Product References
VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes.
mBio
Lu SL,Omori H,Zhou Y,Lin YS,Liu CC,Wu JJ,Noda T
450-32 was used in In vivo experiments to reveal that administration of VEGF augmented both xenophagy and lysosomal activity in these cells, leading to the efficient killing of intracellular GAS.
Tue Aug 30 00:00:00 EDT 2022
DRG2 Depletion Promotes Endothelial Cell Senescence and Vascular Endothelial Dysfunction.
International journal of molecular sciences
Le AN,Park SS,Le MX,Lee UH,Ko BK,Lim HR,Yu R,Choi SH,Lee BJ,Ham SY,Ha CM,Park JW
450-32 was used in In vitro experiments to show that deficiency of developmentally regulated GTP-binding protein 2 (DRG2) induces senescence and dysfunction of endothelial cells, suggesting that DRG2 is a key regulator of endothelial senescence, and its downregulation is probably involved in vascular dysfunction and diseases.
Sun Mar 06 00:00:00 EST 2022
Exosomal EPHA2 derived from highly metastatic breast cancer cells promotes angiogenesis by activating the AMPK signaling pathway through Ephrin A1-EPHA2 forward signaling.
Theranostics
Han B,Zhang H,Tian R,Liu H,Wang Z,Wang Z,Tian J,Cui Y,Ren S,Zuo X,Tian R,Niu R,Zhang F
450-32 was used in In vivo experiments to identify a novel mechanism of exosomal EPHA2-mediated intercellular communication from breast cancer cells to endothelial cells in the tumor microenvironment to provoke angiogenesis and metastasis.
Thu Jun 09 00:00:00 EDT 2022
Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation.
Hepatology (Baltimore, Md.)
Colucci S,Altamura S,Marques O,Dropmann A,Horvat NK,Müdder K,Hammad S,Dooley S,Muckenthaler MU
Fri Oct 01 00:00:00 EDT 2021
EVL regulates VEGF receptor-2 internalization and signaling in developmental angiogenesis.
EMBO reports
Zink J,Frye M,Frömel T,Carlantoni C,John D,Schreier D,Weigert A,Laban H,Salinas G,Stingl H,Günther L,Popp R,Hu J,Vanhollebeke B,Schmidt H,Acker-Palmer A,Renné T,Fleming I,Benz PM
Wed Feb 03 00:00:00 EST 2021
Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis.
EMBO reports
Nitzsche A,Pietilä R,Love DT,Testini C,Ninchoji T,Smith RO,Ekvärn E,Larsson J,Roche FP,Egaña I,Jauhiainen S,Berger P,Claesson-Welsh L,Hellström M
Wed Feb 03 00:00:00 EST 2021
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis.
Journal of cell science
Tsuji-Tamura K,Morino-Koga S,Suzuki S,Ogawa M
450-32 was used in Sample Preparation (FC/FACS) to study the molecular mechanisms involved in the elongation of vascular endothelial cells (ECs) in angiogenesis to identify the activation of the the actin-crosslinking protein Tagln promoter during EC elongation.
Sun Aug 01 00:00:00 EDT 2021
Microtubule destabilization is a critical checkpoint of chemotaxis and transendothelial migration in melanoma cells but not in T cells.
Cell adhesion & migration
Roncato F,Regev O,Yadav SK,Alon R
450-32 was used in In vitro experiments to investigate microtubule turnover in epithelial barriers.
Wed Dec 01 00:00:00 EST 2021
A Microfluidics-Based Screening Tool to Assess the Impact of Blood Plasma Factors on Microvascular Integrity.
Advanced biology
Junaid A,van Duinen V,Stam W,Dólleman S,Yang W,de Rijke Y,Endeman H,van Kooten C,Mashaghi A,de Boer H,van Gils J,Hankemeier T,van Zonneveld AJ
Mon Nov 01 00:00:00 EDT 2021
Multipotent progenitors and hematopoietic stem cells arise independently from hemogenic endothelium in the mouse embryo.
Cell reports
Dignum T,Varnum-Finney B,Srivatsan SR,Dozono S,Waltner O,Heck AM,Ishida T,Nourigat-McKay C,Jackson DL,Rafii S,Trapnell C,Bernstein ID,Hadland B
Tue Sep 14 00:00:00 EDT 2021
SARS-CoV-2 Infects Endothelial Cells In Vivo and In Vitro.
Frontiers in cellular and infection microbiology
Liu F,Han K,Blair R,Kenst K,Qin Z,Upcin B,Wörsdörfer P,Midkiff CC,Mudd J,Belyaeva E,Milligan NS,Rorison TD,Wagner N,Bodem J,Dölken L,Aktas BH,Vander Heide RS,Yin XM,Kolls JK,Roy CJ,Rappaport J,Ergün S,Qin X
450-32 was used in Cell Culture to study whether SARS-CoV-2 causes endotheliopathy by directly infecting endothelial cells to indicate that in addition to pneumocytes, SARS-CoV-2 also directly infects mature vascular endothelial cells in vivo and ex vivo, which may contribute to cardiovascular complications in SARS-CoV-2 infection, including multipleorgan failure.
Thu Jul 29 00:00:00 EDT 2021
Attenuation of apoptotic cell detection triggers thymic regeneration after damage.
Cell reports
Kinsella S,Evandy CA,Cooper K,Iovino L,deRoos PC,Hopwo KS,Granadier DW,Smith CW,Rafii S,Dudakov JA
Tue Oct 05 00:00:00 EDT 2021
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
Blood
He H,Xu P,Zhang X,Liao M,Dong Q,Cong T,Tang B,Yang X,Ye M,Chang Y,Liu W,Wang X,Ju Z,Wang J
Thu Jul 09 00:00:00 EDT 2020
Endothelial MT1-MMP targeting limits intussusceptive angiogenesis and colitis via TSP1/nitric oxide axis.
