Product References
Eosinophils protect against pulmonary hypertension through 14-HDHA and 17-HDHA.
The European respiratory journal
Shu T,Zhang J,Zhou Y,Chen Z,Li J,Tang Q,Lei W,Xing Y,Wang J,Wang C
315-18 was used in In vitro experiments to show that in PH development without external inflammatory stimulus, peripheral blood exhibits a low EOS level, in which EOS play a protective role through suppressing perivascular inflammation and maintaining PASMC homeostasis via 14/17-HDHA.
Wed Mar 01 00:00:00 EST 2023
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Journal of vascular research
Chang W,Li Y,Liu F,Zang K,Zhang P,Qu S,Zhao J,Xue J
315-18 was used in Cell Culture to describe a convenient and efficient method to obtain mouse CVSMCs by enzyme digestion.
Mon Oct 30 00:00:00 EDT 2023
NR4A1 modulates intestinal smooth muscle cell phenotype and dampens inflammation-associated intestinal remodeling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Szczepanski HE,Flannigan KL,Mainoli B,Alston L,Baruta GM,Lee JW,Venu VKP,Shearer J,Dufour A,Hirota SA
315-18 was used in In vitro experiments to compare colonic smooth muscle thickening in Nr4a1+/+ and Nr4a1-/- mice using the chronic dextran sulfate sodium (DSS) model of colitis.
Tue Nov 01 00:00:00 EDT 2022
p38 MAPK priming boosts VSMC proliferation and arteriogenesis by promoting PGC1α-dependent mitochondrial dynamics.
Scientific reports
Sahún-Español Á,Clemente C,Jiménez-Loygorri JI,Sierra-Filardi E,Herrera-Melle L,Gómez-Durán A,Sabio G,Monsalve M,Boya P,Arroyo AG
315-18 was used in Sample Preparation (Western Blotting) to test the in vivo implications of this pathway in a novel conditional mouse line for selective MT4-MMP deletion in VSMCs and in mice pre-treated with the p38 MAPK activator anisomycin.
Fri Apr 08 00:00:00 EDT 2022
Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2'3'-Cyclic GMP-AMP and Cisplatin under Steady State and Inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Chen X,Wang L,Cao L,Li T,Li Z,Sun Y,Ding J,Zhou C,Xie Y,Yue N,Nan J,Jia XM,Peng C,Li H,Yang J,Xiao H
Sat May 01 00:00:00 EDT 2021
LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes.
Communications biology
Herdenberg C,Mutie PM,Billing O,Abdullah A,Strawbridge RJ,Dahlman I,Tuck S,Holmlund C,Arner P,Henriksson R,Franks PW,Hedman H
Tue Jan 19 00:00:00 EST 2021
An endogenous PI3K interactome promoting astrocyte-mediated neuroprotection identifies a novel association with RNA-binding protein ZC3H14.
The Journal of biological chemistry
Alqawlaq S,Livne-Bar I,Williams D,D'Ercole J,Leung SW,Chan D,Tuccitto A,Datti A,Wrana JL,Corbett AH,Schmitt-Ulms G,Sivak JM
Tue Aug 24 00:00:00 EDT 2021
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Nature communications
Lechertier T,Reynolds LE,Kim H,Pedrosa AR,Gómez-Escudero J,Muñoz-Félix JM,Batista S,Dukinfield M,Demircioglu F,Wong PP,Matchett KP,Henderson NC,D'Amico G,Parsons M,Harwood C,Meier P,Hodivala-Dilke KM
Thu Jun 04 00:00:00 EDT 2020
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Nature communications
Lechertier T,Reynolds LE,Kim H,Pedrosa AR,Gómez-Escudero J,Muñoz-Félix JM,Batista S,Dukinfield M,Demircioglu F,Wong PP,Matchett KP,Henderson NC,D'Amico G,Parsons M,Harwood C,Meier P,Hodivala-Dilke KM
Thu Jun 04 00:00:00 EDT 2020
microRNA-875-5p plays critical role for mesenchymal condensation in epithelial-mesenchymal interaction during tooth development.
Scientific reports
Funada K,Yoshizaki K,MIyazaki K,Han X,Yuta T,Tian T,Mizuta K,Fu Y,Iwamoto T,Yamada A,Takahashi I,Fukumoto S
Wed Mar 18 00:00:00 EDT 2020
Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches.
