,Kretzer NM,Bhattacharya D,Murphy TL,Murphy KM
Mon Jun 04 00:00:00 EDT 2012
UNG shapes the specificity of AID-induced somatic hypermutation.
The Journal of experimental medicine
Pérez-Durán P,Belver L,de Yébenes VG,Delgado P,Pisano DG,Ramiro AR
Mon Jul 02 00:00:00 EDT 2012
High-mobility group nucleosome-binding protein 1 acts as an alarmin and is critical for lipopolysaccharide-induced immune responses.
The Journal of experimental medicine
Yang D,Postnikov YV,Li Y,Tewary P,de la Rosa G,Wei F,Klinman D,Gioannini T,Weiss JP,Furusawa T,Bustin M,Oppenheim JJ
Mon Jan 16 00:00:00 EST 2012
Coreceptor gene imprinting governs thymocyte lineage fate.
The EMBO journal
Adoro S,McCaughtry T,Erman B,Alag A,Van Laethem F,Park JH,Tai X,Kimura M,Wang L,Grinberg A,Kubo M,Bosselut R,Love P,Singer A
Wed Jan 18 00:00:00 EST 2012
Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages.
Proceedings of the National Academy of Sciences of the United States of America
Clark K,MacKenzie KF,Petkevicius K,Kristariyanto Y,Zhang J,Choi HG,Peggie M,Plater L,Pedrioli PG,McIver E,Gray NS,Arthur JS,Cohen P
Tue Oct 16 00:00:00 EDT 2012
Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) and elongation factor, RNA polymerase II, 2 (ELL2) are regulators of mRNA processing in plasma cells.
Proceedings of the National Academy of Sciences of the United States of America
Benson MJ,Aijö T,Chang X,Gagnon J,Pape UJ,Anantharaman V,Aravind L,Pursiheimo JP,Oberdoerffer S,Liu XS,Lahesmaa R,Lähdesmäki H,Rao A
Tue Oct 02 00:00:00 EDT 2012
Quantification of lymph node transit times reveals differences in antigen surveillance strategies of naive CD4+ and CD8+ T cells.
Proceedings of the National Academy of Sciences of the United States of America
Mandl JN,Liou R,Klauschen F,Vrisekoop N,Monteiro JP,Yates AJ,Huang AY,Germain RN
Tue Oct 30 00:00:00 EDT 2012
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.
PLoS pathogens
Broadhurst MJ,Leung JM,Lim KC,Girgis NM,Gundra UM,Fallon PG,Premenko-Lanier M,McKerrow JH,McCune JM,Loke P
Mon Dec 17 00:00:00 EST 2012
Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice.
PLoS pathogens
Broadhurst MJ,Leung JM,Lim KC,Girgis NM,Gundra UM,Fallon PG,Premenko-Lanier M,McKerrow JH,McCune JM,Loke P
Mon Dec 17 00:00:00 EST 2012
Effects of interferon-α-transduced tumor cell vaccines and blockade of programmed cell death-1 on the growth of established tumors.
Cancer gene therapy
Omori R,Eguchi J,Hiroishi K,Ishii S,Hiraide A,Sakaki M,Doi H,Kajiwara A,Ito T,Kogo M,Imawari M
Sat Sep 01 00:00:00 EDT 2012
Autoreactive preplasma cells break tolerance in the absence of regulation by dendritic cells and macrophages.
Journal of immunology (Baltimore, Md. : 1950)
Gilbert MR,Wagner NJ,Jones SZ,Wisz AB,Roques JR,Krum KN,Lee SR,Nickeleit V,Hulbert C,Thomas JW,Gauld SB,Vilen BJ
Sun Jul 15 00:00:00 EDT 2012
Negative feedback regulation of antigen receptors through calmodulin inhibition of E2A.
Journal of immunology (Baltimore, Md. : 1950)
Verma-Gaur J,Hauser J,Grundström T
Fri Jun 15 00:00:00 EDT 2012
RGS16 attenuates pulmonary Th2/Th17 inflammatory responses.
Journal of immunology (Baltimore, Md. : 1950)
Shankar SP,Wilson MS,DiVietro JA,Mentink-Kane MM,Xie Z,Wynn TA,Druey KM
Fri Jun 15 00:00:00 EDT 2012
Dectin-1 stimulation induces suppressor of cytokine signaling 1, thereby modulating TLR signaling and T cell responses.