EMBO molecular medicine
Esteban S,Clemente C,Koziol A,Gonzalo P,Rius C,Martínez F,Linares PM,Chaparro M,Urzainqui A,Andrés V,Seiki M,Gisbert JP,Arroyo AG
Fri Feb 07 00:00:00 EST 2020
Growth differentiation factor 11 promotes differentiation of MSCs into endothelial-like cells for angiogenesis.
Journal of cellular and molecular medicine
Zhang C,Lin Y,Liu Q,He J,Xiang P,Wang D,Hu X,Chen J,Zhu W,Yu H
Sat Aug 01 00:00:00 EDT 2020
Inhibition of retinal neovascularization by a PEDF-derived nonapeptide in newborn mice subjected to oxygen-induced ischemic retinopathy.
Experimental eye research
Sheibani N,Zaitoun IS,Wang S,Darjatmoko SR,Suscha A,Song YS,Sorenson CM,Shifrin V,Albert DM,Melgar-Asensio I,Kandela I,Henkin J
450-32 was used in In vitro experiments to show that PEDF 336 is a potential ROP therapeutic, but is not expected to be beneficial in combination with anti-VEGF.
Mon Jun 01 00:00:00 EDT 2020
12-O-Tetradecanoylphorbol-13-acetate increases cardiomyogenesis through PKC/ERK signaling.
Scientific reports
Radaszkiewicz KA,Beckerová D,Woloszczuková L,Radaszkiewicz TW,Lesáková P,Blanářová OV,Kubala L,Humpolíček P,Pachernik J
Mon Sep 28 00:00:00 EDT 2020
Identification of signature genes associated with therapeutic resistance to anti-VEGF therapy.
Oncotarget
Jaiprasart P,Dogra S,Neelakantan D,Devapatla B,Woo S
450-32 was used in Cell Culture to investigate resistance of ovarian cancer to VEGF-targeted therapies.
Tue Jan 07 00:00:00 EST 2020
CD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling.
Journal of extracellular vesicles
Angioni R,Liboni C,Herkenne S,Sánchez-Rodríguez R,Borile G,Marcuzzi E,Calì B,Muraca M,Viola A
450-32 was used in In vitro experiments to identify novel pathways involved in the crosstalk between endothelial and stromal cell and suggest new therapeutic strategies to target pathological angiogenesis.
Mon Sep 28 00:00:00 EDT 2020
Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner.
Cell reports
Santini MP,Malide D,Hoffman G,Pandey G,D'Escamard V,Nomura-Kitabayashi A,Rovira I,Kataoka H,Ochando J,Harvey RP,Finkel T,Kovacic JC
450-32 was used in In vitro experiments to support a context-dependent yin-yang" biology of tissue-resident mesenchymal progenitor cells
Tue Jan 14 00:00:00 EST 2020
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Nature communications
Lechertier T,Reynolds LE,Kim H,Pedrosa AR,Gómez-Escudero J,Muñoz-Félix JM,Batista S,Dukinfield M,Demircioglu F,Wong PP,Matchett KP,Henderson NC,D'Amico G,Parsons M,Harwood C,Meier P,Hodivala-Dilke KM
Thu Jun 04 00:00:00 EDT 2020
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth.
Nature communications
Lechertier T,Reynolds LE,Kim H,Pedrosa AR,Gómez-Escudero J,Muñoz-Félix JM,Batista S,Dukinfield M,Demircioglu F,Wong PP,Matchett KP,Henderson NC,D'Amico G,Parsons M,Harwood C,Meier P,Hodivala-Dilke KM
Thu Jun 04 00:00:00 EDT 2020
Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth.
Nature communications
Schiffmann LM,Werthenbach JP,Heintges-Kleinhofer F,Seeger JM,Fritsch M,Günther SD,Willenborg S,Brodesser S,Lucas C,Jüngst C,Albert MC,Schorn F,Witt A,Moraes CT,Bruns CJ,Pasparakis M,Krönke M,Eming SA,Coutelle O,Kashkar H
Tue Jul 21 00:00:00 EDT 2020
Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
EMBO molecular medicine
Uribesalgo I,Hoffmann D,Zhang Y,Kavirayani A,Lazovic J,Berta J,Novatchkova M,Pai TP,Wimmer RA,László V,Schramek D,Karim R,Tortola L,Deswal S,Haas L,Zuber J,Szűcs M,Kuba K,Dome B,Cao Y,Haubner BJ,Penninger JM
Thu Aug 01 00:00:00 EDT 2019
Aging induces cardiac mesenchymal stromal cell senescence and promotes endothelial cell fate of the CD90 + subset.
Aging cell
Martini H,Iacovoni JS,Maggiorani D,Dutaur M,Marsal DJ,Roncalli J,Itier R,Dambrin C,Pizzinat N,Mialet-Perez J,Cussac D,Parini A,Lefevre L,Douin-Echinard V
Tue Oct 01 00:00:00 EDT 2019
Perfused 3D angiogenic sprouting in a high-throughput in vitro platform.
Angiogenesis
van Duinen V,Zhu D,Ramakers C,van Zonneveld AJ,Vulto P,Hankemeier T
450-32 was used in Cell Culture to propose an in vitro platform that integrates both perfusion and the generation of stable biomolecular gradients and demonstrate its potential to study more physiologically relevant angiogenic sprouting and microvascular stabilization.
Fri Feb 01 00:00:00 EST 2019
Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation.
Angiogenesis
Darden J,Payne LB,Zhao H,Chappell JC
450-32 was used in Cell Culture to illuminate how angiogenic signaling pathways intersect to regulate pericyte migration and investment.
Fri Feb 01 00:00:00 EST 2019
Myc-dependent endothelial proliferation is controlled by phosphotyrosine 1212 in VEGF receptor-2.
EMBO reports
Testini C,Smith RO,Jin Y,Martinsson P,Sun Y,Hedlund M,Sáinz-Jaspeado M,Shibuya M,Hellström M,Claesson-Welsh L
Tue Nov 05 00:00:00 EST 2019
Role of CXCR2 in the Ac-PGP-Induced Mobilization of Circulating Angiogenic Cells and its Therapeutic Implications.
