Product References
Prdm14 promotes mouse ESC self-renewal and PGCLC specification through enhancement of Stat3 activity.
iScience
Li Y,Yang Z,Li X,Yu Y,Li X,Chen P,Li B,Wang X,Ye SD
AF-250-03 was used in Sample Preparation (FC/FACS) to study the downstream mechanism of Prdm14 involved in the maintenance of mouse embryonic stem cell (mESC) pluripotency and the specification of primordial germ cells (PGCs) using high-throughput sequencing, chromatin immunoprecipitation, and luciferase reporter assays. To demonstrate that Prdm14 directly binds to the promoter of Socs3 and represses its transcription to increase the phosphorylation level of Stat3 protein, a critical downstream
Fri Nov 18 00:00:00 EST 2022
Aged skeletal stem cells generate an inflammatory degenerative niche.
Nature
Ambrosi TH,Marecic O,McArdle A,Sinha R,Gulati GS,Tong X,Wang Y,Steininger HM,Hoover MY,Koepke LS,Murphy MP,Sokol J,Seo EY,Tevlin R,Lopez M,Brewer RE,Mascharak S,Lu L,Ajanaku O,Conley SD,Seita J,Morri M,Neff NF,Sahoo D,Yang F,Weissman IL,Longaker MT,Chan CKF
Wed Sep 01 00:00:00 EDT 2021
Default polyfunctional T helper 1 response to ample signal 1 alone.
Cellular & molecular immunology
Danelli L,Cornish G,Merkenschlager J,Kassiotis G
Thu Jul 01 00:00:00 EDT 2021
Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation.
iScience
Nguyen GT,Xu S,Adams W,Leong JM,Bunnell SC,Mansour MK,Sykes DB,Mecsas J
Fri Aug 20 00:00:00 EDT 2021
The transcription factor Tfcp2l1 promotes primordial germ cell-like cell specification of pluripotent stem cells.
The Journal of biological chemistry
Zhang M,Ji J,Wang X,Zhang X,Zhang Y,Li Y,Wang X,Li X,Ban Q,Ye SD
Fri Oct 01 00:00:00 EDT 2021
Non-conditioned bone marrow chimeric mouse generation using culture-based enrichment of hematopoietic stem and progenitor cells.
Nature communications
Ochi K,Morita M,Wilkinson AC,Iwama A,Yamazaki S
Fri Jun 11 00:00:00 EDT 2021
Embryonic endothelial evolution towards first hematopoietic stem cells revealed by single-cell transcriptomic and functional analyses.
Cell research
Hou S,Li Z,Zheng X,Gao Y,Dong J,Ni Y,Wang X,Li Y,Ding X,Chang Z,Li S,Hu Y,Fan X,Hou Y,Wen L,Liu B,Tang F,Lan Y
Fri May 01 00:00:00 EDT 2020
Long-term ex vivo expansion of mouse hematopoietic stem cells.
Nature protocols
Wilkinson AC,Ishida R,Nakauchi H,Yamazaki S
Sat Feb 01 00:00:00 EST 2020
Androgen Receptor Signaling Positively Regulates Monocytic Development.
Frontiers in immunology
Consiglio CR,Gollnick SO
AF-250-03 was used in In vitro experiments to investigate the role of androgen signaling in monocytic differentiation with a genetic mouse model of myeloid androgen receptor (AR) knockout (MARKO) and pharmacological inhibition of AR.
Thu Apr 29 00:00:00 EDT 2021
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia.
Nature communications
Minuesa G,Albanese SK,Xie W,Kazansky Y,Worroll D,Chow A,Schurer A,Park SM,Rotsides CZ,Taggart J,Rizzi A,Naden LN,Chou T,Gourkanti S,Cappel D,Passarelli MC,Fairchild L,Adura C,Glickman JF,Schulman J,Famulare C,Patel M,Eibl JK,Ross GM,Bhattacharya S,Tan DS,Leslie CS,Beuming T,Patel DJ,Goldgur Y,Chodera JD,Kharas MG
Wed Jun 19 00:00:00 EDT 2019
SOCS2 is part of a highly prognostic 4-gene signature in AML and promotes disease aggressiveness.