Journal of immunology (Baltimore, Md. : 1950)
Eberle ME,Dalpke AH
Fri Jun 01 00:00:00 EDT 2012
Regulation of the inflammatory response: enhancing neutrophil infiltration under chronic inflammatory conditions.
Journal of immunology (Baltimore, Md. : 1950)
Bian Z,Guo Y,Ha B,Zen K,Liu Y
Sun Jan 15 00:00:00 EST 2012
Dendritic cell-specific disruption of TGF-β receptor II leads to altered regulatory T cell phenotype and spontaneous multiorgan autoimmunity.
Journal of immunology (Baltimore, Md. : 1950)
Ramalingam R,Larmonier CB,Thurston RD,Midura-Kiela MT,Zheng SG,Ghishan FK,Kiela PR
Mon Oct 15 00:00:00 EDT 2012
Splenic stroma-educated regulatory dendritic cells induce apoptosis of activated CD4 T cells via Fas ligand-enhanced IFN-γ and nitric oxide.
Journal of immunology (Baltimore, Md. : 1950)
Xu X,Yi H,Guo Z,Qian C,Xia S,Yao Y,Cao X
Wed Feb 01 00:00:00 EST 2012
SAP is required for the development of innate phenotype in H2-M3--restricted Cd8(+) T cells.
Journal of immunology (Baltimore, Md. : 1950)
Bediako Y,Bian Y,Zhang H,Cho H,Stein PL,Wang CR
Thu Nov 15 00:00:00 EST 2012
STAT6-dependent regulation of Th9 development.
Journal of immunology (Baltimore, Md. : 1950)
Goswami R,Jabeen R,Yagi R,Pham D,Zhu J,Goenka S,Kaplan MH
Wed Feb 01 00:00:00 EST 2012
Cutting edge: histamine is required for IL-4-driven eosinophilic allergic responses.
Journal of immunology (Baltimore, Md. : 1950)
Swartzendruber JA,Byrne AJ,Bryce PJ
Sun Jan 15 00:00:00 EST 2012
Negative regulation of NKG2D expression by IL-4 in memory CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Ventre E,Brinza L,Schicklin S,Mafille J,Coupet CA,Marçais A,Djebali S,Jubin V,Walzer T,Marvel J
Mon Oct 01 00:00:00 EDT 2012
Twist1 regulates Ifng expression in Th1 cells by interfering with Runx3 function.
Journal of immunology (Baltimore, Md. : 1950)
Pham D,Vincentz JW,Firulli AB,Kaplan MH
Sun Jul 15 00:00:00 EDT 2012
Comparative and functional evaluation of in vitro generated to ex vivo CD8 T cells.
Journal of immunology (Baltimore, Md. : 1950)
Dervovic DD,Ciofani M,Kianizad K,Zúñiga-Pflücker JC
Mon Oct 01 00:00:00 EDT 2012
Dihydroartemisinin ameliorates inflammatory disease by its reciprocal effects on Th and regulatory T cell function via modulating the mammalian target of rapamycin pathway.
Journal of immunology (Baltimore, Md. : 1950)
Zhao YG,Wang Y,Guo Z,Gu AD,Dan HC,Baldwin AS,Hao W,Wan YY
Thu Nov 01 00:00:00 EDT 2012
Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.
Journal of immunology (Baltimore, Md. : 1950)
Hasham MG,Snow KJ,Donghia NM,Branca JA,Lessard MD,Stavnezer J,Shopland LS,Mills KD
Sat Sep 01 00:00:00 EDT 2012
Lipopolysaccharide-activated dendritic cells: "exhausted" or alert and waiting?
Journal of immunology (Baltimore, Md. : 1950)
Abdi K,Singh NJ,Matzinger P
Fri Jun 15 00:00:00 EDT 2012
Cutting edge: microRNA regulation of macrophage fusion into multinucleated giant cells.
Journal of immunology (Baltimore, Md. : 1950)
Sissons JR,Peschon JJ,Schmitz F,Suen R,Gilchrist M,Aderem A
Sun Jul 01 00:00:00 EDT 2012
Gcn5 is required for PU.1-dependent IL-9 induction in Th9 cells.