Stem cells translational medicine
Kwon YW,Lee SJ,Heo SC,Lee TW,Park GT,Yoon JW,Kim SC,Shin HJ,Lee SC,Kim JH
Fri Mar 01 00:00:00 EST 2019
Inhibition of host NOX1 blocks tumor growth and enhances checkpoint inhibitor-based immunotherapy.
Life science alliance
Stalin J,Garrido-Urbani S,Heitz F,Szyndralewiez C,Jemelin S,Coquoz O,Ruegg C,Imhof BA
450-32 was used in Cell Culture to study the efficacy of NOX1 inhibition by GKT771 as an anticancer strategy, particularly in combination with checkpoint inhibition.
Thu Aug 01 00:00:00 EDT 2019
High mitogenic stimulation arrests angiogenesis.
Nature communications
Pontes-Quero S,Fernández-Chacón M,Luo W,Lunella FF,Casquero-Garcia V,Garcia-Gonzalez I,Hermoso A,Rocha SF,Bansal M,Benedito R
Wed May 01 00:00:00 EDT 2019
Structural basis for delta cell paracrine regulation in pancreatic islets.
Nature communications
Arrojo E Drigo R,Jacob S,García-Prieto CF,Zheng X,Fukuda M,Nhu HTT,Stelmashenko O,Peçanha FLM,Rodriguez-Diaz R,Bushong E,Deerinck T,Phan S,Ali Y,Leibiger I,Chua M,Boudier T,Song SH,Graf M,Augustine GJ,Ellisman MH,Berggren PO
450-32 was used in In vitro experiments to study the structural basis underlying delta cell paracrine regulation of beta cell and alpha cell secretory activity.
Fri Aug 16 00:00:00 EDT 2019
Structural basis for delta cell paracrine regulation in pancreatic islets.
Nature communications
Arrojo E Drigo R,Jacob S,García-Prieto CF,Zheng X,Fukuda M,Nhu HTT,Stelmashenko O,Peçanha FLM,Rodriguez-Diaz R,Bushong E,Deerinck T,Phan S,Ali Y,Leibiger I,Chua M,Boudier T,Song SH,Graf M,Augustine GJ,Ellisman MH,Berggren PO
450-32 was used in In vitro experiments to study the structural basis underlying delta cell paracrine regulation of beta cell and alpha cell secretory activity.
Fri Aug 16 00:00:00 EDT 2019
Vasculogenic properties of adventitial Sca-1+CD45+ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis.
Scientific reports
Toledo-Flores D,Williamson A,Schwarz N,Fernando S,Dimasi C,Witt TA,Nguyen TM,Puranik AS,Chue CD,Delacroix S,Spoon DB,Bonder CS,Bursill CA,Di Bartolo BA,Nicholls SJ,Simari RD,Psaltis PJ
Mon May 13 00:00:00 EDT 2019
1,25(OH)2D3 regulates the proangiogenic activity of pericyte through VDR-mediated modulation of VEGF production and signaling of VEGF and PDGF receptors.
FASEB bioAdvances
Jamali N,Song YS,Sorenson CM,Sheibani N
450-32 was used in In vitro experiments to determine the impact of 1,25(OH)2D3 on retinal pericytes prepared from wild type and VDR-deficient mice.
Mon Jul 01 00:00:00 EDT 2019
Anti-inflammatory and vasculogenic conditioning of peripheral blood mononuclear cells reinforces their therapeutic potential for radiation-injured salivary glands.
Stem cell research & therapy
I T,Sumita Y,Yoshida T,Honma R,Iwatake M,Raudales JLM,Shizuno T,Kuroshima S,Masuda H,Seki M,Tran SD,Asahara T,Asahina I
450-32 was used in Cell Culture to investigate methods conditioning peripheral blood mononuclear cells to regenerate salivary gland following head and neck cancer treatment.
Thu Oct 17 00:00:00 EDT 2019
Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function.
Cell
Shah PT,Stratton JA,Stykel MG,Abbasi S,Sharma S,Mayr KA,Koblinger K,Whelan PJ,Biernaskie J
Thu May 03 00:00:00 EDT 2018
Single-Cell Transcriptomics and Fate Mapping of Ependymal Cells Reveals an Absence of Neural Stem Cell Function.
Cell
Shah PT,Stratton JA,Stykel MG,Abbasi S,Sharma S,Mayr KA,Koblinger K,Whelan PJ,Biernaskie J
Thu May 03 00:00:00 EDT 2018
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production.
Cell
Longchamp A,Mirabella T,Arduini A,MacArthur MR,Das A,Treviño-Villarreal JH,Hine C,Ben-Sahra I,Knudsen NH,Brace LE,Reynolds J,Mejia P,Tao M,Sharma G,Wang R,Corpataux JM,Haefliger JA,Ahn KH,Lee CH,Manning BD,Sinclair DA,Chen CS,Ozaki CK,Mitchell JR
Thu Mar 22 00:00:00 EDT 2018
TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer.
Cancer cell
de Mingo Pulido Á,Gardner A,Hiebler S,Soliman H,Rugo HS,Krummel MF,Coussens LM,Ruffell B
Mon Jan 08 00:00:00 EST 2018
The TGFβ pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.
Developmental biology
Lempereur A,Canto PY,Richard C,Martin S,Thalgott J,Raymond K,Lebrin F,Drevon C,Jaffredo T
450-32 was used in Cell Culture to analyse the BMP/TGFß signaling pathway members in the endothelial and hematopoietic compartments of the aorta at pre-hematopoietic and hematopoietic stages.
Thu Feb 15 00:00:00 EST 2018
The TGFβ pathway is a key player for the endothelial-to-hematopoietic transition in the embryonic aorta.
Developmental biology
Lempereur A,Canto PY,Richard C,Martin S,Thalgott J,Raymond K,Lebrin F,Drevon C,Jaffredo T
450-32 was used in Cell Culture to analyse the BMP/TGFß signaling pathway members in the endothelial and hematopoietic compartments of the aorta at pre-hematopoietic and hematopoietic stages.