Scientific reports
Nguyen CH,Glüxam T,Schlerka A,Bauer K,Grandits AM,Hackl H,Dovey O,Zöchbauer-Müller S,Cooper JL,Vassiliou GS,Stoiber D,Wieser R,Heller G
Mon Jun 24 00:00:00 EDT 2019
Notch-Expanded Murine Hematopoietic Stem and Progenitor Cells Mitigate Death from Lethal Radiation and Convey Immune Tolerance in Mismatched Recipients.
Stem cells translational medicine
Milano F,Merriam F,Nicoud I,Li J,Gooley TA,Heimfeld S,Imren S,Delaney C
Wed Feb 01 00:00:00 EST 2017
Role of Erk1/2 signaling in the regulation of neutrophil versus monocyte development in response to G-CSF and M-CSF.
The Journal of biological chemistry
Hu N,Qiu Y,Dong F
Fri Oct 02 00:00:00 EDT 2015
Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk.
The Journal of clinical investigation
Staser K,Park SJ,Rhodes SD,Zeng Y,He YZ,Shew MA,Gehlhausen JR,Cerabona D,Menon K,Chen S,Sun Z,Yuan J,Ingram DA,Nalepa G,Yang FC,Clapp DW
Tue Jan 01 00:00:00 EST 2013
SOCS2 is dispensable for BCR/ABL1-induced chronic myeloid leukemia-like disease and for normal hematopoietic stem cell function.
Leukemia
Hansen N,Ågerstam H,Wahlestedt M,Landberg N,Askmyr M,Ehinger M,Rissler M,Lilljebjörn H,Johnels P,Ishiko J,Melo JV,Alexander WS,Bryder D,Järås M,Fioretos T
Tue Jan 01 00:00:00 EST 2013
Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling.
Proceedings of the National Academy of Sciences of the United States of America
Jin HS,Liao L,Park Y,Liu YC
Tue Jan 08 00:00:00 EST 2013
MiR-223 deficiency increases eosinophil progenitor proliferation.
Journal of immunology (Baltimore, Md. : 1950)
Lu TX,Lim EJ,Besse JA,Itskovich S,Plassard AJ,Fulkerson PC,Aronow BJ,Rothenberg ME
Fri Feb 15 00:00:00 EST 2013
Pak2 kinase restrains mast cell FcεRI receptor signaling through modulation of Rho protein guanine nucleotide exchange factor (GEF) activity.
The Journal of biological chemistry
Kosoff R,Chow HY,Radu M,Chernoff J
Fri Jan 11 00:00:00 EST 2013
Heparan sulfate 6-O-sulfotransferase isoform-dependent regulatory effects of heparin on the activities of various proteases in mast cells and the biosynthesis of 6-O-sulfated heparin.
The Journal of biological chemistry
Anower-E-Khuda MF,Habuchi H,Nagai N,Habuchi O,Yokochi T,Kimata K
Fri Feb 08 00:00:00 EST 2013
Controlling long-range genomic interactions at a native locus by targeted tethering of a looping factor.
Cell
Deng W,Lee J,Wang H,Miller J,Reik A,Gregory PD,Dean A,Blobel GA
Fri Jun 08 00:00:00 EDT 2012
An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia.
Cancer cell
Gruber TA,Larson Gedman A,Zhang J,Koss CS,Marada S,Ta HQ,Chen SC,Su X,Ogden SK,Dang J,Wu G,Gupta V,Andersson AK,Pounds S,Shi L,Easton J,Barbato MI,Mulder HL,Manne J,Wang J,Rusch M,Ranade S,Ganti R,Parker M,Ma J,Radtke I,Ding L,Cazzaniga G,Biondi A,Kornblau SM,Ravandi F,Kantarjian H,Nimer SD,Döhner K,Döhner H,Ley TJ,Ballerini P,Shurtleff S,Tomizawa D,Adachi S,Hayashi Y,Tawa A,Shih LY,Liang DC,Rubnitz JE,Pui CH,Mardis ER,Wilson RK,Downing JR
Tue Nov 13 00:00:00 EST 2012
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia.