Journal of immunology (Baltimore, Md. : 1950)
Goswami R,Kaplan MH
Sat Sep 15 00:00:00 EDT 2012
Dynamics of the splenic innate-like CD19⁺CD45Rlo cell population from adult mice in homeostatic and activated conditions.
Journal of immunology (Baltimore, Md. : 1950)
de Andrés B,Prado C,Palacios B,Alía M,Jagtap S,Serrano N,Cortegano I,Marcos MA,Gaspar ML
Sat Sep 01 00:00:00 EDT 2012
Augmented IL-15Rα expression by CD40 activation is critical in synergistic CD8 T cell-mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice.
Journal of immunology (Baltimore, Md. : 1950)
Zhang M,Ju W,Yao Z,Yu P,Wei BR,Simpson RM,Waitz R,Fassò M,Allison JP,Waldmann TA
Fri Jun 15 00:00:00 EDT 2012
Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing.
Journal of immunology (Baltimore, Md. : 1950)
Shen S,Manser T
Sun Jan 01 00:00:00 EST 2012
Crucial role of granulocytic myeloid-derived suppressor cells in the regulation of central nervous system autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950)
Ioannou M,Alissafi T,Lazaridis I,Deraos G,Matsoukas J,Gravanis A,Mastorodemos V,Plaitakis A,Sharpe A,Boumpas D,Verginis P
Wed Feb 01 00:00:00 EST 2012
Fyn promotes Th17 differentiation by regulating the kinetics of RORγt and Foxp3 expression.
Journal of immunology (Baltimore, Md. : 1950)
Ueda A,Zhou L,Stein PL
Fri Jun 01 00:00:00 EDT 2012
Metabolic characterization of Leishmania major infection in activated and nonactivated macrophages.
Journal of proteome research
Lamour SD,Choi BS,Keun HC,Müller I,Saric J
Fri Aug 03 00:00:00 EDT 2012
Inchingorei-san (TJ-117) and Artemisiae Capillaris Herba Induced Prolonged Survival of Fully Mismatched Cardiac Allografts and Generated Regulatory Cells in Mice.
Evidence-based complementary and alternative medicine : eCAM
Jin X,Uchiyama M,Zhang Q,Hirai T,Niimi M
Thu Aug 23 00:00:00 EDT 2012
TGFβ signaling plays a critical role in promoting alternative macrophage activation.
BMC immunology
Gong D,Shi W,Yi SJ,Chen H,Groffen J,Heisterkamp N
Fri Jun 15 00:00:00 EDT 2012
Environmental conditioning in the control of macrophage thrombospondin-1 production.
Scientific reports
Fordham JB,Hua J,Morwood SR,Schewitz-Bowers LP,Copland DA,Dick AD,Nicholson LB
Sun Mar 17 00:00:00 EDT 2013
The E3 ubiquitin ligase neuregulin receptor degradation protein 1 (Nrdp1) promotes M2 macrophage polarization by ubiquitinating and activating transcription factor CCAAT/enhancer-binding Protein β (C/EBPβ).
The Journal of biological chemistry
Ye S,Xu H,Jin J,Yang M,Wang C,Yu Y,Cao X
Fri Aug 03 00:00:00 EDT 2012
Neisseria gonorrhoeae suppresses dendritic cell-induced, antigen-dependent CD4 T cell proliferation.
PloS one
Zhu W,Ventevogel MS,Knilans KJ,Anderson JE,Oldach LM,McKinnon KP,Hobbs MM,Sempowski GD,Duncan JA
Wed Nov 28 00:00:00 EST 2012
Estrogen represses hepatocellular carcinoma (HCC) growth via inhibiting alternative activation of tumor-associated macrophages (TAMs).
The Journal of biological chemistry
Yang W,Lu Y,Xu Y,Xu L,Zheng W,Wu Y,Li L,Shen P
Fri Nov 23 00:00:00 EST 2012
Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model.
PloS one
Li X,Li JJ,Yang JY,Wang DS,Zhao W,Song WJ,Li WM,Wang JF,Han W,Zhang ZC,Yu Y,Cao DY,Dou KF
Thu Feb 07 00:00:00 EST 2013
p38α protein negatively regulates T helper type 2 responses by orchestrating multiple T cell receptor-associated signals.
The Journal of biological chemistry
Hu P,Nebreda AR,Liu Y,Carlesso N,Kaplan M,Kapur R
Fri Sep 28 00:00:00 EDT 2012
Functional identification of dendritic cells in the teleost model, rainbow trout (Oncorhynchus mykiss).
