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Product Details
RP-87803
Product Specifications
Species
Pig
Expression System
E. coli
Amino acid sequence
MAPTSSSTKN TKKQLEPLLL DLQLLLKEVK NYENADLSRM LTFKFYMPKQ ATELKHLQCL VEELKALEGV LNLGQSKNSD SANIKESMNN INVTVLELKG SETSFKCEYD DETVTAVEFL NKWITFCQSI YSTLT
Molecular weight
15.3 kDa
Class
Recombinant
Type
Protein
Purity
>95% by SDS-Page
Endotoxin concentration
≤1 EU/µg
Activity
ED50 ≤ 1.0 ng/mL; determined by the dose-dependent proliferation of CTLL-2 cells.
Conjugate
Form
Lyophilized
Concentration
0.1 mg/mL
Purification
purified
Storage buffer
10mM sodium phosphate, pH 7.5
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Animal Origin Free
Reconstitute with sterile water at 0.1 mg/mL.
Target Information
Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine; H-IL-2; il 2; IL-2; ILN; Interleukin; Interleukin-2; Interleukin2; Involved in regulation of T cell clonal expansion; M-IL-2; T-cell growth factor; T-cell growth factor (TCGF); TCGF
Gene Aliases: IL-2; IL2; POIL2; TCGF
UniProt ID: (Pig) P26891
Entrez Gene ID: (Pig) 396868
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