Immunity
Dahlgren MW,Jones SW,Cautivo KM,Dubinin A,Ortiz-Carpena JF,Farhat S,Yu KS,Lee K,Wang C,Molofsky AV,Tward AD,Krummel MF,Peng T,Molofsky AB
Tue Mar 19 00:00:00 EDT 2019
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
The Journal of clinical investigation
Stivala S,Codilupi T,Brkic S,Baerenwaldt A,Ghosh N,Hao-Shen H,Dirnhofer S,Dettmer MS,Simillion C,Kaufmann BA,Chiu S,Keller M,Kleppe M,Hilpert M,Buser AS,Passweg JR,Radimerski T,Skoda RC,Levine RL,Meyer SC
Mon Mar 04 00:00:00 EST 2019
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
The Journal of clinical investigation
Stivala S,Codilupi T,Brkic S,Baerenwaldt A,Ghosh N,Hao-Shen H,Dirnhofer S,Dettmer MS,Simillion C,Kaufmann BA,Chiu S,Keller M,Kleppe M,Hilpert M,Buser AS,Passweg JR,Radimerski T,Skoda RC,Levine RL,Meyer SC
Mon Mar 04 00:00:00 EST 2019
A stromal cell niche sustains ILC2-mediated type-2 conditioning in adipose tissue.
The Journal of experimental medicine
Rana BMJ,Jou E,Barlow JL,Rodriguez-Rodriguez N,Walker JA,Knox C,Jolin HE,Hardman CS,Sivasubramaniam M,Szeto A,Cohen ES,Scott IC,Sleeman MA,Chidomere CI,Cruz Migoni S,Caamano J,Jorgensen HF,Carobbio S,Vidal-Puig A,McKenzie ANJ
Mon Sep 02 00:00:00 EDT 2019
Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset.
Aging cell
Martini H,Iacovoni JS,Maggiorani D,Dutaur M,Marsal DJ,Roncalli J,Itier R,Dambrin C,Pizzinat N,Mialet-Perez J,Cussac D,Parini A,Lefevre L,Douin-Echinard V
Tue Oct 01 00:00:00 EDT 2019
Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium.
Investigative ophthalmology & visual science
Corliss BA,Ray HC,Mathews C,Fitzgerald K,Doty RW,Smolko CM,Shariff H,Peirce SM,Yates PA
315-18 was used in Cell Culture to establish Myh11 as a marker of a subset of corneal endothelial cells, and to demonstrate the feasibility of restoring the corneal endothelium with Myh11-lineage adipose-derived stromal cells.
Mon Dec 02 00:00:00 EST 2019
Phosphoinositide 3-kinase δ inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells.
The Journal of biological chemistry
Han H,Chen N,Huang X,Liu B,Tian J,Lei H
Fri Oct 18 00:00:00 EDT 2019
1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors.
FASEB bioAdvances
Jamali N,Song YS,Sorenson CM,Sheibani N
315-18 was used in In vitro experiments to determine the impact of 1,25(OH)2D3 on retinal pericytes prepared from wild type and VDR-deficient mice.
Mon Jul 01 00:00:00 EDT 2019
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
Thu Feb 08 00:00:00 EST 2018
Circuit Design Features of a Stable Two-Cell System.
Cell
Zhou X,Franklin RA,Adler M,Jacox JB,Bailis W,Shyer JA,Flavell RA,Mayo A,Alon U,Medzhitov R
Thu Feb 08 00:00:00 EST 2018
Lrp1 in osteoblasts controls osteoclast activity and protects against osteoporosis by limiting PDGF-RANKL signaling.
Bone research
Bartelt A,Behler-Janbeck F,Beil FT,Koehne T,Müller B,Schmidt T,Heine M,Ochs L,Yilmaz T,Dietrich M,Tuckermann JP,Amling M,Herz J,Schinke T,Heeren J,Niemeier A
Thu Oct 01 00:00:00 EDT 2020
Radiobrominated benzimidazole-quinoline derivatives as Platelet-derived growth factor receptor beta (PDGFRβ) imaging probes.
Scientific reports
Effendi N,Mishiro K,Takarada T,Makino A,Yamada D,Kitamura Y,Shiba K,Kiyono Y,Odani A,Ogawa K
Tue Jul 10 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.
Cell stem cell
Ambrosi TH,Scialdone A,Graja A,Gohlke S,Jank AM,Bocian C,Woelk L,Fan H,Logan DW,Schürmann A,Saraiva LR,Schulz TJ
315-18 was used in Cell Culture to specify the cellular identities of the adipogenic and osteogenic lineages of the bone.
Thu Jun 01 00:00:00 EDT 2017
Chebulinic acid inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression.
Scientific reports
Song IS,Jeong YJ,Park JH,Shim S,Jang SW
Mon Sep 18 00:00:00 EDT 2017
Chebulinic acid inhibits smooth muscle cell migration by suppressing PDGF-Rβ phosphorylation and inhibiting matrix metalloproteinase-2 expression.
Scientific reports
Song IS,Jeong YJ,Park JH,Shim S,Jang SW
Mon Sep 18 00:00:00 EDT 2017
A PPARγ transcriptional cascade directs adipose progenitor cell-niche interaction and niche expansion.