Thu Feb 15 00:00:00 EST 2018
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.
Nature communications
Mira E,Carmona-Rodríguez L,Pérez-Villamil B,Casas J,Fernández-Aceñero MJ,Martínez-Rey D,Martín-González P,Heras-Murillo I,Paz-Cabezas M,Tardáguila M,Oury TD,Martín-Puig S,Lacalle RA,Fabriás G,Díaz-Rubio E,Mañes S
Thu Feb 08 00:00:00 EST 2018
SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.
Nature communications
Mira E,Carmona-Rodríguez L,Pérez-Villamil B,Casas J,Fernández-Aceñero MJ,Martínez-Rey D,Martín-González P,Heras-Murillo I,Paz-Cabezas M,Tardáguila M,Oury TD,Martín-Puig S,Lacalle RA,Fabriás G,Díaz-Rubio E,Mañes S
Thu Feb 08 00:00:00 EST 2018
In Vitro Differentiation of Gata2 and Ly6a Reporter Embryonic Stem Cells Corresponds to In Vivo Waves of Hematopoietic Cell Generation.
Stem cell reports
Kauts ML,Rodriguez-Seoane C,Kaimakis P,Mendes SC,Cortés-Lavaud X,Hill U,Dzierzak E
Tue Jan 09 00:00:00 EST 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.
Nature communications
Ishihara J,Ishihara A,Fukunaga K,Sasaki K,White MJV,Briquez PS,Hubbell JA
Mon Jun 04 00:00:00 EDT 2018
MPDZ promotes DLL4-induced Notch signaling during angiogenesis.
eLife
Tetzlaff F,Adam MG,Feldner A,Moll I,Menuchin A,Rodriguez-Vita J,Sprinzak D,Fischer A
450-32 was used in Cell Culture to identify multiple PDZ domain protein as a novel modulator of Notch signaling by controlling ligand recruitment to adherens junctions.
Thu Apr 05 00:00:00 EDT 2018
Characterization of multi-cellular dynamics of angiogenesis and vascular remodelling by intravital imaging of the wounded mouse cornea.
Scientific reports
Wang Y,Jin Y,Laviña B,Jakobsson L
Fri Jul 13 00:00:00 EDT 2018
LMO2 is required for TAL1 DNA binding activity and initiation of definitive haematopoiesis at the haemangioblast stage.
Nucleic acids research
Stanulovic VS,Cauchy P,Assi SA,Hoogenkamp M
450-32 was used in In vitro experiments to show that Lmo2-/- mouse embryonic stem cells differentiated to Flk-1+ haemangioblasts, but less efficiently to haemogenic endothelium.
Fri Sep 29 00:00:00 EDT 2017
Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain.
Neuron
Voronova A,Yuzwa SA,Wang BS,Zahr S,Syal C,Wang J,Kaplan DR,Miller FD
Wed May 03 00:00:00 EDT 2017
Wilms tumor protein-dependent transcription of VEGF receptor 2 and hypoxia regulate expression of the testis-promoting gene Sox9 in murine embryonic gonads.
The Journal of biological chemistry
Kirschner KM,Sciesielski LK,Krueger K,Scholz H
Fri Dec 08 00:00:00 EST 2017
96 perfusable blood vessels to study vascular permeability in vitro.
Scientific reports
van Duinen V,van den Heuvel A,Trietsch SJ,Lanz HL,van Gils JM,van Zonneveld AJ,Vulto P,Hankemeier T
Fri Dec 22 00:00:00 EST 2017
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Proceedings of the National Academy of Sciences of the United States of America
Wentink MQ,Hackeng TM,Tabruyn SP,Puijk WC,Schwamborn K,Altschuh D,Meloen RH,Schuurman T,Griffioen AW,Timmerman P
Tue Nov 01 00:00:00 EDT 2016
Targeted vaccination against the bevacizumab binding site on VEGF using 3D-structured peptides elicits efficient antitumor activity.
Proceedings of the National Academy of Sciences of the United States of America
Wentink MQ,Hackeng TM,Tabruyn SP,Puijk WC,Schwamborn K,Altschuh D,Meloen RH,Schuurman T,Griffioen AW,Timmerman P
Tue Nov 01 00:00:00 EDT 2016
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread.
Nature communications
Li X,Padhan N,Sjöström EO,Roche FP,Testini C,Honkura N,Sáinz-Jaspeado M,Gordon E,Bentley K,Philippides A,Tolmachev V,Dejana E,Stan RV,Vestweber D,Ballmer-Hofer K,Betsholtz C,Pietras K,Jansson L,Claesson-Welsh L
Wed Mar 23 00:00:00 EDT 2016
EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.
Scientific reports
Chen II,Caprioli A,Ohnuki H,Kwak H,Porcher C,Tosato G
450-32 was used in Cell Culture to identify EphrinB2 as an essential regulator of adult haematopoiesis but not generation of endothelial cells.
Thu Jun 02 00:00:00 EDT 2016
EphrinB2 regulates the emergence of a hemogenic endothelium from the aorta.
Scientific reports
Chen II,Caprioli A,Ohnuki H,Kwak H,Porcher C,Tosato G
450-32 was used in Cell Culture to identify EphrinB2 as an essential regulator of adult haematopoiesis but not generation of endothelial cells.
Thu Jun 02 00:00:00 EDT 2016
Role of metabolic modulator Bet-CA in altering mitochondrial hyperpolarization to suppress cancer associated angiogenesis and metastasis.
Scientific reports
Saha S,Ghosh M,Dutta SK
Tue Mar 22 00:00:00 EDT 2016
NAADP-Dependent Ca(2+) Signaling Controls Melanoma Progression, Metastatic Dissemination and Neoangiogenesis.
Scientific reports
Favia A,Pafumi I,Desideri M,Padula F,Montesano C,Passeri D,Nicoletti C,Orlandi A,Del Bufalo D,Sergi M,Ziparo E,Palombi F,Filippini A
Wed Jan 06 00:00:00 EST 2016
Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.