Blood
Tanaka S,Miyagi S,Sashida G,Chiba T,Yuan J,Mochizuki-Kashio M,Suzuki Y,Sugano S,Nakaseko C,Yokote K,Koseki H,Iwama A
Thu Aug 02 00:00:00 EDT 2012
Adaptor protein Lnk binds to and inhibits normal and leukemic FLT3.
Blood
Lin DC,Yin T,Koren-Michowitz M,Ding LW,Gueller S,Gery S,Tabayashi T,Bergholz U,Kazi JU,Rönnstrand L,Stocking C,Koeffler HP
Thu Oct 18 00:00:00 EDT 2012
EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress.
Blood
Peslak SA,Wenger J,Bemis JC,Kingsley PD,Koniski AD,McGrath KE,Palis J
Thu Sep 20 00:00:00 EDT 2012
Emergence of NK-cell progenitors and functionally competent NK-cell lineage subsets in the early mouse embryo.
Blood
Tang Y,Peitzsch C,Charoudeh HN,Cheng M,Chaves P,Jacobsen SE,Sitnicka E
Thu Jul 05 00:00:00 EDT 2012
Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis.
Blood
Yuan H,Wang Z,Li L,Zhang H,Modi H,Horne D,Bhatia R,Chen W
Thu Feb 23 00:00:00 EST 2012
SOCS1 cooperates with FLT3-ITD in the development of myeloproliferative disease by promoting the escape from external cytokine control.
Blood
Reddy PN,Sargin B,Choudhary C,Stein S,Grez M,Müller-Tidow C,Berdel WE,Serve H,Brandts CH
Thu Aug 23 00:00:00 EDT 2012
Bcl-2, Bcl-x(L), and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells.
Blood
Mérino D,Khaw SL,Glaser SP,Anderson DJ,Belmont LD,Wong C,Yue P,Robati M,Phipson B,Fairlie WD,Lee EF,Campbell KJ,Vandenberg CJ,Cory S,Roberts AW,Ludlam MJ,Huang DC,Bouillet P
Thu Jun 14 00:00:00 EDT 2012
Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cells.
Blood
Zhang Y,Yan X,Sashida G,Zhao X,Rao Y,Goyama S,Whitman SP,Zorko N,Bernot K,Conway RM,Witte D,Wang QF,Tenen DG,Xiao Z,Marcucci G,Mulloy JC,Grimes HL,Caligiuri MA,Huang G
Thu Aug 02 00:00:00 EDT 2012
KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice.
Blood
Zhao L,Melenhorst JJ,Alemu L,Kirby M,Anderson S,Kench M,Hoogstraten-Miller S,Brinster L,Kamikubo Y,Gilliland DG,Liu PP
Thu Feb 09 00:00:00 EST 2012
Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.
Blood
Cai M,Langer EM,Gill JG,Satpathy AT,Albring JC,KC W,Murphy TL,Murphy KM
Thu Jul 12 00:00:00 EDT 2012
Activated Gs signaling in osteoblastic cells alters the hematopoietic stem cell niche in mice.
Blood
Schepers K,Hsiao EC,Garg T,Scott MJ,Passegué E
Thu Oct 25 00:00:00 EDT 2012
FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.
Blood
Itkin T,Ludin A,Gradus B,Gur-Cohen S,Kalinkovich A,Schajnovitz A,Ovadya Y,Kollet O,Canaani J,Shezen E,Coffin DJ,Enikolopov GN,Berg T,Piacibello W,Hornstein E,Lapidot T
Thu Aug 30 00:00:00 EDT 2012
FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.
