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Product Details
BMS359
Product Specifications
Species
Mouse
Expression System
E. coli
Amino acid sequence
Mouse VEGF-165 recombinant protein is homodimeric containing two 165 amino acid polypeptide chains
Molecular weight
39 kDa
Class
Recombinant
Type
Protein
Purity
>95%
Conjugate
Form
Lyophilized
Purification
purified
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Description: Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein secreted by a variety of vascularized tissues. The reported activities of VEGF include stimulation of endothelial cell growth, angiogenesis and capillary permeability. Mouse VEGF is a 39 kDa homodimeric protein consisting of two 165 amino acid polypeptide chains.
Purity: >95%.
Molecular Weight: 39.0 kDa.
Target Information
The vascular endothelial growth factor (VEGF) family currently includes VEGF-A, VEGF-B, VEGF-C, VEGF-D, VEGF-E, and PIGF. VEGF and its receptor system have been shown to be the fundamental regulators in the cell signaling of angiogenesis. Most tumors have the absolute requirement of angiogenesis and VEGF has been described as the most potent angiogenic cytokine linked to this process. To date 5 different isoforms of VEGF have been described. These isoforms are generated as the result of alternative splicing from a single VEGF gene. These various isoforms have been shown to bind to two tyrosine-kinase receptors flt-1 (VEGFR-1) and flk-1/KDR (VEGFR-2), which have been found to be expressed almost exclusively on endothelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H-VEGF-165; L-VEGF; M-VEGF-165; vascular endothelial growth factor 165b; vascular endothelial growth factor A; Vascular endothelial growth factor A, long form; Vascular permeability factor; VEGF165; VPF
Gene Aliases: Vegf; Vegfa; Vpf
UniProt ID: (Mouse) Q00731
Entrez Gene ID: (Mouse) 22339
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