Nature communications
Jiang Y,Berry DC,Jo A,Tang W,Arpke RW,Kyba M,Graff JM
Mon Jun 26 00:00:00 EDT 2017
Proteomic characterization of epicardial-myocardial signaling reveals novel regulatory networks including a role for NF-κB in epicardial EMT.
PloS one
Li Y,Urban A,Midura D,Simon HG,Wang QT
315-18 was used in Cell Culture to characterise the secretome of embryonic chicken EPDC-heart explant co-cultures.
Mon Aug 28 00:00:00 EDT 2017
PDGFRα+ Cells in Embryonic Stem Cell Cultures Represent the In Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors.
Stem cell reports
Lo Nigro A,de Jaime-Soguero A,Khoueiry R,Cho DS,Ferlazzo GM,Perini I,Abon Escalona V,Aranguren XL,Chuva de Sousa Lopes SM,Koh KP,Conaldi PG,Hu WS,Zwijsen A,Lluis F,Verfaillie CM
Tue Feb 14 00:00:00 EST 2017
Fibrinolytic crosstalk with endothelial cells expands murine mesenchymal stromal cells.
Blood
Dhahri D,Sato-Kusubata K,Ohki-Koizumi M,Nishida C,Tashiro Y,Munakata S,Shimazu H,Salama Y,Eiamboonsert S,Nakauchi H,Hattori K,Heissig B
Thu Aug 25 00:00:00 EDT 2016
PLEKHG3 enhances polarized cell migration by activating actin filaments at the cell front.
Proceedings of the National Academy of Sciences of the United States of America
Nguyen TT,Park WS,Park BO,Kim CY,Oh Y,Kim JM,Choi H,Kyung T,Kim CH,Lee G,Hahn KM,Meyer T,Heo WD
Tue Sep 06 00:00:00 EDT 2016
Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD.
Proceedings of the National Academy of Sciences of the United States of America
Cortez E,Gladh H,Braun S,Bocci M,Cordero E,Björkström NK,Miyazaki H,Michael IP,Eriksson U,Folestad E,Pietras K
Tue Feb 16 00:00:00 EST 2016
Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.
Nature communications
Martino MM,Maruyama K,Kuhn GA,Satoh T,Takeuchi O,Müller R,Akira S
Tue Mar 22 00:00:00 EDT 2016
Inhibition of IL-1R1/MyD88 signalling promotes mesenchymal stem cell-driven tissue regeneration.
Nature communications
Martino MM,Maruyama K,Kuhn GA,Satoh T,Takeuchi O,Müller R,Akira S
Tue Mar 22 00:00:00 EDT 2016
PKN3 is the major regulator of angiogenesis and tumor metastasis in mice.
Scientific reports
Mukai H,Muramatsu A,Mashud R,Kubouchi K,Tsujimoto S,Hongu T,Kanaho Y,Tsubaki M,Nishida S,Shioi G,Danno S,Mehruba M,Satoh R,Sugiura R
Fri Jan 08 00:00:00 EST 2016
A Novel Protective Function of 5-Methoxytryptophan in Vascular Injury.
Scientific reports
Ho YC,Wu ML,Su CH,Chen CH,Ho HH,Lee GL,Lin WS,Lin WY,Hsu YJ,Kuo CC,Wu KK,Yet SF
Thu May 05 00:00:00 EDT 2016
Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cell, Leading to Bohring-Opitz-like Syndrome in Mice.
Stem cell reports
Zhang P,Xing C,Rhodes SD,He Y,Deng K,Li Z,He F,Zhu C,Nguyen L,Zhou Y,Chen S,Mohammad KS,Guise TA,Abdel-Wahab O,Xu M,Wang QF,Yang FC
Tue Jun 14 00:00:00 EDT 2016
Synergistic antiproliferative effect of imatinib and adriamycin in platelet-derived growth factor receptor-expressing osteosarcoma cells.
Cancer science
Yamaguchi SI,Ueki A,Sugihara E,Onishi N,Yaguchi T,Kawakami Y,Horiuchi K,Morioka H,Matsumoto M,Nakamura M,Muto A,Toyama Y,Saya H,Shimizu T
Wed Jul 01 00:00:00 EDT 2015
The combined role of galactose-deficient IgA1 and streptococcal IgA-binding M Protein in inducing IL-6 and C3 secretion from human mesangial cells: implications for IgA nephropathy.
Journal of immunology (Baltimore, Md. : 1950)
Schmitt R,Ståhl AL,Olin AI,Kristoffersson AC,Rebetz J,Novak J,Lindahl G,Karpman D
Tue Jul 01 00:00:00 EDT 2014
Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.
Blood
Olson TS,Caselli A,Otsuru S,Hofmann TJ,Williams R,Paolucci P,Dominici M,Horwitz EM
Thu Jun 27 00:00:00 EDT 2013
Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.
