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Invitrogen
SARS-CoV-2 Nucleocapsid (B.1.617; B.1.617.1) His-tag Recombinant Protein
Product Details
RP-88462
Product Specifications
Species
Virus
Expression System
E. coli
Amino acid sequence
SARS-CoV-2 nucleocapsid (Accession # YP_009724397.2), amino acids Met1-Ala419 with R203M, D377Y substitutions and an N-terminal His-tag
Tag
His-tag
Molecular weight
46.6 kDa
Class
Recombinant
Type
Protein
Purity
>90% as determined by SDS-PAGE.
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
The mutations were identified in the SARS-CoV-2 varient known as B.1.617 or B.1.617.1
Target Information
SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COVID-19 nucleocapsid; COVID19 Nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
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