Blood
Itkin T,Ludin A,Gradus B,Gur-Cohen S,Kalinkovich A,Schajnovitz A,Ovadya Y,Kollet O,Canaani J,Shezen E,Coffin DJ,Enikolopov GN,Berg T,Piacibello W,Hornstein E,Lapidot T
Thu Aug 30 00:00:00 EDT 2012
Critical role of P1-Runx1 in mouse basophil development.
Blood
Mukai K,BenBarak MJ,Tachibana M,Nishida K,Karasuyama H,Taniuchi I,Galli SJ
Thu Jul 05 00:00:00 EDT 2012
Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function.
Blood
Schuettpelz LG,Gopalan PK,Giuste FO,Romine MP,van Os R,Link DC
Thu Oct 11 00:00:00 EDT 2012
PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.
Blood
van de Laar L,van den Bosch A,Boonstra A,Binda RS,Buitenhuis M,Janssen HL,Coffer PJ,Woltman AM
Thu Dec 13 00:00:00 EST 2012
Necdin, a p53 target gene, regulates the quiescence and response to genotoxic stress of hematopoietic stem/progenitor cells.
Blood
Asai T,Liu Y,Di Giandomenico S,Bae N,Ndiaye-Lobry D,Deblasio A,Menendez S,Antipin Y,Reva B,Wevrick R,Nimer SD
Thu Aug 23 00:00:00 EDT 2012
Spry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.
Blood
Sathyanarayana P,Dev A,Pradeep A,Ufkin M,Licht JD,Wojchowski DM
Thu Jun 07 00:00:00 EDT 2012
Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.
Blood
Chang KH,Sanchez-Aguilera A,Shen S,Sengupta A,Madhu MN,Ficker AM,Dunn SK,Kuenzi AM,Arnett JL,Santho RA,Agirre X,Perentesis JP,Deininger MW,Zheng Y,Bustelo XR,Williams DA,Cancelas JA
Thu Jul 26 00:00:00 EDT 2012
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.
The Journal of clinical investigation
Sugimoto K,Kudo M,Sundaram A,Ren X,Huang K,Bernstein X,Wang Y,Raymond WW,Erle DJ,Abrink M,Caughey GH,Huang X,Sheppard D
Wed Feb 01 00:00:00 EST 2012
Crucial role of SLP-76 and ADAP for neutrophil recruitment in mouse kidney ischemia-reperfusion injury.
The Journal of experimental medicine
Block H,Herter JM,Rossaint J,Stadtmann A,Kliche S,Lowell CA,Zarbock A
Mon Feb 13 00:00:00 EST 2012
Zbtb46 expression distinguishes classical dendritic cells and their committed progenitors from other immune lineages.
The Journal of experimental medicine
Satpathy AT,KC W,Albring JC,Edelson BT,Kretzer NM,Bhattacharya D,Murphy TL,Murphy KM
Mon Jun 04 00:00:00 EDT 2012
Lethal myelofibrosis induced by Bmi1-deficient hematopoietic cells unveils a tumor suppressor function of the polycomb group genes.
The Journal of experimental medicine
Oguro H,Yuan J,Tanaka S,Miyagi S,Mochizuki-Kashio M,Ichikawa H,Yamazaki S,Koseki H,Nakauchi H,Iwama A
Mon Mar 12 00:00:00 EDT 2012
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation.
The Journal of experimental medicine
Nowak EC,de Vries VC,Wasiuk A,Ahonen C,Bennett KA,Le Mercier I,Ha DG,Noelle RJ
Mon Oct 22 00:00:00 EDT 2012
ZBTB1 is a determinant of lymphoid development.
The Journal of experimental medicine
Siggs OM,Li X,Xia Y,Beutler B
Mon Jan 16 00:00:00 EST 2012
Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.
Proceedings of the National Academy of Sciences of the United States of America
Taniguchi Ishikawa E,Gonzalez-Nieto D,Ghiaur G,Dunn SK,Ficker AM,Murali B,Madhu M,Gutstein DE,Fishman GI,Barrio LC,Cancelas JA
Tue Jun 05 00:00:00 EDT 2012
p85β phosphoinositide 3-kinase subunit regulates tumor progression.