Blood
Jang IH,Lu YF,Zhao L,Wenzel PL,Kume T,Datta SM,Arora N,Guiu J,Lagha M,Kim PG,Do EK,Kim JH,Schlaeger TM,Zon LI,Bigas A,Burns CE,Daley GQ
Thu Feb 26 00:00:00 EST 2015
Identification and characterization of VEGF-A-responsive neutrophils expressing CD49d, VEGFR1, and CXCR4 in mice and humans.
Blood
Massena S,Christoffersson G,Vågesjö E,Seignez C,Gustafsson K,Binet F,Herrera Hidalgo C,Giraud A,Lomei J,Weström S,Shibuya M,Claesson-Welsh L,Gerwins P,Welsh M,Kreuger J,Phillipson M
Thu Oct 22 00:00:00 EDT 2015
Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cells.
The Journal of clinical investigation
Hadland BK,Varnum-Finney B,Poulos MG,Moon RT,Butler JM,Rafii S,Bernstein ID
Fri May 01 00:00:00 EDT 2015
IL-17A, but not IL-17F, is indispensable for airway vascular remodeling induced by exaggerated Th17 cell responses in prolonged ovalbumin-challenged mice.
Journal of immunology (Baltimore, Md. : 1950)
Lu S,Li H,Gao R,Gao X,Xu F,Wang Q,Lu G,Xia D,Zhou J
Wed Apr 15 00:00:00 EDT 2015
Developmental-stage-dependent transcriptional response to leukaemic oncogene expression.
Nature communications
Regha K,Assi SA,Tsoulaki O,Gilmour J,Lacaud G,Bonifer C
Thu May 28 00:00:00 EDT 2015
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Nature communications
Aspalter IM,Gordon E,Dubrac A,Ragab A,Narloch J,Vizán P,Geudens I,Collins RT,Franco CA,Abrahams CL,Thurston G,Fruttiger M,Rosewell I,Eichmann A,Gerhardt H
Wed Jun 17 00:00:00 EDT 2015
Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch.
Nature communications
Aspalter IM,Gordon E,Dubrac A,Ragab A,Narloch J,Vizán P,Geudens I,Collins RT,Franco CA,Abrahams CL,Thurston G,Fruttiger M,Rosewell I,Eichmann A,Gerhardt H
Wed Jun 17 00:00:00 EDT 2015
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis.
Nature communications
Serra H,Chivite I,Angulo-Urarte A,Soler A,Sutherland JD,Arruabarrena-Aristorena A,Ragab A,Lim R,Malumbres M,Fruttiger M,Potente M,Serrano M,Fabra À,Viñals F,Casanovas O,Pandolfi PP,Bigas A,Carracedo A,Gerhardt H,Graupera M
Fri Jul 31 00:00:00 EDT 2015
Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.
Scientific reports
Liu Y,Yang X,Jing Y,Zhang S,Zong C,Jiang J,Sun K,Li R,Gao L,Zhao X,Wu D,Shi Y,Han Z,Wei L
Tue Dec 08 00:00:00 EST 2015
Contribution and Mobilization of Mesenchymal Stem Cells in a mouse model of carbon tetrachloride-induced liver fibrosis.
Scientific reports
Liu Y,Yang X,Jing Y,Zhang S,Zong C,Jiang J,Sun K,Li R,Gao L,Zhao X,Wu D,Shi Y,Han Z,Wei L
Tue Dec 08 00:00:00 EST 2015
SLM produced porous titanium implant improvements for enhanced vascularization and osteoblast seeding.
International journal of molecular sciences
Matena J,Petersen S,Gieseke M,Kampmann A,Teske M,Beyerbach M,Murua Escobar H,Haferkamp H,Gellrich NC,Nolte I
450-32 was used in Cell Culture to evaluate the effectiveness of Selective Laser Melting on vascularization and osteoblast seeding.
Thu Apr 02 00:00:00 EDT 2015
Transcriptional activation of hypoxia-inducible factor-1 (HIF-1) in myeloid cells promotes angiogenesis through VEGF and S100A8.
Proceedings of the National Academy of Sciences of the United States of America
Ahn GO,Seita J,Hong BJ,Kim YE,Bok S,Lee CJ,Kim KS,Lee JC,Leeper NJ,Cooke JP,Kim HJ,Kim IH,Weissman IL,Brown JM
Tue Feb 18 00:00:00 EST 2014
Long-lasting fibrin matrices ensure stable and functional angiogenesis by highly tunable, sustained delivery of recombinant VEGF164.
Proceedings of the National Academy of Sciences of the United States of America
Sacchi V,Mittermayr R,Hartinger J,Martino MM,Lorentz KM,Wolbank S,Hofmann A,Largo RA,Marschall JS,Groppa E,Gianni-Barrera R,Ehrbar M,Hubbell JA,Redl H,Banfi A
Tue May 13 00:00:00 EDT 2014
Pcgf6, a polycomb group protein, regulates mesodermal lineage differentiation in murine ESCs and functions in iPS reprogramming.
Stem cells (Dayton, Ohio)
Zdzieblo D,Li X,Lin Q,Zenke M,Illich DJ,Becker M,Müller AM
Mon Dec 01 00:00:00 EST 2014
Protein-tyrosine phosphatase 4A3 (PTP4A3) promotes vascular endothelial growth factor signaling and enables endothelial cell motility.
The Journal of biological chemistry
Zimmerman MW,McQueeney KE,Isenberg JS,Pitt BR,Wasserloos KA,Homanics GE,Lazo JS
Fri Feb 28 00:00:00 EST 2014
Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
Cell death & disease
Yao WT,Wu JF,Yu GY,Wang R,Wang K,Li LH,Chen P,Jiang YN,Cheng H,Lee HW,Yu J,Qi H,Yu XJ,Wang P,Chu YW,Yang M,Hua ZC,Ying HQ,Hoffman RM,Jeong LS,Jia LJ
Thu Feb 13 00:00:00 EST 2014
A novel tissue model for angiogenesis: evaluation of inhibitors or promoters in tissue level.