PloS one
Bassity E,Clark TG
Mon Aug 20 00:00:00 EDT 2012
Role of the tumor suppressor ARF in macrophage polarization: Enhancement of the M2 phenotype in ARF-deficient mice.
Oncoimmunology
Herranz S,Través PG,Luque A,Hortelano S
Thu Nov 01 00:00:00 EDT 2012
Up-regulation of GITRL on dendritic cells by WGP improves anti-tumor immunity in murine Lewis lung carcinoma.
PloS one
Tian J,Ma J,Ma K,Ma B,Tang X,Baidoo SE,Tong J,Yan J,Lu L,Xu H,Wang S
Thu Mar 28 00:00:00 EDT 2013
Chronic infection drives expression of the inhibitory receptor CD200R, and its ligand CD200, by mouse and human CD4 T cells.
PloS one
Caserta S,Nausch N,Sawtell A,Drummond R,Barr T,Macdonald AS,Mutapi F,Zamoyska R
Thu Aug 23 00:00:00 EDT 2012
Adoptive transfer of Th1-conditioned lymphocytes promotes axonal remodeling and functional recovery after spinal cord injury.
Cell death & disease
Ishii H,Jin X,Ueno M,Tanabe S,Kubo T,Serada S,Naka T,Yamashita T
Thu Aug 09 00:00:00 EDT 2012
Topographical and biological evidence revealed FTY720-mediated anergy-polarization of mouse bone marrow-derived dendritic cells in vitro.
PloS one
Zeng X,Wang T,Zhu C,Xing X,Ye Y,Lai X,Song B,Zeng Y
Mon Oct 22 00:00:00 EDT 2012
FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatment.
PloS one
Saluja R,Delin I,Nilsson GP,Adner M
Wed Jan 16 00:00:00 EST 2013
Dual anti-OX40/IL-2 therapy augments tumor immunotherapy via IL-2R-mediated regulation of OX40 expression.
PloS one
Redmond WL,Triplett T,Floyd K,Weinberg AD
Tue Aug 21 00:00:00 EDT 2012
Multiwalled carbon nanotubes interact with macrophages and influence tumor progression and metastasis.
Theranostics
Yang M,Meng J,Cheng X,Lei J,Guo H,Zhang W,Kong H,Xu H
Tue Oct 02 00:00:00 EDT 2012
Simian immunodeficiency virus-Vpx for improving integrase defective lentiviral vector-based vaccines.
Retrovirology
Negri DR,Rossi A,Blasi M,Michelini Z,Leone P,Chiantore MV,Baroncelli S,Perretta G,Cimarelli A,Klotman ME,Cara A
Wed Aug 22 00:00:00 EDT 2012
Paracrine and transpresentation functions of IL-15 are mediated by diverse splice versions of IL-15Rα in human monocytes and dendritic cells.
The Journal of biological chemistry
Müller JR,Waldmann TA,Kruhlak MJ,Dubois S
Fri Nov 23 00:00:00 EST 2012
Gene silencing of IL-12 in dendritic cells inhibits autoimmune arthritis.
Journal of translational medicine
Li R,Zheng X,Popov I,Zhang X,Wang H,Suzuki M,Necochea-Campion RD,French PW,Chen D,Siu L,Koos D,Inman RD,Min WP
Tue Jan 31 00:00:00 EST 2012
Exposure of a distinct PDCA-1+ (CD317) B cell population to agonistic anti-4-1BB (CD137) inhibits T and B cell responses both in vitro and in vivo.
PloS one
Vinay DS,Lee SJ,Kim CH,Oh HS,Kwon BS
Mon May 13 00:00:00 EDT 2013
Auditory stimulation of opera music induced prolongation of murine cardiac allograft survival and maintained generation of regulatory CD4+CD25+ cells.
Journal of cardiothoracic surgery
Uchiyama M,Jin X,Zhang Q,Hirai T,Amano A,Bashuda H,Niimi M
Fri Mar 23 00:00:00 EDT 2012
De novo DNA methylation is required to restrict T helper lineage plasticity.