Proceedings of the National Academy of Sciences of the United States of America
Cortés I,Sánchez-Ruíz J,Zuluaga S,Calvanese V,Marqués M,Hernández C,Rivera T,Kremer L,González-García A,Carrera AC
Tue Jul 10 00:00:00 EDT 2012
Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.
Proceedings of the National Academy of Sciences of the United States of America
Zandi S,Ahsberg J,Tsapogas P,Stjernberg J,Qian H,Sigvardsson M
Tue Sep 25 00:00:00 EDT 2012
Complex oncogene dependence in microRNA-125a-induced myeloproliferative neoplasms.
Proceedings of the National Academy of Sciences of the United States of America
Guo S,Bai H,Megyola CM,Halene S,Krause DS,Scadden DT,Lu J
Tue Oct 09 00:00:00 EDT 2012
Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interaction.
Proceedings of the National Academy of Sciences of the United States of America
Cunningham L,Finckbeiner S,Hyde RK,Southall N,Marugan J,Yedavalli VR,Dehdashti SJ,Reinhold WC,Alemu L,Zhao L,Yeh JR,Sood R,Pommier Y,Austin CP,Jeang KT,Zheng W,Liu P
Tue Sep 04 00:00:00 EDT 2012
Direct Toll-like receptor-mediated stimulation of hematopoietic stem and progenitor cells occurs in vivo and promotes differentiation toward macrophages.
Stem cells (Dayton, Ohio)
Megías J,Yáñez A,Moriano S,O'Connor JE,Gozalbo D,Gil ML
Sun Jul 01 00:00:00 EDT 2012
Amniotic fluid stem cells restore the muscle cell niche in a HSA-Cre, Smn(F7/F7) mouse model.
Stem cells (Dayton, Ohio)
Piccoli M,Franzin C,Bertin E,Urbani L,Blaauw B,Repele A,Taschin E,Cenedese A,Zanon GF,André-Schmutz I,Rosato A,Melki J,Cavazzana-Calvo M,Pozzobon M,De Coppi P
Wed Aug 01 00:00:00 EDT 2012
NLRP3 inflammasome activity is negatively controlled by miR-223.
Journal of immunology (Baltimore, Md. : 1950)
Bauernfeind F,Rieger A,Schildberg FA,Knolle PA,Schmid-Burgk JL,Hornung V
Mon Oct 15 00:00:00 EDT 2012
Regulation of B cell linker protein transcription by PU.1 and Spi-B in murine B cell acute lymphoblastic leukemia.
Journal of immunology (Baltimore, Md. : 1950)
Xu LS,Sokalski KM,Hotke K,Christie DA,Zarnett O,Piskorz J,Thillainadesan G,Torchia J,DeKoter RP
Mon Oct 01 00:00:00 EDT 2012
Regulation of eosinophil trafficking by SWAP-70 and its role in allergic airway inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Bahaie NS,Hosseinkhani MR,Ge XN,Kang BN,Ha SG,Blumenthal MS,Jessberger R,Rao SP,Sriramarao P
Wed Feb 01 00:00:00 EST 2012
Stem cell factor programs the mast cell activation phenotype.
Journal of immunology (Baltimore, Md. : 1950)
Ito T,Smrž D,Jung MY,Bandara G,Desai A,Smržová Š,Kuehn HS,Beaven MA,Metcalfe DD,Gilfillan AM
Fri Jun 01 00:00:00 EDT 2012
Direct reduction of antigen receptor expression in polyclonal B cell populations developing in vivo results in light chain receptor editing.
Journal of immunology (Baltimore, Md. : 1950)
Shen S,Manser T
Sun Jan 01 00:00:00 EST 2012
CD11c+ cells are required for antigen-induced increase of mast cells in the lung.