Scientific reports
Dai B,Zhang Y,Zhan Y,Zhang D,Wang N,He L
Wed Jan 15 00:00:00 EST 2014
Endothelial lineage differentiation from induced pluripotent stem cells is regulated by microRNA-21 and transforming growth factor β2 (TGF-β2) pathways.
The Journal of biological chemistry
Di Bernardini E,Campagnolo P,Margariti A,Zampetaki A,Karamariti E,Hu Y,Xu Q
Fri Feb 07 00:00:00 EST 2014
Deletion of Fgfr1 in osteoblasts enhances mobilization of EPCs into peripheral blood in a mouse endotoxemia model.
International journal of biological sciences
Zhang Y,Su N,Luo F,Wen X,Tang Y,Yang J,Chen S,Jiang W,Du X,Chen L
Fri May 15 00:00:00 EDT 2015
Genome-wide approaches reveal functional vascular endothelial growth factor (VEGF)-inducible nuclear factor of activated T cells (NFAT) c1 binding to angiogenesis-related genes in the endothelium.
The Journal of biological chemistry
Suehiro J,Kanki Y,Makihara C,Schadler K,Miura M,Manabe Y,Aburatani H,Kodama T,Minami T
Fri Oct 17 00:00:00 EDT 2014
WT1 regulates murine hematopoiesis via maintenance of VEGF isoform ratio.
Blood
Cunningham TJ,Palumbo I,Grosso M,Slater N,Miles CG
Thu Jul 11 00:00:00 EDT 2013
Nogo-A is a negative regulator of CNS angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America
Wälchli T,Pernet V,Weinmann O,Shiu JY,Guzik-Kornacka A,Decrey G,Yüksel D,Schneider H,Vogel J,Ingber DE,Vogel V,Frei K,Schwab ME
Tue May 21 00:00:00 EDT 2013
Mesenchymal stem cells are mobilized from the bone marrow during inflammation.
Frontiers in immunology
Koning JJ,Kooij G,de Vries HE,Nolte MA,Mebius RE
Wed Mar 06 00:00:00 EST 2013
The role of IL-1β in the early tumor cell-induced angiogenic response.
Journal of immunology (Baltimore, Md. : 1950)
Carmi Y,Dotan S,Rider P,Kaplanov I,White MR,Baron R,Abutbul S,Huszar M,Dinarello CA,Apte RN,Voronov E
Mon Apr 01 00:00:00 EDT 2013
Sox17 is indispensable for acquisition and maintenance of arterial identity.
Nature communications
Corada M,Orsenigo F,Morini MF,Pitulescu ME,Bhat G,Nyqvist D,Breviario F,Conti V,Briot A,Iruela-Arispe ML,Adams RH,Dejana E
Thu Jun 12 00:00:00 EDT 2014
Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivo.
The Journal of biological chemistry
Tugues S,Honjo S,König C,Padhan N,Kroon J,Gualandi L,Li X,Barkefors I,Thijssen VL,Griffioen AW,Claesson-Welsh L
Fri Jun 28 00:00:00 EDT 2013
Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-β1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivo.
The Journal of biological chemistry
Tugues S,Honjo S,König C,Padhan N,Kroon J,Gualandi L,Li X,Barkefors I,Thijssen VL,Griffioen AW,Claesson-Welsh L
Fri Jun 28 00:00:00 EDT 2013
The transcription factors Tbx18 and Wt1 control the epicardial epithelial-mesenchymal transition through bi-directional regulation of Slug in murine primary epicardial cells.
PloS one
Takeichi M,Nimura K,Mori M,Nakagami H,Kaneda Y
Thu Aug 29 00:00:00 EDT 2013
Scl represses cardiomyogenesis in prospective hemogenic endothelium and endocardium.
Cell
Van Handel B,Montel-Hagen A,Sasidharan R,Nakano H,Ferrari R,Boogerd CJ,Schredelseker J,Wang Y,Hunter S,Org T,Zhou J,Li X,Pellegrini M,Chen JN,Orkin SH,Kurdistani SK,Evans SM,Nakano A,Mikkola HK
Fri Aug 03 00:00:00 EDT 2012
Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures.
Nature methods
Fluri DA,Tonge PD,Song H,Baptista RP,Shakiba N,Shukla S,Clarke G,Nagy A,Zandstra PW
Sun Mar 25 00:00:00 EDT 2012
VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice.
Blood
Pitchford SC,Lodie T,Rankin SM
Thu Oct 04 00:00:00 EDT 2012
VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue.
Blood
Christoffersson G,Vågesjö E,Vandooren J,Lidén M,Massena S,Reinert RB,Brissova M,Powers AC,Opdenakker G,Phillipson M
Thu Nov 29 00:00:00 EST 2012
Dual actions of Meis1 inhibit erythroid progenitor development and sustain general hematopoietic cell proliferation.
Blood
Cai M,Langer EM,Gill JG,Satpathy AT,Albring JC,KC W,Murphy TL,Murphy KM
Thu Jul 12 00:00:00 EDT 2012
Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease.
The Journal of clinical investigation
Argaw AT,Asp L,Zhang J,Navrazhina K,Pham T,Mariani JN,Mahase S,Dutta DJ,Seto J,Kramer EG,Ferrara N,Sofroniew MV,John GR
Sun Jul 01 00:00:00 EDT 2012
VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.
The Journal of experimental medicine
Sun Z,Li X,Massena S,Kutschera S,Padhan N,Gualandi L,Sundvold-Gjerstad V,Gustafsson K,Choy WW,Zang G,Quach M,Jansson L,Phillipson M,Abid MR,Spurkland A,Claesson-Welsh L
Mon Jul 02 00:00:00 EDT 2012
VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.
The Journal of experimental medicine
Sun Z,Li X,Massena S,Kutschera S,Padhan N,Gualandi L,Sundvold-Gjerstad V,Gustafsson K,Choy WW,Zang G,Quach M,Jansson L,Phillipson M,Abid MR,Spurkland A,Claesson-Welsh L
Mon Jul 02 00:00:00 EDT 2012
Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems.
