Gibco

Mouse LIX (CXCL6) (92 aa) Recombinant Protein, PeproTech®

Mouse LIX (CXCL6) (92 aa) Protein in Functional Assay (Functional)

FIGURE: 1 / 1

Mouse LIX (CXCL6) (92 aa) Protein (250-17-20UG) in Functional

Bioassay analysis of Mouse LIX (CXCL6) (92 aa) Recombinant Protein, PeproTech® (Product # 250-17-1MG).

Product Image Gallery

Product Details

250-17-20UG

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

ELISA (ELISA)

Assay-dependent

Functional Assay (Functional)

Assay-dependent

In vitro Assay (IV)

View 8 publications 8 publications

Miscellaneous PubMed (Misc)

View 2 publications 2 publications

Product Specifications

Species

Mouse

Published species

Human, Mouse

Expression System

E. coli

Amino acid sequence

APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIQKI LGSDKKKAKR NALAVERTAS VQ

Molecular weight

9.8 kDa

Class

Recombinant

Type

Protein

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Murine LIX is a 9.8 kDa protein containing 92 amino acid residues.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

CXCL6 is a chemotactic for neutrophil granulocytes. It signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Chromatin Remodeling of Colorectal Cancer Liver Metastasis is Mediated by an HGF-PU.1-DPP4 Axis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Wang L,Wang E,Prado Balcazar J,Wu Z,Xiang K,Wang Y,Huang Q,Negrete M,Chen KY,Li W,Fu Y,Dohlman A,Mines R,Zhang L,Kobayashi Y,Chen T,Shi G,Shen JP,Kopetz S,Tata PR,Moreno V,Gersbach C,Crawford G,Hsu D,Huang E,Bu P,Shen X

Fri Oct 01 00:00:00 EDT 2021

Identification of Novel Natural Substrates of Fibroblast Activation Protein-alpha by Differential Degradomics and Proteomics.

Molecular & cellular proteomics : MCP

Zhang HE,Hamson EJ,Koczorowska MM,Tholen S,Chowdhury S,Bailey CG,Lay AJ,Twigg SM,Lee Q,Roediger B,Biniossek ML,O'Rourke MB,McCaughan GW,Keane FM,Schilling O,Gorrell MD

Tue Jan 01 00:00:00 EST 2019

Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.

Scientific reports

Singh K,Davies G,Alenazi Y,Eaton JRO,Kawamura A,Bhattacharya S

Tue Jun 27 00:00:00 EDT 2017

Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.

Scientific reports

Yagawa Y,Robertson-Tessi M,Zhou SL,Anderson ARA,Mulé JJ,Mailloux AW

Wed Nov 22 00:00:00 EST 2017

CXCL5 regulates chemokine scavenging and pulmonary host defense to bacterial infection.

Immunity

Mei J,Liu Y,Dai N,Favara M,Greene T,Jeyaseelan S,Poncz M,Lee JS,Worthen GS

Fri Jul 23 00:00:00 EDT 2010

Structure and function of A41, a vaccinia virus chemokine binding protein.

PLoS pathogens

Bahar MW,Kenyon JC,Putz MM,Abrescia NG,Pease JE,Wise EL,Stuart DI,Smith GL,Grimes JM

Tue Jan 01 00:00:00 EST 2008

An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor-dependent signals.

Blood

Yu JJ,Ruddy MJ,Wong GC,Sfintescu C,Baker PJ,Smith JB,Evans RT,Gaffen SL

Tue May 01 00:00:00 EDT 2007

The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors.

The Journal of biological chemistry

Van den Steen PE,Van Aelst I,Hvidberg V,Piccard H,Fiten P,Jacobsen C,Moestrup SK,Fry S,Royle L,Wormald MR,Wallis R,Rudd PM,Dwek RA,Opdenakker G

Fri Jul 07 00:00:00 EDT 2006

Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow.

The Journal of experimental medicine

Ueda Y,Kondo M,Kelsoe G

Mon Jun 06 00:00:00 EDT 2005

Chemokine-cytokine cross-talk. The ELR+ CXC chemokine LIX (CXCL5) amplifies a proinflammatory cytokine response via a phosphatidylinositol 3-kinase-NF-kappa B pathway.

The Journal of biological chemistry

Chandrasekar B,Melby PC,Sarau HM,Raveendran M,Perla RP,Marelli-Berg FM,Dulin NO,Singh IS

Fri Feb 14 00:00:00 EST 2003

Bioinformatics

Protein Aliases: C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CKA3; CXC; CXC motif chemokine; CXCL

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Mouse LIX (CXCL6) (92 aa) Recombinant Protein, PeproTech®

Mouse LIX (CXCL6) (92 aa) Protein (250-17-20UG) in Functional

Product Details

250-17-20UG

Western Blot (WB)

ELISA (ELISA)

Functional Assay (Functional)

In vitro Assay (IV)

Miscellaneous PubMed (Misc)

Species

Published species

Expression System

Amino acid sequence

Molecular weight

Class

Type

Purity

Endotoxin concentration

Conjugate

Form

Purification

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

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