The Journal of biological chemistry
Thomas RM,Gamper CJ,Ladle BH,Powell JD,Wells AD
Fri Jun 29 00:00:00 EDT 2012
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Blood
Cudejko C,Wouters K,Fuentes L,Hannou SA,Paquet C,Bantubungi K,Bouchaert E,Vanhoutte J,Fleury S,Remy P,Tailleux A,Chinetti-Gbaguidi G,Dombrowicz D,Staels B,Paumelle R
Thu Sep 01 00:00:00 EDT 2011
Emergency granulopoiesis promotes neutrophil-dendritic cell encounters that prevent mouse lung allograft acceptance.
Blood
Kreisel D,Sugimoto S,Zhu J,Nava R,Li W,Okazaki M,Yamamoto S,Ibrahim M,Huang HJ,Toth KA,Ritter JH,Krupnick AS,Miller MJ,Gelman AE
Thu Dec 01 00:00:00 EST 2011
Transcriptomic analyses of murine resolution-phase macrophages.
Blood
Stables MJ,Shah S,Camon EB,Lovering RC,Newson J,Bystrom J,Farrow S,Gilroy DW
Thu Dec 22 00:00:00 EST 2011
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin.
Journal of biomedical science
Wei WC,Lin SY,Chen YJ,Wen CC,Huang CY,Palanisamy A,Yang NS,Sheu JH
Wed Dec 21 00:00:00 EST 2011
Retinal self-antigen induces a predominantly Th1 effector response in Axl and Mertk double-knockout mice.
Journal of immunology (Baltimore, Md. : 1950)
Ye F,Han L,Lu Q,Dong W,Chen Z,Shao H,Kaplan HJ,Li Q,Lu Q
Sat Oct 15 00:00:00 EDT 2011
Invariant NKT cell defects in vitamin D receptor knockout mice prevents experimental lung inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Yu S,Zhao J,Cantorna MT
Tue Nov 01 00:00:00 EDT 2011
Elf3 regulates allergic airway inflammation by controlling dendritic cell-driven T cell differentiation.
Journal of immunology (Baltimore, Md. : 1950)
Kushwah R,Oliver JR,Wu J,Chang Z,Hu J
Tue Nov 01 00:00:00 EDT 2011
Sensitivity and resistance to regulation by IL-4 during Th17 maturation.
Journal of immunology (Baltimore, Md. : 1950)
Cooney LA,Towery K,Endres J,Fox DA
Tue Nov 01 00:00:00 EDT 2011
Pyridone 6, a pan-JAK inhibitor, ameliorates allergic skin inflammation of NC/Nga mice via suppression of Th2 and enhancement of Th17.
Journal of immunology (Baltimore, Md. : 1950)
Nakagawa R,Yoshida H,Asakawa M,Tamiya T,Inoue N,Morita R,Inoue H,Nakao A,Yoshimura A
Tue Nov 01 00:00:00 EDT 2011
A p53 defect sensitizes various stages of B cell development to lymphomagenesis in mice carrying an IgH 3' regulatory region-driven c-myc transgene.
Journal of immunology (Baltimore, Md. : 1950)
Fiancette R,Rouaud P,Vincent-Fabert C,Laffleur B,Magnone V,Cogné M,Denizot Y
Thu Dec 01 00:00:00 EST 2011
Thymic stromal lymphopoietin is produced by dendritic cells.
Journal of immunology (Baltimore, Md. : 1950)
Kashyap M,Rochman Y,Spolski R,Samsel L,Leonard WJ
Mon Aug 01 00:00:00 EDT 2011
Cytokine-dependent and cytokine-independent roles for Mcl-1: genetic evidence for multiple mechanisms by which Mcl-1 promotes survival in primary T lymphocytes.
Cell death & disease
Dunkle A,Dzhagalov I,He YW
Thu Oct 06 00:00:00 EDT 2011
Overexpression of a minimal domain of calpastatin suppresses IL-6 production and Th17 development via reduced NF-κB and increased STAT5 signals.
PloS one
Iguchi-Hashimoto M,Usui T,Yoshifuji H,Shimizu M,Kobayashi S,Ito Y,Murakami K,Shiomi A,Yukawa N,Kawabata D,Nojima T,Ohmura K,Fujii T,Mimori T
Mon Mar 26 00:00:00 EDT 2012
Mice with different susceptibility to Japanese encephalitis virus infection show selective neutralizing antibody response and myeloid cell infectivity.
PloS one
Wang K,Deubel V
Mon Jan 30 00:00:00 EST 2012