Cell death and differentiation
Cesca F,Yabe A,Spencer-Dene B,Scholz-Starke J,Medrihan L,Maden CH,Gerhardt H,Orriss IR,Baldelli P,Al-Qatari M,Koltzenburg M,Adams RH,Benfenati F,Schiavo G
450-32 was used in Cell Culture to indicate that Kidins220 mediates the integration of several growth factor receptor pathways during development.
Wed Feb 01 00:00:00 EST 2012
Tumor-expressed inducible nitric oxide synthase controls induction of functional myeloid-derived suppressor cells through modulation of vascular endothelial growth factor release.
Journal of immunology (Baltimore, Md. : 1950)
Jayaraman P,Parikh F,Lopez-Rivera E,Hailemichael Y,Clark A,Ma G,Cannan D,Ramacher M,Kato M,Overwijk WW,Chen SH,Umansky VY,Sikora AG
Fri Jun 01 00:00:00 EDT 2012
Transgenesis-mediated reproductive dysfunction and tumorigenesis: effects of immunological neutralization.
PloS one
Sachdeva R,Bhardwaj N,Huhtaniemi I,Aggrawal U,Jain SK,Zaidi R,Singh O,Pal R
Tue May 28 00:00:00 EDT 2013
Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.
PloS one
Yamaguchi T,Hamanaka S,Kamiya A,Okabe M,Kawarai M,Wakiyama Y,Umino A,Hayama T,Sato H,Lee YS,Kato-Itoh M,Masaki H,Kobayashi T,Yamazaki S,Nakauchi H
Wed Jan 16 00:00:00 EST 2013
Development of an all-in-one inducible lentiviral vector for gene specific analysis of reprogramming.
PloS one
Yamaguchi T,Hamanaka S,Kamiya A,Okabe M,Kawarai M,Wakiyama Y,Umino A,Hayama T,Sato H,Lee YS,Kato-Itoh M,Masaki H,Kobayashi T,Yamazaki S,Nakauchi H
Wed Jan 16 00:00:00 EST 2013
Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells.
Blood
Oshima M,Endoh M,Endo TA,Toyoda T,Nakajima-Takagi Y,Sugiyama F,Koseki H,Kyba M,Iwama A,Osawa M
Thu Apr 14 00:00:00 EDT 2011
Modulation of TGF-β signaling by endoglin in murine hemangioblast development and primitive hematopoiesis.
Blood
Zhang L,Magli A,Catanese J,Xu Z,Kyba M,Perlingeiro RC
Thu Jul 07 00:00:00 EDT 2011
Adult human circulating CD34⁻Lin⁻CD45⁻CD133⁻ cells can differentiate into hematopoietic and endothelial cells.
Blood
Ciraci E,Della Bella S,Salvucci O,Rofani C,Segarra M,Bason C,Molinari A,Maric D,Tosato G,Berardi AC
Thu Aug 25 00:00:00 EDT 2011
Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region.
The Journal of experimental medicine
Rybtsov S,Sobiesiak M,Taoudi S,Souilhol C,Senserrich J,Liakhovitskaia A,Ivanovs A,Frampton J,Zhao S,Medvinsky A
Mon Jun 06 00:00:00 EDT 2011
Serotonin reverts age-related capillarization and failure of regeneration in the liver through a VEGF-dependent pathway.
Proceedings of the National Academy of Sciences of the United States of America
Furrer K,Rickenbacher A,Tian Y,Jochum W,Bittermann AG,Käch A,Humar B,Graf R,Moritz W,Clavien PA
Tue Feb 15 00:00:00 EST 2011
VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels.
Development (Cambridge, England)
Cariboni A,Davidson K,Dozio E,Memi F,Schwarz Q,Stossi F,Parnavelas JG,Ruhrberg C
Thu Sep 01 00:00:00 EDT 2011
Heparan sulfate regulates VEGF165- and VEGF121-mediated vascular hyperpermeability.
The Journal of biological chemistry
Xu D,Fuster MM,Lawrence R,Esko JD
Fri Jan 07 00:00:00 EST 2011
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.
PloS one
Garrido-Urbani S,Jemelin S,Deffert C,Carnesecchi S,Basset O,Szyndralewiez C,Heitz F,Page P,Montet X,Michalik L,Arbiser J,Rüegg C,Krause KH,Imhof BA
Mon Feb 07 00:00:00 EST 2011
Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness.
The Journal of biological chemistry
Hu J,Mukhopadhyay A,Craig AW
Fri Jan 21 00:00:00 EST 2011
PlGF repairs myocardial ischemia through mechanisms of angiogenesis, cardioprotection and recruitment of myo-angiogenic competent marrow progenitors.
PloS one
Iwasaki H,Kawamoto A,Tjwa M,Horii M,Hayashi S,Oyamada A,Matsumoto T,Suehiro S,Carmeliet P,Asahara T
Fri Apr 13 00:00:00 EDT 2012
Use of the mouse aortic ring assay to study angiogenesis.
Nature protocols
Baker M,Robinson SD,Lechertier T,Barber PR,Tavora B,D'Amico G,Jones DT,Vojnovic B,Hodivala-Dilke K
Thu Dec 22 00:00:00 EST 2011
Mesenchymal stem cells exhibit firm adhesion, crawling, spreading and transmigration across aortic endothelial cells: effects of chemokines and shear.
PloS one
Chamberlain G,Smith H,Rainger GE,Middleton J
Thu Jan 26 00:00:00 EST 2012
The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells.
BMC immunology
Sprague L,Muccioli M,Pate M,Meles E,McGinty J,Nandigam H,Venkatesh AK,Gu MY,Mansfield K,Rutowski A,Omosebi O,Courreges MC,Benencia F
Mon Jun 06 00:00:00 EDT 2011
The interplay between surfaces and soluble factors define the immunologic and angiogenic properties of myeloid dendritic cells.
