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Overview
The blood clotting system plays a vital role in controlling a bleed. This function is accomplished by the coordinated work of platelets and a set of circulating inactive clotting factors. Some individuals have genetic variations in one or more of their clotting factors that may predispose them to developing a clot, usually in a vein.
The most common inherited thrombophilia are:
- Factor V Leiden (V is the Roman numeral for number 5), which affects 3-7% of the population
- Prothrombin gene mutation G20210A, which affects 3-7% of the population
- Deficiency of protein C, protein S, and antithrombin, each affecting less than 1% of the population
Product portfolio
Rely on a comprehensive portfolio of Applied Biosystems™ TaqPath Menu™ Thrombotic Mutations Kits
Want to use our solutions? Contact us for details on our limited time offer. |
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of G20210A polymorphism in F2 gene for Factor II Prothrombin (rs1799963)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of G1691A Polymorphism in F5 gene for Factor V Leiden (rs6025)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of G103T Polymorphism in F13A1 gene for Factor XIII (V34L) (rs5985)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of A1298C polymorphism in the gene for methylenetetrahydrofolate reductase (MTHFR) (rs1801131)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of Polymorphism in SERPINE1 gene for Plasminogen activator inhibitor 1 (PAI-1) (rs1799762)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Intended use and purpose:
- Diagnostics and aid to diagnosis. Detection of C677T polymorphism in the gene for methylenetetrahydrofolate reductase (MTHFR) (rs1801133)
Easy-to-use concept
- Single tube ready-to-use Master Mix contains all components for PCR amplification
- No additional pipetting of PCR reagents is necessary
Contamination reduction
- Master Mix contains uracil-DNA glycosylase (UNG) and dUTPs reducing carryover contamination
Simple laboratory workflow
- Easily combinable with other PCR kits from the TaqPath Menu PCR Kits in one workflow
- Compatible with a wide range of real-time PCR devices
CE-marked kit
Ordering information
For In Vitro Diagnostic Use.
Intended use and regulatory statements of products vary. For specific intended use and regulatory statements, please refer to the Instructions for Use (IFU).
Product availability by country varies. For product availability in your country, check the associated product webpages. TaqPath™ Menu | GeneProof™ assays are manufactured by GeneProof™ and distributed by Thermo Fisher Scientific.
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