TSQ Fortis Plus Triple Quadrupole Mass Spectrometer

Accelerate your path to quantitative productivity with the Thermo Scientific TSQ Fortis Plus triple quadrupole mass spectrometer. Enhanced acquisition speed and sensitivity, combined with proven robustness and reliability, deliver next-level performance and value for high-throughput analyses. Simplified operations integrated with powerful Thermo Scientific chromatographic systems and market-leading software ensure users of all skill levels obtain reproducible, high-confidence results that meet laboratory requirements.

Reducing the barrier to productivity: Operational simplicity

Targeted research and routine applications demand fast and responsive instrument control software, with intuitive operations. Predefined method templates with integration to databases, including the Thermo Scientific mzCloud database, enable targeted quantitation method creation based on empirical knowledge. Also, direct method transfer from previous TSQ Fortis mass spectrometers can be loaded and operated without optimization.

Experimental determination of dwell times assigned to transitions is automated based on user-defined chromatographic peak width, with the option of fixed cycle time or optimal number of data points per chromatographic peak. Prioritization settings allow further adjustments. 

Speed with selectivity and sensitivity

Achieve superior acquisition speeds on the TSQ Fortis Plus mass spectrometer, which can acquire 600 SRMs/sec and when combined with a new power supply enables 5 ms polarity switching and allows the required number of data points to be acquired for expanded number of target compounds, even with ultra-high performance liquid chromatography (UHPLC) separation.

The TSQ Fortis Plus mass spectrometer delivers excellent quantitative performance in both selected reaction monitoring (SRM) and high-resolution selected reaction monitoring (H-SRM) for fit-for-purpose selectivity. The enhanced active Q2 collision cell improves product ion transmission, especially for low-mass product ions, which can increase detection efficiency.

Expanded experimental capabilities

Integrated workflow solutions centered on the TSQ Fortis Plus mass spectrometer address regulated requirements targeting a growing list of diverse compounds. New UHPLC and high performance ion chromotagraphy (HPIC) systems maximize sample delivery and separation capabilities, maintaining the sensitivity to meet minimum residue limits without costly sample preparation or derivatization steps. The Thermo Scientific Chromeleon Chromatography Data System (CDS) controls all experimental attributes in a regulated environment to further drive productivity.

Robust and reliable quantitation

Innovative designs in the ion source, neutral blocker, and mass analyzers maintain optimal performance while maximizing instrument uptime. The ion transfer tube enables simple extraction and cleaning in minutes, without breaking the instrument vacuum or requiring instrument calibration. New integrated instrument performance checks and calibration routine reduce manual interaction, maximizing data acquisition and instrument productivity.