BMC immunology
Sprague L,Muccioli M,Pate M,Meles E,McGinty J,Nandigam H,Venkatesh AK,Gu MY,Mansfield K,Rutowski A,Omosebi O,Courreges MC,Benencia F
Mon Jun 06 00:00:00 EDT 2011
Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.
Blood
Ohki M,Ohki Y,Ishihara M,Nishida C,Tashiro Y,Akiyama H,Komiyama H,Lund LR,Nitta A,Yamada K,Zhu Z,Ogawa H,Yagita H,Okumura K,Nakauchi H,Werb Z,Heissig B,Hattori K
Thu May 27 00:00:00 EDT 2010
Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia.
Blood
Kidoya H,Naito H,Takakura N
Thu Apr 15 00:00:00 EDT 2010
Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment.
Proceedings of the National Academy of Sciences of the United States of America
Ahn GO,Tseng D,Liao CH,Dorie MJ,Czechowicz A,Brown JM
Tue May 04 00:00:00 EDT 2010
Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment.
Proceedings of the National Academy of Sciences of the United States of America
Ahn GO,Tseng D,Liao CH,Dorie MJ,Czechowicz A,Brown JM
Tue May 04 00:00:00 EDT 2010
Cell delivery of Met docking site peptides inhibit angiogenesis and vascular tumor growth.
Oncogene
Cantelmo AR,Cammarota R,Noonan DM,Focaccetti C,Comoglio PM,Prat M,Albini A
Thu Sep 23 00:00:00 EDT 2010
Development and function of myeloid-derived suppressor cells generated from mouse embryonic and hematopoietic stem cells.
Stem cells (Dayton, Ohio)
Zhou Z,French DL,Ma G,Eisenstein S,Chen Y,Divino CM,Keller G,Chen SH,Pan PY
Wed Mar 31 00:00:00 EDT 2010
Osteoblasts are a major source of inflammatory cytokines in the tumor microenvironment of bone metastatic breast cancer.
Journal of cellular biochemistry
Bussard KM,Venzon DJ,Mastro AM
Wed Dec 01 00:00:00 EST 2010
The regulatory mechanism of extracellular Hsp90{alpha} on matrix metalloproteinase-2 processing and tumor angiogenesis.
The Journal of biological chemistry
Song X,Wang X,Zhuo W,Shi H,Feng D,Sun Y,Liang Y,Fu Y,Zhou D,Luo Y
Fri Dec 17 00:00:00 EST 2010
Syndecan-1 regulates alphavbeta3 and alphavbeta5 integrin activation during angiogenesis and is blocked by synstatin, a novel peptide inhibitor.
The Journal of experimental medicine
Beauvais DM,Ell BJ,McWhorter AR,Rapraeger AC
Mon Mar 16 00:00:00 EDT 2009
VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown.
Proceedings of the National Academy of Sciences of the United States of America
Argaw AT,Gurfein BT,Zhang Y,Zameer A,John GR
Tue Feb 10 00:00:00 EST 2009
CXCR2 mediates the recruitment of endothelial progenitor cells during allergic airways remodeling.
Stem cells (Dayton, Ohio)
Jones CP,Pitchford SC,Lloyd CM,Rankin SM
Tue Dec 01 00:00:00 EST 2009
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1.
Genome medicine
Larsson E,Fredlund Fuchs P,Heldin J,Barkefors I,Bondjers C,Genové G,Arrondel C,Gerwins P,Kurschat C,Schermer B,Benzing T,Harvey SJ,Kreuger J,Lindahl P
Mon Nov 16 00:00:00 EST 2009
Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases.
Neural development
Vivancos V,Chen P,Spassky N,Qian D,Dabdoub A,Kelley M,Studer M,Guthrie S
Wed Feb 11 00:00:00 EST 2009
A role for VEGF as a negative regulator of pericyte function and vessel maturation.
Nature
Greenberg JI,Shields DJ,Barillas SG,Acevedo LM,Murphy E,Huang J,Scheppke L,Stockmann C,Johnson RS,Angle N,Cheresh DA
Thu Dec 11 00:00:00 EST 2008
Angiostatic activity of the antitumor cytokine interleukin-21.
Blood
Castermans K,Tabruyn SP,Zeng R,van Beijnum JR,Eppolito C,Leonard WJ,Shrikant PA,Griffioen AW
Mon Dec 15 00:00:00 EST 2008
VE-PTP maintains the endothelial barrier via plakoglobin and becomes dissociated from VE-cadherin by leukocytes and by VEGF.
The Journal of experimental medicine
Nottebaum AF,Cagna G,Winderlich M,Gamp AC,Linnepe R,Polaschegg C,Filippova K,Lyck R,Engelhardt B,Kamenyeva O,Bixel MG,Butz S,Vestweber D
Mon Nov 24 00:00:00 EST 2008
Reprogrammed mouse fibroblasts differentiate into cells of the cardiovascular and hematopoietic lineages.
Stem cells (Dayton, Ohio)
Schenke-Layland K,Rhodes KE,Angelis E,Butylkova Y,Heydarkhan-Hagvall S,Gekas C,Zhang R,Goldhaber JI,Mikkola HK,Plath K,MacLellan WR
Sun Jun 01 00:00:00 EDT 2008
Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation.
Cancer biology & therapy
Benencia F,Courrèges MC,Fraser NW,Coukos G
450-32 was used in Enzyme-linked immunosorbent assay to show how oncolytic HSV-1716 generates vaccination effects and that that oncolytic therapy with HSV-1716 facilitates antitumor immune responses.
Fri Aug 01 00:00:00 EDT 2008
Leukotriene B4, an activation product of mast cells, is a chemoattractant for their progenitors.
The Journal of experimental medicine
Weller CL,Collington SJ,Brown JK,Miller HR,Al-Kashi A,Clark P,Jose PJ,Hartnell A,Williams TJ
Mon Jun 20 00:00:00 EDT 2005
A role for thrombopoietin in hemangioblast development.
Stem cells (Dayton, Ohio)
Perlingeiro RC,Kyba M,Bodie S,Daley GQ
Fri Feb 27 00:00:00 EST 2004