Journal of immunology (Baltimore, Md. : 1950)
Dahlin JS,Feinstein R,Cui Y,Heyman B,Hallgren J
Mon Oct 15 00:00:00 EDT 2012
Sphingosine kinase-1-dependent and -independent inhibitory effects of zanthoxyli fructus to attenuate the activation of mucosal mast cells and ameliorate food allergies in mice.
Evidence-based complementary and alternative medicine : eCAM
Wang X,Kageyama-Yahara N,Hayashi S,Yamamoto T,Kadowaki M
Thu Aug 23 00:00:00 EDT 2012
Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line.
PLoS genetics
Wu JQ,Seay M,Schulz VP,Hariharan M,Tuck D,Lian J,Du J,Shi M,Ye Z,Gerstein M,Snyder MP,Weissman S
Tue Sep 04 00:00:00 EDT 2012
The notch ligand delta-like 4 regulates multiple stages of early hemato-vascular development.
PloS one
Laranjeiro R,Alcobia I,Neves H,Gomes AC,Saavedra P,Carvalho CC,Duarte A,Cidadão A,Parreira L
Thu Aug 30 00:00:00 EDT 2012
Interferon-γ-producing immature myeloid cells confer protection against severe invasive group A Streptococcus infections.
Nature communications
Matsumura T,Ato M,Ikebe T,Ohnishi M,Watanabe H,Kobayashi K
Tue Feb 14 00:00:00 EST 2012
TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms.
PloS one
Takaesu G,Inagaki M,Takubo K,Mishina Y,Hess PR,Dean GA,Yoshimura A,Matsumoto K,Suda T,Ninomiya-Tsuji J
Tue May 28 00:00:00 EDT 2013
Bmi1 confers resistance to oxidative stress on hematopoietic stem cells.
PloS one
Nakamura S,Oshima M,Yuan J,Saraya A,Miyagi S,Konuma T,Yamazaki S,Osawa M,Nakauchi H,Koseki H,Iwama A
Tue Oct 16 00:00:00 EDT 2012
Genetic evidence for critical roles of P38α protein in regulating mast cell differentiation and chemotaxis through distinct mechanisms.
The Journal of biological chemistry
Hu P,Carlesso N,Xu M,Liu Y,Nebreda AR,Takemoto C,Kapur R
Fri Jun 08 00:00:00 EDT 2012
The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells.
PloS one
Yamada T,Park CS,Burns A,Nakada D,Lacorazza HD
Mon Oct 22 00:00:00 EDT 2012
FcεR1-mediated mast cell reactivity is amplified through prolonged Toll-like receptor-ligand treatment.
PloS one
Saluja R,Delin I,Nilsson GP,Adner M
Wed Jan 16 00:00:00 EST 2013
Defining the molecular role of gp91phox in the immune manifestation of acute allergic asthma using a preclinical murine model.
Clinical and molecular allergy : CMA
Banerjee ER,Henderson WR
Wed Jan 04 00:00:00 EST 2012
IL-4 engagement of the type I IL-4 receptor complex enhances mouse eosinophil migration to eotaxin-1 in vitro.
PloS one
Heller NM,Gwinn WM,Donnelly RP,Constant SL,Keegan AD
Fri Jan 04 00:00:00 EST 2013
A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo.
PloS one
Dahlke C,Maul K,Christalla T,Walz N,Schult P,Stocking C,Grundhoff A
Wed May 22 00:00:00 EDT 2013
Induction of histiocytic sarcoma in mouse skeletal muscle.
PloS one
Liu J,Hettmer S,Milsom MD,Hofmann I,Hua F,Miller C,Bronson RT,Wagers AJ
Thu Feb 07 00:00:00 EST 2013
The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression.
The Journal of biological chemistry
Haining EJ,Yang J,Bailey RL,Khan K,Collier R,Tsai S,Watson SP,Frampton J,Garcia P,Tomlinson MG
Fri Nov 16 00:00:00 EST 2012
Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.
