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Product Details
PEP-287
Product Specifications
Species Reactivity
Rat
Class
Synthetic
Type
Peptide
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
purified
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
PEP-287 is a 19 amino acid synthetic peptide whose sequence is derived from the rat CSP protein. The sequence of this peptide is (amino to carboxy terminus): E (180)-T-T-Q-L-T-A-D-S-H-P-S-Y-H-T-D-G-F-N (198)
This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product, Cysteine String Protein Alpha, catalog # PA1-776. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.
Reconstitute with 0.1 mL of distilled water.
Target Information
Cysteine string protein alpha (CSPalpha)/DNAJC5 is a synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones. Cysteine-string proteins are membrane-bound proteins associated primarily with nerve endings and synaptic vesicles in the brain. These proteins play an important role in presynaptic function and may be involved in calcium-dependent neurotransmitter release. CSP proteins may act as presynaptic chaperones that assist in maintaining synaptic function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CSP; CSP-beta; Cysteine string protein; Cysteine string protein beta; DnaJ homolog subfamily C member 5; DnaJ homolog subfamily C member 5B
Gene Aliases: Csp; Dnajc5; Dnajc5b; RGD1562486
UniProt ID: (Rat) P60905, (Rat) D3ZD82
Entrez Gene ID: (Rat) 79130, (Rat) 499579
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