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Invitrogen
SARS-CoV-2 Nucleocapsid (P67S, P199L) His-tag Recombinant Protein
Product Details
RP-88460
Product Specifications
Species
Virus
Expression System
E. coli
Amino acid sequence
SARS-CoV-2 nucleocapsid (Accession # YP_009724397.2), amino acids Met1-Ala419 with P67S, P199L substitutions and an N-terminal His-tag
Tag
His-tag
Molecular weight
46.6 kDa
Class
Recombinant
Type
Protein
Purity
>90% as determined by SDS-PAGE.
Conjugate
Form
Lyophilized
Purification
purified
Storage buffer
PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (400 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
The mutations were identified in the SARS-CoV-2 varient known as B.1.2
Target Information
SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: COVID-19 nucleocapsid; COVID19 Nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
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