PloS one
Yamaguchi T,Hamanaka S,Kamiya A,Okabe M,Kawarai M,Wakiyama Y,Umino A,Hayama T,Sato H,Lee YS,Kato-Itoh M,Masaki H,Kobayashi T,Yamazaki S,Nakauchi H
Wed Jan 16 00:00:00 EST 2013
Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.
PloS one
Yamaguchi T,Hamanaka S,Kamiya A,Okabe M,Kawarai M,Wakiyama Y,Umino A,Hayama T,Sato H,Lee YS,Kato-Itoh M,Masaki H,Kobayashi T,Yamazaki S,Nakauchi H
Wed Jan 16 00:00:00 EST 2013
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Cancer cell
Mali RS,Ramdas B,Ma P,Shi J,Munugalavadla V,Sims E,Wei L,Vemula S,Nabinger SC,Goodwin CB,Chan RJ,Traina F,Visconte V,Tiu RV,Lewis TA,Stern AM,Wen Q,Crispino JD,Boswell HS,Kapur R
Tue Sep 13 00:00:00 EDT 2011
Macrophage development from HSCs requires PU.1-coordinated microRNA expression.
Blood
Ghani S,Riemke P,Schönheit J,Lenze D,Stumm J,Hoogenkamp M,Lagendijk A,Heinz S,Bonifer C,Bakkers J,Abdelilah-Seyfried S,Hummel M,Rosenbauer F
Thu Aug 25 00:00:00 EDT 2011
PTEN deficiency in mast cells causes a mastocytosis-like proliferative disease that heightens allergic responses and vascular permeability.
Blood
Furumoto Y,Charles N,Olivera A,Leung WH,Dillahunt S,Sargent JL,Tinsley K,Odom S,Scott E,Wilson TM,Ghoreschi K,Kneilling M,Chen M,Lee DM,Bolland S,Rivera J
Thu Nov 17 00:00:00 EST 2011
Crosstalk between NOTCH and AKT signaling during murine megakaryocyte lineage specification.
Blood
Cornejo MG,Mabialah V,Sykes SM,Khandan T,Lo Celso C,Lopez CK,Rivera-Muñoz P,Rameau P,Tothova Z,Aster JC,DePinho RA,Scadden DT,Gilliland DG,Mercher T
Thu Aug 04 00:00:00 EDT 2011
Identification of Flt3⁺CD150⁻ myeloid progenitors in adult mouse bone marrow that harbor T lymphoid developmental potential.
Blood
Chi AW,Chavez A,Xu L,Weber BN,Shestova O,Schaffer A,Wertheim G,Pear WS,Izon D,Bhandoola A
Thu Sep 08 00:00:00 EDT 2011
IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.
Blood
Tsapogas P,Zandi S,Åhsberg J,Zetterblad J,Welinder E,Jönsson JI,Månsson R,Qian H,Sigvardsson M
Thu Aug 04 00:00:00 EDT 2011
The PI3K pathway drives the maturation of mast cells via microphthalmia transcription factor.
Blood
Ma P,Mali RS,Munugalavadla V,Krishnan S,Ramdas B,Sims E,Martin H,Ghosh J,Li S,Chan RJ,Krystal G,Craig AW,Takemoto C,Kapur R
Thu Sep 29 00:00:00 EDT 2011
Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.
Blood
Jaako P,Flygare J,Olsson K,Quere R,Ehinger M,Henson A,Ellis S,Schambach A,Baum C,Richter J,Larsson J,Bryder D,Karlsson S
Thu Dec 01 00:00:00 EST 2011
Impact of gene dosage, loss of wild-type allele, and FLT3 ligand on Flt3-ITD-induced myeloproliferation.
Blood
Kharazi S,Mead AJ,Mansour A,Hultquist A,Böiers C,Luc S,Buza-Vidas N,Ma Z,Ferry H,Atkinson D,Reckzeh K,Masson K,Cammenga J,Rönnstrand L,Arai F,Suda T,Nerlov C,Sitnicka E,Jacobsen SE
Thu Sep 29 00:00:00 EDT 2011
Δ12-prostaglandin J3, an omega-3 fatty acid-derived metabolite, selectively ablates leukemia stem cells in mice.
