Solutions for PGT-A | Thermo Fisher Scientific

Ion Reporter Software Aneuploidy Dx Workflows

Analysis of embryo fertilisation prior to implantation (preimplantation genetic testing - PGT-A) provides a tool to prioritise embryos for transfer, helping improve the success rate of in vitro fertilisation (IVF).

The Ion Reporter Software Aneuploidy Dx Workflows is the first brought-to-market, CE-marked preimplantation genetic analysis solution of aneuploidies in embryos prior to transfer to the uterus of women undergoing in vitro fertilisation.

Key features include:

Easy to learn
Get started quickly with minimal training — no prior bioinformatics knowledge required

Fewer manual steps
Helps to minimise staff time with automation

Rapid turnaround
Helps reduce wait time by analysing data in-house

Intended use

Ion Reporter Software (IR) Aneuploidy Dx Workflows (Low-pass whole-genome aneuploidy Dx w1.0 / Low-pass whole-genome aneuploidy Mosaic Dx w1.0) constitute an in vitro diagnostic medical device intended to be used by professionally trained personnel for the qualitative determination of aneuploidies, including the trisomy status of chromosome 21, in genomic DNA derived from human cells using next generation sequencing (NGS). The detection of aneuploidies is intended for screening to be used as preimplantation genomic analysis on biopsies from embryos prior to transfer to the uterus of women undergoing in vitro fertilisation.

Customer testimonial

“Releasing an IVDD version of the ReproSeq analysis workflow shows the Thermo Fisher commitment to the medical laboratories. We have received efficient support from Thermo Fisher to set up and test the ReproSeq Dx analysis workflows. We observed high concordance with our routine results and we were pleased to notice some improvements in the reporting. These early results encourage us to initiate the migration to the CE-marked IVDD Preimplantation Genetic Analysis solution respecting all the steps required for any change in the diagnostic pipeline.”

Marta Cotado, PhD,
Scientific Leader Cytogenomics and Molecular Genetics Genesupport