Blood
Olson TS,Caselli A,Otsuru S,Hofmann TJ,Williams R,Paolucci P,Dominici M,Horwitz EM
Thu Jun 27 00:00:00 EDT 2013
LRP-6 is a coreceptor for multiple fibrogenic signaling pathways in pericytes and myofibroblasts that are inhibited by DKK-1.
Proceedings of the National Academy of Sciences of the United States of America
Ren S,Johnson BG,Kida Y,Ip C,Davidson KC,Lin SL,Kobayashi A,Lang RA,Hadjantonakis AK,Moon RT,Duffield JS
Tue Jan 22 00:00:00 EST 2013
In vivo tracking of murine adipose tissue-derived multipotent adult stem cells and ex vivo cross-validation.
International journal of molecular imaging
Garrovo C,Bergamin N,Bates D,Cesselli D,Beltrami AP,Lorenzon A,Ferrari R,Alberto Beltrami C,Lorusso V,Biffi S
Wed Feb 13 00:00:00 EST 2013
The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells.
PloS one
Takeichi M,Nimura K,Mori M,Nakagami H,Kaneda Y
Thu Aug 29 00:00:00 EDT 2013
Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.
The Journal of biological chemistry
Sanematsu F,Nishikimi A,Watanabe M,Hongu T,Tanaka Y,Kanaho Y,Côté JF,Fukui Y
Fri Mar 22 00:00:00 EDT 2013
Agrin regulates CLASP2-mediated capture of microtubules at the neuromuscular junction synaptic membrane.
The Journal of cell biology
Schmidt N,Basu S,Sladecek S,Gatti S,van Haren J,Treves S,Pielage J,Galjart N,Brenner HR
Mon Aug 06 00:00:00 EDT 2012
Inhibition of epidermal growth factor receptor tyrosine kinase ameliorates collagen-induced arthritis.
Journal of immunology (Baltimore, Md. : 1950)
Swanson CD,Akama-Garren EH,Stein EA,Petralia JD,Ruiz PJ,Edalati A,Lindstrom TM,Robinson WH
Sun Apr 01 00:00:00 EDT 2012
Over-expression of PDGFR-β promotes PDGF-induced proliferation, migration, and angiogenesis of EPCs through PI3K/Akt signaling pathway.
PloS one
Wang H,Yin Y,Li W,Zhao X,Yu Y,Zhu J,Qin Z,Wang Q,Wang K,Lu W,Liu J,Huang L
Mon Jun 18 00:00:00 EDT 2012
Combination of a ptgs2 inhibitor and an epidermal growth factor receptor-signaling inhibitor prevents tumorigenesis of oligodendrocyte lineage-derived glioma-initiating cells.
Stem cells (Dayton, Ohio)
Hide T,Takezaki T,Nakatani Y,Nakamura H,Kuratsu J,Kondo T
Fri Apr 01 00:00:00 EDT 2011
Cutting edge: Calcium/Calmodulin-dependent protein kinase type IV is essential for mesangial cell proliferation and lupus nephritis.
Journal of immunology (Baltimore, Md. : 1950)
Ichinose K,Rauen T,Juang YT,Kis-Toth K,Mizui M,Koga T,Tsokos GC
Thu Dec 01 00:00:00 EST 2011
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche.
Nature
Méndez-Ferrer S,Michurina TV,Ferraro F,Mazloom AR,Macarthur BD,Lira SA,Scadden DT,Ma'ayan A,Enikolopov GN,Frenette PS
Thu Aug 12 00:00:00 EDT 2010
Erythropoietin accelerates smooth muscle cell-rich vascular lesion formation in mice through endothelial cell activation involving enhanced PDGF-BB release.
Blood
Janmaat ML,Heerkens JL,de Bruin AM,Klous A,de Waard V,de Vries CJ
Thu Feb 18 00:00:00 EST 2010
Stimulation of platelet-derived growth factor receptor beta (PDGFRbeta) activates ADAM17 and promotes metalloproteinase-dependent cross-talk between the PDGFRbeta and epidermal growth factor receptor (EGFR) signaling pathways.
The Journal of biological chemistry
Mendelson K,Swendeman S,Saftig P,Blobel CP
Fri Aug 06 00:00:00 EDT 2010
A role for VEGF as a negative regulator of pericyte function and vessel maturation.
Nature
Greenberg JI,Shields DJ,Barillas SG,Acevedo LM,Murphy E,Huang J,Scheppke L,Stockmann C,Johnson RS,Angle N,Cheresh DA
Thu Dec 11 00:00:00 EST 2008
Methylxanthines inhibit glucose transport in rat adipocytes by two independent mechanisms.
Biochemical pharmacology
Steinfelder HJ,Pethö-Schramm S
Sat Sep 01 00:00:00 EDT 1990