Blood
Hegde S,Kaushal N,Ravindra KC,Chiaro C,Hafer KT,Gandhi UH,Thompson JT,van den Heuvel JP,Kennett MJ,Hankey P,Paulson RF,Prabhu KS
Thu Dec 22 00:00:00 EST 2011
The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal.
Blood
Wang J,Han F,Wu J,Lee SW,Chan CH,Wu CY,Yang WL,Gao Y,Zhang X,Jeong YS,Moten A,Samaniego F,Huang P,Liu Q,Zeng YX,Lin HK
Thu Nov 17 00:00:00 EST 2011
SHP2 tyrosine phosphatase stimulates CEBPA gene expression to mediate cytokine-dependent granulopoiesis.
Blood
Zhang L,Friedman AD
Thu Aug 25 00:00:00 EDT 2011
Memory T cells from minor histocompatibility antigen-vaccinated and virus-immune donors improve GVL and immune reconstitution.
Blood
Li N,Matte-Martone C,Zheng H,Cui W,Venkatesan S,Tan HS,McNiff J,Demetris AJ,Roopenian D,Kaech S,Shlomchik WD
Thu Nov 24 00:00:00 EST 2011
Candida albicans induces selective development of macrophages and monocyte derived dendritic cells by a TLR2 dependent signalling.
PloS one
Yáñez A,Megías J,O'Connor JE,Gozalbo D,Gil ML
Tue Feb 28 00:00:00 EST 2012
ISG15 modulates development of the erythroid lineage.
PloS one
Maragno AL,Pironin M,Alcalde H,Cong X,Knobeloch KP,Tangy F,Zhang DE,Ghysdael J,Quang CT
Fri Feb 17 00:00:00 EST 2012
MiR-221 influences effector functions and actin cytoskeleton in mast cells.
PloS one
Mayoral RJ,Deho L,Rusca N,Bartonicek N,Saini HK,Enright AJ,Monticelli S
Fri Feb 17 00:00:00 EST 2012
Requirement of interaction between mast cells and skin dendritic cells to establish contact hypersensitivity.
PloS one
Otsuka A,Kubo M,Honda T,Egawa G,Nakajima S,Tanizaki H,Kim B,Matsuoka S,Watanabe T,Nakae S,Miyachi Y,Kabashima K
Thu Jan 26 00:00:00 EST 2012
Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.
The Journal of biological chemistry
Dagälv A,Holmborn K,Kjellén L,Abrink M
Fri Dec 30 00:00:00 EST 2011
Magnetic resonance imaging of bone marrow cell-mediated interleukin-10 gene therapy of atherosclerosis.
PloS one
Sun J,Li X,Feng H,Gu H,Blair T,Li J,Soriano S,Meng Y,Zhang F,Feng Q,Yang X
Tue Feb 14 00:00:00 EST 2012
Differential Secondary Reconstitution of In Vivo-Selected Human SCID-Repopulating Cells in NOD/SCID versus NOD/SCID/γ chain Mice.
Bone marrow research
Cai S,Wang H,Bailey B,Hartwell JR,Silver JM,Juliar BE,Sinn AL,Baluyut AR,Pollok KE
Thu Nov 10 00:00:00 EST 2011
Single cell analysis facilitates staging of Blimp1-dependent primordial germ cells derived from mouse embryonic stem cells.
PloS one
Vincent JJ,Li Z,Lee SA,Liu X,Etter MO,Diaz-Perez SV,Taylor SK,Gkountela S,Lindgren AG,Clark AT
Mon Aug 27 00:00:00 EDT 2012
Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells.
Journal of immunotherapy (Hagerstown, Md. : 1997)
Wrzesinski C,Paulos CM,Kaiser A,Muranski P,Palmer DC,Gattinoni L,Yu Z,Rosenberg SA,Restifo NP
Fri Jan 01 00:00:00 EST 2010
